Clinical trials: Pelvic Prolapse
Vaginal Prolapse
Observational Data Collection of Surgical Outcomes in the Treatment of Vaginal Prolapse With AMS Products
This registry was observational (only collected information typically noted by the surgeon when their patients were routinely seen); there was no change to the care the patient received as a result of being part of the registry).
- Trial name
- POWER1012 (NCT00388947)
- Testing
- AMS Prolapse Product
- Where
- United States
- Volunteers
- 1,543 people
- Sponsor
- ASTORA Women's Health
Pelvic Organ Prolapse
Pelvic Ultrasound Pessary Study: Changes in Pelvic Anatomy After Placing a Pessary
In the past, the impact of pessaries was mostly assessed by questionnaires on Quality of Life (QoL) and sexual dysfunction. This research project primarily aims to objectify the effects of the currently available pessaries in a…
- Trial name
- PUPS (NCT04915664)
- Testing
- Pessary
- Where
- Belgium
- Volunteers
- 269 people
- Sponsor
- Universiteit Antwerpen
Abnormal Uterine Bleeding, Endometriosis
Performance of SYMMCORA® vs. V-Loc® Suture Material in Patients Undergoing Laparoscopic Total Hysterectomy
The aim of this study is to show the superiority of the new unidirectional barbed suture (SYMMCORA® mid-term, unidirectional) to conventional suture material in terms of time to perform the vaginal cuff closure during gynecologic…
- Conditions
- Abnormal Uterine Bleeding, Endometriosis, Uterine Prolapse, Uterine Cancer
- Trial name
- BARHYSTER (NCT06024109)
- Testing
- Closure of the Vaginal Cuff after Total Hysterectomy
- Where
- 2 sites in Germany, Spain
- Volunteers
- 132 people
- Sponsor
- Aesculap AG
Pelvic Organ Prolapse, Prolapse Uterus
Combination of Laparoskopic Uterosacral Ligament and Round Ligament Plication, A Meshless Method in the Surgical Treatment of Pelvic Organ Prolapse.
Postoperative Results of a Meshless Method in the Surgical Treatment of Pelvic Organ Prolapse; Combination of Laparoscopic Uterosacral Ligament and Round Ligament Plication.
- Conditions
- Pelvic Organ Prolapse, Prolapse Uterus, Prolapse Bladder
- Trial name
- NCT04894032
- Testing
- Combination of Laparoscopic Uterosacral Ligament and Round Ligament Plication.
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Pelvic Organ Prolapse, Abdominal Surgery
The Effect of Abdominal Binder Use on Postoperative Pain and Mobility in Patients Undergoing Pelvic Surgery
To determine the effect of post-operative abdominal binder usage on total narcotic usage after undergoing surgery. To determine if abdominal binder usage results in decreased visual analog scale (VAS) pain scores and shorter time…
- Conditions
- Pelvic Organ Prolapse, Abdominal Surgery, Laparoscopic Surgery, Post Operative Pain
- Trial name
- NCT03684304
- Testing
- Abdominal binder
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Pelvic Organ Prolapse
Advanced Biomarker Assessment in Pelvic Organ Prolapse
This study will assess advanced biomarkers in patients with and without vaginal prolapse. Assessments will be directed at vaginal fibroblasts and adipose derived stem cells.
- Trial name
- NCT03642054
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Mayo Clinic
Pelvic Floor Disorders, Obstetric Trauma
Correlation Pelvic Floor Function and Ultrasound Findings One Year After Childbirth
This is a single-center prospective cohort study sponsored by the University Hospitals Leuven (UZ). Women will undergo a pelvic floor ultrasound and will be asked to fill out a questionnaire at the time of their admission into…
- Conditions
- Pelvic Floor Disorders, Obstetric Trauma, Urinary Incontinence, Anal Incontinence
- Trial name
- DeliverUU (NCT05530681)
- Testing
- Questionnaire, Pelvic floor ultrasound
- Where
- Belgium
- Volunteers
- 320 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pelvic Organ Prolapse
Risk Factors for Co-existence of Cervical Elongation in Uterine Prolapse
The presence of co-existence of cervical elongation in women of uterine prolapse may decrease the patients' satisfaction of uterine-preservation surgery for uterine prolapse, and additional surgery, such as Manchester surgery…
- Trial name
- NCT02465658
- Testing
- Medical records were reviewed.
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Vaginal Hysterectomy, Pelvic Organ Prolapse Vaginal Surgery
The Effect of Physiotherapy Treatment Following Gynaecological Surgery
Optimal pelvic floor muscle function is known to assist bladder and bowel function and control, pelvic organ support, as well as other areas of health.
- Trial name
- NCT00222326
- Testing
- Pelvic floor muscle training and lifestyle modification
- Where
- Australia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Pelvic Floor Prolapse
Treatment of Pelvic Organ Prolapse by PIVS Versus Surgeon Cut Mesh
Women with pelvic floor prolapse who underwent surgery with mesh will be enrolled. The investigators will compare data from the chart, telephone interviews and physical examinations between those who underwent mesh placement to…
- Trial name
- NCT01387685
- Where
- 2 sites in Israel
- Sponsor
- Western Galilee Hospital-Nahariya
Pelvic Organ Prolapse Vaginal Surgery, Stress Urinary Incontinence in Women
The AMPER Study: Evaluation of the Efficacy of Human Amniotic Membrane Grafting in Preventing Mesh Exposure in Vaginal Reconstructive Surgery Using Polypropylene Mesh.
This study evaluates the efficacy of adding a human amniotic membrane graft to polypropylene mesh surgery for pelvic prolapse and stress urinary incontinence.
- Trial name
- AMPER (NCT07414849)
- Testing
- Sacrospinous Hysteropexy with Mesh, Retropubic Mid-urethral Sling (Bottom-Up), Transobturator Mid-urethral Sling (Out-In)
- Where
- Argentina
- Volunteers
- 330 people
- Sponsor
- Hospital General de Agudos J. M. Penna
Pelvic Organ Prolapse
Anatomical and Functional Outcomes of Perigee and Apogee Mesh in Total Pelvic Floor Reconstruction Versus Gynecare Prolift
The investigators designed a prospective study in this article to evaluate the efficacy, the life quality and the complications of two different meshes of type I (one is Perigee/Apogee, the other is named Gynecare prolift) versus…
- Trial name
- mesh (NCT03070873)
- Testing
- Perigee and Apogee Mesh, Gynecare Prolift Mesh, Traditional Surgery
- Volunteers
- 258 people
- Sponsor
- Nanjing Medical University
Pelvic Organ Prolapse, Vaginal Prolapse
Cross-Shaped Vaginal Pessary for Pelvic Organ Prolapse
This prospective multicenter single-arm study evaluates the effectiveness and safety of a novel volumetric cross-shaped vaginal pessary in women with pelvic organ prolapse who had prior experience using a traditional vaginal…
- Trial name
- CROSS-PES (NCT07554651)
- Testing
- Volumetric Cross-Shaped Vaginal Pessary
- Where
- 5 sites in Ukraine
- Volunteers
- 51 people
- Sponsor
- Dnipro State Medical University
Anaemia Postoperative
Clinical Utility of Postoperative Hemoglobin Testing
The purpose of this study is to evaluate how many patients have hemoglobin less than 10 g/dL at post-operative day 1
- Trial name
- NCT04170764
- Where
- United States
- Volunteers
- 664 people
- Sponsor
- TriHealth Inc.
Pelvic Organ Prolapse, Cystocele
Native Tissue Repair in Pelvic Organ Prolapse -Long-term Results and Risk of Re-operation
This study evaluates the recurrence of pelvic organ prolapse and the rate of re-operation after primary surgery for anterior vaginal wall prolapse with native tissue repair in long term follow-up.
- Trial name
- NCT06744972
- Volunteers
- 392 people
- Sponsor
- Turku University Hospital
Pelvic Organ Prolapse
Lateral Suspension Versus Sacral Colpopexy POP
The aim of the study will be to compare the SCP and LLS in the management of apical prolapse at 6 weeks, 6 months, 1 year and yearly up to 2 years with the null hypothesis being that no significant differences existed between the…
- Trial name
- LLS vs SCP (NCT03644628)
- Testing
- Laparoscopic repair of anterior and apical pelvic organ prolapse
- Volunteers
- 200 people
- Sponsor
- Medical University of Vienna
Postoperative Complications
Comparison Between Two Types of Meshes Used in Pelvic Organs Prolapse Procedures
Using partially absorbed meshes in pelvic reconstructive surgery will involve fewer postoperative complications especially less pain caused by the mesh mass.
- Trial name
- NCT01645020
- Where
- Israel
- Volunteers
- 240 people
- Sponsor
- Western Galilee Hospital-Nahariya
Uterine Prolapse
Combined Effects of Pelvic Floor Retraining and Hypopressive Exercises in Uterine Prolapse Outcomes
One common pelvic floor condition, particularly in postpartum or later life, is uterine prolapse. It is caused by weak pelvic floor muscles and connective tissues and often presents with pain, urinary incontinence, and reduced…
- Trial name
- NCT07642180
- Testing
- Functional Movement Retraining + Hypopressive Exercises, Pelvic Floor Functional Movement Retraining
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Pelvic Organ Prolapse
Impact of Female Pelvic Reconstruction Surgery on Lower Urinary Tract Symptoms, Psychosomatic Distress and Sexual Function
To get the impact of pelvic floor reconstruction surgery on lower urinary tract symptoms, psychological distress and sexual function.
- Trial name
- NCT04416152
- Testing
- Pelvic reconstruction surgery
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Far Eastern Memorial Hospital
Pelvic Organ Prolapse (POP)
Restorelle Direct Fix Anterior and Posterior (A&P) for Female Pelvic Organ Prolapse: A Prospective Post Market Study
This is a prospective, multi-center study designed to assess the palpability of the Restorelle Direct Fix A\&P mesh after vaginal reconstruction surgery.
- Trial name
- (A&P) (NCT01378065)
- Testing
- Restorelle Direct Fix A&P
- Where
- 6 sites in United States
- Volunteers
- 31 people
- Sponsor
- Coloplast A/S