Clinical trials: Pelvic Endometriosis
Endometriosis, Endometriosis-related Pain
Relugolix for Endometriosis Associated Pain
Endometriosis is a chronic, estrogen-dependent condition frequently associated with pelvic pain and reduced quality of life. Relugolix combination therapy (CT), an oral GnRH receptor antagonist-based treatment, has demonstrated…
- Conditions
- Endometriosis, Endometriosis-related Pain, Pelvic Pain Syndrome
- Trial name
- RELAX (NCT07440043)
- Testing
- Patients with a diagnosis of endometriosis receiving treatment with Relugolix CT, according to clinical practice,
- Volunteers
- 33 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Endometriosis
Effect of Physical Activity and Pain Education on Endometriosis-associated Pain
Endometriosis is a benign gynecological condition where the uterine endometrium is located outside the uterus. The condition affects up to 10% of women of fertile age and up to 70% of women with endometriosis have symptoms with…
- Trial name
- NCT05091268
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 83 people
- Sponsor
- University Hospital, Akershus
Endometriosis
Post-operative Ovarian Adhesion Study in Women With Endometriosis
Endometriosis is a common gynaecological condition which typically present with pelvic pain and fertility problems. It is caused by tissues which are similar to the lining of the womb growing inside the women's pelvis.
- Trial name
- NCT01989260
- Testing
- Anti-adhesive gel
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University College London Hospitals
Chronic Pain, Endometriosis
THE EFFECT OF tDCS IN THE TREATMENT OF CHRONIC PELVIC PAIN ASSOCIATED WITH ENDOMETRIOSIS
The purpose of this study is to determine if transcranial direct current stimulation (tDCS) is effective in the treatment of chronic pelvic pain associated with endometriosis
- Trial name
- tDCS (NCT02161302)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Endometriosis
Predicting the Pain Outcome of Surgery for Endometriosis
This study aims to determine whether the investigators can predict who will get benefit in terms of their pain from surgery for more severe forms of endometriosis.
- Trial name
- PrePOSE (NCT07313345)
- Testing
- Surgical treatment of endometriosis
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Oxford
Endometriosis
Efficacy of Trace Elements in the Treatment of Endometriosis: a Pilot Study
The primary objective of this pilot study is to evaluate the efficacy of trace elements, versus placebo, on the reduction of pain in endometriosis of an American Fertility Society (AFSr) score of 2 to 4, combined or not to an…
- Trial name
- NCT02437175
- Testing
- ENDO 1/ENDO 2
- Where
- Belgium
- Volunteers
- 99 people
- Sponsor
- Laboratoires Pronutri
Endometriosis
Interaction Between Decidual Cells and NK Cells in Endometriosis
Endometriosis is a chronic gynecological disease characterized by the presence of endometrial-like tissue outside the uterus and is frequently associated with pelvic pain and infertility.
- Trial name
- PAINLESS (NCT07652593)
- Testing
- Biological Sample Collection
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hopital Foch
Adenomyosis, Fibroid Uterus
Fertility Limiting Diseases of Pelvic Organs and Their Influence on Receptivity of Endometrial Cavity: Prospective Clinical Trial
In this project, we will characterize the effects of fertility limiting diseases of pelvic organs on the receptivity of the endometrium.
- Conditions
- Adenomyosis, Fibroid Uterus, Endometriosis
- Trial name
- REAdME (NCT06991595)
- Testing
- cytoreductive resection of adenomyosis, myomectomy, resection of endometriosis, hysteroscopy
- Where
- Czechia
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Endometriosis
Treatment of Chronic Pelvic Pain Due to Endometriosis by Transcutaneous Auricular Vagus Nerve Stimulation
6-10% of women of childbearing age suffer from endometriosis, which is mainly manifested by dysmenorrhea, non-menstrual pelvic pain and dyspareunia.
- Trial name
- Stim-Endom (NCT04177511)
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Hopital Foch
Endometriosis, Deep Endometriosis
The Association Between Deep Endometriosis and the Occurrence of Colorectal Carcinoma
The goal of this study is to identify the molecular or genetic mechanisms that may predispose patients with bowel endometriosis to an increased risk of colorectal carcinoma.
- Conditions
- Endometriosis, Deep Endometriosis, Bowel Endometriosis, Colorectal Carcinoma
- Trial name
- NCT07386431
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Endometriosis, Dyspareunia
Transvaginal Low-level Laser Therapy to Improve Pelvic Pain and Sexual Function in Patients with Endometriosis.
Dyspareunia is defined as pain with penetrative sexual intercourse. Women with endometriosis have a nine-fold increased risk of dyspareunia, when compared to the general female population.
- Conditions
- Endometriosis, Dyspareunia, Pelvic Pain
- Trial name
- NCT05540353
- Testing
- Transvaginal photobiomodulation
- Where
- 6 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Pelvic Pain, Endometriosis
Effect of Tele-Yoga on Pain, Fatigue, and Quality of Life in Endometriosis
This study aims to examine the effects of Tele-yoga on chronic pelvic pain, fatigue, and quality of life in patients diagnosed with endometriosis.
- Trial name
- NCT07241637
- Testing
- Tele-Yoga Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara University
Endometriosis, Chronic Pelvic Pain
Pelvic Pain in Women With Endometriosis
This study will examine pelvic pain associated with endometriosis and explore better approaches to treatment. In women with endometriosis, uterine tissue grows outside the uterus.
- Trial name
- NCT00073801
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Dysmenorrhea, Dyspareunia
Study Evaluating the Safety and Efficacy of ERB-041 on Reduction of Symptoms Associated With Endometriosis in Reproductive-Aged Women
The purpose of the study is to evaluate the efficacy and safety of two doses of ERB-041 (75 mg and 150 mg) relative to placebo on the relief of endometriosis-related symptoms (dysmenorrhea, pelvic pain, and deep dyspareunia) in…
- Conditions
- Dysmenorrhea, Dyspareunia, Endometriosis, Pelvic Pain
- Trial name
- NCT00318500
- Testing
- ERB-041
- Where
- 70 sites in United States, Australia and 5 more
- Volunteers
- 150 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Pelvic Pain Associated With Refractory Endometriosis
A Safety & Efficacy Study of BGS649 in Women With Refractory Endometriosis
The purpose of this study is to determine efficacy, safety, tolerability and pharmacokinetics of multiple doses of BGS649 with concurrent daily administration of combined oral contraception in patients with refractory…
- Trial name
- NCT01116440
- Testing
- BGS649
- Where
- 44 sites in United States, Puerto Rico
- Volunteers
- 27 people
- Sponsor
- Mereo BioPharma
Endometriosis (Diagnosis)
Comparison of Elagolix and OCPs in Reducing Endometriosis Associated Pelvic Pain
This study is designed to provide direct evidence on the relative effectiveness and safety of Elagolix versus OCPs, helping physicians make more tailored treatment decisions.
- Trial name
- NCT07532876
- Testing
- Elagolix, Oral Contraceptive (OC)
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Pak Emirates Military Hospital
Endometriosis, Dysmenorrhea
Effect of Propolis Administration for Dysmenorrhea in Endometriosis Patient With Levonorgestrel Implant Therapy
The goal of this clinical trial is to investigate the effect of propolis administration on dysmenorrhea in endometriosis patient.
- Trial name
- NCT05770297
- Testing
- Propolis
- Where
- Indonesia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Endometriosis
Whole-Body Cryotherapy as a Non-Pharmacological Treatment to Reduce Chronic Pelvic Pain and Improve Quality of Life in People With Endometriosis
The aim of this study is to investigate whether whole-body cryotherapy (a brief exposure to very cold temperatures) can help reduce pain and improve quality of life in people living with endometriosis, and whether it may…
- Trial name
- CHILL-Endo (NCT07603960)
- Testing
- Whole-Body Cryotherapy
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Edinburgh
Endometriosis
The Impact of Yoga on Endometriosis-Related Pain
The central hypothesis of the investigators is that the practice of yoga will result in an improvement of endometriosis related pain symptoms for women with endometriosis.
- Trial name
- NCT06559852
- Testing
- Yoga
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Milton S. Hershey Medical Center
Pelvic Pain, Endometriosis
Postoperative Narcotic Use After Laparoscopic Gynecologic Surgery
This will be a prospective, randomized, double blinded placebo-controlled study at Erlanger hospital. Eligible patients who provide consent will be randomized into one of two arms receiving continuous intra-peritoneal local…
- Conditions
- Pelvic Pain, Endometriosis, Pelvic Prolapse
- Trial name
- NCT04118777
- Testing
- Ropivacaine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Tennessee, Chattanooga