Clinical trials: Pelvic Neoplasms
Rectal Cancer
Chemotherapy Followed by Pelvic Reirradiation Versus Chemotherapy Alone as Pre-operative Treatment for Locally Recurrent Rectal Cancer
GRECCAR 15 is focused on Locally Recurrent Rectal Cancer (LRRC) for patients with previous pelvic radiotherapy for the primary rectal cancer.
- Trial name
- GRECCAR15 (NCT03879109)
- Testing
- Chemotherapy FOLFIRINOX, 6 cycles, Radiochemotherapy, Surgery
- Where
- 13 sites in France
- Volunteers
- 58 people
- Sponsor
- University Hospital, Bordeaux
Asymptomatic Bacteriuria in Subjects Not Requiring Assisted Bladder Emptying, Asymptomatic Bacteriuria in Subjects Relying on Some Type of Catheter
Effects of Microbiological and Immunological Factors on the Lower Urinary Tract
Millions of patients of all ages suffer worldwide from diverse urinary pathologies, such as lower urinary tract (LUT) dysfunction, bladder pain syndrome, urinary tract infections (UTIs), or bladder cancer.
- Conditions
- Asymptomatic Bacteriuria in Subjects Not Requiring Assisted Bladder Emptying, Asymptomatic Bacteriuria in Subjects Relying on Some Type of Catheter, Recurrent Non-catheter Associated UTIs, Acute Catheter-associated UTI (CAUTI)
- Trial name
- MiLUT (NCT07494864)
- Where
- Switzerland
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Long Term Cancer Side Effects, Supportive Care in Cancer
Optimize the Support of Patients in Pelvic Onco-gynecology Through Adapted Support Care in the Post-cancer Period. AFTERGYN Pilot Phase
While the sequelae and toxicities after ovarian and endometrial cancer treatments are well described in the literature, the actual needs of patients for supportive oncology care remain poorly documented.
- Conditions
- Long Term Cancer Side Effects, Supportive Care in Cancer, Cancer Survivorship Care Plan, Advanced Nurse Practitioner
- Trial name
- AFTERGYN (NCT05731661)
- Testing
- Day hospitalization in support care with meeting with support care professionals and coordination of actions by the advanced practice nurse, Delivery of useful information according to support care needs, concerning support care professionals in the city, Delivery of a personalized post-cancer plan
- Where
- France
- Volunteers
- 99 people
- Sponsor
- Centre Francois Baclesse
Cancer
MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma
RATIONALE: MS-275 may stop the growth of cancer cells by blocking the enzymes necessary for their growth. PURPOSE: This phase I trial is studying the side effects and best dose of MS-275 in treating patients with advanced solid…
- Trial name
- NCT00020579
- Testing
- entinostat
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter
Sunitinib in Treating Patients With Progressive Metastatic Transitional Cell Cancer of the Urothelium
RATIONALE: Sunitinib may stop the growth of tumor cells by blocking some of the enzymes needed for their growth and by blocking blood flow to the tumor.
- Conditions
- Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral Cancer
- Trial name
- NCT00397488
- Testing
- sunitinib malate
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Prostate Cancer
Stereotactic Ablative Radiotherapy (SABR) of Pelvis and Prostate Targets For High Risk Prostate Cancer
Since high risk prostate cancer requires higher radiation, this study is being done to determine the maximum tolerated dose of radiation to the prostate and pelvic regions.
- Trial name
- NCT02353819
- Testing
- Stereotactic Ablative Radiotherapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Texas Southwestern Medical Center
Cervical Cancer, Endometrial Cancer
Intensity-Modulated Radiation Therapy to the Pelvis With or Without Chemotherapy in Treating Patients With Endometrial Cancer or Cervical Cancer That Has Been Removed By Surgery
RATIONALE: Specialized radiation therapy (RT), such as intensity-modulated radiation therapy (IMRT), that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue.
- Trial name
- NCT00331760
- Testing
- cisplatin, intensity-modulated radiation therapy
- Where
- 153 sites in United States, Canada
- Volunteers
- 106 people
- Sponsor
- Radiation Therapy Oncology Group
Rectal Cancer, Neoplasm Metastasis
Study of Panitumumab Given First With Capecitabine and Oxaliplatin (CAPOX) and Then With Capecitabine and Radiation of the Pelvis for Treatment of Patients With Rectal Cancers That May or May Not Have Spread Beyond the Rectum
Panitumumab is a monoclonal antibody. It works by attaching to a protein called epidermal growth factor receptor found on normal and cancer cells.
- Trial name
- NCT00346099
- Testing
- Panitumumab with capecitabine and oxaliplatin (CAPOX) followed by, Panitumumab with capecitabine and radiation
- Sponsor
- NSABP Foundation Inc
Prostate Cancer, Bladder Cancer
Use of PET/MRI Tracer to Further Understanding of Prostate Cancer Development
The purpose of this study is to develop a novel technique for integrated PET/MRI tracer kinetic analysis for urologic malignancy.
- Trial name
- NCT02106416
- Testing
- PET/MRI
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Diarrhea, Gastrointestinal Complications
Sulfasalazine in Preventing Acute Diarrhea in Patients With Cancer Who Are Undergoing Pelvic Radiation Therapy
RATIONALE: Sulfasalazine may relieve diarrhea in patients with cancer who are undergoing pelvic radiation therapy. PURPOSE: This randomized phase III trial is studying sulfasalazine to see how well it works in preventing acute…
- Conditions
- Diarrhea, Gastrointestinal Complications, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT01198145
- Testing
- sulfasalazine
- Where
- 257 sites in United States
- Volunteers
- 87 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Cervical Cancer
Development & Validation of Utilities for Health States Relevant to Cervical Cancer Patients
Purposes of this study: 1) To define comprehensive set of descriptive health states related to treatment of cervical cancer (e.g.
- Trial name
- NCT00788216
- Testing
- Discussion & scoring of health states related to the treatment of cervical cancer
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duke University
Pelvic Neoplasms
Treatment of Hemorrhagic Radiation Proctitis Using the Halo System
This study involves evaluating a procedure in which the study device, the HALO90 Ablation catheter, is used to heat a thin layer of tissue lining the rectum using radiofrequency (RF) energy in subjects suffering from radiation…
- Trial name
- NCT01103492
- Testing
- HALO90 Ablation catheter
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Genitourinary Syndrome of Menopause (GSM), Breast Cancer Female
Genitourinary Syndrome of Menopause in Breast Cancer
This randomized, single-blind clinical trial will compare the effectiveness of multimodal pelvic floor physiotherapy (PPT) and fractional CO2 vaginal laser therapy in reducing genitourinary syndrome of menopause (GSM) symptoms…
- Trial name
- PILME (NCT06721936)
- Testing
- Multimodal pelviperineal physioterapy group, Laser CO2 Therapy group
- Where
- Spain
- Volunteers
- 182 people
- Sponsor
- University of Alcala
Cervical Carcinoma
Clinical Study of Indocyanine Green Displaying Pelvic Nerve in Radical Operation of Cervical Cancer
Indocyanine green was injected intravenously into patients with cervical cancer before operation. The nerve development was observed by infrared imaging system during operation, which was used as the basis for nerve preserving…
- Trial name
- NCT05087264
- Testing
- Indocyanine green
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Prostate Carcinoma
Brain and Pelvic Floor Muscle Activity of Patients Who Had or Are Undergoing Robot-Assisted Radical Prostatectomy
This trial investigates brain and pelvic floor muscle activity in patients undergoing robot-assisted radical prostatectomy. This trial may help identify the brain waves that are associated with muscles involved in giving patients…
- Trial name
- NCT04646434
- Testing
- Electroencephalography, Electromyography, Questionnaire Administration
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Roswell Park Cancer Institute
Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter
S0028, Gemcitabine and Paclitaxel in Treating Patients With Advanced or Recurrent Cancer of the Urinary Tract
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving more than one drug may kill more tumor cells.
- Conditions
- Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral Cancer
- Trial name
- NCT00022633
- Testing
- gemcitabine hydrochloride, paclitaxel
- Where
- 92 sites in United States
- Volunteers
- 65 people
- Sponsor
- SWOG Cancer Research Network
Myoma, Uterine Bleeding, Dysfunctional
Observation of Long-term Effects on Endometrium and Uterine Fibroids in Women With Ulipristal Acetate Therapy
A prospective observational study on italian women undergoing ulipristal acetate (uPa) therapy for symptomatic myomas and its impact on symptomatology and moreover on myomas architecture.
- Conditions
- Myoma, Uterine Bleeding, Dysfunctional, Uterine Bleeding Heavy, Dysmenorrhea
- Trial name
- NCT03972917
- Testing
- Transvaginal ultrasonographic examination
- Where
- Italy
- Volunteers
- 89 people
- Sponsor
- University of Campania Luigi Vanvitelli
Pain Cancer
Fluoroscopic Anterior Approach Versus Ultrasound Guided Superior Hypogastric Plexus Neurolysis in Cancer Pelvic Pain
Cancer related pelvic pain can be debilitating and difficult to treat. Superior hypogastric plexus neurolysis (SHPN) is considered to be an option for adequately relieving pain, with fewer side effects and improving the quality…
- Trial name
- NCT05299047
- Testing
- Group US-guided, Group fluoroscopy-guided
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Mansoura University
Polycystic Ovary Syndrome (PCOS), Menstrual Symptoms
Mindfulness-Based Education For Women With Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS), also known as polyendocrine metabolic ovarian syndrome (PMOS), is the most common endocrinologic disorder to affect women. Despite this, the disease's pathophysiology remains unclear.
- Conditions
- Polycystic Ovary Syndrome (PCOS), Menstrual Symptoms, Stress, Quality of Life
- Trial name
- NCT07718217
- Testing
- Mindfulness-Based Polycystic Ovary Syndrome (PCOS) Education
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Endometrial Cancer
Thunderbeat Technology vs Standard Bipolar Electro-surgery in Total Laparoscopic Hysterectomy With Pelvic Lymphadenectomy for Endometrial Cancer
This prospective randomized pilot study is aimed to verify if the operative time of a TLH with pelvic lymphadenectomy for endometrial cancer FIGO stage IB-II could be reduced using Thunderbeat (an ultrasonic energy device that…
- Trial name
- Thunder Endom (NCT01717794)
- Testing
- Thunderbeat technology, Standard bipolar electrosurgery
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Catholic University of the Sacred Heart