Clinical trials: Penile Surgery
Urinary Bladder Neoplasms, Prostatic Neoplasms
Lymphedema After Urologic Surgery
Lymphedema of the extremities is common after lymph node surgery in treating several forms of cancer, e.g., breast cancer. However, very little is known of the occurrence of lymphedema of the lower extremities after urologic…
- Conditions
- Urinary Bladder Neoplasms, Prostatic Neoplasms, Testicular Neoplasms, Penile Cancer
- Trial name
- NCT05264337
- Testing
- Self-reported lymphedema, Dielectric constant ratio, Limb volume
- Where
- 2 sites in Sweden
- Volunteers
- 400 people
- Sponsor
- Vastra Gotaland Region
Transsexualism, Surgery
Use of an External Erectile Device in Transgender Man Following Phalloplasty
The purpose of this study is to test whether an external erectile prosthesis (The Elator™) is a feasible alternative to internal erectile prostheses for transgender men who have undergone a phalloplasty with glansplasty and wish…
- Conditions
- Transsexualism, Surgery, Sex Behavior, Erectile Dysfunction
- Trial name
- ProstHEsis (NCT03823014)
- Testing
- Elator
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Analgesia
Analgesia for Perineal Surgeries in High-risk Pediatric Patients
Perioperative pain management in pediatric patients, especially for anorectal and penile surgeries, presents significant challenges for anesthetists.
- Trial name
- NCT07602894
- Testing
- Systemic analgesia, Sacral multifidus plane block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Hypospadias, Hypospadias, Coronal
Comparison Between Ultrasound Guided Caudal Block and Ultrasound Guided Dorsal Penile Block in Hypospadias Surgery in Children
The study focuses on comparing the caudal block (CB) and the dorsal penile nerve block (DPNB) via ultrasound guidance in regional anesthesia in hypospadias surgery.
- Trial name
- NCT07615335
- Testing
- Caudal Block Anesthesia, Dorsal Penile Block Anesthesia
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Ahmed Aouf
Penile Cancer, Recurrent
Prediction of Local Recurrence and Its Impact on Long-term Outcomes After Low-risk Glans-sparing Surgery for Penile Squamous Cell Carcinoma
The treatment paradigm for primary penile squamous cell carcinoma (PSCC) has increasingly favored maximal organ preservation without compromising oncological outcomes.
- Trial name
- NCT06565585
- Testing
- Glans-sparing surgery
- Where
- Belgium
- Volunteers
- 800 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Penis/Surgery, Fixation
A Novel Suspensory Ligament Penodermal Fixation Technique Versus Dorsal Tunica Albuginea Fixation for Pediatric Buried Penis:
The aim of the work to compare the outcomes of suspensory ligament fixation to the sub-dermis and dorsal tunica albuginea fixation in terms of success rate, need for auxiliary procedures, and complication rates in the buried…
- Conditions
- Penis/Surgery, Fixation, Ligament
- Trial name
- NCT07675915
- Testing
- Group A: Suspensory ligament fixation, Group B: Tunica albuginea fixation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Head and Neck Cancer, Penile Cancer
INtra-operative Evaluation of a Novel FLUorescENt C-mEt Tracer in Penile and Tongue
In this study we evaluate the feasibility of intraoperative visualization of penile and tongue tumours using the fluorescent tracer EMI-137.
- Trial name
- INFLUENCE (NCT04574427)
- Where
- Netherlands
- Volunteers
- 5 people
- Sponsor
- The Netherlands Cancer Institute
Complication of Surgical Procedure
Outcomes of Surgical Correction of Penile Curvature in Adult
Penile curvature in adults is divided into two main categories the first is congenital penile curvature with orthotopic meatus and the other is acquired curvature which its common causes are Peyronie's disease (PD) and previous…
- Trial name
- NCT03313986
- Volunteers
- 50 people
- Sponsor
- Assiut University
Hypospadias
PREDICT-H Study: Prospective Research on Essential Determinants Influencing Complication Trends in Hypospadias - a Landmark Prospective Multicenter Cohort Study Aimed at Improving Outcome Prediction in Hypospadias Surgery
Hypospadias is a common congenital anomaly with complex anatomy that influences surgical outcomes. Despite numerous surgical techniques, a lack of standardized preoperative assessment protocols and consensus on anatomical risk…
- Trial name
- PREDICT-H (NCT07017842)
- Where
- Qatar
- Volunteers
- 1,300 people
- Sponsor
- Sidra Medicine
Amputation, Wounds and Injuries
Human Penile Allotransplantation
Injuries to the genitalia are of concern to the military with emphasis placed on the surgical reconstruction and psychological health of these Wounded Warriors.
- Conditions
- Amputation, Wounds and Injuries, Amputation, Traumatic, Urologic Surgical Procedures, Male
- Trial name
- NCT02395497
- Testing
- Monoclonal Antibody (Humanized Anti-CD52), Tacrolimus, Penile Allotransplantation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
Squamous Cell Carcinoma of the Penis, Usual Type
International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study)
This is an international phase III trial, with a Bayesian design, incorporating two sequential randomisations. It efficiently examines a series of questions that routinely arise in the sequencing of treatment.
- Trial name
- InPACT (NCT02305654)
- Testing
- ILND - Inguinal Lymph Node Dissection, Paclitaxel, Ifosfamide
- Where
- 17 sites in United States, United Kingdom
- Volunteers
- 200 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Hypospadias
The Role of Local Long Acting Corticosteroid Injection in Hypospadias Surgery.
Post-operative tissue oedema is one of the main causes of failure of hypospadias repair. Severe oedema may disrupt the suture line, invite infection and result in repair failure.
- Trial name
- NCT04196400
- Testing
- steroid betamethasone
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Peyronie Disease
Novel Nanofat Regenerative Surgical Technique for Peyronies' Disease Treatment
Peyronies' disease (PD) is an acquired connective tissue disorder characterized with the growth of fibrous and/or calcified plaques in the tunica albuginea of the penis.
- Trial name
- IPPNANOFAT (NCT05316714)
- Testing
- Nanofat grafing
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- University of Roma La Sapienza
Hypospadias
Efficacy of Fibrin Sealant in Hypospadias Surgery
The aim of the study was to evaluate if application of a fibrin sealant over the urethroplasty suture line for waterproofing instead of a dartos vascularized pedicled flap to reduce complications and improve the outcome in…
- Trial name
- NCT05666206
- Testing
- fibrin sealant in hypospadias
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Al-Azhar University
Penile Cancer, Lymph Node Metastasis
Inguinal Lymphadenectomy for Penile Cancer
The aim of the present study is to prospectively compare oncological and functional results of penile radical inguinal lymphadenectomy performed with an open versus videolaparoscopic technique.
- Conditions
- Penile Cancer, Lymph Node Metastasis, Sentinel Lymph Node, Surgical Complication
- Trial name
- NCT05887921
- Testing
- Inguinal Lymphadenectomy
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Ultrasound Imaging, Caudal Block
Out Of-plane Technique Against In-plane for Caudal Block
Caudal block is an easy and effective type of central neuraxial block that is widely used in subumbilical surgeries to provide intraoperative and postoperative analgesia in the pediatric population.
- Conditions
- Ultrasound Imaging, Caudal Block, Hypospadias
- Trial name
- NCT04671992
- Testing
- Out of-Plane Technique and In-Plane on
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Concealed Penis
Surgical Repair of Pediatric Concealed Penis is Generally Safe and Efficacious. Criteria for Pediatric Concealed Penis Surgical Success Are Still Poorly Standardized, so Our Study Presents a Multi-dimensional Framework Consisting of Morphometric Measurements and Subjective Psychometric Parameters.
A concealed penis (CP) refers to a condition in which the normally-sized penis appears smaller or completely hidden in the prepubic area. Surgical repair of pediatric concealed penis is generally safe and efficacious.
- Trial name
- MPPPS SPL BPL (NCT07615439)
- Testing
- penoplasty by complete penile degloving to release all anomalous restrictive attachments, followed by phallopexy via proper fixation of the penile base
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Eslam Saad Hamza
Erection; Incomplete
Effect of Propofol vs. Sevoflurane on Erections During Narcosis In Transurethral Surgery
Penile erection is an unwanted event in transurethral (through the urethra) surgeries, which may be associated with adverse outcomes such as impaired access, prolonged operation time, the need to abort the operation, or the…
- Trial name
- PENIS (NCT06378645)
- Testing
- General Anesthesia: Propofol, General Anesthesia: Sevoflurane
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Etienne Xavier Keller
Postoperative Pain
Ultrasound Guided Penile Block vs Pudendal Block for Hypospadias
Pain after hypospadias surgery is a challenging issue to solve for anesthesists. Many different analgesia techniques were defined in literature for this purpose.
- Trial name
- NCT03496740
- Testing
- Penile Block, Pudendal Block, Bupivacaine (Block Drug)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Kocaeli University
Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction
Platelet-Rich Plasma for Erectile Dysfunction After Radical Prostatectomy: a Randomized Controlled Trial
This study will test whether injections of platelet-rich plasma (PRP) can improve erectile function in men with persistent erectile dysfunction (ED) at least 12 months after nerve-sparing radical prostatectomy for prostate…
- Trial name
- NCT07863388
- Testing
- Autologous Platelet Rich Plasma
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Herlev and Gentofte Hospital