Clinical trials: Penile Diseases
PRF, Hypospadias
A Multicenter Randomized Controlled Trial Comparing Platelet-Rich Fibrin and Ventral Dartos Flap as Intermediate Layers in Tabularized Incised Plate (TIP) Urethroplasty for Distal Hypospadias With Mild Penile Curvature
Distal hypospadias is the most common form of hypospadias. The Tubularized Incised Plate (TIP) repair is the standard surgical technique for this condition; however, complications such as fistula formation and meatal stenosis…
- Conditions
- PRF, Hypospadias, Distal Hypospadias, Hypospadias Repair
- Trial name
- PRF (NCT07045545)
- Testing
- - Group A: Platelet-rich fibrin membrane prepared intraoperatively and applied over neourethra, Group B: Ventral dartos flap rotated over neourethra
- Where
- Uzbekistan
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- National Children's Medical Center, Uzbekistan
Erectile Dysfunction, Penile Prosthesis; Complications, Infection or Inflammation
Irrisept vs Traditional Antibiotic Irrigation for Virgin Penile Prosthesis Placement
The purpose of this study is to assess whether intraoperative irrigation with Irrisept is not inferior to irrigation with multiple antibiotics during placement of a first time inflatable penile prosthesis device.
- Trial name
- NCT06489431
- Testing
- Chlorhexidine, Gentamicin, Rifampin
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Organic Erectile Dysfunction
Assessment of Penile Vibratory Stimulation Using the Viberect in Men With Mild-Moderate ED
The primary objective of this study is to assess the safety, acceptability, and satisfaction of penile vibratory stimulation in treatment of erectile dysfunction (ED).
- Trial name
- NCT01715571
- Testing
- Viberect
- Where
- 2 sites in United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Pain, Hypospadias
Dexmedetomidine Infusion and Surgical Pleth Index In Pediatrics
This non-invasive dimensionless score index -SPI-reflects the Patients' sympathetic response to surgical stimulation. Its effectiveness in detecting the balance between nociceptor activation and analgesia was not only reported…
- Trial name
- NCT05727969
- Testing
- Dexmedetomidine, Lactated Ringer, Hypospadias
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Phimosis
Does Neurostimulation Improve Efficacy for Ultrasound-Guided Transperineal Pudendal Nerve Block In Children
This study aim to compare efficacy of transperineal pudendal nerve block between 2 techniques, by dual guidance (ultrasound and neurostimulation) vs by ultrasound-guided only, in pediatric patients who undergo circumcision.
- Trial name
- NCT03931850
- Testing
- Pudendal nerve block
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ramathibodi Hospital
Transgenderism, Erectile Dysfunction
Erectile Aid Use in Post-phalloplasty and Post-metoidioplasty Transgender Patients
This study seeks to explore the various methods used by transgender men for sexual intercourse following phalloplasty or metoidioplasty, focusing on their satisfaction with different erectile aids, as well as the satisfaction of…
- Conditions
- Transgenderism, Erectile Dysfunction, Gender Dysphoria, Sexual Dysfunction
- Trial name
- AID (NCT06639763)
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Hypospadias
The Role of "Hypospadias Objective Scoring Evaluation" (HOSE) and Uroflowmetry in Evaluation of Successful Hypospadias Repair
Hypospadias is a common anomaly of the male genitalia affecting 0.4-8.2 of 1000 live male babies and varies considerably in severity.
- Trial name
- NCT05032222
- Testing
- Uroflowmetry
- Where
- Egypt
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Mohammad Alaa Ezzat
Hypospadias
A Multimodal Study of the Relationship Between Exposure to Endocrine Disruptors and Occurrence of Hypospadias - HYPOLLUT
This study aims to demonstrate the impact of Endocrine-Disrupting Chemicals (EDCs) on the risk of hypospadias incidence. It is a multicenter comparative case-control study, involving two groups.
- Trial name
- HYPOLLUT (NCT06628375)
- Testing
- Consultation visit (Visit 1)
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Ultrasound Imaging, Caudal Block
Out Of-plane Technique Against In-plane for Caudal Block
Caudal block is an easy and effective type of central neuraxial block that is widely used in subumbilical surgeries to provide intraoperative and postoperative analgesia in the pediatric population.
- Conditions
- Ultrasound Imaging, Caudal Block, Hypospadias
- Trial name
- NCT04671992
- Testing
- Out of-Plane Technique and In-Plane on
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Erectile Dysfunction
the Diagnostic Value of Rigiscan Test (Nocturnal Penile Tumescence and Rigidity, NPTR) in Chinese Males
The purpose of this study is to evaluate the diagnostic value of Rigiscan (nocturnal penile tumescence and rigidity, NPTR ) test in erectile dysfunction of Chinese males.
- Trial name
- NPTR (NCT02573805)
- Testing
- Rigiscan test
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Hypospadias
Snodgrass Versus Grafted Snodgrass Repair in Narrow Urethral Plate in Distal Penile Hypospadias
We aime to compare between Snodgrass and grafted Snodgrass repair in the outcome in distal penile hypospadias with urethral plate less than 8mm
- Trial name
- NCT06405763
- Testing
- Snodgrass repair, Snodgrass repair with graft
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Erectile Dysfunction
Wound Healing Following Penile Prosthesis Implant
This is a prospective, randomized, clinical study aimed to evaluate the safety and efficacy of the two treatment schedules on men undergoing penile implant surgery for the first time.
- Trial name
- NCT05196191
- Testing
- VIAGENEX Max, Hibiclens wash
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- VIVEX Biologics, Inc.
Anesthesia, Anesthesia, Local
Caudal Block Versus Dorsal Penile Nerve Block Plus Ring Block for Pain Management of Different Surgical Techniques of Circumcision in Infants and Children
Circumcision is one of the most commonly performed operations in the pediatric population and is a painful procedure. Circumcision is performed with two popular techniques, Plastibell and conventional dissection method (CDM).
- Conditions
- Anesthesia, Anesthesia, Local, Analgesia, Pediatric ALL
- Trial name
- NCT05233683
- Testing
- Caudal block, Dorsal penile nerve block plus ring block, Circumcision with Plastibell
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Saud University
Healthy, Cyclists
Effects of Contemporary Cycling Saddle Designs on Penile Transcutaneus Oxygen and Carbon Dioxide Levels in Elite Road Cyclists Riding on a Stationary Trainer
Aim of this research is to compare novel 3D printed cycling saddle with the bestselling saddles from two major cycling manufacturers in terms of effects on penile blood gasses and update these findings on current style of racing…
- Conditions
- Healthy, Cyclists, Blood Gas Monitoring, Transcutaneous, Penile Numbness
- Trial name
- EC-SADDLE (NCT05887193)
- Testing
- Biothesiometry, Transcutaneous blood gas monitoring, Cycling on a home trainer
- Where
- Czechia
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Milan Martínek
Erectile Dysfunction, Prostate Cancer
Erectile Recovery After Robotic-Assisted Laparoscopic Prostatectomy
The study is a prospective, randomized, double-blind, placebo-controlled drug study to evaluate the pattern of erectile function recovery after robotic assisted laparoscopic prostatectomy (RALP).
- Trial name
- NCT03406169
- Testing
- Sildenafil 25 MG Oral Tablet, Pentoxifylline
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Hypospadias
Identification of Hypospadias Parameters Using Digital Photography and Artificial Intelligence
The goal of this observational study is to develop and validate a digital pattern recognition system based on artificial neural network to determine various parameters in hypospadias.
- Trial name
- ASHOKA (NCT05569863)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Human Immunodeficiency Virus (HIV)
SPL7013 Gel - Male Tolerance Study
The purpose of this study is to determine if SPL7013 Gel (VivaGel™) is safe when applied topically once a day for seven consecutive days to the shaft and glans of the penis in healthy male volunteers.
- Trial name
- NCT00370357
- Testing
- 3% w/w SPL7013 Gel (VivaGel™)
- Where
- Australia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Starpharma Pty Ltd
Phimosis, Paraphimosis
Evaluating the Efficacy of 2-Octyl Cyanoacrylate (2-OCA) With Four Interrupted Sutures in Adult Male Circumcision
This study aims to determine whether cyanoacrylate glue is a non-inferior alternative to continuous suturing for wound closure following adult circumcision.
- Trial name
- NCT06487494
- Testing
- Circumcision wound closure using 2-octyl cyanoacrylate glue with four interrupted sutures, Circumcision wound closure using continuous sutuing
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manitoba