Clinical trials: Pelvic Prolapse
Pelvic Organ Prolapse, Quality of Life
Conservative Management of Symptomatic Pelvic Organ Prolapse Using Vaginal Pessaries: Generation of a Standardized Management Protocol
Genital prolapse is a common condition (up 20%), affecting the quality of life. Treatment can be surgical or conservative using vaginal pessaries. These devices are introduced into the vagina aiming to reduces the prolapse.
- Trial name
- NCT02113969
- Testing
- Vaginal Pessary
- Where
- Chile
- Volunteers
- 294 people
- Sponsor
- Servicio de Salud Metropolitano Sur Oriente
Pelvic Organ Prolapse
Anchor for Robotic Sacrocolpopexy
1. PRIMARY OBJECTIVE: To assess the effect of absorbable anchor compared to suturing for mesh attachment to vagina in robotic assisted sacrocolpopexy on the length of surgery for this portion of the procedure. 2.
- Trial name
- ARiSe (NCT03378622)
- Testing
- Anchor, Suture
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Pelvic Organ Prolapse
Measuring Abdominal Wall Compliance During Gynecologic Laparoscopic Surgery
To measure abdominal wall compliance (AWC) during gynaecologic laparoscopy and assess its relation to the pelvic organ prolapse quantification (POP-Q) score of the same individual, and determine a relationship if present.
- Trial name
- AbComp (NCT05012956)
- Testing
- Laparoscopic sacrocolpopexy, gynecologic laparoscopic surgery
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Incontinence, Prostate Cancer
Urology Database to Evaluate Clinical Information and Improve Patient Care.
The purpose of initiating the Urology Database is to evaluate the outcomes of urology procedures and medical management to enhance the care and treatment of urology patients.
- Conditions
- Incontinence, Prostate Cancer, Interstitial Cystitis, Urinary Retention
- Trial name
- NCT00376298
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- Kenneth Peters, MD
Stress Urinary Incontinence, Pelvic Organ Prolapse
Identifying Stress Urinary Incontinence in Women With Pelvic Organ Prolapse
What test is most sensitive in identifying stress urinary incontinence in women with pelvic organ prolapse; urodynamics, cough stress test, or pyridium pad test? The hypothesis states that there is a difference between the…
- Trial name
- NCT03005977
- Testing
- Urodynamics
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Cleveland Clinic
Urinary Incontinence, Anal Incontinence
Pelvic Floor Muscle Training During Pregnancy
The project seeks to investigate effectiveness of PFMT during pregnancy.
- Conditions
- Urinary Incontinence, Anal Incontinence, Pelvic Organ Prolapse, Sexual Dysfunction
- Trial name
- NCT07104292
- Testing
- PFMT, Standard care
- Where
- Denmark
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Cystocele, Uterine Prolapse
Outcomes of Anterior Colporrhaphy Versus Graft Reinforced Anterior Prolapse Repair
The purpose of this study is determine whether grafted anterior vaginal prolapse repair is more effective and associated with less complications than prolapse repair with suture.
- Conditions
- Cystocele, Uterine Prolapse, Urinary Incontinence
- Trial name
- NCT00535301
- Testing
- grafted anterior prolapse repair, sutured anterior vaginal prolapse repair
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Pelvic Organ Prolapse
Nitrofurantoin Prophylaxis During Catheter-managed Acute Urinary Retention After Pelvic Reconstructive Surgery
The specific aim of this randomized double-blind placebo-controlled trial is to determine if extended release nitrofurantoin antibiotic prophylaxis decreases the incidence of symptomatic urinary tract infection (UTI) compared…
- Trial name
- NCT02727322
- Testing
- Nitrofurantoin
- Where
- 2 sites in United States
- Volunteers
- 154 people
- Sponsor
- Halina M Zyczynski, MD
Pelvic Organ Prolapse, Cystocele
SCP vs HUSLS for Pelvic Organ Prolapse Repair
The purpose of this study is to compare the effectiveness of R-SCP versus HUSLS for treatment of pelvic organ prolapse.
- Conditions
- Pelvic Organ Prolapse, Cystocele, Rectocele, Enterocele
- Trial name
- NCT02800512
- Testing
- Robotic sacrocolpopexy, high uterosacral ligament suspension
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Loma Linda University
Vault Prolapse, Vaginal
Comparison of PHVP of Different VTH Methods
To evaluate the post-hysterectomy vault prolapse (PHVP) rates performed using different methods of vaginal total hysterectomy (VTH).
- Trial name
- NCT03858673
- Testing
- VTH via the Tsuzi method with residual uterine ligament ligation
- Volunteers
- 213 people
- Sponsor
- National Taiwan University Hospital
Pelvic Floor Prolapse, Functional Constipation
Efficacy of Conservative Treatment of Functional Defecatory Disorders in Females With Pelvic Organ Prolapse
This study is planned to evaluate the efficacy of complex conservative treatment (including tibial neuromodulation, biofeedback therapy, special pelvic floor training and diet modification) in women with pelvic organ prolapse
- Conditions
- Pelvic Floor Prolapse, Functional Constipation, Rectocele
- Trial name
- NCT04547816
- Testing
- Biofeedback therapy, Tibial neuromodulation, Pelvic floor muscles training
- Where
- 2 sites in Russia
- Volunteers
- 100 people
- Sponsor
- Federal State Budgetary Scientific Institution
Stress Urinary Incontinence
Effect of Cystocele Repair With Trans Obturator Tape VS. Trans Obturator Tape Alone on Stress Urinary Incontinence.
The goal of this interventional study is to compare the effect of Concurrent cystocele repair and trans obturator tape (TOT) and TOT alone in a sample of Iraqi Female participants with diagnosed stress urinary incontinence and…
- Trial name
- NCT06044987
- Testing
- Trans Obturator Tape Procedure (TOT), Cystocele Repair
- Where
- Iraq
- Volunteers
- 98 people
- Sponsor
- Al-Mustafa University College
Pelvic Organ Prolapse
Study of the Elevate Apical and Posterior Prolapse Repair System Compared to Native Tissue Repair for Pelvic Organ Prolapse
The aim of this study is to further evaluate the safety and efficacy of the Elevate® Apical and Posterior Prolapse Repair System for repair of apical/posterior pelvic organ prolapse in a controlled, post-market cohort study.
- Trial name
- Harmony 522 (NCT02123992)
- Testing
- Elevate Apical and Posterior, Native Tissue Repair for pelvic organ prolapse
- Where
- 23 sites in United States
- Volunteers
- 99 people
- Sponsor
- ASTORA Women's Health
Rectal Prolapse
TEM Assisted Perineal Rectopexy in Treatment of Rectal Prolapse
Curvilinear incision in the postanal space, through the intersphincteric plane, insertion of Proctoscope of TEM technique and dissection till sacral promontory, insertion of mesh between the rectum and sacrum, post anal repair…
- Trial name
- NCT02609555
- Testing
- TEM perineal rectopexy
- Where
- Egypt
- Volunteers
- 7 people
- Sponsor
- Mansoura University
Pelvic Floor Disorders, Pelvic Organ Prolapse
The Intermediate and Long-term Follow up of Home Based Pelvic Muscle Training
When participants present with symptoms of pelvic organ prolapse (POP) and stress urinary incontinence (SUI), the investigators will perform a comprehensive evaluation and initially provide conservative treatment.
- Conditions
- Pelvic Floor Disorders, Pelvic Organ Prolapse, Stress Urinary Incontinence
- Trial name
- NCT05778552
- Testing
- Home-based pelvic muscle training devices or traditional PFMT at hospital
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Patients With Pelvic Organs Prolapse
Rating Pelvic Organs Prolapse in Women According to the POPQ Method Before and After Emptying the Urinary Bladder
Pelvic organ prolapse is a common disorder that affects 3-9% of adult women. Treatment of this disorder varies and includes conservative and interventional treatment.
- Trial name
- NCT01518296
- Testing
- Medtronic-Dantec Urodynamic System
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Carmel Medical Center
Pelvic Organ Prolapse
Pectopexy for Apical Prolapse Management
This study was designed to evaluate the efficacy of pectopexy for treatment of apical pelvic organ prolapse at follow up at 12 months.
- Trial name
- NCT06369857
- Testing
- Pectopexy
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Assiut University
Pelvic Organ Prolapse
Trial Comparing Laparoscopic Vs Robotic-assisted Colposacropexy for Pelvic Organ Prolapse Repair
The aim of the study is to perspectively compare the anatomical and functional outcomes of Pelvic Organ Prolapse (POP) repair after Laparoscopic or Robotic-assisted Colposacropexy.
- Trial name
- NCT02852512
- Testing
- sacrocolpopexy
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- University Of Perugia
Vaginal Vault Prolapse
Laparoscopic Sacropexy With Robot-Assisted Surgical System
The aim of the study is to evaluate safety and outcome of robot-assisted laparoscopic sacropexy regarding perioperative data, objective anatomical results and postoperative quality of life.
- Trial name
- RobPex (NCT00886223)
- Testing
- laparoscopic robot-assisted sacropexy
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kantonsspital Aarau
Urinary Incontinence, Anal Incontinence
Prenatal Pelvic Floor Prevention (3PN)
Objective: Compare pelvic floor disorders (urinary incontinence, anal incontinence, genital prolapse, perineal pain, sexual troubles) 12 month after a first delivery between a group of women with prenatal pelvic floor exercises…
- Conditions
- Urinary Incontinence, Anal Incontinence, Genital Prolapse
- Trial name
- NCT00551551
- Testing
- Pelvic floor muscle training with physiotherapist, Written information about kegel exercises
- Where
- 5 sites in France
- Volunteers
- 280 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion