Clinical trials: Pelvic Neoplasm
Adenocarcinoma of the Prostate
A Study of VEGF Tyrosine Kinase Inhibitor (Pazopanib) in Men With High-Risk Prostate Cancer Followed by Radical Prostatectomy and Pelvic Lymph Node Dissection
The area around a tumor ("pre-metastatic niche") may be an area to which cancer cells are attracted. The study doctor will take blood and tumor samples to look for certain features linked with response to treatment so that they…
- Trial name
- NCT01832259
- Testing
- Pazopanib
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Utah
Sexual Behavior, Pelvic Cancer
Sexuality of Women With Pelvic Cancer
This study aims to study in patients with cancer of the cervix or the body of the uterus, or the ovary between the time of diagnosis and 3 months after the end of the last treatment: the evolution of the relationship of couple…
- Trial name
- FECAPSE (NCT04070950)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Bordeaux
Colo-rectal Cancer
Psychological distREsS hipEc oR pelVic Exenteration
The purpose of this study is to describe type and extent of psychological distress (adverse effects) in patients undergoing surgery for colorectal cancer with peritoneal metastases and after surgery for colorectal cancer with…
- Trial name
- PRESERVE (NCT04956107)
- Where
- 3 sites in Denmark, Sweden
- Volunteers
- 225 people
- Sponsor
- University of Aarhus
Prostate Carcinoma
Brain and Pelvic Floor Muscle Activity of Patients Who Had or Are Undergoing Robot-Assisted Radical Prostatectomy
This trial investigates brain and pelvic floor muscle activity in patients undergoing robot-assisted radical prostatectomy. This trial may help identify the brain waves that are associated with muscles involved in giving patients…
- Trial name
- NCT04646434
- Testing
- Electroencephalography, Electromyography, Questionnaire Administration
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Roswell Park Cancer Institute
Rectal Cancer
Trial to Evaluate Laparoscopy-assisted Nerve-preserved Total Mesorectal Excision (LNTME) Versus Open TME for Rectal Cancer
The purpose of this study is to determine: (1) whether laparoscopy-assisted nerve-preserved total mesorectal excision (LNTME) is as safe as open TME for rectal cancer, and (2) whether LNTME is more effective for protection of…
- Trial name
- NCT02830633
- Testing
- LNTME, OTME
- Volunteers
- 80 people
- Sponsor
- Anhui Medical University
Anxiety
Surveillance Pelvic Examination Anxiety: Brief Coping Skills Intervention
The purpose of this study is to test the feasibility and acceptability of a brief coping skills training program addressing anxiety and pain related to surveillance pelvic examinations for female gynecologic cancer survivors.
- Trial name
- PEACE (NCT05285306)
- Testing
- PEACE Program
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Duke University
Endometrial Adenocarcinoma, Endometrial Adenosquamous Carcinoma
Comparison of Two Combination Chemotherapy Regimens Plus Radiation Therapy in Treating Patients With Stage III or Stage IV Endometrial Cancer
Randomized phase III trial to compare the effectiveness of two combination chemotherapy regimens plus radiation therapy in treating patients who have stage III or stage IV endometrial cancer.
- Conditions
- Endometrial Adenocarcinoma, Endometrial Adenosquamous Carcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Endometrioid Adenocarcinoma, Variant With Squamous Differentiation
- Trial name
- NCT00006011
- Testing
- Doxorubicin Hydrochloride, Cisplatin, Filgrastim
- Where
- United States
- Volunteers
- 659 people
- Sponsor
- Gynecologic Oncology Group
Cancer, Pelvic Floor Dysfunction
Pelvic Floor Dysfunction in Cancer Survivors.
Introduction: Pelvic floor dysfunctions (PFD) represent a major public health problem manifested through lower urinary tract symptoms (LUTS), anorectal and sexual dysfunction.
- Trial name
- NCT03979755
- Testing
- Application of questionnaires
- Where
- Brazil
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Bladder Small Cell Neuroendocrine Carcinoma, Bladder Squamous Cell Carcinoma
Cabozantinib S-malate and Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Genitourinary Tumors
This phase I trial studies the side effects and best doses of cabozantinib s-malate and nivolumab with or without ipilimumab in treating patients with genitourinary (genital and urinary organ) tumors that have spread from where…
- Conditions
- Bladder Small Cell Neuroendocrine Carcinoma, Bladder Squamous Cell Carcinoma, Bladder Urothelial Carcinoma, Clear Cell Renal Cell Carcinoma
- Trial name
- NCT02496208
- Testing
- Biopsy Procedure, Biospecimen Collection, Cabozantinib S-malate
- Where
- 8 sites in United States
- Volunteers
- 152 people
- Sponsor
- National Cancer Institute (NCI)
Urothelial Carcinoma, Ureteral Neoplasms
TRC105 in Adults With Advanced/Metastatic Urothelial Carcinoma
Background: Urothelial cancer (tumors of the bladder, urethra, ureter, or renal pelvis) often responds initially to standard chemotherapy treatments, but frequently recurs and can often spread to other parts of the body.
- Conditions
- Urothelial Carcinoma, Ureteral Neoplasms, Ureter Cancer, Neoplasm, Ureteral
- Trial name
- NCT01328574
- Testing
- TRC105
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- National Cancer Institute (NCI)
Hidden Blood Loss, Open Radical Hysterectomy
A Research on Hidden Blood Loss in Open Radical Hysterectomy and Pelvic Lymphadenectomy
The aim of this cross-sectional study is to evaluate the hidden blood loss in patients who underwent open radical hysterectomy and identity its risk factors.
- Conditions
- Hidden Blood Loss, Open Radical Hysterectomy, Cervical Cancer
- Trial name
- NCT03628118
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Rectal Cancer
VSL#3 Versus Placebo in Increasing the Pathological Major Response Rate in Patients With Rectal Cancer
This is a randomized, double-blind, placebo-controlled phase III study involving 160 patients designed to assess the efficacy of the high potency probiotic preparation VSL#3® versus placebo in increasing the pathological major…
- Trial name
- NCT01579591
- Testing
- VSL#3
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Catholic University of the Sacred Heart
Neoplasm Metastasis, Carcinoma
Helical Tomotherapy as a Radiotherapy Technique for Treating Pelvic and Abdominal Metastases
Radiation treatment is often used to treat cancer that has spread to the abdomen. It can be very effective at relieving symptoms such as pain, but the radiotherapy itself can cause side-effects such as cramping and diarrhea.
- Trial name
- NCT00129051
- Testing
- Tomotherapy
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alberta Health services
Rectal Cancer, Low Anterior Resection Syndrome
The Effects of Kegel Exercise Combined With Biofeedback Therapy on Bowel Function Recovery, Emotional Distress, and Quality of Life in Patients Following Low Anterior Resection for Rectal Cancer
This randomized controlled trial aims to evaluate the effects of combining Kegel exercise with a single biofeedback session on bowel function, emotional distress, and quality of life in patients who have undergone low anterior…
- Conditions
- Rectal Cancer, Low Anterior Resection Syndrome, LARS - Low Anterior Resection Syndrome
- Trial name
- BFT in LARS (NCT07253298)
- Testing
- Kegel Exercise with Biofeedback, Kegel Exercise Only
- Where
- Taiwan
- Volunteers
- 66 people
- Sponsor
- National Taiwan University Hospital
Bladder Carcinoma Infiltrating the Muscle of the Bladder Wall, Stage II Bladder Cancer AJCC v8
Avelumab in Combination With Fluorouracil and Mitomycin or Cisplatin and Radiation Therapy in Treating Participants With Muscle-Invasive Bladder Cancer
This phase II trial studies the side effects of avelumab and how well it works in combination with fluorouracil and mitomycin or cisplatin and radiation therapy in treating participants with muscle-invasive bladder cancer.
- Conditions
- Bladder Carcinoma Infiltrating the Muscle of the Bladder Wall, Stage II Bladder Cancer AJCC v8, Stage II Renal Pelvis Cancer AJCC v8, Stage II Ureter Cancer AJCC v8
- Trial name
- NCT03617913
- Testing
- Avelumab, Cisplatin, Fluorouracil
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Prostate Cancer, Postoperative Adhesion
The Effect of Guardix-solution for the Prevention of Postoperative Intestinal Adhesion and Intestinal Obstruction After Laparoscopic Pelvic Cavity Surgery
To assess the anti-adhesive effect of treatment with hyaluronic acid-carboxymethylcellulose following laparoscopic pelvic surgery (radical prostatectomy).
- Trial name
- NCT02773251
- Testing
- hyaluronic acid-carboxymethylcellulose
- Volunteers
- 60 people
- Sponsor
- Bucheon St. Mary's Hospital
Pelvic Gynecological Cancer
Preoperative Hypnosis in Gynecology
The research hypotheses that preoperative formal hypnosis session reduces perioperative anxiety among women undergoing a hysterectomy for pelvic gynecological cancer.
- Trial name
- HYPPOGYN (NCT03281018)
- Testing
- Caregiver Accompaniment Time (CAT) + preoperative hypnosis session
- Where
- France
- Volunteers
- 29 people
- Sponsor
- University Hospital, Bordeaux
Bladder Cancer, Carcinoma, Transitional Cell
Enzalutamide in Combination With Gemcitabine and Cisplatin in Bladder Cancer
The main purpose of this study is to find out the dose of enzalutamide that can be safely given with gemcitabine and cisplatin in patients with advanced bladder cancer.
- Conditions
- Bladder Cancer, Carcinoma, Transitional Cell, Renal Pelvis Cancer, Ureter Cancer
- Trial name
- NCT02300610
- Testing
- Enzalutamide, Cisplatin, Gemcitabine
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Uterine Cervical Neoplasm, Laparotomy
Different Surgical Approaches in Patients of Early-stage Cervical Cancer
This multi-center, randomized controlled study aims to compare the survival outcomes (including overall survival, progression-free survival and disease-free survival between Chinese uterine cervical patients receiving different…
- Conditions
- Uterine Cervical Neoplasm, Laparotomy, Laparoscopy, Survival
- Trial name
- NCT03739944
- Testing
- Laparotomic radical hysterectomy, Laparotomic radical trachelectomy, Laparoscopic radical hysterectomy
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Lei Li
Cancer, Diarrhea
Impact of Probiotics BIFILACT® on Diarrhea in Patients Treated With Pelvic Radiation
In this double-blinded randomized clinical trial study, investigators assessed probiotic used to prevent or delay radiation induced grade moderate to severe diarrhea with patient treated for pelvic cancer.
- Conditions
- Cancer, Diarrhea, Abdominal Pain, Quality of Life
- Trial name
- NCT01839721
- Testing
- Bifilact®
- Where
- Canada
- Volunteers
- 246 people
- Sponsor
- CHU de Quebec-Universite Laval