Clinical trials: Pelvic Inflammatory Disease
Endometritis
The Optimal Time for Intravenous Antibiotic Prophylaxis in Elective Cesarean Section
Objective: To determine the optimal time for intravenous antibiotic prophylaxis administration in pregnant women undergoing elective cesarean section to minimize postpartum infectious complication for both the mother \& neonate.
- Trial name
- NCT02742948
- Testing
- ceftriaxone
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cervical Carcinoma, Endometrial Carcinoma
Comparison of Proton or Intensity Modulated Radiation Therapy After Surgery for Endometrial or Cervical Cancer
This early phase I trial compares the side effects between patients treated with proton radiation therapy versus intensity modulated radiation therapy after surgery for the treatment of endometrial or cervical cancer.
- Conditions
- Cervical Carcinoma, Endometrial Carcinoma, Endometriosis, Pelvic Inflammatory Disease
- Trial name
- NCT04567771
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Radiation Therapy
- Where
- 3 sites in United States
- Volunteers
- 121 people
- Sponsor
- Mayo Clinic
Antibiotics Causing Adverse Effects in Therapeutic Use
Role of Prophylactic Antibiotics in Preventing Pelvic Infection After Surgical Evacuation
To determine the role of antibiotic prophylaxis in the surgical management of miscarriage.
- Trial name
- NCT05040334
- Testing
- Group 1: Antibiotic receiving group
- Where
- Egypt
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infection; Cesarean Section, Surgical Wound Infection
Controlled Clinical Trial of Supplemental Oxygen for the Prevention of Post-Cesarean Infectious Morbidity
Previous studies have demonstrated that patients who undergo surgery while they under general anesthesia have fewer wound infections if they receive higher concentrations of oxygen but this has never been studied in women who are…
- Conditions
- Infection; Cesarean Section, Surgical Wound Infection, Endometritis
- Trial name
- Peri-Op (NCT00603603)
- Testing
- 80% inhaled oxygen via non-rebreather mask, 30% inhaled oxygen via nasal cannula
- Where
- United States
- Volunteers
- 606 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Pelvic Inflammatory Disease (PID)
Technology Enhanced Community Health Nursing (TECH-N) Study
The investigators are enrolling 350 young women 13-25 years old diagnosed with pelvic inflammatory disease (PID) in Baltimore and randomize them to receive community health nurse (CHN) clinical support using a single post-PID…
- Trial name
- TECH-N (NCT01640379)
- Testing
- Technology Enhanced Community Health Nursing
- Where
- United States
- Volunteers
- 286 people
- Sponsor
- Johns Hopkins University
Radiology, Inflammatory Bowel Diseases
CT Using MBIR in Crohn's Disease: Prospective Clinical Evaluation of Diagnostic Efficacy, Safety and Patient Outcome.
This study aims to assess the use of low dose CT reconstructed with MBIR for the assessment of patients with inflammatory bowel disease who need CT to assess for disease complications.
- Trial name
- NCT03140306
- Testing
- Patients who have had split dose CT
- Where
- Ireland
- Volunteers
- 56 people
- Sponsor
- University College Cork
Endometritis Postpartum, Endometritis
Antibiotic Prophylaxis in Ragged Placental Membranes
In some centres, women are routinely given a course of antibiotics postnatally if ragged placental membranes were present at delivery. The investigators examined the necessity such an intervention.
- Conditions
- Endometritis Postpartum, Endometritis, Membranes; Retained
- Trial name
- NCT03459599
- Testing
- Prophylactic antibiotics, No prophylaxis (Amox-clav withheld)
- Volunteers
- 716 people, healthy volunteers welcome
- Sponsor
- Sarawak General Hospital
Chlorhexidine Gluconate Cloths, Infection; Cesarean Section
STRIPES Study: Study To Reduce Infection Post cEsarean Section
The objective of this study is to determine if the use of chlorhexidine gluconate cloths prior to cesarean section reduce the rate of infectious morbidity (i.e. surgical site infections, endometritis).
- Conditions
- Chlorhexidine Gluconate Cloths, Infection; Cesarean Section, Infectious Morbidity, Surgical Site Infections
- Trial name
- NCT02402907
- Testing
- 2% chlorhexidine gluconate (CHG) cloth
- Where
- United States
- Volunteers
- 1,356 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hip Osteoarthritis
OXINIUM◊ DH Total Hip Arthroplasty Pivotal Study
The purpose of this study is to monitor safety of the participants implanted with the OXINIUM◊ DH Hip System up to 10-years post-implantation
- Trial name
- NCT02353377
- Testing
- OXINIUM DH Hip System, BIOLOX◊
- Volunteers
- 413 people
- Sponsor
- Smith & Nephew, Inc.
Metrorrhagia, Menorrhagia
Surgical Success After Laparoscopic vs Abdominal Hysterectomy
The purpose of the proposed pilot study is to investigate the effectiveness, cost, safety, and long-term impact on quality of life of laparoscopic hysterectomy (LH) in relation to abdominal hysterectomy (AH) for the treatment of…
- Conditions
- Metrorrhagia, Menorrhagia, Leiomyoma, Adenomyosis
- Trial name
- NCT01793584
- Testing
- Laparoscopic hysterectomy, Abdominal hysterectomy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Endometritis, Cesarean Section; Infection
Two-drug Antibiotic Prophylaxis in Scheduled Cesarean Deliveries
Cesarean deliveries are the most common surgical procedure performed in the United States. A significant decrease in cesarean delivery associated maternal morbidity has been achieved with preoperative prophylactic single-dose…
- Conditions
- Endometritis, Cesarean Section; Infection, Wound Infection
- Trial name
- NCT03960970
- Testing
- Azithromycin 500 mg, Mefoxin 2g
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- RWJ Barnabas Health at Jersey City Medical Center
Pelvic Pain, Pelvic Pain Syndrome
Efficacy of Resistive Capacitive Monopolar Radiofrequency in the Physiotherapeutic Treatment of Chronic Pelvic Pain: RCT
This study evaluates if the application of resistive capacitive monopolar radiofrequency therapy associated with physiotherapeutic techniques and pain education provides benefits with respect to physiotherapy and pain education…
- Conditions
- Pelvic Pain, Pelvic Pain Syndrome, Chronic Pain, Chronic Pain Syndrome
- Trial name
- NCT03797911
- Testing
- Active resistive capacitive monopolar radiofrequency with physiotherapeutic techniques and pain education, Inactive resistive capacitive monopolar radiofrequency with physiotherapeutic techniques and pain education
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- RAPbarcelona
Non-inflammatory Degenerative Joint Disease (NIDJD), Avascular Necrosis
MDR - Longevity IT Oblique and Offset Liners
The objective of this retrospective enrollment/prospective follow-up consecutive series PMCF study is to collect data confirming safety, performance, and clinical benefits of the Longevity IT Oblique and Offset liners when used…
- Conditions
- Non-inflammatory Degenerative Joint Disease (NIDJD), Avascular Necrosis, Protrusio Acetabuli, Traumatic Arthritis
- Trial name
- NCT05980234
- Testing
- Total Hip Arthroplasty with Longevity IT Oblique Liners, Total Hip Arthroplasty with Longevity IT Offset Liners
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Zimmer Biomet
Cervical Cancer, Uterine Cervical Neoplasm
Effect of an Anti-inflammatory Diet on Patients With Cervical Cancer
During radiation therapy (RT) to pelvic tumors, the small intestine, colon and rectum are inevitably included in the radiation field and are healthy tissues that suffer damage as an adverse effect.
- Conditions
- Cervical Cancer, Uterine Cervical Neoplasm, Pelvic Inflammatory Disease, Radiation Toxicity
- Trial name
- NCT03994055
- Testing
- Omega-3 fatty acids, Antioxidants, Soluble fiber
- Where
- Mexico
- Volunteers
- 136 people
- Sponsor
- National Institute of Cancerología
Bacterial Vaginoses
A Randomized Controlled Trial of Treatment of Bacterial Vaginosis
This is a double-blinded, placebo controlled, multi-center randomized trial of 482 pregnant women who are diagnosed with Bacterial Vaginosis (BV) in the late 3rd trimester (>34 weeks).
- Trial name
- NCT04578015
- Testing
- Metronidazole
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Ohio State University
Colitis, Ulcerative, Ileal Pouches
MRI in Normal Ileal Pouches, and a Feasibility Study of Dynamic MRI Enema and Defaecating MRI Pouchography
A study to investigate the prevalence of pelvic collections in a representative sample of participants with normally functioning ileal pouches.
- Trial name
- NCT02925260
- Testing
- MRI with ileal pouch contrast and enema.
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- London North West Healthcare NHS Trust
Pelvic Inflammatory Disease
Improving Primary Care Follow-up for Patients With Pelvic Inflammatory Disease
The investigators hypothesize that text message reminders to girls diagnosed with pelvic inflammatory disease (PID) in the emergency department (ED) will improve follow-up to their primary care provider (PCP) after being…
- Trial name
- NCT01299259
- Testing
- Text Message Reminders
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Children's Hospital of Philadelphia
Chronic Pelvic Pain
The Clinical Effect of Fuke Qianjin Capsule on Chronic Pelvic Pain Caused by Pelvic Inflammation
A prospective random control clinical trials to research Fuke Qianjin capsule's effects on ameliorating the pain caused by chronic pelvic disease.
- Trial name
- NCT03251560
- Testing
- Fuke Qianjin capsule
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Aijun Sun
Endometritis
Prophylactic Antibiotics for Manual Removal of Retained Placenta in Vaginal Birth: a Randomized Controlled Trial
Background: There is scarce evidence regarding the necessity of antibiotic prophylaxis in manual revision of the uterus after labor in cases of residual placenta.
- Trial name
- NCT01945450
- Testing
- Antibiotic prophylaxis, Ampicillin, Gentamycin
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Hadassah Medical Organization
Endometritis; Chronic, Subfertility
The FLORA-project: in Search for the Microbial Cause of Chronic Endometritis and the Most Appropriate Treatment to Obtain a Successful Pregnancy IVF/ICSI
Chronic endometritis is an inflammatory condition of the endometrium. This inflammation can negatively affect fertility and pregnancy. The pathology is frequently (+-10%) observed in women with fertility problems.
- Trial name
- FLORA (NCT05337072)
- Testing
- Microbiome study
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel