Clinical trials: Pelvic Neoplasm
Pelvic Neoplasm
BladdEr Full OR Empty for Pelvic Radiation Therapy
The present study evaluates empty and full bladder protocols for radiation therapy of genitourinary (GU), gynecological (Gyn), and gastrointestinal (GI) malignancies of the pelvis.
- Trial name
- BEFORE (NCT06651697)
- Testing
- Radiation therapy
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of California, San Diego
Bladder Cancer, Muscle-Invasive Bladder Carcinoma
Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy
Subjects will be randomized into 2 groups (stent or no stent) prior to radical cystectomy with ileal conduit urinary diversion (RCIC). They will follow the standard of care and be enrolled in the study for 12 months post-op.
- Conditions
- Bladder Cancer, Muscle-Invasive Bladder Carcinoma, Urothelial Carcinoma, Pelvic Malignancy
- Trial name
- NCT07234968
- Testing
- Ureteral Stent Placement, No Ureteral Stent, Indocyanine Green with Fluorescence Imaging
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Thomas Jefferson University
Rectal Cancer Recurrent, Pelvic Exenteration
Postoperative Results and Outcomes in Surgical Pelvic Exenteration
The purpose of this study is to evaluate the feasibility of a standardized surgical and care process for patients with locally advanced or recurrent rectal cancer that has spread to nearby pelvic organs.
- Conditions
- Rectal Cancer Recurrent, Pelvic Exenteration, Advanced Rectal Cancer
- Trial name
- PROS-PE (NCT07395505)
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Chang Gung Memorial Hospital
Endometriosis, Deep Endometriosis
The Association Between Deep Endometriosis and the Occurrence of Colorectal Carcinoma
The goal of this study is to identify the molecular or genetic mechanisms that may predispose patients with bowel endometriosis to an increased risk of colorectal carcinoma.
- Conditions
- Endometriosis, Deep Endometriosis, Bowel Endometriosis, Colorectal Carcinoma
- Trial name
- NCT07386431
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Pelvis Neoplasms
Pelvis Adaptive Radiotherapy (ART)
Pelvis Adaptive radiotherapy (ART) is a two phase study looking at using adaptive radiotherapy to help reduce toxicity for cancer patients having radiotherapy in the pelvic region.
- Trial name
- Pelvis ART (NCT06650033)
- Testing
- Adaptive radiotherapy +/- margin reduction, Image guided radiotherapy
- Where
- Australia
- Volunteers
- 280 people
- Sponsor
- Royal North Shore Hospital
Long Term Cancer Side Effects, Supportive Care in Cancer
Optimize the Support of Patients in Pelvic Onco-gynecology Through Adapted Support Care in the Post-cancer Period. AFTERGYN Pilot Phase
While the sequelae and toxicities after ovarian and endometrial cancer treatments are well described in the literature, the actual needs of patients for supportive oncology care remain poorly documented.
- Conditions
- Long Term Cancer Side Effects, Supportive Care in Cancer, Cancer Survivorship Care Plan, Advanced Nurse Practitioner
- Trial name
- AFTERGYN (NCT05731661)
- Testing
- Day hospitalization in support care with meeting with support care professionals and coordination of actions by the advanced practice nurse, Delivery of useful information according to support care needs, concerning support care professionals in the city, Delivery of a personalized post-cancer plan
- Where
- France
- Volunteers
- 99 people
- Sponsor
- Centre Francois Baclesse
Head and Neck Cancer, Lung Cancer
Evaluation of a Cone-beam CT Scanner for Image Guided Radiotherapy
This is a feasibility study investigating the image quality of a new, high-performance cone beam CT (CBCT) used for on-couch imaging during radiotherapy treatments.
- Conditions
- Head and Neck Cancer, Lung Cancer, Breast Cancer, Abdominal Cancer
- Trial name
- CONFIGURE (NCT05524454)
- Testing
- Novel CBCT Imaging
- Where
- Netherlands
- Volunteers
- 41 people
- Sponsor
- Varian, a Siemens Healthineers Company
Bladder Cancer, Prostate Cancer
Medtronic Hugo™ Robotic Assisted Surgery (RAS) System in Urologic Surgery (Expand URO)
This study will evaluate the safety and performance of the Medtronic Hugo™ RAS System when used for urologic RAS procedures.
- Conditions
- Bladder Cancer, Prostate Cancer, Kidney Cancer, Pelvic Tumor
- Trial name
- NCT05696444
- Testing
- RAS Prostatectomy, RAS Cystectomy, RAS Nephrectomy
- Where
- 6 sites in United States
- Volunteers
- 144 people
- Sponsor
- Medtronic - MITG
Pelvic Pain
Impact of Thermotherapy During Childbirth on Postpartum Perineal Pain (PERISAFE)
Perineal pain is common after vaginal birth. Thermotherapy might be effective to limit postpartum perineal pain, thanks to the effects of local heating or cooling application.
- Trial name
- PERISAFE (NCT04778631)
- Testing
- Heat therapy, Cryotherapy
- Where
- 2 sites in France
- Volunteers
- 115 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Renal Pelvic Carcinoma, Tislelizumab
Nephron-sparing Treatment of Tislelizumab + Nab-Paclitaxel for Renal Pelvic Cancer
This study is designed as an open-label, single-arm, single-center, phase II clinical trial, aiming to evaluate the efficacy of nephron-sparing treatment combining Tislelizumab and Nab-Paclitaxel for HER-2 expressing renal pelvic…
- Conditions
- Renal Pelvic Carcinoma, Tislelizumab, PD-1 Inhibitor, Kidney-sparing
- Trial name
- NCT07233252
- Testing
- Nab-paclitaxel, Tislelizumab, endoscopic intervention
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Tianjin Medical University Second Hospital
Perinatal Solid Tumors of the Thoraco-abdomino-pelvic Region
Perinatal Thoraco-abdomino-pelvic Tumors Study
Congenital tumors are a rare diagnosis in the fetus and newborn. They differ from those of children and adults in terms of the nature, location and evolution of the tumor.
- Trial name
- CONTRAST (NCT06365268)
- Testing
- Collection of data from the patient's medical file
- Where
- 5 sites in France
- Volunteers
- 152 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thoracic Cancer, Head and Neck Cancer
SCINTIX [BgRT} Using RMRS in Solid and Soft Tissue Tumors
This study proposes 6 anatomic groupings which each can be defined similarly as the "head and neck" grouping above. These 6 groupings are: (1) Head and Neck, (2) Thoracic not including lung parenchymal, (3) Hepatobiliary and…
- Conditions
- Thoracic Cancer, Head and Neck Cancer, Pelvic Cancer, Hepatobiliary Carcinoma in Situ
- Trial name
- NCT06634706
- Testing
- RefleXion X1 Radiotherapy System [Imaging Only]
- Volunteers
- 96 people
- Sponsor
- RefleXion Medical
Cervical Cancer, Postoperative Bladder Dysfunction
Transcutaneous Electrical Nerve Stimulation in Nerve-Sparing Radical Hysterectomy: Effects on Bladder Management and Quality of Life in Cervical Cancer
To evaluate the effects of transcutaneous electrical nerve stimulation (TENS) on bladder management, pelvic floor muscle strength, and quality of life (QoL) in patients undergoing nerve-sparing radical hysterectomy (NSRH) for…
- Conditions
- Cervical Cancer, Postoperative Bladder Dysfunction, Urinary Retention, Pelvic Floor Muscle Weakness
- Trial name
- NCT07070687
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Fudan University
Cervical Cancer, Endometrial Cancer
Hypogastric Plexus Block and Ganglion Impar Block for Cervical and Endometrial Cancer Pain Management
This study compared the efficacy and safety of superior hypogastric plexus block and ganglion impar block procedures on the management of pelvic and perineal cancer pain in patients with cervical and endometrial cancer
- Trial name
- NCT05427058
- Testing
- Superior Hypogastric Plexus Block, Ganglion Impar Block
- Where
- Indonesia
- Volunteers
- 36 people
- Sponsor
- University of Brawijaya
Cervical Cancer, Uterine Cervical Neoplasm
Effect of an Anti-inflammatory Diet on Patients With Cervical Cancer
During radiation therapy (RT) to pelvic tumors, the small intestine, colon and rectum are inevitably included in the radiation field and are healthy tissues that suffer damage as an adverse effect.
- Conditions
- Cervical Cancer, Uterine Cervical Neoplasm, Pelvic Inflammatory Disease, Radiation Toxicity
- Trial name
- NCT03994055
- Testing
- Omega-3 fatty acids, Antioxidants, Soluble fiber
- Where
- Mexico
- Volunteers
- 136 people
- Sponsor
- National Institute of Cancerología
Pelvic Abscess, Adnexal Cyst
Ultrasound-guided Transvaginal Aspiration of Cystic Pelvic Lesions
Adnexal cysts or pseudocysts are a common finding on transvaginal ultrasound, especially in premenopausal women. Due to the size of some cysts, they may cause discomfort.
- Conditions
- Pelvic Abscess, Adnexal Cyst, Ovarian Neoplasms
- Trial name
- UTAC (NCT06988280)
- Testing
- Ultrasound-guided transvaginal aspiration of cystic pelvic lesions.
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cancer, Head and Neck Cancer
Phase IB Study Using Sunitinib Plus Radiation Therapy for Cancer Patients
This study is using the combination of radiation and antiangiogenic agents (agents that destroy existing blood vessels) seems to be an approach to tumor cure.
- Conditions
- Cancer, Head and Neck Cancer, Pelvic Cancer, Nervous System Neoplasms
- Trial name
- NCT00437372
- Testing
- Sunitinib, External Beam Radiation Therapy
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Vaginal Stenosis, Radiation Therapy
Feasibility of Hyivy Device Post-Radiation for Pelvic Malignancies
Vaginal dilator therapy (VDT) with static dilators is often prescribed to patients following vaginal or pelvic radiation therapy.
- Conditions
- Vaginal Stenosis, Radiation Therapy, Cancer, Pelvic Pain
- Trial name
- NCT05648253
- Testing
- Hyivy Intravaginal Device
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Hyivy Health Inc
Cervical Cancer Treated with Pelvic Radiotherapy, Cervical Cancers
Establishment and Validation of Prediction Model of Simultaneous Chemoradiotherapy for Cervical Cancer Organoids
This is a single-arm, single-center, open-label, Phase II study aimed at assessing the efficacy of organoids in predicting the response to radiotherapy and chemotherapy in cervical cancer
- Trial name
- ECCO (NCT06786780)
- Testing
- Drug: Cisplatin
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Chongqing University Cancer Hospital
Malignant Abdominal Neoplasm, Malignant Pelvic Neoplasm
Heated Intra-peritoneal Chemotherapy With Doxorubicin and Cisplatin for Abdominal for Pelvic Tumors in Pediatric Patients
This early phase I trial studies how well heated intra-peritoneal chemotherapy with doxorubicin and cisplatin work for the treatment of abdominal or pelvic tumors that can be removed by surgery (resectable), does not respond to…
- Conditions
- Malignant Abdominal Neoplasm, Malignant Pelvic Neoplasm, Recurrent Colon Carcinoma, Recurrent Desmoplastic Small Round Cell Tumor
- Trial name
- TOASTIT (NCT04213794)
- Testing
- Cisplatin, Cytoreductive Surgery, Doxorubicin
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic