Clinical trials: Pelvic Prolapse
Rectal Prolapse
Comparison of Sclerotherapy Agents Used for Rectal Prolapse Treatment in Children
Introduction Patients with rectal prolapse are treated with injection sclerotherapy, which is the most often used first-line surgical technique.
- Trial name
- Prolapse (NCT06353230)
- Testing
- injection 5% phenol in almond oil, injection 15% hypertonic saline, injection 50% dextrose water
- Where
- Pakistan
- Volunteers
- 93 people
- Sponsor
- King Edward Medical University
Pelvic Floor Disorders
Pelvic Floor Function Evaluation of Singleton Primiparae After Vaginal Delivery and Cesarean Section
Objective of this longitudinal observational cohort study was to analyze incidence of pelvic floor dysfunction (PFD) symptoms, including pelvic organ prolapse (POP), urinary incontinence (UI), and fecal incontinence (FI), seven…
- Trial name
- NCT02661867
- Testing
- delivery
- Volunteers
- 865 people
- Sponsor
- Brno University Hospital
Pelvic Organ Prolapse
Healing Statements and Their Effect on Post Operative Pain
This is a randomized clinical trial comparing the severity of post-operative pain and use of pain medication in women who are and are not exposed to healing statements before undergoing vaginal hysterectomy with minimally…
- Trial name
- PHSPOPC (NCT02502357)
- Testing
- Healing Statements
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Medstar Health Research Institute
Pelvic Organ Prolapse, Pelvic Floor Disorders
Effect of Local Estriol Treatment Before Vaginal Repair Surgery
The aim of the study is to evaluate the effects of local estriol treatment applied before vaginal repair surgery on steroid receptors, inflammatory cell response, vascular, connective and nervous tissues in the vagina, and its…
- Conditions
- Pelvic Organ Prolapse, Pelvic Floor Disorders, Menopause, Vaginal Atrophy
- Trial name
- NCT06391372
- Testing
- estriol cream
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Hatice Tukenmez Kurnaz
Urinary Incontinence, Pelvic Organ Prolapse
Promoting Effective Recovery From Labor Urinary Incontinence (PERL)
The purpose of this study is to determine whether pushing during labor that is controlled by the woman results in less birth-related injury and less postpartum urinary incontinence (UI).
- Conditions
- Urinary Incontinence, Pelvic Organ Prolapse, Perinatal Laceration, Second Stage Labor
- Trial name
- PERL (NCT00506116)
- Testing
- Videotape, routine care, PME instruction, PME practice and record keeping (in diaries), Non-directed or directed,spontaneous or sustained pushing
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pelvic Organ Prolapse
Sacro-Spinous Ligaments Anterior Apical Anchoring
Anterior-apical compartment mesh implants for pelvic floor reconstruction are anchored here to the Sacro-Spinous ligaments and evaluated being a feasible and effective method.
- Trial name
- NCT01842464
- Testing
- Anterior Sacro-Spinous
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Pelvic Organ Prolapse
Composite Graft Use in Abdominal Sacrocolpopexy Reduces Erosion Rates
This study is to determine whether the use of a composite biologic/synthetic graft during abdominal sacrocolpopexy leads to a lower rate of erosion while maintaining durability.
- Trial name
- NCT00581412
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Irvine
Cystocele
Vaginal Mesh Procedures for Female Cystocele
This study aimed to evaluate primarily the functional outcomes and secondly the morphological outcomes for women who had received standard managements for cystocele at mediate-term follow-up.
- Trial name
- NCT04481906
- Testing
- Vaginal mesh for female cystocele
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cathay General Hospital
Endometriosis, Pelvic Prolapse
Suspension of the Pelvic and Abdominal Organs During Minimally Invasive Surgery
The goal of this retrospective observational study is to evaluate the efficacy, safety, and practicality of an organ suspension technique with adjustable tension suture in facilitating minimally invasive gynecologic surgeries at…
- Conditions
- Endometriosis, Pelvic Prolapse, Endometrium Cancer
- Trial name
- NCT06187558
- Testing
- Pelvic and abdominal organ suspension technique
- Where
- Italy
- Volunteers
- 330 people
- Sponsor
- University of Cagliari
Pelvic Organ Prolapse, Postoperative Pain
Does the Use of Bupivacaine Soaked Vaginal Packing Following Vaginal Surgery Decrease Postoperative Pain?
In current practice, packing in the vagina overnight after vaginal surgery is typically used to prevent post-surgical vaginal bleeding.
- Trial name
- NCT03266926
- Testing
- Bupivacaine, Premarin Vaginal cream
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Uterine Prolapse
Does Doing Pelvic Floor Exercise Ease Symptoms for Women Living With Prolapse?
The purpose of this study is to investigate the feasibility of undertaking a multi-centre randomised controlled trial of the effectiveness of a pelvic floor muscle training (PFMT) intervention for women with pelvic organ prolapse.
- Trial name
- NCT00158626
- Testing
- pelvic floor muscle training
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- Glasgow Caledonian University
Vaginal Prolapse
Using a Sheathed Speculum to Visualize and Access the Cervix In Women With Excessive Vaginal Tissue
The main objective of the study is to assess the effectiveness of the sheathed speculum in providing adequate visualization and access to the cervix in patients with excessive vaginal tissue.
- Trial name
- NCT01409902
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Pelvic Organ Prolapse
Patient Educational Video for Pelvic Organ Prolapse
This is a single-blinded, randomized controlled trial investigating if a patient educational video on pelvic organ prolapse improves patient understanding of this pelvic floor disorder and satisfaction in their healthcare…
- Trial name
- NCT04996563
- Testing
- Video
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Pelvic Organ Prolapse
Pelvic Floor Muscle Training and Hypopressive Exercises for Pelvic Organ Prolapse
To verify if pelvic floor muscle training program and/or a hypopressive exercise program could improve women with stage II of pelvic organ prolapse, their symptoms or pelvic floor muscle strength.
- Trial name
- NCT01196598
- Testing
- Exercises
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Federal University of São Paulo
Pelvic Organ Prolapse
Evaluation of Neuromuscular Morphometry of the Vaginal Wall
In this prospective study, women aged between 40 and 75 years who had not undergone any vaginal surgery and had not undergone any abdominal prolapse surgery were included.
- Trial name
- NCT06363838
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Uterine Prolapse
Laparoscopic Surgery in Elderly Patients
The primary purpose is to evaluate the quality of post-operative recovery and post-operative pain in elderly patients (more than 75 years) who undergo laparoscopic surgery for uterine prolapse.
- Trial name
- NCT03095716
- Testing
- laparoscopic surgery
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pelvic Organ Prolapse, Rectocele
Impact of Defecation Posture on Ease of Bowel Movements in Patients With a Rectocele
The study aims to determine if defecation posture, when using a defecation posture modification device (DPMD), will improve ease of bowel movements in patients with pelvic organ prolapse, specifically rectoceles.
- Conditions
- Pelvic Organ Prolapse, Rectocele, Bowel Dysfunction
- Trial name
- NCT06252714
- Testing
- Defecation Posture Modification Device
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- TriHealth Inc.
Pelvic Organ Prolapse
Pain After Insufflation for Robotic Sacrocolpopexy (PAIRS) Trial
This study evaluates post-operative pain between different insufflation pressures during robotic-assisted sacrocolpopexy. Subjective pain and narcotic usage after surgery will be measured.
- Trial name
- NCT04858438
- Testing
- Insufflation during surgery
- Where
- United States
- Sponsor
- Henry Ford Health System
Pelvic Organ Prolapse
The Follow-up of Mesh/Native Tissue Complications Study(Part II)
To study the incidence and distribution of complications after different pelvic reconstruction surgeries (mesh/native tissue) in multi-centers.
- Trial name
- NCT03617211
- Where
- 5 sites in China
- Volunteers
- 1,530 people
- Sponsor
- Peking Union Medical College Hospital
Pelvic Organ Prolapse
A Pilot Study to Investigate the Efficacy of Partially Absorbable Mesh in Patients With Pelvic Organ Prolapsed
The purpose of this study is to evaluate the efficacy, recurrence, postoperative complications of partially absorbable mesh(Seratom®PA) in patients with pelvic organ prolapse.
- Trial name
- NCT02320643
- Testing
- Seratom® PA mesh
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samyang Biopharmaceuticals Corporation