Clinical trials: Penetrating Injury
Diabetes, Wound Infection
Tebipenem (SPR994) Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis
This study will determine the tissue penetration of a broad-spectrum orally bioavailable carbapenem, tebipenem pivoxil hydrobromide (SPR994) (Spero Therapeutics, Inc.), into the extracellular, interstitial fluid of soft tissue in…
- Conditions
- Diabetes, Wound Infection, ABSSSI, Healthy Volunteers
- Trial name
- NCT04919954
- Testing
- Tebipenem Pivoxil Hydrobromide
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Laparoscopic Surgery
Laparoscopic Splenectomy in Isolated High Grades Splenic Injuries
Background: Trauma laparoscopic splenectomy has no defined reasons. Compared trauma patient characteristics and results with laparoscopic and open splenectomies.
- Trial name
- NCT04329845
- Testing
- open splenectomy, laparoscopic splenectomy for splenic injury in trauma
- Volunteers
- 2 people
- Sponsor
- Zagazig University
Diet, Healthy, Food
The PASTDUe Nutrition Ecosystem Project (PASTDUe)
This is a research study to determine if a particular method of providing nutrition improves the clinical outcomes of patients in the intensive care unit (ICU) who have undergone abdominal surgery and would require nutrition…
- Conditions
- Diet, Healthy, Food, Nutrition, Intensive Care
- Trial name
- PASTDUe (NCT05127109)
- Testing
- Nutrition Ecosystem pathway, Comparator
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Duke University
Wounds, Gunshot
Helping Individuals With Firearm Injuries
The investigators will conduct a cluster randomized trial of an intervention program that combines a hospital-based intervention, structured outreach program, and multi-agency attention.
- Trial name
- HIFI (NCT02630225)
- Testing
- Critical Time Intervention, Treatment as Usual, Motivational Interviewing
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- University of Washington
Abdominal Injuries, Wounds and Injuries
Predictors of In-Hospital Mortality in Severe Abdominal Trauma
Severe abdominal trauma is a leading cause of early death from bleeding and of later death from sepsis and organ failure. Clinicians use scoring systems to estimate the risk of dying, but most of these scores were developed and…
- Conditions
- Abdominal Injuries, Wounds and Injuries, Wounds, Nonpenetrating, Wounds, Penetrating
- Trial name
- NCT07843628
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Minia University
TMJ Disorder
Pulsed Electromagnetic Field Therapy for TMJ Dysfunction After Facial Penetrating Injury
This study is aiming to investigate the effect of magnetic therapy in combination with traditional physical therapy on the pain and mouth opening, after facial penetrating wound injury with no facial fractures, that treated…
- Trial name
- NCT04561037
- Testing
- Pulsed Electromagnetic Field therapy (PEMFT), TMJ physical therapy program
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Kafrelsheikh University
Needle Stick
Simulated Clinical Use Testing On Safety Lancets (Test B)
A simulated clinical use testing on the HTL-Strefa's safety lancets
- Trial name
- NCT03811444
- Testing
- Haemolance Plus safety lancet, Prolance safety lancet, MediSafe Solo safety lancet
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- HTL-Strefa S.A.
Abdominal Injuries, Alcohol Intoxication
Alcohol, Psychoactive Drugs, Analgesics and Evaluation in Penetrating Abdominal Trauma
This prospective observational study aims to evaluate whether alcohol consumption, psychoactive drug use, or prior administration of analgesics affects the clinical evaluation and surgical decision-making process in patients with…
- Conditions
- Abdominal Injuries, Alcohol Intoxication, Substance-related Disorders, Penetrating Abdominal Trauma
- Trial name
- DIRECT (NCT07330349)
- Testing
- Alcohol consumption, Psychoactive substance use, Analgesic administration
- Where
- 2 sites in Colombia
- Volunteers
- 363 people
- Sponsor
- Fundacion Clinica Valle del Lili
Needle Stick
Simulated Clinical Use Testing on Safety Lancets (Test A)
A simulated clinical use testing on the HTL-Strefa's safety lancets
- Trial name
- NCT03807635
- Testing
- ergoLance safety lancet, Acti-Lance safety lancet
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- HTL-Strefa S.A.
Sharps Injuries, Needlestick Injuries
AI-Supported Gamified Training for Sharps Injury Prevention in Nurses
This study aims to evaluate the effect of a Health Belief Model (HBM)-based, artificial intelligence (AI)-supported gamified training program on nurses' knowledge and attitudes toward the prevention of sharps injuries.
- Conditions
- Sharps Injuries, Needlestick Injuries, Occupational Exposure
- Trial name
- NCT07562867
- Testing
- Experimental: Intervention Group, control group
- Volunteers
- 36 people
- Sponsor
- Baskent University
Education Training, Nursing Skills
"Effectiveness of Basic Nursing Educational Interventions on Primary Healthcare Paramedics: A Quasi-Experimental Approach"
Expected Significance of the Study: Improved Patient Outcomes: Paramedics often serve as the first point of contact for patients in primary healthcare settings.
- Conditions
- Education Training, Nursing Skills, Primary Healthcare, Education, Nursing
- Trial name
- NCT06523907
- Testing
- Intervention Basic Nursing skills, Control Present Knowledge about basic nursing skill
- Where
- Pakistan
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- SINA Health Education and Welfare Trust
Fracture at Wrist and/or Hand Level, Rupture of Tendon of Wrist and Hand
USG Brachial Plexus Block for Upper Extremity Surgery
Ultrasound-guided (USG) brachial plexus (BP) block efficacy at the Supraclavicular (SCL), Lateral- Infraclavicular (LIC) and Axillary (AX) level: Randomized, observer-blinded study of the single-penetration…
- Conditions
- Fracture at Wrist and/or Hand Level, Rupture of Tendon of Wrist and Hand, Injuries to the Wrist, Hand and Fingers (S60-S69), Ganglion Cysts
- Trial name
- NCT01993290
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Jens Borglum Neimann
Diabetes, Wound Infection
Omadacycline Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis
This study will determine the tissue penetration of the novel tetracycline antibiotic, omadacycline (Nuzyra, Paratek Pharmaceuticals, Inc.), into the extracellular, interstitial fluid of soft tissue in diabetic patients with…
- Conditions
- Diabetes, Wound Infection, Healthy Volunteers
- Trial name
- NCT04144374
- Testing
- Omadacycline, Microdialysis Catheter Insertion
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Head Injuries With Non Missile Penetrating Objjects
Non-missile Penetrating Head Trauma,Cases Registry in Sohag University Hospital
A retrospective study was done in Neurosurgery trauma unit, Sohag University. Eighteen patients reported with different mechanisms of trauma. All patients clinically tested involving neurological evaluation.
- Trial name
- trauma (NCT03768778)
- Testing
- Debridement and dural repair
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sohag University
Mass Casualty Incidents
Impact of Ten Second Triage vs. Sieve on Triage Performance in Simulated Mass-Casualty Incidents
This study will compare two emergency triage algorithm - Ten Second Triage (TST) versus Sieve - to see which one works better during simulated mass-casualty incidents.
- Trial name
- NCT07436052
- Testing
- Ten Second Triage algorithm, Sieve triage algorithm
- Where
- Switzerland
- Volunteers
- 201 people
- Sponsor
- Stuby Loric
Marginal Ulcer, Chronic Ulcer Disease
Chronic Marginal Ulcers After Gastric Bypass
The purpose of this study is to determine the feasibility, safety, and efficacy of revision gastroplasty along with other adjunct procedures in the treatment of intractable / chronic marginal ulcers after Roux-en-Y gastric…
- Conditions
- Marginal Ulcer, Chronic Ulcer Disease, Persistent Ulcer Disease, Recurrent Ulcer Disease
- Trial name
- ChronicMU (NCT01041079)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
Hepatitis C
HCV Post-Exposure Prophylaxis for Health Care Workers
This is an unblinded, observational trial of sofosbuvir-velpatasvir in adult health care workers who are exposed to hepatitis C virus from needlestick injury with hollow-bore needles.
- Trial name
- NCT03313414
- Testing
- Sofosbuvir/Velpatasvir Treatment for 14 days
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Needlestick Injuries
The Influence of Lidocaine Temperature on Pain During Subcutaneous Administration
This study will investigate the influence of lidocaine temperature on pain during injection of lidocaine. Each participant will receive three injections subcutaneously on the abdomen with different temperatures.
- Trial name
- NCT02107690
- Testing
- Low temperature lidocaine injection, Room temperature lidocaine injection, Body temperature lidocaine injection
- Where
- Norway
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Newborn, Pain Management
Effects of Three Different Methods in Reducing Pain During Heel Blood Collection
This prospective study is planned as a randomized controlled study with the purpose of determining the effect of Breastfeeding, Vibration, and Breastfeeding+Vibration on pain levels during heel blood collection on healthy term…
- Conditions
- Newborn, Pain Management, Breastfeeding, Vibration
- Trial name
- NCT06741670
- Testing
- Breastfeeding, Vibration, Breastfeeding+Vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Burdur Mehmet Akif Ersoy University
Neonatal Pain
ShotBlocker During Intramuscular Injection Randomized Control Trial
The objective of this trial is to evaluate the effect of Bionix ShotBlocker on pain of injection of the first Hepatitis B vaccine in healthy newborns.
- Trial name
- NCT06624176
- Testing
- Bionix ShotBlocker, Swaddling, Sucrose administration
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Lauren Fortier