Clinical trials: Pelvic Neoplasm
Empty Pelvis Syndrome, Pelvic Exenteration
PelvEx - Beating the Empty Pelvis Syndrome
The empty pelvis syndrome is an unsolved and poorly defined problem severely affecting patients that have pelvic exenteration surgery, and also the teams looking after them.
- Conditions
- Empty Pelvis Syndrome, Pelvic Exenteration, Pelvic Neoplasm, Pelvic Cancer
- Trial name
- NCT05683795
- Testing
- Consensus study
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Adenomyosis, Fibroid Uterus
Fertility Limiting Diseases of Pelvic Organs and Their Influence on Receptivity of Endometrial Cavity: Prospective Clinical Trial
In this project, we will characterize the effects of fertility limiting diseases of pelvic organs on the receptivity of the endometrium.
- Conditions
- Adenomyosis, Fibroid Uterus, Endometriosis
- Trial name
- REAdME (NCT06991595)
- Testing
- cytoreductive resection of adenomyosis, myomectomy, resection of endometriosis, hysteroscopy
- Where
- Czechia
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Endometrial Carcinoma, Prostate Carcinoma
Screening and Staging of Benign vs Malignant Pelvic Abnormalities
This study evaluates whether newly developed non-FDA approved image processing techniques [Adaptive Image Reconstruction (AIR Recon) Deep Learning (DL) and Sonic DL] can provide improved quality and decreased time compared to…
- Trial name
- NCT07407959
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Prostate Neoplasm
COHORT Trial in Clinical Pelivc Lymph Node Metastatic Prostate Cancer
In local advanced prostate cancer patients with clinically positive metastatic regional lymph node, the optimal treatment is still unanswered.
- Trial name
- NCT03241537
- Testing
- Intensity modulated radiotherapy
- Where
- South Korea
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Colon Cancer, Colon Polyp
Feasibility and Safety of Single Port Robot in Colorectal Procedures
The purpose of this study is to evaluate the safety and feasibility of using the Single Port (SP) robot (daVinci, Intuitive Surgical) to perform single port robotic colon surgery and transanal robotic surgery.
- Conditions
- Colon Cancer, Colon Polyp, Rectal Cancer, Diverticulitis
- Trial name
- NCT03700593
- Testing
- Single Port Robotic Colorectal Surgery
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Marks Colorectal Surgical Associates
Pelvic Radiotherapy, Gynecological Cancer
Laser Therapy Following Radiotherapy for Gynecological Cancer
Women with a history of pelvic radiotherapy due to gynecological cancer, will receive laser therapy for the management of genitourinary syndrome of menopause.
- Conditions
- Pelvic Radiotherapy, Gynecological Cancer, Dyspareunia, Vaginal Dryness
- Trial name
- NCT03714581
- Testing
- Microablative Fractional CO2 Laser Therapy
- Where
- Greece
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Dysmenorrhea (Disorder), Dysmenorrhea Primary
Mechanistic Characterization of Uterine Pain
There are limited treatment options for management of dysmenorrhea, and the physiological processes they affect are not completely understood.
- Conditions
- Dysmenorrhea (Disorder), Dysmenorrhea Primary, Dysmenorrhea Secondary, Endometrial Diseases
- Trial name
- MCUP (NCT04145518)
- Testing
- Naproxen Sodium
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Anxiety
Surveillance Pelvic Examination Anxiety: Brief Coping Skills Intervention
The purpose of this study is to test the feasibility and acceptability of a brief coping skills training program addressing anxiety and pain related to surveillance pelvic examinations for female gynecologic cancer survivors.
- Trial name
- PEACE (NCT05285306)
- Testing
- PEACE Program
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Duke University
Cancer, Pelvic Floor Dysfunction
Pelvic Floor Dysfunction in Cancer Survivors.
Introduction: Pelvic floor dysfunctions (PFD) represent a major public health problem manifested through lower urinary tract symptoms (LUTS), anorectal and sexual dysfunction.
- Trial name
- NCT03979755
- Testing
- Application of questionnaires
- Where
- Brazil
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Neoplasm Metastasis, Carcinoma
Helical Tomotherapy as a Radiotherapy Technique for Treating Pelvic and Abdominal Metastases
Radiation treatment is often used to treat cancer that has spread to the abdomen. It can be very effective at relieving symptoms such as pain, but the radiotherapy itself can cause side-effects such as cramping and diarrhea.
- Trial name
- NCT00129051
- Testing
- Tomotherapy
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alberta Health services
Radiation Disease
Pelvic Radiation Disease in Childhood Cancer Survivors
This study aims to characterise the impact of radiotherapy on physical symptoms and quality of life in childhood and young adult cancer survivors.
- Trial name
- NCT05533541
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Rectal Cancer
Efficacy of Stimulation of the Efferent Loop and Rehabilitation of the Pelvic Floor in the Quality of Life of Patients Who Underwent Anterior Resection of the Rectum (ENESP): Randomized Clinical Trial
Many of the patients operated with sphincter preservation will present an alteration of bowel function and defecation. This dysfunction is variable in its symptoms and severity, and manifests itself in the form of urgency…
- Trial name
- ENESP (NCT04569331)
- Testing
- Stimulation of efferent loop, Rehabilitation pelvic floor
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Labor, Pelvic Floor Disorder
Pelvic Floor Ultrasound Before Induction of Labour and Labour Outcome
Pregnancy and vaginal birth are the main causes of pelvic floor disorders such as urinary incontinence and pelvic organ prolapse.
- Conditions
- Labor, Pelvic Floor Disorder, Labor Stage, Second, Induced Labor
- Trial name
- LEVATOR-IOL (NCT07797387)
- Testing
- Three-dimensional transperineal pelvic floor ultrasound
- Where
- Italy
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Bladder Cancer, Kidney Cancer
Biomarkers in Patients With Kidney Cancer or Cancer of the Urothelium and in Healthy Participants
RATIONALE: Studying samples of blood and urine from patients with cancer and from healthy participants in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
- Conditions
- Bladder Cancer, Kidney Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral Cancer
- Trial name
- NCT00900276
- Testing
- immunologic technique, laboratory biomarker analysis, mass spectrometry
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Pelvic Neoplasms
Treatment of Hemorrhagic Radiation Proctitis Using the Halo System
This study involves evaluating a procedure in which the study device, the HALO90 Ablation catheter, is used to heat a thin layer of tissue lining the rectum using radiofrequency (RF) energy in subjects suffering from radiation…
- Trial name
- NCT01103492
- Testing
- HALO90 Ablation catheter
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Prostate Cancer (Adenocarcinoma), Radical Prostatectomy
Evaluation of Pelvic Floor Function and Psychosocial Sequelae Following Radical Prostatectomy for Prostate Cancer
This observational cross-sectional study aims to evaluate the effects of radical prostatectomy for prostate cancer on pelvic floor function and psychosocial well-being.
- Conditions
- Prostate Cancer (Adenocarcinoma), Radical Prostatectomy, Urinary Incontinence (UI), Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- NCT07693647
- Testing
- No Interventions
- Where
- Spain
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Prostate Cancer, Bladder Cancer
Use of PET/MRI Tracer to Further Understanding of Prostate Cancer Development
The purpose of this study is to develop a novel technique for integrated PET/MRI tracer kinetic analysis for urologic malignancy.
- Trial name
- NCT02106416
- Testing
- PET/MRI
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Uterine Fibroids, Endometriosis
AMH Levels Change During Treatment With GnRh Agonist
To evaluate the variation of AMH levels in women undergoing treatment with GnRHa, and to assess whether this variation correlates with changes in the antral and pre-antral follicle ultrasonographic count (AFC).
- Conditions
- Uterine Fibroids, Endometriosis, Endometriosis of Uterus, Pelvic Pain
- Trial name
- NCT02086279
- Testing
- GnRH analogue
- Where
- Italy
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Abnormal Uterine Bleeding, Uterine Bleeding
Outcomes on Abdominal Versus Vaginal Morcellation At Time of Hysterectomy
The purpose of the study is to investigate differences in perioperative and postoperative outcomes between the abdominal (AM) versus vaginal (VM) routes of contained morcellation in participants undergoing laparoscopic total…
- Conditions
- Abnormal Uterine Bleeding, Uterine Bleeding, Fibroid Uterus, Surgery
- Trial name
- NCT04434066
- Testing
- Total Laparoscopic Hysterectomy
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Rectum Cancer, Pelvic Cancer
Assessment of DW-MRI Measures : Reproducibility and Repeatability in Pelvic Imaging on MR-Linac With Healthy Volunteers
This study evaluates the reliability of functional MRI measurements in pelvic disease through quantifying repeatability and reproducibility, using healthy volunteers.
- Trial name
- PILLAR (NCT06458725)
- Testing
- Magnetic Resonance Imaging (MRI)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jules Bordet Institute