Clinical trials: Perforation of the Colon
Gastric Ulcer With Perforation But Without Obstruction, Colon Cancer
Domestic Surgical Robot Clinical Study
Central South University in collaboration with Tianjin University developed the first domestically produced Chinese minimally invasive surgical (MIS) robot system which named "Micro Hand S" in 2013.
- Conditions
- Gastric Ulcer With Perforation But Without Obstruction, Colon Cancer, Cholecystolithiasis, Appendicitis
- Trial name
- NCT02752698
- Testing
- Micro Hand S robotic surgery, laparoscopic surgery, da Vinci robotic surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Colon Perforation
Feasibility and Effects of an Enhanced Recovery vs Conventional Care After Emergency Colon Surgery for Patients With Left Colon Perforation.
A study was designed with a prospective cohort of all patients undergoing urgent surgery for left colon perforation between March 2014 and June 2017 who were treated according to a specific ERAS programme (ERAS group/29…
- Trial name
- NCT03611413
- Testing
- ERAS care
- Volunteers
- 50 people
- Sponsor
- Antonio Arroyo Sebastian
Surgery, Diverticulitis
Hartmann's Versus Primary Anastomosis in Left-sided Colon Perforation
The purpose of this multi-center randomized trial is to identify any differences in the complication rates of patients undergoing Hartmann's (end colostomy) versus Primary Anastomosis (with defunctioning ileostomy) for left-sided…
- Conditions
- Surgery, Diverticulitis, Neoplasms, Postoperative Complications
- Trial name
- ColonPerfRCT (NCT01233713)
- Testing
- Hartmann's operation, Primary anastomosis
- Where
- 4 sites in Switzerland
- Volunteers
- 62 people
- Sponsor
- University of Zurich
Perforated Diverticulitis
The Damage Control Strategy for the Treatment of Perforated Diverticulitis of the Sigmoid Colon With Diffuse Peritonitis
The best approach for the treatment of perforated diverticulitis of the sigmoid colon is still under debate. Concurrent techniques are 1) resection with primary colorectal anastomosis with or without additional loop ileostomy; 2)…
- Trial name
- NCT04220840
- Testing
- Damage control strategy
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- Städtisches Klinikum München GmbH
Hemostasis, Perforation Colon
MANTIS Endoscopic Clipping Study
This study is intended to document procedural and clinical effectiveness in consecutive cases in which at least one MANTIS clip is selected, pertaining to use of a new endoscopic clipping device MANTIS™ including but not limited…
- Conditions
- Hemostasis, Perforation Colon, Feeding Tube Complication, Endoscopy
- Trial name
- NCT05653843
- Testing
- Endoscopic clip placement in the gastrointestinal tract.
- Where
- 10 sites in United States, Canada and 4 more
- Volunteers
- 240 people
- Sponsor
- Boston Scientific Corporation
Colorectal Neoplasms, Perforation of Rectum
Outcomes of Perforation After Colorectal Endoscopic Submucosal Dissection
Endoscopic resection of superficial colorectal neoplasms decrease risk of colorectal cancer. En bloc resection is necessary for large superficial lesions with risk of superficial submucosal cancer and is advised if feasible for…
- Conditions
- Colorectal Neoplasms, Perforation of Rectum, Perforation Colon
- Trial name
- NCT05728710
- Testing
- Endoscopic submucosal dissection
- Where
- 13 sites in Belgium, France
- Volunteers
- 350 people
- Sponsor
- Central Hospital, Nancy, France
Intestinal Perforation
Evaluation of the Ability to Detect Bowel Gas During Laparoscopic Surgery
This study will determine the ability of the device to draw a small amount of gas from an insufflated abdomen during laparoscopic surgery and accurately detect if gaseous content from the bowel is present.
- Trial name
- NCT02679118
- Testing
- Sentire
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Dan E. Azagury
Advanced Colorectal Cancer in Elderly Patient
The Management of Complicated Colo-rectal Cancer in Older Patients in the Emergency Setting: the CO-OLDER Study
This is a multicenter observational study aimed to investigate the management of older patients aged 75 years old and over admitted to the emergency department with complicated colorectal cancer.
- Trial name
- CO-OLDER (NCT05788224)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Poissy-Saint Germain Hospital
Abdominal Sepsis, Peritonitis
Impact of Early Peri-operative Use of Polymyxin-B Hemoperfusion in Septic Patients Undergoing Emergent Abdominal Surgery
Septic shock of intra-abdominal origin is likely due to Gram-negative bacteria or mixed pathogens and associated with high levels of endotoxin.
- Conditions
- Abdominal Sepsis, Peritonitis, Colon Perforation
- Trial name
- NCT01646229
- Testing
- Polymyxin-B hemoperfusion, Control
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University Hospital, Geneva
Colon Neoplasm, Rectum Neoplasm
Ultrasound Guided Transversus Abdominis Plane(TAP) Block in Intensive Care Unit
The Transversus Abdominis Block (TAP) block is known to be an effective means of reducing patient pain after abdominal surgery. In the meantime, the general TAP block has been studied in patients who were in the recovery room and…
- Conditions
- Colon Neoplasm, Rectum Neoplasm, Perforated Colon, Perforated Bowel
- Trial name
- NCT03198338
- Testing
- 0.25% Bupivacaine, 0.5mL/kg, Normal Saline, Ultrasound
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Seoul National University Bundang Hospital
Intestinal Atresia, Necrotizing Enterocolitis
The Role of Indocyanine Green Angiography Fluorescence on Intestinal Resections in Pediatric Surgery.
Background: Intestinal resections are commonly performed in the pediatric population. Perfusion of the bowel is one of the most important factors determining the viability of an intestinal anastomosis.
- Conditions
- Intestinal Atresia, Necrotizing Enterocolitis, Hirschsprung Disease, Gastroschisis
- Trial name
- NCT04020939
- Testing
- SPY imaging, Indocyanine Green
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Rectal Foreign Body, Rectal Perforation
Management and Removal of Foreign Bodies in the Emergency Department
Management of rectal foreign bodies presents unique challenges in the emergency department. Rectal foreign bodies may consist of various compositional materials and ergonomics which include but are not limited to vegetables…
- Conditions
- Rectal Foreign Body, Rectal Perforation, Colonic Perforation
- Trial name
- NCT05888363
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Arrowhead Regional Medical Center
Colorectal Cancer
Impact of PET Scan on the Curative Strategy of Colo-rectal Cancers : A Randomized Study
The risk of recurrence in stage III and IV of colorectal cancers (CRC) is high during the three years following the tumoral resection with curative aim.
- Trial name
- ITEP (NCT00624260)
- Testing
- semi-annual systematic PET-TDM, PET-TDM for current indication
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Perforation Colon
Incidence and Clinical Course of Colonoscopy Related Perforation
This study aims to investigate the incidence and clinical course of colonoscopy related perforation based on the result of a prospective registry.
- Trial name
- NCT03833856
- Testing
- colonoscopy perforation
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Kyungpook National University Hospital
Perforation of the Oesophagus, Perforation of the Colon
VAC-Stent Registry
This registry is intended to collect data on quality assurance and use of the VAC-Stent® and thus verify the suitability of the VAC-Stent® for sealing leakages in the oesophagus or colon.
- Trial name
- NCT04884334
- Testing
- VAC-Stent®
- Where
- 14 sites in Germany
- Volunteers
- 110 people
- Sponsor
- Markus M. Heiss
GI Bleeding, Perforation Colon
Evaluation of the Clinical Utility of Endoscopic Closure Using a Dual Action Tissue (DAT) Clip
This study is designed as a multicenter prospective data recording study to document the performance of the DAT clip as part of standard medical care of patients. No experimental interventions will be performed.
- Conditions
- GI Bleeding, Perforation Colon, Perforation Bowel, Perforation Duodenal
- Trial name
- NCT05852457
- Testing
- DAT Clip
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- AdventHealth
Hirschsprung Disease, Bowel; Perforation, Fetus or Newborn
Risk Factors of Perforated HSCR in Neonates
Hirschsprung's disease (HSCR) is a common digestive malformation with radiographic evidence of distal bowel obstruction and clinical signs of abdominal distension, vomiting, constipation, and failure to pass meconium.
- Trial name
- NCT05044741
- Testing
- Emergency surgical enterostomy
- Volunteers
- 600 people
- Sponsor
- Tongji Hospital