Clinical trials: Percutaneous Coronary Intervention Patients
ST Elevation Myocardial Infarction, Multi-Vessel Coronary Artery Stenosis
Quantitative Fractional Ratio-guided Revascularization in STEMI Patients With Multi-vessel Disease
About half of patients with ST-segment elevation myocardial infarction (STEMI) have multi-vessel lesions (> 50% diameter stenosis). But how to deal with the non-culprit vessels is still controversial.
- Trial name
- NCT04259853
- Testing
- PCI
- Where
- 15 sites in China
- Volunteers
- 1,016 people
- Sponsor
- Fujian Medical University
Congenital Heart Disease
Safety and Effectiveness of the Device "Nit-Occlud® PDA-R"
The purpose of this study is to evaluate the safety and the effectiveness of the device "Nit-Occlud® PDA-R" in the percutaneous closure of patent ductus.
- Trial name
- NCT01063712
- Testing
- Nit-Occlud® PDA-R
- Where
- Bolivia
- Volunteers
- 29 people
- Sponsor
- pfm S.R.L.
Coronary Artery Disease, Percutaneous Coronary Intervention
Potassium-Competitive Acid Blocker Versus pROton-Pump Inhibitor for GastroproTECTion Strategies In Patients at High Gastro-Intestinal Bleeding Risk Receiving Antithrombotic Therapy
The primary aim of this study is to evaluate the efficacy and safety of novel P-CAB (tegoprazan 50 mg once daily) as compared with standard PPI (rabeprazole 20 mg once daily) for protection of GI events in patients with known…
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, Acute Coronary Syndrome, Myocardial Infarction
- Trial name
- PROTECT-HBR (NCT04416581)
- Testing
- PPI, P-CAB 50
- Where
- 45 sites in South Korea
- Volunteers
- 3,320 people
- Sponsor
- Duk-Woo Park, MD
Coronary Artery Disease
The EFFect of hIgh Dose ClopIdogrel treatmENT in Patients With Clopidogrel Resistance
Continuing high dose clopidogrel treatment after elective PCI decreased adverse cardiac events in patients with clopidogrel resistance
- Trial name
- EFFICIENT (NCT01032668)
- Testing
- Clopidogrel
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people
- Sponsor
- Bursa Postgraduate Hospital
Diabetes Mellitus, Coronary Artery Disease
Coronary Physiology and Its Relationship to Anatomy in Patients With Diabetes Mellitus
Comprehensive assessment of coronary physiology (fractional flow reserve (FFR), coronary flow reserve (CFR) and index of microcirculatory resistance (IMR)) in patients with diabetes mellitus and coronary artery disease (CAD).
- Trial name
- NCT02745821
- Testing
- Pressure Wire Certus, St. Jude Medical, USA
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Ottawa Heart Institute Research Corporation
ST Elevation Myocardial Infarction
Outcome of Primary PCI in STEMI Addict Patients
The goal of this study is to Identify the in-hospital outcome of primary PCI in treatment of STEMI in addict patients in comparison to non-addict patients.
- Trial name
- NCT04090216
- Testing
- Primary Percutaneous Coronary Intervention
- Volunteers
- 176 people
- Sponsor
- Assiut University
Coronary Artery Disease
Comparison of 1 Month vs. 12 Months DAPT in Patients Undergoing PCI With Genoss® DES
This study is a prospective, open-label, multicenter, randomized clinical trial to evaluate the efficacy of 1 month dual antiplatelet therapy (DAPT) with aspirin plus clopidogrel followed by clopidogrel monotherapy, compared with…
- Trial name
- GENOSS-DAPT (NCT05770674)
- Testing
- 1 Month vs. 12 Months DAPT
- Where
- South Korea
- Volunteers
- 2,186 people
- Sponsor
- Kiyuk Chang
Primary Percutaneous Coronary Intervention
Short Term Outcomes of Primary Percutaneous Coronary Intervention (PCI) Patients Presented With Acute Heart Failure in Assuit University Heart Hospital
Observational study outcome of PCI in patients presented with acute heart failure
- Trial name
- NCT06825780
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Coronary Heart Disease, Percutaneous Coronary Intervention
The Relationship Between Anxiety, Depression and Stent Restenosis After Percutaneous Coronary Intervention
Percutaneous coronary intervention is currently one of the effective methods for the treatment of ACS. Unfortunately, the incidence of ISR is as high as 10%-20% at 3-6 months after PCI.
- Trial name
- NCT04811976
- Where
- China
- Volunteers
- 400 people
- Sponsor
- The First Hospital of Qinhuangdao
Percutaneous Coronary Intervention, Anxiety
The Effect of Listening to Music and Stress Ball Application on Patients' Anxiety Level and Hemodynamic Parameters During PCI
In this study, it was aimed to determine the effects of listening to music and applying a stress ball on patients' anxiety level and hemodynamic parameters during percutaneous coronary intervention (PCI).
- Conditions
- Percutaneous Coronary Intervention, Anxiety, Hemodynamics
- Trial name
- NCT05514574
- Testing
- Music, Stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 183 people
- Sponsor
- Keriman Yildiz
Acute Myocardial Infarction
Effects on Health Status in Patients Early Discharged After Primary Percutaneous Coronary Intervention (PCI)
In patients with ST elevation myocardial infarction (STEMI)treated with primary percutaneous coronary intervention (PPCI) a subset with low risk for late complications can be identified.
- Trial name
- INUT (NCT01244841)
- Testing
- fast post MI care
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Helse Stavanger HF
Myocardial Infarction, Acute
Korea Acute Myocardial Infarction Registry
This multicentre observational registry study, the Korea Acute Myocardial Infarction Registry (KAMIR-7), aims to improve long-term prognosis in Korean patients with acute myocardial infarction (AMI) by establishing and operating…
- Trial name
- KAMIR-7 (NCT07409441)
- Where
- 2 sites in South Korea
- Volunteers
- 20,000 people
- Sponsor
- Samsung Medical Center
Atrial Fibrillation, Percutaneous Coronary Intervention
Evaluation of Dual Therapy With Dabigatran vs. Triple Therapy With Warfarin in Patients With AF That Undergo a PCI With Stenting (REDUAL-PCI)
The main objective of this study is to compare a Dual Antithrombotic Therapy (DAT) regimen of 110mg dabigatran etexilate b.i.d. plus clopidogrel or ticagrelor (110mg dabigatran etexilate (DE) DAT) and 150mg dabigatran etexilate…
- Trial name
- NCT02164864
- Testing
- Dabigatran Etexilate 110mg, Warfarin 3mg, Aspirin
- Where
- 421 sites in United States, Argentina and 39 more
- Volunteers
- 2,725 people
- Sponsor
- Boehringer Ingelheim
Diabetes Mellitus, Microvascular Coronary Artery Disease
Study in Diabetes Mellitus Patients Without Prior Myocardial Infarction or Stroke Undergoing Elective Percutaneous Coronary Intervention.
This study is designed to test the hypothesis that ticagrelor is superior to clopidogrel, in improving coronary microvascular function, as measured by coronary flow reserve (CFR) in patients with T2DM at high risk of…
- Trial name
- AUGEAS (NCT04069234)
- Testing
- Ticagrelor, Clopidogrel
- Sponsor
- Region Skane
Acute Coronary Syndrome, High Bleeding Risk
LEADERS FREE II: BioFreedom™ Pivotal Study
This study aims to confirm non-inferiority of the BioFreedom™ Drug Coated Stent to the Gazelle™ Bare Metal Stent arm of the Leaders Free study (NCT01623180) in high bleeding risk patients.
- Trial name
- NCT02843633
- Testing
- BioFreedom™ Drug Coated Coronary Stent System, Antiplatelet Drug
- Where
- 66 sites in United States, Canada and 5 more
- Volunteers
- 1,203 people
- Sponsor
- Biosensors Europe SA
Radial Artery Occlusion, Vascular Access
Transulnar Access in Patients With Ipsilateral Radial Artery Occlusion Undergoing Coronary Angiography or Angioplasty
Coronary angiography and angioplasty are commonly performed through the radial artery at the wrist as this approach is associated with fewer bleeding complications and faster recovery.
- Conditions
- Radial Artery Occlusion, Vascular Access, Coronary Artery Disease (CAD)
- Trial name
- ULNART (NCT07380399)
- Where
- 2 sites in Greece
- Volunteers
- 127 people
- Sponsor
- National and Kapodistrian University of Athens
Chronic Kidney Disease, Multivessel Coronary Artery Disease
Randomized Comparison of xiEnce and visioN Coronary Stents in the sAme muLtivessel Patient With Chronic kiDnEy diSease
Percutaneous coronary intervention (PCI) with bare metal stent (BMS) in patients with renal insufficiency has shown unsatisfactory results.
- Trial name
- RENAL-DES (NCT00818792)
- Testing
- Coronary stent
- Where
- 2 sites in Italy
- Volunteers
- 215 people
- Sponsor
- European Hospital
Coronary Artery Disease
Angiography-Derived FFR And IVUS for Clinical Outcomes in Patients With Coronary Artery Disease
Comparison of Angiography-derived Fractional FLow Reserve And IntraVascular Ultrasound-guided Intervention Strategy for Clinical OUtcomes in Patients with CoRonary Artery Disease
- Trial name
- FLAVOUR II (NCT04397211)
- Testing
- Angiography-derived FFR, IVUS
- Where
- 23 sites in China, South Korea
- Volunteers
- 1,872 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Coronary Artery Disease
Effects of Ticagrelor Versus Prasugrel on Coronary Microcirculation in Patients Undergoing Elective Percutaneous Coronary Intervention: Results of the PROtecting MICROcirculation During Coronary Angioplasty (PROMICRO)-3 Randomised Study
Besides being at least as effective as prasugrel in inhibiting platelet aggregation, ticagrelor has been shown to have additional properties potentially affecting coronary microcirculation.
- Trial name
- PROMICRO-3 (NCT05643586)
- Testing
- Ticagrelor, Prasugrel
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Germano Di Sciascio
CA-AKI - Contrast-Associated Acute Kidney Injury, Coronary Artery Disease
Efficacy of Phentolamine in Prevention of Contrast-Associated Acute Kidney Injury After Complex PCI
To evaluate the efficacy and safety of phentolamine in prevention of CA-AKI following complex PCI in patients at high risk of CA-AKI.
- Conditions
- CA-AKI - Contrast-Associated Acute Kidney Injury, Coronary Artery Disease, Acute Coronary Syndrome, Adrenergic Receptor Antagonist Adverse Reaction
- Trial name
- NCT06286059
- Testing
- Phentolamine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Helwan University