Clinical trials: Pelvic Prolapse
Rectal Prolapse
Intra-operative Adverse Events During Laparoscopic Ventral Mesh Rectopexy
Outcomes of laparoscopic ventral mesh rectopexy are well known, but data on intra-operative adverse events is scant. A multicenter pool-analysis of prospectively collected database on 1384 patients with internal/external rectal…
- Trial name
- NCT02870192
- Testing
- Laparoscopic ventral mesh rectopexy
- Volunteers
- 200 people
- Sponsor
- University of Rome Tor Vergata
Pelvic Organ Prolapse, Urinary Stress Incontinence
Advanced Genital Prolapse Surgery With and Without Mid Urethral Sling to Prevent Stress Urinary Incontinence
Pelvic organ prolapse (POP) is a public health problem worldwide, affecting about 30 %. It implies physical, psychological and social losses.
- Trial name
- NCT02578056
- Testing
- Midurethral sling, Genital prolapse surgery
- Where
- Brazil
- Volunteers
- 374 people
- Sponsor
- University of Sao Paulo General Hospital
Rectal Prolapse
Pathologic Assessment of Rectal Prolapse in the Young
Patients aging less than 45 years with rectal prolapse will undergo full pathologic and functional assessment to determine the underlying etiology.
- Trial name
- NCT03012464
- Testing
- Pathologic and functional assessment
- Where
- 2 sites in Egypt
- Volunteers
- 10 people
- Sponsor
- Mansoura University
Pelvic Floor Dysfunction
Evaluation of the Rectal Reflex Using Anal Acoustic Reflectometry
Anal Acoustic Reflectometry (AAR) is a reliable and reproducible technique that has been studied in our department over the last 6 years.
- Trial name
- NCT02782377
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Manchester University NHS Foundation Trust
Urinary Tract Infections, Urinary Retention Postoperative
Urinary Track Infection Prevention After Urogynecological Surgery
This study is randomized double-blinded placebo-controlled trial to access oral Methenamine Hippurate (MH) in combination with cranberry capsules is superior to cranberry capsules alone in prevention of UTI in patients with…
- Conditions
- Urinary Tract Infections, Urinary Retention Postoperative, Pelvic Organ Prolapse
- Trial name
- NCT03818321
- Testing
- Methenamine Hippurate 1 g tablet
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- TriHealth Inc.
Pelvic Organ Prolapse (POP), Postoperative Pain
Effect of Paracervical Block on Postoperative Pain After vNOTES Uterosacral Ligament Suspension
This study is a prospective, randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effect of paracervical block on early postoperative pain after vaginal natural orifice transluminal endoscopic…
- Trial name
- vNOTES-PB (NCT07440576)
- Testing
- Bupivacaine, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Erkan Gol
Pelvic Organ Prolapse (POP), Uterine Prolapse
Effectiveness of Laparoscopic Lateral Suspension With or Without Hysterectomy in Pelvic Organ Prolapse
This study aims to compare the effectiveness of laparoscopic lateral suspension (LLS) with and without hysterectomy in the treatment of pelvic organ prolapse.
- Trial name
- LLS-HYS (NCT07094815)
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people
- Sponsor
- Havva Betül Bacak
Pelvic Organ Prolapse
Can Pelvic Floor Muscle Training Reduce my Prolapse
Purpose The aim of this study is to examine if a structured pelvic floor muscle training combined with lifestyle advice with can improve pelvic organ prolapse (POP) symptoms more than structured lifestyle advice programme alone.
- Trial name
- NCT01612637
- Testing
- Pelvic floor muscle training and lifestyle advice, Lifestyle advice
- Where
- Denmark
- Volunteers
- 108 people
- Sponsor
- Copenhagen University Hospital at Herlev
Pelvic Organ Prolapse, Normal Pelvic Floor
The 3D Reconstruction Research of Pelvic Organ Prolapse Disease
Female pelvic organ prolapse (FPOP) is one of the main diseases affecting the quality of life of middle aged and elderly women in non-neoplastic diseases.
- Trial name
- NCT03146195
- Testing
- Dynamic Magnetic resonance imaging
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Pelvic Floor Prolapse
The Effect of Intra-vaginal Conjugated Estrogen Cream on Ring Pessary Use for Pelvic Organ Prolapse
The primary purpose of this two-arm randomized clinical trial is to determine if in women desiring use of a pessary for pelvic organ prolapse (POP) and are successfully fit, if 1-year use and patient impression of improvement is…
- Trial name
- NCT04393194
- Testing
- Vaginal Cream with Applicator [Dose Form]
- Volunteers
- 420 people
- Sponsor
- Peking Union Medical College Hospital
Prolapse; Female
Barbed-suture Efficiency Study for Sacrocolpopexy
Minimally invasive sacrocolpopexy (SCP) performed laparoscopically or with robotic assistance is associated with improved patient-centered outcomes such as faster recovery times, less pain, less bleeding, and shorter hospital…
- Trial name
- BEST (NCT05760794)
- Testing
- Non-barbed delayed absorbable suture, Barbed delayed absorbable suture
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Wake Forest University Health Sciences
Disability Physical, Urinary Incontinence
Transversus Abdominis and Pelvic Floor Muscle Strengthening Exercise Program In Patients With Grade 1 Cystocele
Cystocele, a protrusion of the bladder, happens while the bladder descends into the vagina. There are more than one underlying causes for the development of cystocele ensuing in weak point of the muscles and the connective tissue…
- Conditions
- Disability Physical, Urinary Incontinence, Prolapse
- Trial name
- NCT05474495
- Testing
- Pelvic floor muscle training, Transverse abdominas strength training
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Pelvic Organ Prolapse
Lateral Suspension and Sacropexy for Pelvic Organ Prolapse
Pelvic organ prolapse (POP) is considered one of the commonest gynecologic health problems all over the world. Pelvic organ prolapse (POP) is common and can be seen in up to 50% or more of parous women.
- Trial name
- NCT03772691
- Testing
- lateral suspension, sacropexy
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Assiut University
Pelvic Organ Prolapse, Uterovaginal Prolapse
Absorbable Suture vs Permanent Suture in Sacrospinous Ligament Suspension
Sacrospinous ligament suspension (SSLS) was first described in 1958. It is commonly performed for correction of apical prolapse. A combination of delayed absorbable and/or permanent sutures are commonly used for the procedure.
- Conditions
- Pelvic Organ Prolapse, Uterovaginal Prolapse, Vaginal Vault Prolapse, Cystocele
- Trial name
- NCT05688059
- Testing
- Absorbable Suture and Permanent Suture
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Atlantic Health System
Pelvic Organ Prolapse
Performance of Tension Free Vaginal Mesh (Prolift) Versus Conventional Vaginal Prolapse Surgery in Recurrent Prolapse.
Pelvic organ prolapse is a common problem. A lot of women have surgery for prolapse. The recurrence rate op pelvic organ prolapse after surgical treatment is high.
- Trial name
- NCT00372190
- Testing
- Tensionfree vaginal mesh kit (Prolift), classic vaginal prolapse surgery (fascia plication)
- Where
- 13 sites in Netherlands
- Volunteers
- 194 people
- Sponsor
- Radboud University Medical Center
Vaginal Vault Prolapse
Restorelle® Y Mesh vs. Vertessa® Lite Y Mesh for Laparoscopic and Robotic-assisted Laparoscopic Sacrocolpopexy
This is a randomized clinical trial to compare outcomes between the Restorelle® Y mesh and Vertessa® lite Y mesh for the treatment of vaginal vault prolapse.
- Trial name
- Lite-Y (NCT03681223)
- Testing
- Vertessa® Lite Y mesh, Restorelle® Y mesh, Laparoscopic sacrocolpopexy
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- The Cleveland Clinic
Stress Urinary Incontinence, Pelvic Organ Prolapse
Pelvic Floor Muscles and Success in the Surgical Treatment of Stress Urinary Incontinence and Pelvic Organ Prolapse
The aim of the study is evaluation of the efficiency of pelvic floor muscles in the context of surgical outcomes in the treatment of stress urinary incontinence and pelvic organ prolapse.
- Conditions
- Stress Urinary Incontinence, Pelvic Organ Prolapse, Pelvic Floor Disorders
- Trial name
- NCT04029168
- Where
- Poland
- Volunteers
- 140 people
- Sponsor
- Żelazna Medical Centre, LLC
Pelvic Organ Prolapse
Prospective Performance Analysis of the Exair(TM) Prolapse Repair System in the Treatment of Pelvic Organ Prolapse
The aim of the study was to assess the role of the Exair transvaginal mesh system to correct pelvic organ prolapse from a subjective and objective standpoint.
- Trial name
- NCT03271294
- Testing
- Exair Transvaginal Mesh
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Michigan Institution of Women's Health PC
Cystocele
A Novel Suturing Technique of Cystocele Treatment
The rug weaving-like plication technique may offer a viable alternative for cystocele repair without mesh, utilizing natural tissue.
- Trial name
- cystosel (NCT06410469)
- Testing
- rug weaving-like plication technique
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Ankara City Hospital Bilkent
Vaginal Vault Prolapse
Prospective Study for Vaginal Vault Prolapse After Hysterectomy: Comparison of Two Surgical Methods
The study is carried out at the Sahlgrenska University Hospital and the patient population consists of women referred with symptomatic and bothersome post-hysterectomy vaginal vault prolapse at least 1 cm above or beyond the…
- Trial name
- NCT02290288
- Testing
- vaginal surgery, laparoscopic surgery
- Where
- Sweden
- Volunteers
- 138 people
- Sponsor
- Sahlgrenska University Hospital