Clinical trials: Pelvic Neoplasms
Perioperative/Postoperative Complications, Prostate Cancer
Robotic Assisted Laparoscopic Prostatectomy With or Without Pelvic Drain Placement in Reducing Adverse Events After Surgery in Patients With Prostate Cancer
This randomized phase III trial studies robotic assisted laparoscopic prostatectomy (RALP) with pelvic drain placement to see how well it works compared to RALP without pelvic drain replacement in reducing adverse events after…
- Trial name
- NCT01613651
- Testing
- robot-assisted laparoscopic surgery, questionnaire administration, intraoperative complication management/prevention
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- City of Hope Medical Center
Anemia
Pilot Study of Epoetin Alfa for Patients Having Abdominal or Pelvic Surgery for Cancer
This pilot study is looking at how well epoetin alfa, given in the immediate post-operative period, works in reducing anemia and the need for transfusions.
- Trial name
- NCT00294203
- Testing
- Epoetin Alfa group
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Florida
Lung Neoplasm, Pelvic Neoplasm
Personalized Estimation of Doses Delivered During Image Guided Radiation Therapy Tests
In image-guided radiotherapy (IGRT), the repeated and increasingly intensive use of on-board positioning imaging, using 2D or 3D Mega-Volt (MV) or kilo-Volt (kV) imaging devices (cone-beam or CBCT scanners), is leading the…
- Conditions
- Lung Neoplasm, Pelvic Neoplasm, Breast Cancer, Cancer, Otorhinolaryngeal
- Trial name
- ELISA (NCT05258383)
- Testing
- 3D maps of physical doses
- Where
- 9 sites in France
- Volunteers
- 320 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Localized Prostate Carcinoma, Oligometastatic Prostate Carcinoma
Accuracy of 18F-rhPSMA-7.3 PET/ MRI for Prediction of Lymph Node Metastasis in Localized High-Risk Prostate Cancer
This clinical trial evaluates the use of an imaging scan (18F-rhPSMA-7.3 positron emission tomography [PET]/magnetic resonance imaging [MRI]) for identifying patients who are at risk of having their disease spread to the lymph…
- Conditions
- Localized Prostate Carcinoma, Oligometastatic Prostate Carcinoma, Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8
- Trial name
- NCT06389786
- Testing
- Bilateral Pelvic Lymph Node Dissection, Biospecimen Collection, Bone Scan
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Colorectal Cancer
Radiation Therapy, Surgery, and Chemotherapy in Treating Patients With Rectal Cancer That Can Be Surgically Removed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug, giving the drugs in different ways, and combining radiation therapy and surgery…
- Trial name
- NCT00002523
- Testing
- fluorouracil, leucovorin calcium, conventional surgery
- Where
- 35 sites in Belgium, France and 8 more
- Volunteers
- 1,011 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Urinary Incontinence
Improving Urinary Continence and Quality of Life in Prostate Cancer Patients
This intervention program combines biofeedback PFME with a telephone or support group intervention to treat persistent urinary incontinence (UI).
- Trial name
- NCT01365182
- Testing
- BF+SUPPORT, BF+PHONE
- Volunteers
- 279 people
- Sponsor
- Case Western Reserve University
Cervical Cancer, Lymph Node Metastasis
Development of an Imaging Prediction Model for Pelvic Lymph Node Metastasis of Cervical Cancer Using Artificial Intelligence Techniques.
This study is a retrospective exploratory trial conducted at a single center, aiming to develop and validate a preoperative lymphatic metastasis model for cervical cancer using artificial intelligence deep learning.
- Conditions
- Cervical Cancer, Lymph Node Metastasis, Artificial Intelligence
- Trial name
- NCT06448897
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Obstetrics & Gynecology Hospital of Fudan University
Cholecystitis, Endometriosis
Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery
This is a two period cross-over study randomizing patients undergoing laparoscopic surgery into 2 different groups: group 1 in which patients receive "deep neuromuscular blockade" in the beginning portion of their laparoscopic…
- Conditions
- Cholecystitis, Endometriosis, Bowel Obstruction, Fibroids
- Trial name
- NCT02812186
- Testing
- Deep to Moderate NMB, Moderate to Deep NMB, Rocuronium
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Stony Brook University
Bladder Cancer, Transitional Cell Bladder Cancer
A Phase II Study of AZD4877 (a Novel Anti-mitotic Agent) in Advanced Bladder Cancer
The purpose of this Phase II study is to determine if AZD4877, an experimental drug that is a novel anti-mitotic agent (Eg5 or Kinesin Spindle Protein inhibitor that interferes with tumor cell division leading to tumor growth)…
- Conditions
- Bladder Cancer, Transitional Cell Bladder Cancer, Urethra Cancer, Ureter Cancer
- Trial name
- NCT00661609
- Testing
- AZD4877
- Where
- 36 sites in United States, Canada and 3 more
- Volunteers
- 54 people
- Sponsor
- AstraZeneca
Uterine Fibroid, Uterine Bleeding
Can 3D Laparoscopy Improve Surgical Performances in Surgeons in Training?
Due to the inconclusive results on the benefits of 3D laparoscopic system present in literature, this prospective randomised pilot study aims to assess if the operative time of total laparoscopic hysterectomy (TLH) for benign…
- Conditions
- Uterine Fibroid, Uterine Bleeding, Uterine Prolapse
- Trial name
- NCT04209036
- Testing
- 0° 3D laparoscopy high-definition camera(Olympus Winter & IBE GMBH, Hamburg - Germany)
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- Catholic University of the Sacred Heart
Rectal Cancer
Protocol: Reconstruct the Pelvic Peritoneum Using BPF
Background: Extralevator abdominoperineal excision (ELAPE) may cause various surgical complications including disruption of perineal wound, perineal hernia and adhesive small-bowel obstruction.
- Trial name
- PPRBPF (NCT04177407)
- Testing
- Standard laparoscopic ELAPE with pelvic peritoneal floor reconstruction using bladder peritoneum flap are to performed.
- Where
- China
- Volunteers
- 30 people
- Sponsor
- West China Hospital
Locally Advanced Pelvic Cancer That Require Pelvic Exenteration
Laparoscopic Robot-assisted Pelvic Exenteration for Pelvic Primary and Recurrent Cancers
The Radium Hospital Oslo University Hospital Estimated date of first patient enrolled: 3rd quarter 2021 Anticipated recruitment period: 4 years Estimated date of last patient completed: 4th quarter 2025 Locally advanced pelvic…
- Trial name
- NCT05186493
- Testing
- robot-assisted total pelvic exenteration
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Prostate Cancer (Post Prostatectomy)
The Application of Somatosensory Interactive Pelvic Floor Muscle Training for Stress Urinary Incontinence in Men Underwent Radical Prostatectomy
The study aims to compare the efficacy of different pelvic floor muscle training (PFMT) modes on improving urinary incontinence (UI) recovery in prostate cancer (PCa) patients after radical prostatectomy (RP).
- Trial name
- NCT06740071
- Testing
- somatosensory interactive pelvic floor muscle training, pelvic floor magnetic stimulation therapy, standard pelvic floor muscle training
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Retroperitoneal Neoplasms
The Role of the Vascular Surgeon in Oncologic Surgery of Abdominal and Pelvic Retroperitoneal Masses
Retroperitoneal tumors (RPTs - retroperitoneal tumors) are neoplasms that originate from the soft tissues of the retroperitoneum and in their more invasive forms can involve the retroperitoneal organs and large abdominal and…
- Trial name
- IOVA-rpt (NCT06803251)
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Transitional Cell Carcinoma of Bladder, Urethra Cancer
A Study of ALT-801 in Combination With Cisplatin and Gemcitabine in Muscle Invasive or Metastatic Urothelial Cancer
This is a Phase Ib/II, open-label, multi-center, competitive enrollment and dose-escalation study of ALT-801 in a biochemotherapy regimen either containing cisplatin and gemcitabine or containing gemcitabine alone in patients who…
- Conditions
- Transitional Cell Carcinoma of Bladder, Urethra Cancer, Ureter Cancer, Malignant Tumor of Renal Pelvis
- Trial name
- NCT01326871
- Testing
- Cisplatin, Gemcitabine, ALT-801
- Where
- 16 sites in United States
- Volunteers
- 68 people
- Sponsor
- Altor BioScience
Prostate Cancer (Post Prostatectomy), Urinary Incontinence
Effects of Hypopressive Exercises on Urinary Incontinence and Erectile Dysfunction After Radical Prostatectomy
This randomized controlled trial investigates the effects of hypopressive exercises on urinary incontinence and erectile dysfunction in men following radical prostatectomy.
- Conditions
- Prostate Cancer (Post Prostatectomy), Urinary Incontinence, Erectile Dysfunction Following Radical Prostatectomy, Pelvic Floor Muscle Training
- Trial name
- NCT07101731
- Testing
- Pelvic Floor Muscle Training (PFMT), Hypopressive Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bartın Unıversity
Ovarian Neoplasms
Evaluation of Multiple Biomarkers to Estimate Risk of Ovarian Cancer in Patients With a Pelvic Mass.
ANGLE has developed the Parsortix™ Cell Separation System (Parsortix), an automated system capable of harvesting rare circulating cells for analysis from a sample of peripheral blood based on cellular size and deformability.
- Trial name
- NCT02785731
- Testing
- Pelvic imaging, Blood draw, laparotomy or laparoscopy
- Where
- 5 sites in Austria, Germany
- Volunteers
- 204 people
- Sponsor
- Angle plc
Cancer Metastatic, Trauma
IlluminOss Photodynamic Bone Stabilization System for the Treatment of Impending and Actual Pelvis Fractures
The aim of this project is to assess the effectiveness of the IlluminOss pelvic implants in patients with pelvic metastatic disease presenting with pain, risk of pathologic fracture, non-displaced or minimally displaced…
- Conditions
- Cancer Metastatic, Trauma, Pathologic Fracture
- Trial name
- NCT04842266
- Testing
- IlluminOss pelvic implant for oncologic indication, IlluminOss pelvic implant for geriatric trauma indication
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Urinary Incontinence, Prostate Cancer
Comparison of the Effectiveness of Different Conservative Treatment Protocols in Postprostatectomy Urinary Incontinence
The main purpose of this study is to reveal the effectiveness of the Knack maneuver and lifestyle recommendations program to be given in addition to the pelvic floor muscle training (PFMT) program, which has been proven to be…
- Conditions
- Urinary Incontinence, Prostate Cancer, Urinary Incontinence,Stress, Urinary Incontinence Due to Urethral Sphincter Incompetence
- Trial name
- NCT04804839
- Testing
- First research arm, Second research arm, Third research arm
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Hacettepe University
Prostate Cancer, Postoperative Adhesion
The Effect of Guardix-solution for the Prevention of Postoperative Intestinal Adhesion and Intestinal Obstruction After Laparoscopic Pelvic Cavity Surgery
To assess the anti-adhesive effect of treatment with hyaluronic acid-carboxymethylcellulose following laparoscopic pelvic surgery (radical prostatectomy).
- Trial name
- NCT02773251
- Testing
- hyaluronic acid-carboxymethylcellulose
- Volunteers
- 60 people
- Sponsor
- Bucheon St. Mary's Hospital