Clinical trials: Percutaneous Coronary Intervention Patients
MACE, In STEMI
"Short-term Outcome in STEMI Patients Undergoing Primary PCI: A Comparative Study Between Rural and Urban Communities at Assiut University."
this study aims to assess the short-term (3-month) clinical and echocardiographic outcomes of primary PCI among STEMI patients from rural versus urban areas in Upper Egypt.
- Trial name
- NCT07136831
- Testing
- Primary Percutaneous Coronary Intervention (PPCI)
- Volunteers
- 162 people
- Sponsor
- Assiut University
ST-elevation Myocardial Infarction
Early Treatment With Evolocumab in Patients With ST-elevation Myocardial Infarction
This is a prospective, multi-centre, open label, randomised study of Phase II that enrolls patients hospitalized with a diagnosis of ST-elevation myocardial infarction (STEMI), comparing Evolocumab versus Standard of Care.
- Trial name
- ExOTIC (NCT04303377)
- Testing
- Evolocumab
- Where
- Italy
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Obstructive Sleep Apnea, ST Elevation Myocardial Infarction
CPAP for OSA on Myocardial Salvage After pPCI for STEMI Patients
The aim of this randomized controlled trial to investigate the effects of CPAP treatment on myocardial salvage index and clinical outcomes at 3 months in patients with OSA and ST-Segment Elevation Myocardial Infarction (STEMI)…
- Trial name
- NCT03444857
- Testing
- Continuous positive airway pressure
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease
A Registry Trial of The Bioheart Rapamycin Drug-Eluting Bioresorbable Coronary Stent System
This study is a prospective, multi-center single arm registry trial, planning to enroll 785 subjects. All subjects will receive clinical follow-up at 1 month, 6 month, 9 month and 1, 2, 3, 4, 5 year after index procedure.
- Trial name
- NCT04179045
- Testing
- The Bioheart Rapamycin Drug-Eluting Bioresorbable Coronary Stent System
- Where
- 5 sites in China
- Volunteers
- 785 people
- Sponsor
- Shanghai Bio-heart Biological Technology Co., Ltd.
Anterior Myocardial Infarction
A Research Study to Evaluate the Safety and Preliminary Efficacy of SGC001 in Patients With Myocardial Infarction
The research study is being done to see if SGC001 can be used to treat people scheduled to undergo percutaneous coronary intervention for Anterior ST-segment Elevation Myocardial Infarction.
- Trial name
- NCT07091929
- Testing
- SGC001
- Where
- 4 sites in China
- Volunteers
- 38 people
- Sponsor
- Beijing Sungen Biomedical Technology Co., Ltd
Depressive Disorder (Per DSM-V Criteria, Mild-to-moderate), Acute Coronary Syndrome (ACS)
Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation on Alleviating Major Depressive Disorder in Patients With Acute Coronary Syndrome After Percutaneous Coronary Intervention:A Prospective, Double-Blind,Randomized Controlled Study
This is a randomized, controlled study. ACS follow- up patients aged 18 to 80 years old with hemodynamic stability, who are 14 days to 1 year after PCI, are screened through the HAMD score and the HAMA score.
- Conditions
- Depressive Disorder (Per DSM-V Criteria, Mild-to-moderate), Acute Coronary Syndrome (ACS), Percutaneous Coronary Intervention (PCI), Depressive Disorder
- Trial name
- NCT07454070
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) Intervention
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Jing Han
Stable Coronary Artery Disease, Percutaneous Coronary Intervention
Effect of Berberine for Endothelial Function and Intestinal Microflora in Patients With Coronary Artery Disease
The purpose of this study is to conduct a single-center, randomized, open-label, controlled, dose-escalating, parallel-group study, evaluating the effects and change of endothelial function and gut microbiota after berberine…
- Trial name
- NCT04434365
- Testing
- Berberine, Aspirin, Clopidogrel
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Peking Union Medical College Hospital
Diabetes Mellitus, Type 2, Coronary Artery Disease
Low Maintenance Dose Ticagrelor Versus Clopidogrel in Diabetes Patients Undergoing PCI
To date there is very little PD and pharmacokinetic (PK) data on the ticagrelor 60 mg bid dosing regimen. In particular, there is no prospective PK/PD study on this dosing regimen in patients with DM who are known to have…
- Trial name
- OPTIMUS-6 (NCT03437044)
- Testing
- Ticagrelor, Clopidogrel
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Florida
Radial Artery Occlusion, Vascular Access
Transulnar Access in Patients With Ipsilateral Radial Artery Occlusion Undergoing Coronary Angiography or Angioplasty
Coronary angiography and angioplasty are commonly performed through the radial artery at the wrist as this approach is associated with fewer bleeding complications and faster recovery.
- Conditions
- Radial Artery Occlusion, Vascular Access, Coronary Artery Disease (CAD)
- Trial name
- ULNART (NCT07380399)
- Where
- 2 sites in Greece
- Volunteers
- 127 people
- Sponsor
- National and Kapodistrian University of Athens
Acute Coronary Syndrome
Tirofiban and Enoxaparin in High Risk Coronary Intervention
Patients undergoing coronary angioplasty are frequently treated with new drugs that stop blood platelets working and so improve the success of the procedure. Individual patients may vary in the dose of the drug required.
- Trial name
- NCT00790387
- Testing
- Enoxaparin, Tirofiban, unfractionated heparin
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Prince Charles Hospital
Diabetes Mellitus, Coronary Artery Disease
Periprocedural Glycemic Control in Patients Undergoing Coronary Angiography
There are 24 million people with diabetes mellitus (DM) in the United States. Over one-third of patients presenting for coronary angiography have known DM, and an additional 20% of patients without known DM present with…
- Trial name
- NCT01419652
- Testing
- hold hypoglycemic meds
- Where
- United States
- Volunteers
- 351 people
- Sponsor
- NYU Langone Health
Coronary Artery Disease, Platelet Reactivity
Pharmacodynamic Outcomes in CCS Patients Treated With an Individualized Treatment Strategy
Patients with Chronic Coronary Syndrome (CCS) undergoing with elective percutaneous coronary intervention (PCI) are treated with dual antiplatelet therapy (DAPT), consisting of aspirin combined with clopidogrel for 6 months.
- Trial name
- NCT05773989
- Testing
- CYP2C19 genotype guided P2Y12 monotherapy, Clopidogrel
- Where
- Netherlands
- Volunteers
- 88 people
- Sponsor
- St. Antonius Hospital
Ischemic Heart Disease, Stenotic Coronary Lesion
RESOLUTE China Registry:
To document the safety and overall clinical performance of the Resolute Zotarolimus-Eluting Coronary Stent System in a real-world patient population requiring stent implantation.
- Conditions
- Ischemic Heart Disease, Stenotic Coronary Lesion, Cardiovascular Diseases, Arteriosclerosis
- Trial name
- R-C Registry (NCT01243749)
- Where
- 6 sites in China
- Volunteers
- 1,800 people
- Sponsor
- Medtronic Vascular
Obstructive Sleep Apnea
Sleep and Stent Study: a Multicentre, Prospective Study
Elucidating the effects of obstructive sleep apnea (OSA) on cardiovascular outcomes is crucial in risk assessments and therapeutic recommendations for affected individuals.
- Trial name
- NCT02215317
- Where
- Singapore
- Volunteers
- 1,815 people
- Sponsor
- National University of Singapore
ST-Segment Elevated Myocardial Infarction
Early rhBNP on Myocardial Work in Patients With STEMI
The study intends to evaluate the efficacy of early rhBNP on myocardial work in patients with anterior ST-segment elevation myocardial infarction after percutaneous coronary intervention
- Trial name
- NCT04157868
- Testing
- rhBNP, Control
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Coronary Artery Disease, Antineoplastic Agents
Bioheart Rapamycin Drug-Eluting Bioresorbable Coronary Stent System Clinical Study
The Bioheart Randomized Controlled Trial is a prospective multicentred paralleled study, which will enroll 430 patients and randomized 1:1 to study group and control group.
- Trial name
- NCT03284255
- Testing
- study group, control group
- Where
- 25 sites in China
- Volunteers
- 431 people
- Sponsor
- Shanghai Bio-heart Biological Technology Co., Ltd.
Coronary Artery Disease, Atherosclerosis
Coronary Artery Disease Progression in Patients With Prediabetes
Prediabetes is a disorder of glucose metabolism that reflects the natural history of progression from normoglycaemia to type 2 diabetes mellitus.
- Conditions
- Coronary Artery Disease, Atherosclerosis, Prediabetic State
- Trial name
- NCT02744976
- Testing
- Metformin, Lifestyle recommendations
- Where
- Latvia
- Volunteers
- 70 people
- Sponsor
- Pauls Stradins Clinical University Hospital
Acute Myocardial Infarction
Effect of N-acetylcystein in Myocardial Infarction
We designed this study to evaluate the effect of N-acetylcystein on biomarkers of platelet activation , cardiac necrosis and coronary reperfusion in patients undergoing percutaneous coronary intervention.
- Trial name
- NCT01741207
- Testing
- N-acetylcystein
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Tehran University of Medical Sciences
Heart Failure
Study of Percutaneous Renal Artery Intervention for Patient With Heart Failure
This study will address the role of percutaneous renal intervention for a hemodynamically significant renal artery stenosis in patients with heart failure exacerbations.
- Trial name
- STRETCH (NCT01403714)
- Testing
- Renal Artery Stenting
- Where
- United States
- Sponsor
- University of Pennsylvania
Drug-eluting Stents, Percutaneous Coronary Intervention
In-stent Repair and Vessel Reaction of STEMI Patients With OCT
This study is a prospective, multi-center, non-inferior, randomized controlled clinical trial, aims to use optical Coherence tomography to observe the the early- and mid-stage vessel repair and neointimal proliferation.
- Conditions
- Drug-eluting Stents, Percutaneous Coronary Intervention, Optical Coherence Tomography, ST-Elevation Myocardial Infarction
- Trial name
- NCT04150016
- Testing
- percutaneous coronary intervention
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Xijing Hospital