Clinical trials: Percutaneous Coronary Revascularization
Coronary Artery Disease (CAD), ST-elevation Myocardial Infarction (STEMI)
Drug-coatEd Balloon Multicentric Registry in Spain and PORTugal
Drug-eluting stents (DES) have been the main treatment option for coronary angioplasty (PCI) for many years. The antiproliferative drug in DES has the effect of preventing in-stent restenosis, which is typically a consequence of…
- Trial name
- DESPORT (NCT07477405)
- Volunteers
- 1,200 people
- Sponsor
- Portuguese Association of Interventional Cardiology
Coronary Artery Disease
A Single Center Clinical Evaluation of Same Sitting Hybrid Revascularization: Robotic Coronary Artery Bypass Grafting and Percutaneous Coronary Intervention for the Treatment of Coronary Artery Disease
The primary objective of this study is to assess the safety and effectiveness of same sitting, simultaneous hybrid robotic assisted coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) in the…
- Trial name
- NCT00928356
- Testing
- Hybrid CABG/PCI, Off Pump CABG
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Pinnacle Health Cardiovascular Institute
Myocardial Infarction
The Relationship Between Myocardial Blush Grade and T-P-e Interval and QRS Width: Impact on In-Hospital Outcome After Successful Primary Percutaneous Coronary Intervention
Aim of the work: Primary aim; is to assess relation between non invasive ECG findings, Tpe interval and QRS width and MBG in in patients with successful PCI in patients with STEMI.
- Trial name
- NCT05593822
- Testing
- primary percutaneous intervention
- Volunteers
- 80 people
- Sponsor
- Assiut University
ST-segment Elevation Myocardial Infarction
Remote Ischemic Perconditioning in Patients With ST-segment Elevation Myocardial Infarction
To evaluate whether remote ischemic per-conditioning (RIPC) can reduce infarct size in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention (PPCI) within 12 hours of…
- Trial name
- CAPRI (NCT02164695)
- Testing
- PPCI plus RIPC, PPCI only
- Where
- South Korea
- Volunteers
- 118 people
- Sponsor
- Yonsei University
Coronary Artery Disease
Randomized Trial of Creatine-kinase Leak After Rosuvastatin At the Time of Percutaneous Coronary Intervention
Patients with stable coronary disease when undergoing percutaneous coronary intervention may present periprocedural myocardial infarction defined at present as a creatine kinase-myocardial isoenzyme (CK-MB) elevation 3 times…
- Trial name
- CLEAR-PCI (NCT01968577)
- Testing
- Rosuvastatin
- Where
- Brazil
- Volunteers
- 528 people
- Sponsor
- Kleber Bomfim Araujo Martins
Anterior STEMI
The RECOVERY Study: Using Supersaturated Oxygen Therapy To Treat Small Vessel Blockages After a Heart Attack
The study tests whether adding supersaturated oxygen (SSO₂) therapy to standard stent treatment can improve heart recovery after a major heart attack (anterior STEMI).
- Trial name
- NCT07000266
- Testing
- Percutaneous Coronary Intervention (PCI), Diagnostic Imaging, Device Treatment
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundacio Privada Mon Clinic Barcelona
Atherosclerosis, Coronary Artery Disease
XIENCE V® EXCEED: Evaluation of XIENCE V® Catheterization Lab Endpoints and Excellence in Delivery
This trial is to assess physician-determined XIENCE V® EECSS acute performance, deliverability and resource utilization in the catheterization lab during commercial use by various physicians with a range of coronary stenting…
- Trial name
- EXCEED (NCT00731237)
- Where
- 44 sites in United States
- Volunteers
- 2,517 people
- Sponsor
- Abbott Medical Devices
Platelet Reactivity
Ticagrelor Loading Dose Versus Clopidogrel Loading and Reloading With Ticagrelor.
In the PLATO substudy referring to patients presenting with an ST-elevation Myocardial Infarction(STEMI), out of the 4201 who received ticagrelor, 1326 had been pre-treated with a 600mg clopidogrel loading dose (LD) within 24…
- Trial name
- NCT01961856
- Testing
- Clopidogrel and Ticagrelor, Ticagrelor
- Where
- Greece
- Volunteers
- 74 people
- Sponsor
- University of Patras
ST Elevation Myocardial Infarction
Remote Ischemic Conditioning With Local Ischemic Postconditioning in High-Risk ST-elevation Myocardial Infarction
The RIP-HIGH trial is a two-arm randomized controlled trial aiming to compare the impact of combined remote ischemic conditioning (RIP) and local ischemic postconditioning (PostC) vs.
- Trial name
- RIP-HIGH (NCT04844931)
- Testing
- RIC + PostC + Standard PCI, Standard PCI
- Where
- 11 sites in Austria, Germany
- Volunteers
- 250 people
- Sponsor
- Helios Health Institute GmbH
Angioplasty, Transluminal, Percutaneous Coronary
Efficacy Study of Cilostazol Loading in Elective Percutaneous Coronary Intervention
The purpose of this study is to investigate the effect of cilostazol loading before planned PCI on major adverse cardiac and cerebrovascular events in patients with coronary artery disease.
- Trial name
- PRECEDE (NCT00938522)
- Testing
- Cilostazol
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Samsung Medical Center
Left Main Coronary Artery Disease With Acute Coronary Syndrome
Study of Percutaneous Coronary Intervention in Left Main Coronary Artery Disease in Patients With Acute Coronary Syndrome at Sohag University Hospitals
Acute coronary syndromes (ACS) encompass a spectrum of cardiovascular disorders characterized by the sudden onset of myocardial ischemia.
- Trial name
- NCT06328322
- Testing
- Percutaneous Coronary Intervention in Left Main Artery Disease
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Percutaneous Coronary Intervention
Fentanyl and Crushed Ticagrelor in Percutaneous Coronary Intervention
During a percutaneous coronary intervention (PCI), Fentanyl is commonly used for sedation. Ticagrelor is also routinely used as anti-platelet agent during PCI.
- Trial name
- FACTPCI (NCT03476369)
- Testing
- Fentanyl, Ticagrelor 90Mg Tablet
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Guthrie Clinic
Acute Myocardial Infarction
Phase II Clinical Trial to Evaluate the Benefits of Postconditioning in ST-Elevation Myocardial Infarction (STEMI)
This study will evaluate change in heart muscle function from baseline to three months and twelve months in participants who present with a heart attack and a completely occluded coronary artery.
- Trial name
- NCT01324453
- Testing
- Post Conditioning + Primary PCI, Standard Primary PCI
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Minneapolis Heart Institute Foundation
Coronary Artery Disease
MIDCAB Versus DES in Proximal LAD Lesions
Percutaneous coronary intervention with a sirolimus-coated stent compared to minimally invasive bypass surgery in patients with isolated proximal left anterior descending coronary arteries in terms of non-inferiority of an end…
- Trial name
- NCT00299429
- Testing
- Stenting and minimally invasive bypass surgery, PCI with DES
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- University of Leipzig
Target Vessel Failure in Saphenous Vein Grafts, Percutaneous Coronary Intervention
Native Coronary Artery Instead of SAphenous Vein Graft Intervention for Treatment of Significant Saphenous Vein Graft Lesions
The primary study objective of the NASA registry is to evaluate the 12-month incidence of target vessel failure (TVF) in patients who present with saphenous vein graft (SVG) lesions and undergo percutaneous coronary intervention…
- Trial name
- NCT05187351
- Testing
- Percutaneous coronary intervention of the native coronary artery with Synergy
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- Minneapolis Heart Institute Foundation
Acute ST Segment Elevation Myocardial Infarction
Safety and Efficacy of Percutaneous Coronary Intervention Combined With Thrombolysis at Different Time
Patients with acute ST-segment elevation myocardial infarction and thrombolysis indications, will be given the recombinant human prourokinase for thrombolysis treatment, and in accordance with the guidelines, will be treated with…
- Trial name
- SEPCIT (NCT03137212)
- Testing
- thrombolysis and PCI of A type, thrombolysis and PCI of B type
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Hospital of Jilin University
Acute ST-segment Elevation Myocardial Infarction, Radial Artery Occlusion
Distal Transradial Access for Primary Percutaneous Coronary Intervention in STEMI Patients
The transradial access (TRA) is currently the preferred approach for percutaneous coronary intervention (PCI). However, in patients with ACUTE ST-segment elevation myocardial infarction (STEMI) after emergency PCI, the high…
- Conditions
- Acute ST-segment Elevation Myocardial Infarction, Radial Artery Occlusion, Distal Radial Artery Approach
- Trial name
- RESERVE (NCT04861389)
- Testing
- Arterial access
- Where
- China
- Volunteers
- 414 people
- Sponsor
- Shenzhen People's Hospital
Acute Coronary Syndrome
A Study to Evaluate the Safety of 12 Weeks of Dosing With GW856553 and Its Effects on Inflammatory Markers, Infarct Size, and Cardiac Function in Subjects With Myocardial Infarction Without ST-segment Elevation
This is a randomized, double-blind, placebo-controlled, parallel group, multi-center study to evaluate initial safety and efficacy of GW856553 in subjects with NSTEMI.
- Trial name
- Solstice (NCT00910962)
- Testing
- GW856553
- Where
- 108 sites in United States, Australia and 7 more
- Volunteers
- 526 people
- Sponsor
- GlaxoSmithKline
Percutaneous Coronary Intervention, Anxiety
The Effect of Listening to Music and Stress Ball Application on Patients' Anxiety Level and Hemodynamic Parameters During PCI
In this study, it was aimed to determine the effects of listening to music and applying a stress ball on patients' anxiety level and hemodynamic parameters during percutaneous coronary intervention (PCI).
- Conditions
- Percutaneous Coronary Intervention, Anxiety, Hemodynamics
- Trial name
- NCT05514574
- Testing
- Music, Stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 183 people
- Sponsor
- Keriman Yildiz
Contrast Induced Nephropathy
Contrast Medium Volume and Contrast-induced Nephropathy After Percutaneous Coronary Intervention
To investigate the predictive value of the contrast media volume to creatinine clearance (V/CrCl) ratio for the risk of contrast-induced nephropathy (CIN) (i.e., within 48-72 h) and to determine a relatively safe V/CrCl cut-off…
- Trial name
- CONVIN (NCT01399203)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Guangdong Provincial People's Hospital