Clinical trials: Pelvic Endometriosis
Pelvic Pain
Long-term Management of Patients Surgically Treated for Chronic Pelvic Pain by Minimally Invasive Surgery
It is a retrospective observational study based on the analysis of the medical records of patients treated for chronic pelvic pain and benign gynecological pathologies at the Gynecology Unit of the University Hospital of Modena…
- Trial name
- NCT04652011
- Testing
- Minimally Invasive Gynecologic Surgery, osteopathic manipulative treatment, Pain killer
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Endometriosis, Pelvic Pain
Hyivy Device as Non-hormonal Therapy in Endometriosis
This study seeks to address accessible management of endometriosis-associated chronic pelvic pain by evaluating a novel device used in the home.
- Trial name
- NCT05643131
- Testing
- Hyivy Intravaginal Device
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Hyivy Health Inc
Endometriosis, Pelvic Pain
The Effectiveness of Laparoscopic Treatment of Superficial Endometriosis for Managing Chronic Pelvic Pain
Endometriosis is a chronic, incurable condition that affects about 10% of women of reproductive age. It is defined as a growth of cells similar to the womb lining outside of the womb in the pelvis, and is associated with chronic…
- Trial name
- ESPriT1 (NCT04081532)
- Testing
- surgical removal of superficial peritoneal endometriosis
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- University of Edinburgh
Adenomyosis of Uterus
Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms
The goal of this study/research is to assess the relationship between ultrasound features of the myometrium suggestive of adenomyosis and clinical symptoms of adenomyosis and to establish a reporting system for adenomyosis…
- Trial name
- MUSA3 (NCT07397715)
- Where
- 5 sites in Belgium, Poland and 2 more
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Swiss GO Trial Group
Endometriosis, Pelvic Pain Syndrome
Study on the Outcomes of Patients Treated in Gynecological Emergency Departments for Pelvic Endometriosis or Suspected Pelvic Endometriosis
Adult patients consulting the gynecological emergency department of CHI Créteil during the inclusion period for endometriosis or symptoms suggestive of endometriosis
- Conditions
- Endometriosis, Pelvic Pain Syndrome, Chronic Gynaecological Disease
- Trial name
- NCT07472842
- Testing
- Emergency care for endometriosis
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Pelvic Pain, Endometriosis
The Women's Health Study: From Adolescence to Adulthood
In order to learn more about women's health issues that occur over the lifespan, the Women's Health Study: from Adolescence to Adulthood is building a biorepository and database.
- Conditions
- Pelvic Pain, Endometriosis, Dysmenorrhea, Infertility
- Trial name
- WHS:A2A (NCT01738204)
- Where
- 2 sites in United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Endometriosis
Extension to Study on Efficacy and Safety of Linzagolix for the Treatment of Endometriosis-associated Pain
The primary objective of this extension study is to assess the maintenance of efficacy of linzagolix administered orally once daily for up to an additional 6 months (for up to 12 months of treatment in total) in women who have…
- Trial name
- EDELWEISS 5 (NCT04372121)
- Testing
- 75 mg linzagolix tablet, 200 mg linzagolix tablet, Add-back capsule (E2 1 mg / NETA 0.5 mg)
- Where
- 25 sites in United States, Canada and 1 more
- Volunteers
- 30 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Endometriosis
A Phase 3 Study to Confirm the Efficacy and Safety of Linzagolix to Treat Endometriosis-associated Pain
The primary objective of this study is to demonstrate the efficacy and safety of linzagolix administered orally once daily for 3 months at a dose of 75 mg alone or of 200 mg in combination with add-back hormone replacement…
- Trial name
- NCT03986944
- Testing
- 75 mg linzagolix tablet, 200 mg linzagolix tablet, Add-back capsule (E2 1 mg / NETA 0.5 mg)
- Where
- 112 sites in United States, Canada and 1 more
- Volunteers
- 85 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Elective Fertility Preservation
Study of the Prevalence of Endometriosis and Adenomyosis
Our study aims to assess the prevalence of adenomyosis and endometriosis in patients consulting for elective fertility preservation through the diagnosis of these pathologies by transvaginal pelvic ultrasound.
- Trial name
- PrevADEOSE (NCT06211569)
- Testing
- Usual follow-up
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Deep Endometriosis
3D Modeling of Deep Endometriosis From Pelvic MRI
This retrospective monocentric study aims to assess the feasibility and clinical relevance of three-dimensional (3D) modeling of deep endometriosis lesions derived from pelvic MRI.
- Trial name
- ENDO-3D (NCT07864883)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Endometriosis, Pelvic Pain
Cannabidiol for the Treatment of Pelvic Pain in Endometriosis (DREAMLAND)
The objective of this work is to conduct a randomized, double-blind, placebo-controlled clinical trial to assess the efficacy and safety of cannabis extract in women with endometriosis who have already undergone hormonal…
- Trial name
- DREAMLAND (NCT05670353)
- Testing
- Cannabis Derivatives, Hormonal Contraceptive Agents
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Pelvic Pain, Endometriosis
Postoperative Narcotic Use After Laparoscopic Gynecologic Surgery
This will be a prospective, randomized, double blinded placebo-controlled study at Erlanger hospital. Eligible patients who provide consent will be randomized into one of two arms receiving continuous intra-peritoneal local…
- Conditions
- Pelvic Pain, Endometriosis, Pelvic Prolapse
- Trial name
- NCT04118777
- Testing
- Ropivacaine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Tennessee, Chattanooga
Endometriosis
Impact of Magnetic Stimulation on Pain in Endometriosis Patients
Many women with endometriosis still experience pain despite surgical and medical treatment. Over-the-counter painkillers are usually helpful in alleviating this pain.
- Trial name
- NCT07265687
- Testing
- Magnetic stimulation
- Volunteers
- 30 people
- Sponsor
- Kantonsspital Winterthur KSW
Gynecologic Disease, Endometriosis
Ultrasound Evaluation of the Pelvis in Women with Suspected Endometriosis Scheduled for Laparoscopic Surgery
An international multicenter observation study to evaluate the diagnostic accuracy and predictive value of ultrasound using the IDEA terminology in the detection of deep endometriosis in women scheduled for surgery.
- Conditions
- Gynecologic Disease, Endometriosis, Endometriosis, Rectum, Endometriosis of Colon
- Trial name
- IDEA1 (NCT04171297)
- Testing
- Ultrasound evaluation of DE
- Where
- 3 sites in Australia, Belgium and 1 more
- Volunteers
- 1,866 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Endometriosis
Study of Real Clinical Practice to Evaluate the Effects of Oral Dydrogesterone for Treatment of Confirmed Endometriosis
A non-interventional, observational program to assess the effects of dydrogesterone (Duphaston®) 6-months-administration in patients with confirmed endometriosis in a post-marketing setting in the Russian Federation
- Trial name
- NCT03690765
- Testing
- Duphaston® (Dydrogesterone)
- Where
- 21 sites in Russia
- Volunteers
- 350 people
- Sponsor
- Abbott
Pelvic Endometriosis, Endometriosis Outside Pelvis
Prospective Evaluation of Near-infrared Fluorescence Imaging Use as a Supportive Tool in Deep Infiltrating Endometriosis Surgery
The aim of the study is to establish a new and more accurate method to visualize the peritoneal changes caused by endometriosis using Indocyanine Green mediated fluorescence imaging.
- Trial name
- GRE-Endo-2 (NCT03935165)
- Testing
- Indocyanine Green
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- Catholic University of the Sacred Heart
Endometriosis, Pelvic Pain
Medical Treatment of Endometriosis-Associated Pelvic Pain
The Specific Aim of this project is to compare the efficacy and cost-effectiveness of continuous oral contraceptives versus leuprolide/norethindrone in the treatment of endometriosis-associated chronic pelvic pain.
- Trial name
- NCT00229996
- Testing
- Oral Contraceptive, Depot-Leuprolide/Norethindrone
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Endometriosis
Clinical Study to Compare Efficacy and Safety of Indinol Forto® 200 mg Capsules and Visanne 2 mg Tablets in Treatment of Endometriosis
Prospective open-label randomized parallel groups study to compare efficacy and safety of Indinol Forto® 200 mg capsules and Visanne 2 mg tablets in treatment of endometriosis.
- Trial name
- Baikal (NCT07164183)
- Testing
- Indole-3-carbinol, Dienogest
- Where
- 8 sites in Russia
- Volunteers
- 290 people
- Sponsor
- Alcea
Endometriosis, Post Operative Pain
The Using Postoperative Ketamine and Exploring the Effect on Endometriosis Pain (UPKEEEP) Study
This is a randomized, single blinded, placebo-controlled trial to study the effectiveness of a subanesthetic dose (0.6 mg/kg) of ketamine versus placebo (saline) on postoperative pain and pain on adult female chronic pelvic pain…
- Trial name
- NCT05229653
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- NYU Langone Health
Endometriosis
A Clinical Study to Evaluate the Safety and Efficacy of Elagolix in Subjects With Moderate to Severe Endometriosis-Associated Pain
A randomized study evaluating the safety and efficacy of elagolix in the management of moderate to severe endometriosis-associated pain in adult premenopausal female participants.
- Trial name
- ELARIS EM-I (NCT01620528)
- Testing
- elagolix
- Volunteers
- 872 people
- Sponsor
- AbbVie (prior sponsor, Abbott)