Clinical trials: Perforator Flap
Hypotension During Surgery
Goal-directed Fluid Therapy During Deep Inferior Epigastric Perforator (DIEP) Free Flap Breast Reconstruction
Adequate free flap perfusion during Deep Inferior Epigastric Perforator (DIEP) flap breast reconstruction surgery requires maintaining blood pressure above 100 mmHg and avoiding excessive fluid administration.
- Trial name
- GDFT DIEP-flap (NCT06080178)
- Testing
- Plasma-lyte (static group), Norepinephrine (static group), Plasma-lyte (dynamic group)
- Where
- Belgium
- Volunteers
- 41 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Meningocele, Meningomyelocele
Propellers Flaps for Meningomylocele Defects
To evaluate reliability of free style propeller perforator flap for coverage MMC soft tissue defect follow a well-established step that overcome the usual problem of pedicled perforators propellers flaps.
- Trial name
- NCT05188300
- Testing
- Freestyle pedicled perforators propellers flaps for meningomyelocele defects
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Breast Cancer, Exercise
The Effect of a Post-operative Exercise Programme Versus Standard Care on Physical Fitness of Patients With Breast Cancer Undergoing Deep Inferior Epigastric Perforator (DIEP) Flap Reconstruction Surgery
All patients undergoing mastectomy for breast cancer should be offered the option of reconstructive surgery. The Deep Inferior Epigastric Perforator Flap or DIEP reconstruction as it is commonly referred to, is becoming the…
- Trial name
- EXERCISE DIEP (NCT07672392)
- Testing
- Structured individualised 12-week post operative exercise programme
- Where
- Ireland
- Volunteers
- 78 people
- Sponsor
- Royal College of Surgeons, Ireland
Postoperative Pain
Rhomboid Intercostal Block Versus Serratus Anterior Plane Block
evaluate and compare the impact of ultrasound guided rhomboid intercostal block versus serratus anterior plane block for analgesia after thoracodorsal artery perforator flap following partial mastectomy
- Trial name
- NCT05661279
- Testing
- general anesthesia, general anesthesia plus Rhomboid intercostal block, Serratus anterior plane block
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Microvascular Free Flap Transfer, Fibula Flap
Artificial Intelligence-Enabled Skin Perforator Segmentation
Computer-assisted surgery has revolutionized reconstruction with more efficient, accurate, and predictable surgery, as reported in our previous studies.
- Trial name
- NCT06634472
- Testing
- artificial intelligence
- Where
- Hong Kong
- Volunteers
- 49 people
- Sponsor
- The University of Hong Kong
Trauma Patients With Soft Tissue Defects
Posterior Tibial Artery Perforator-Pedicled Propeller Flaps in Reconstruction
Soft tissue defects in the lower leg remain a challenge for surgeons due to frequent bone exposure and paucity of soft tissues. The goal in this study was to evaluate the surgical technique and clinical significance of posterior…
- Trial name
- NCT06885892
- Testing
- Posterior Tibial Artery Perforator-Pedicled Propeller Flaps, Perforator-Pedicled Propeller Flaps
- Where
- China
- Volunteers
- 14 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Blood Vessel Perforation
Prospective Diagnostic Study on Perforator Localization of Anterolateral Thigh Flap With Perforator Locator
Oral and maxillofacial region is an important anatomical part of human body, responsible for chewing, swallowing, language, expression, breathing and other physiological functions.
- Trial name
- NCT05924984
- Testing
- perforator locator
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Ankle Tissue Injury Wound
Lateral Supramalleolar Perforator Flap Reconstruction Through Branches Outside of the Ankle Tissue Defects
The lateral ankle is a common site of tissue defects and the defects in this area are often accompanied by exposure of the fibula and tendons.
- Trial name
- NCT04687345
- Volunteers
- 15 people
- Sponsor
- National Defense Medical Center, Taiwan
Deep Inferior Epigastric Artery Perforator Flap Breast Reconstruction
The Effect of Volatile Anesthesia and Total Intravenous Anesthesia on Shedding of the Endothelial Glycocalyx in Patients Undergoing Mastectomy and Breast Reconstruction Using Deep Inferior Epigastric Artery Perforator Free Flap
The aim of this study was to investigate the effects of total intravenous and inhalation anesthesia on the damage of endothelial glucocorticoids by comparing the concentration of syndecan-1 in patients undergoing mastectomy and…
- Trial name
- NCT05136508
- Testing
- Propofol, Sevoflurane
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Breast Neoplasms, Ischemia-Reperfusion Injury
DIEP Flap Breast Reconstruction: Perioperative Biomarkers and Outcomes
Brief Summary This observational study will follow patients who undergo DIEP flap breast reconstruction to better understand a common surgical challenge called ischemia-reperfusion (I/R) injury.
- Conditions
- Breast Neoplasms, Ischemia-Reperfusion Injury, Postoperative Complications, Wound Healing
- Trial name
- NCT07263347
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Hubei Cancer Hospital
Reconstructive Surgery
Fluorescence Angiography: Planning and Monitoring of Perforator Flaps
The purpose of this study is to determine whether fluorescence angiography is an effectiveness technique for the localization of vascular perforators and their area of perfusion and for the postoperative monitoring of flap…
- Trial name
- AFLU (NCT01681797)
- Testing
- Fluorescence angiography (Fluobeam™ imaging system developed by Fluoptics company)
- Where
- France
- Volunteers
- 27 people
- Sponsor
- University Hospital, Grenoble
Breast Neoplasms, Mammaplasty
ARTISS a Single-centre Randomised Control Study
The Influence of ARTISS on post-operative abdominal drainage and seroma formation in DIEP/MS-TRAM free flap breast reconstruction patients.
- Trial name
- ARTISS (NCT04931615)
- Testing
- ARTISS 4mL Fibrin Sealant Topical Solution (Frozen), no ARTISS
- Where
- United Kingdom
- Volunteers
- 135 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
Reconstructive Surgical Procedures
DIEP Flap Perfusion Evaluated by DIRT and ICG-FA.
Patients selected for DIEP breast reconstruction were examined with preoperative CTA, Doppler Ultrasound, dynamic infrared thermography (DIRT) and Indocyanin green fluorescent angiography (ICG-FA) for perforator mapping.
- Trial name
- NCT04115995
- Testing
- Dynamic infrared thermography (DIRT) and indocyanine green fluorescence angiography (ICG-FA)
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Reconstructive Surgery, Microcirculation
Microcirculation in Perforator Flaps. Enhancing Tissue Survival
The aim of the present study is to assess the microcirculatory changes in the distal part of the perforator flap using ICG fluorescence angiography.
- Trial name
- NCT01204554
- Testing
- Indocyanine green (ICG)
- Where
- Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Scar, Contracture
Perforator Artery Changes During Suprafascial Pre-expansion of the Perforator Flaps
Tissue expansion methods have been recommended as a means of improving the clinical results with perforator flaps but in plastic surgery literature there are few clinical trials supporting this opinion.
- Conditions
- Scar, Contracture, Flap Disorder
- Trial name
- NCT01777386
- Testing
- preexpanded perforator flap surgery
- Volunteers
- 14 people
- Sponsor
- Istanbul University
Breast Cancer, Postsurgical Acquired Absence of Organ
Non-contrast Magnetic Resonance Angiography in Deep Inferior Epigastric Perforator Flap Breast Reconstruction Planning
The aim of this study is to evaluate the efficacy and safety of contrast-free magnetic resonance angiography (MRA) for deep inferior epigastric perforator flap planning.
- Trial name
- NCT06061835
- Testing
- Non-contrast MRA in preoperative perforator vessels mapping for deep inferior epigastric perforator (DIEP) flap breast reconstruction planning., CTA with iodine contrast in preoperative perforator vessels mapping for deep inferior epigastric perforator (DIEP) flap breast reconstruction planning.
- Where
- 2 sites in Russia
- Volunteers
- 135 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Breast Ptosis
Breast Reshaping Following Massive Weight Loss
Reliability of Chest Wall Perforator Flaps for Breast Reshaping following Massive Weight Loss
- Trial name
- NCT06262724
- Testing
- Breast auto-augmentation
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Myelomeningocele
Role of Perforator Flaps in Back Defects Reconstruction
evaluation of perforator flaps versus perforator plus flaps
- Trial name
- NCT06405698
- Testing
- surgical closure of myelomeningocele defects by perforator flaps, surgical closure of myelomeningocele defects by perforator-plus flaps
- Volunteers
- 30 people
- Sponsor
- Assiut University
Deep Inferior Epigastric Perforator Flap Reconstruction
Case Series Comparing Drains to TissuGlu® in a Donor Site DIEP Flap Breast Reconstruction Procedure
To evaluate the safety and effectiveness of a lysine-derived urethane adhesive (TissuGlu® Surgical Adhesive) as a less invasive alternative to surgical drains in the abdominal donor site for deep inferior epigastric perforator…
- Trial name
- NCT03481140
- Testing
- TissuGlu Surgical Adhesive
- Volunteers
- 58 people
- Sponsor
- Cohera Medical, Inc.
Upper Aero-intestinal Tract Cancer, Supraclavicular Flap
Anterior Thoracic Perforating Artery (PATA); Systematization and Applications in Reconstructive Surgery of the Head and Neck
The use of cutaneous or fasciocutaneous flaps is daily in reconstructive surgery ENT in patients with cancers of the upper aero-digestive tract (AVDS).
- Conditions
- Upper Aero-intestinal Tract Cancer, Supraclavicular Flap, Anterior Thoracic Perforator Artery
- Trial name
- PATA-Fix (NCT06140160)
- Testing
- Doppler ultrasound
- Where
- France
- Volunteers
- 75 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche