Clinical trials: Penile Diseases
Hypospadias
The Effect of Caudal Block on the Postoperative Complications in Pediatric Patients After Hypospadias Repair
Hypospadias refers to a disease represented by a congenital defect in the urethra meatus (urinary opening) in male children. Due to the postoperative pain, symptoms such as discomfort, agitation, and restlessness are generally…
- Trial name
- NCT02164682
- Testing
- IV PCA group, IV PCA+ caudal block group
- Where
- South Korea
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Hypospadias
Analgesia in Pediatric Hypospadias Surgeries
The primary aim of the current study will be to use the duration until the first postoperative analgesic requirement after two different block techniques to compare the analgesic effect.
- Trial name
- NCT06410482
- Testing
- US guided caudal block, Dorsal penile nerve block
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Assiut University
Disorder of Sex Development, Intersex Conditions
Decision Support for Parents Receiving Information About Child's Rare Disease
The birth of a child with a disorder of sex development (DSD) is stressful for parents and members of the healthcare team. The "right" decisions about gender assignment (is it a boy? a girl?) and the best course of action (e.g.…
- Conditions
- Disorder of Sex Development, Intersex Conditions, Congenital Adrenal Hyperplasia, Hypospadias
- Trial name
- DSD DST (NCT01875640)
- Where
- 4 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Peyronie Disease
Extracorporeal Shockwave Therapy in the Treatment of Peyronie's Disease
Investigation of the effectiveness of extracorporeal shock wave therapy in the treatment of Peyronie's disease.
- Trial name
- NCT07317297
- Testing
- Extracorporeal Shockwave Therapy, control
- Where
- Azerbaijan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Stress, Job, PTSD
The Sequestration of Holistic Stress Management Techniques for Adults
This remote study is intended to assist the population with access to cost-effective pastoral counseling for stress management in the workplace and every day life.
- Conditions
- Stress, Job, PTSD, Hypervigilance, Hyperthyroidism
- Trial name
- NCT06098755
- Testing
- Holistic Medicine (HM)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Goddess Zena I. Jones
Pain, Postoperative, Phimosis
Evaluating Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision
Circumcision is the most common surgical procedure performed by Pediatric Urologists. Ketorolac has been shown to have an efficacy similar to morphine in multi-modal analgesic regimens without the commonly associated adverse…
- Conditions
- Pain, Postoperative, Phimosis, Paraphimosis, Balanitis
- Trial name
- NCT02973958
- Testing
- Bupivacaine, Sevoflurane, Acetaminophen
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Hypospadias
The Change of the Detrusor Thickness After Hypospadias Repair - Comparison With the Normal Control Group
Even successfully managed hypospadias without any complication, voiding problem could be developed due to the increased urethral resistance.
- Trial name
- NCT01762007
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yonsei University
Penile Infection, Penile Haematoma
Evaluation of the Acceptability and Safety of the ShangRing Device for Male Circumcision in Shinyanga, Tanzania
The goal of this observational study was to evaluate the safety and acceptability of the ShangRing device for male circumcision among men in Shinyanga, Tanzania.
- Conditions
- Penile Infection, Penile Haematoma, Penile Bleeding, Deformity
- Trial name
- NCT06273696
- Testing
- ShangRing
- Where
- 2 sites in Tanzania
- Volunteers
- 575 people, healthy volunteers welcome
- Sponsor
- IntraHealth International
Analgesia
Combination Analgesia for Neonatal Circumcision
Circumcision is a commonly performed procedure on newborn males. Clear recommendations and/or guidelines for pain control during the procedure do not exist.
- Trial name
- NCT02990364
- Testing
- Sucrose, Lidocaine, EMLA Topical Product
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Genital Wart, Penile Cancer
A Phase III Study to Evaluate the Efficacy, Immunogenicity and Safety of the 9-valent HPV Vaccine in Chinese Males
This study is designed to evaluate the vaccine efficacy, immunogenicity and safety of the 9-valent (Types 6, 11, 16, 18, 31, 33, 45, 52 and 58) Human Papillomavirus (HPV) Recombinant Vaccine (Hansenula Polymorpha) in Chinese male…
- Conditions
- Genital Wart, Penile Cancer, Anal Cancer, PIN-1
- Trial name
- NCT06465914
- Testing
- 9-valent Human Papillomavirus (Types 6, 11, 16, 18, 31, 33, 45, 52 and 58) Recombinant Vaccine (Hansenula Polymorpha)
- Where
- 5 sites in China
- Volunteers
- 9,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Bovax Biotechnology Co., Ltd.
Hypospadias
Reconstructing Forked Corpus Spongiosum in Hypospadias Repair
Hypospadias is one of the most common genital malformations in children. The high incidence of hypospadias, which occurs in 1 in 200 to 300 live births, means that it affects a large number of patients.
- Trial name
- NCT04533477
- Testing
- Reconstructing forked corpus spongiosum (FCS), Routine standardized surgery
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Bacterial Vaginosis, Microbial Colonization
The Genital Microbiome of Male Partners of Women With Recurrent BV Undergoing Vaginal Microbiome Transplantation
There is strong observational evidence that sexual activity plays a key role in Bacterial Vaginosis (BV) acquisition and recurrence.
- Trial name
- NCT05963711
- Testing
- chlorhexidine gluconate 4%
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Human Papilloma Virus, Cervical Cancer
Integrating a Health Information Technology System for Primary and Secondary Cervical Cancer Prevention
The project aims to increase HPV vaccination and cervical cancer screening through a web-based mobile health education program called, Wheel of Wellness (WoW) and a brief negotiated interview (BNI).
- Conditions
- Human Papilloma Virus, Cervical Cancer, Human Papillomavirus Infection, Oropharyngeal Cancer
- Trial name
- NCT03346915
- Testing
- WoW and BNI
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Pain, Postoperative, Phimosis
An Evaluation of Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision
Circumcision is the most common surgical procedure performed by Pediatric Urologists. Ketorolac has been shown to have an efficacy similar to morphine in multi-modal analgesic regimens without the commonly associated adverse…
- Conditions
- Pain, Postoperative, Phimosis, Paraphimosis, Balanitis
- Trial name
- NCT04646967
- Testing
- Bupivacain, Sevoflurane, Acetaminophen
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Caudal Block, Pediatric Urologic Surgeries
Comparison of Caudal Block Combined With General Anesthesia and Penile Block and Intravenous Fentanyl in Pediatric Surgeries
Urogenital surgery is one of the most frequently performed surgical procedures in the pediatric patient population. There is no consensus on which analgesic method is most effective for pain control in these patients.
- Conditions
- Caudal Block, Pediatric Urologic Surgeries, Fentanyl, Pediatric Delirium
- Trial name
- NCT06862271
- Testing
- Group 1 ( Caudal block group ), Group 2 (Penile block and IV Fentanyl group)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Miray Gözde Özdemir
Arterial Hypertension, Erectile Dysfunction
Effects of Sildenafil on Penile Vascular Function in Hypertensive Men With Erectile Dysfunction
The study will evaluate the effects of a chronic 30-day treatment with sildenafil citrate on penile and systemic microvascular function as well as in blood pressure.
- Trial name
- NCT02620995
- Testing
- sildenafil citrate, comparator group
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Hypospadias
Liposomal Bupivacaine vs Standard Penile Block for Hypospadias Repair
The investigator proposes a prospective randomized study of males with hypospadias to either bupivacaine penile block or liposomal bupivacaine block for hypospadias repair, Figure 3.
- Trial name
- NCT04479371
- Testing
- Liposomal bupivacaine, Bupivacaine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Erectile Dysfunction
Randomized Trial of Ropivacaine & Bupivacaine for Inflatable Penile Prosthesis
The purpose of this research is to determine the effects of penile ring block for local anesthesia with liposomal bupivacaine vs ropivacaine mixture in subjects undergoing surgery for Penile Prosthesis Placement.
- Trial name
- ROVEX-IPP (NCT04801368)
- Testing
- Randomization of two local anesthetics.
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Priapism, Reperfusion Injury
Investigation of the Protective Effect of Alpha Lipoic Acid on Ischemic Reperfusion Damage in Ischemic Priapism in Rats
The condition known in medical terminology as 'Priapism' refers to the state of erection in the male sexual organ persisting partially or completely for more than 4 hours without sexual stimulation or orgasm.
- Trial name
- NCT07391709
- Testing
- Ischemic priapism + reperfusion, Ischemic priapism + reperfusion + ALA
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Erectile Dysfunction
Feeling Hot 1: Environmental Influences of Overnight Measurement on Skin Temperature of the Erectile Penis
The Feeling Hot studies focus on the proof-of-principle of using temperature sensing as a tool to detect nocturnal erections. In the Feeling Hot 1 study the influence of environmental factors of overnight measurements are studied…
- Trial name
- NCT05183581
- Testing
- Feeling Hot sensor system
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- St. Antonius Hospital