Clinical trials: Pelvic Prolapse
Pelvic Organ Prolapse
3D Translabial Ultrasound for Pessary Size Estimation
This is a feasibility study looking at the use of 3D ultrasound with vaginal manometry at various distension volumes to predict the best available pessary for successful fit.
- Trial name
- NCT03955744
- Testing
- 3D translabial ultrasound
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Western University, Canada
Pelvic Floor Disorders, Prolapse; Female
Effects of the Hypopressive Exercises in Women With Pelvic Organ Prolapse
The aim of this study was compare home-based pelvic floor muscle training (PFMT) alone and home-based PFMT combined with hypopressive exercise (HE) in terms of pelvic floor muscle (PFM) activation and severity of pelvic floor…
- Trial name
- NCT06352112
- Testing
- Pelvic Floor Muscle Training, Hypopressive Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Hacettepe University
Pelvic Organ Prolapse
Video Decision Aid in Latina Women With Pelvic Organ Prolapse
Pelvic organ prolapse (POP) is a highly prevalent condition among women that impairs quality of life, daily activities and sexual function.
- Trial name
- NCT02850835
- Testing
- Video Decision Aid
- Volunteers
- 33 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Pelvic Organ Prolapse
Different Types of Suture for Sacral Colpopexy
This randomized controlled study is designed to test absorbable suture compared to non absorbable suture in laparoscopic sacral colpopexy in terms of anatomical correction of the prolapse, post-operative and long term morbidity…
- Trial name
- NCT03582410
- Testing
- laparoscopic sacral colpopexy with absorbable suture, laparoscopic sacral colpopexy with non absorbable suture
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Catholic University of the Sacred Heart
Prolapse
Surgical Study Comparing 2 Procedures for the Treatment of a Dropped Bladder
The purpose of this study is to determine whether vaginal repair or abdominal repair is the procedure of choice for the surgical management of a prolapsed bladder.
- Trial name
- NCT00271102
- Testing
- anterior vaginal repair (colporrhaphy), abdominal paravaginal defect repair
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Geisinger Clinic
Voiding Dysfunction
Evaluating the Optimal Volume Voided for Passage of a Backfill-Assisted Voiding Trial Following Urogynecologic Surgery
Urinary retention can lead to bladder over-distention, ischemia, and long-term voiding dysfunction, and early identification of urinary retention can help prevent these adverse events
- Trial name
- NCT05820139
- Testing
- Control Group, Test Group
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wake Forest University Health Sciences
Pelvic Organ Prolapse
Uterosacral Ligament Suspension vs Robotic Sacrocolpopexy
This cross sectional, two cohort study seeks to investigate both anatomic outcome and subjective, functional outcome of uterosacral ligament suspension versus robotic sacrocolpopexy and compare patient satisfaction, bladder…
- Trial name
- NCT02741830
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- TriHealth Inc.
Rectal Prolapse
Comparative Study Between Delorme Operation With or Without Postanal Repair in Treatment of Complete Rectal Prolapse
The aim of the study is to compare Delorme operation alone or with post anal repair and levatorplasty for treating complete rectal prolapse.consecutive patients who were treated for complete rectal prolapse at the Colorectal…
- Trial name
- NCT01656369
- Testing
- Group I: delorme operation only., delorme operation with post anal repair
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Mansoura University
Hysterectomy, Sacrocolpopexy
Permanent Versus Delayed-Absorbable Monofilament Suture
This is an extension study of a prospective, multicenter, randomized, single-blind trial whose purpose is to compare mesh-related complications and effectiveness of pelvic organ prolapse (POP) repair in women undergoing…
- Trial name
- E-PACT (NCT04506177)
- Where
- 5 sites in United States
- Volunteers
- 200 people
- Sponsor
- Wake Forest University Health Sciences
Urinary Bladder, Overactive, Pelvic Organ Prolapse
Study of Overactive Bladder in Women With Prolapse
Pelvic organ prolapse (POP) is a common problem. Symptoms of overactive bladder (OAB) are present in approximately 50% of patients with POP.
- Trial name
- SOAP (NCT01540214)
- Testing
- Pre- and postoperative evaluations
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Radboud University Medical Center
Pelvic Organ Prolapse
Testing a Decision Aid for Women With Urogenital Prolapse
Development of a decision aid for women with urogenital prolapse followed by an intervention with use of the decision aid to investigate the effect on the perceived shared decision making in the clinical consultations.
- Trial name
- NCT03706716
- Testing
- decision aid developed for pelvic organ prolapse
- Where
- 3 sites in Denmark
- Volunteers
- 82 people
- Sponsor
- University of Southern Denmark
Pelvic Organ Prolapse
Long-term Evaluation of the Efficacy and Safety of Splentis for the Treatment of Primary Apical Pelvic Organ Prolapse
This prospective, multi center cohort trial aims to evaluate the efficacy and safety of hysteropexy using Splentis via the vaginal route in primary uterine prolapse
- Trial name
- SAXO (NCT05042453)
- Testing
- Splentis® POP Tissue Anchoring System
- Where
- 7 sites in Germany
- Volunteers
- 140 people
- Sponsor
- Promedon
Pelvic Organ Prolapse (POP), Postoperative Pain
Suzetrigine Following Urogynecologic Surgery: Investigation of Postoperative Pain Management
The goal of this clinical trial is to determine whether suzetrigine, when added to standardized multimodal postoperative analgesia improves pain control and reduces opioid consumption after apical suspension surgery for pelvic…
- Conditions
- Pelvic Organ Prolapse (POP), Postoperative Pain, Urogynecology
- Trial name
- SUSI (NCT07856654)
- Testing
- Suzetrigine
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Aditi Talkad
Pelvic Organ Prolapse
Calistar A vs. Calistar S - Comparative Cohort Retrospective Analysis of Single Incision POP Systems
The main objective of this study is to compare the initial outcomes and complication of two meshes implanted through a single incision to treat anterior and apical prolapses, Calistar A and a second-generation low weight mesh…
- Trial name
- NCT03715803
- Testing
- Calistar A mesh to treat anterior and apical POP, Calistar S mesh to treat anterior and apical POP
- Where
- Argentina
- Volunteers
- 217 people
- Sponsor
- Agustin Sampietro
Hernia, Cystocele
Surgical Treatment To Greater Anterior Vaginal Prolapse
A RCT study to compare traditional colporrhaphy versus polypropylene mesh in treatment of the anterior vaginal wall prolapse.
- Trial name
- Nazcatc™ (NCT00676325)
- Testing
- Surgical treatment of Anterior Vaginal Prolapse, NAZCA TC™ POP REPAIR SYSTEM ,promedon® , argentina., surgical treatment for anterior vaginal wall prolapse
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Pelvic Organ Prolapse, Catheter Infection
Foley Catheterization Following Sacrocolpopexy
The objective of this study is to prospectively evaluate the effects of early versus delayed removal of transuretheral catheters following sacrocolpopexy.
- Conditions
- Pelvic Organ Prolapse, Catheter Infection, Urinary Retention
- Trial name
- NCT01525498
- Where
- United States
- Sponsor
- University of Oklahoma
Vaginal Prolapse
Sacrocolpopexy With Posterior Repair Obstructed Defecation Symptoms
Participants who undergo laparoscopic sacrocolpopexy (LSCP) plus posterior repair (PR) will demonstrate greater improvement bowel symptom scores compared to participants who undergo LSCP alone at 3 months postoperatively.
- Trial name
- NCT03658395
- Testing
- Laparoscopic Sacrocolopopexy, Posterior repair
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Oklahoma
Pelvic Organ Prolapse, Prolapse
PDS Versus Prolene as Suture Material for Vaginal Sacrospinous Hysteropexy
Introduction: Pelvic organ prolapse is a common gynecological disease, which about 50% of women develop in the course of their lives. There are many different options for surgical care, e.g.
- Trial name
- NCT05964881
- Testing
- sacrospinous hysteropexy
- Where
- Austria
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Pelvic Organ Prolapse
Laparoscopic Sacrocolpopexy Versus POPS in the Management of Pelvic Prolapse
This is the first study comparing the laparoscopic sacropexy with Pelvic Organs Prolapse Suspension (POPS) to treat pelvic organ prolapse.
- Trial name
- NCT02911584
- Testing
- Laparoscopic procedure
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Stress Urinary Incontinence, Pelvic Organ Prolapse
Return to Physical Activity After Retropublic Transvaginal Sling and Laparoscopic Sacrocolpopexy
Advice on how long to limit physical activity after pelvic floor surgery ranges from 2 to 12 weeks and rests mainly on local tradition rather than data.
- Trial name
- RETURN (NCT07913815)
- Testing
- Questionnaire and Physical Exam
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Public Healthcare Centre of the Ministry of Interior and Administration