Clinical trials: Perforator Flap
Sensitisation
DIEP (Deep Inferior Epigastric Artery Perforator) Flap Sensory Recovery Following Neurotization
The purpose of this study is to compare the sensory return of DIEP flaps with nerve connection to DIEP flaps with no nerve connection to see which is better.
- Trial name
- NCT04818190
- Testing
- Sensory neurotization
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Breast Cancer, Vascularization
Fluorescence Angiography in the Assessment of DIEP Flap Perfusion
It is a single-center, prospective, randomized and controlled study focused in microsurgical autologous breast reconstruction. It involves applying indocyanine green (ICG) angiography for the study of the vascularization of DIEP…
- Conditions
- Breast Cancer, Vascularization, Fat Necrosis
- Trial name
- NCT02759796
- Testing
- Tailoring the flap according to clinical assessment, Tailoring the flap according to ICG Angiography assessment
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Breast Cancer
Impact of Radiotherapy on Patients Undergoing DIEP Flap Breast Reconstruction
The investigators intend to undertake a study to investigate the effect of radiotherapy on deep inferior epigastric perforator flap reconstructions (DIEP).
- Trial name
- NCT03072316
- Testing
- 3D surface imaging, semi-structured interview, applanation tonometry
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Breast Cancer
Outcomes of a Deep Inferior Epigastric Perforator Flap Program
The purpose of this study is to analyze an institution's experience with starting a subspecialized DIEP flap program.
- Trial name
- NCT00543907
- Where
- United States
- Volunteers
- 977 people
- Sponsor
- Beth Israel Deaconess Medical Center
Reconstructive Surgery Using Pedicled Perforating or Free Perforating Flaps, Pelvic Eschar
Study and Modeling of Perforator Flap Vascularization
The aim of reconstructive surgery is to restore physical integrity altered by trauma, congenital malformations or cancerous pathologies.
- Conditions
- Reconstructive Surgery Using Pedicled Perforating or Free Perforating Flaps, Pelvic Eschar, Traumatic Pathology of the Lower and/or Upper Limb
- Trial name
- EMoVaLP (NCT07084740)
- Testing
- PeriCam and PeriFlux measurements
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Soft Tissue Defects, Perforator Flap
Perforator Pedicled V-Y Advanced Flaps for Coverage in the Lower Limbs
Repair of soft tissue defects with hardware exposing in the lower limbs was considered as a severe challenge for plastic surgeons in reconstructive surgery.
- Trial name
- NCT06885450
- Testing
- Perforator Pedicled Flaps
- Where
- China
- Volunteers
- 24 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Breast Reconstruction, Breast Cancer
Comparison of PEAK PlasmaBlade™ to Conventional Diathermy in Abdominal Based Free Flap Breast Reconstruction
Electrosurgery allows for dissection with simultaneous haemostasis. One of its disadvantages is that the heat production can cause injury to the surrounding tissue which may result in wound healing problems and an increased rate…
- Trial name
- NCT04350411
- Testing
- Conventional diathermy, PEAK PlasmaBlade™
- Where
- United Kingdom
- Volunteers
- 108 people
- Sponsor
- Anglia Ruskin University
Pain, Postoperative
Comparison of Local Anesthetic Infusion Pump Versus Depofoam Bupivacaine for Pain Management
Effective post surgical pain control in patients undergoing unilateral deep inferior epigastric perforator (DIEP) free flap reconstruction.
- Trial name
- NCT04284930
- Testing
- Depobupivacaine, OnQ pump, 0.25% Bupivacaine
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The Cleveland Clinic
Breast Cancer
Nerve Coaptation in LTP Flap Breast Reconstruction
The sensory recovery of the breast remains an undervalued aspect of breast reconstruction and surgical reinnervation is not regarded as a priority by most reconstructive surgeons.
- Trial name
- NCT03959943
- Testing
- Sensory nerve coaptation
- Where
- Netherlands
- Volunteers
- 46 people
- Sponsor
- Maastricht University Medical Center
Stage II Cutaneous Melanoma
COmparison of the Use of a PERforator Flap Versus Total Skin GRAft in the Management of Loss of Substance After Resection of Cutaneous Melanoma - Pilot Study
Melanoma is an aggressive and potentially fatal skin cancer and was the fifth most commonly diagnosed cancer among both men and women in the United States in 2022.
- Trial name
- COPERGRAM1 (NCT07354152)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Nantes University Hospital
Perforator Flap Surgery
Comprehensive Imaging of Perforator Vessels and Subcutaneous Vascular Network With No-Exogenous Contrast and Non-Ionizing-Radiation Magnetic Resonance Angiography
In this study the investigators plan to enroll a total of 25 evaluable volunteers (volunteer population) for the development and optimization of perforator imaging protocols and 50 evaluable clinical patients receiving flap…
- Trial name
- NCT03567018
- Testing
- MRI Scan
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Soft Tissue Defect
Clinical Experience With a Tensor Fasciae Latae Perforator Flap Based on Septocutaneous Perforators
The purpose of this study is to evaluate the possible harvest of a tensor fasciae latae flap based on septocutaneous perforators.This study should further confirm our data from an anatomical study concerning location…
- Trial name
- NCT01136044
- Testing
- septocutaneous perforator flap
- Where
- Austria
- Volunteers
- 14 people
- Sponsor
- Medical University of Graz
Breast Reconstruction
Pre-Operative Imaging of Abdominal Wall Perforators Using CT Angiography
Abdominal donor-site flaps, including the transverse rectus abdominis musculocutaneous (TRAM) and deep inferior epigastric artery perforator flaps(DIEP), are standard in autologous breast reconstruction.
- Trial name
- DIEP (NCT00748722)
- Testing
- CT Angiography
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Breast Cancer
CT-Angiography Prior to DIEP Flap Breast Reconstruction
This study will Investigate whether or not preoperative computed tomography (CT) angiography will lower operative times and post operative complications for breast reconstruction performed with a deep inferior epigastric artery…
- Trial name
- NCT02883387
- Testing
- Preoperative CT angiography, No Preoperative Imaging
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Colorado, Denver
Breast Reconstruction
Impact of Drainless Donor Abdominal Site in Deep Inferior Epigastric Perforator (DIEP) Flap on Complications and Duration of Hospital Stay.
Inserting surgical drains is an ancient approach used across different specialties because of its many advantages such as discharge of fluid accumulation, appraising and qualifying drain capacities, lowering infection…
- Trial name
- NCT06468488
- Testing
- DIEP flap surgery without drain, DIEP flap surgery with drains
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Axillary Hidradenitis Suppurativa
Perforator Flaps for Axillary Hidradenitis Suppurativa
Hidradenitis Suppurativa (HS) is a recurrent inflammatory disease (< 2 episode /6 months) with 1%-4% prevalence in Europe. Suppurating lesions are painful and involve one or more regions (axilla, genitofemoral, perineum, gluteal…
- Trial name
- HS-PAX (NCT03784313)
- Testing
- skin repair by axillary perforator flaps, skin repair by secondary wound healing
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Reconstruction of Upper Body Soft Tissue Defects
Reconstruction by Thoracodorsal Artery Perforator Flap in Patients With Upper Body Soft Tissue Defects
evaluation of versatility and reliability of thoracodorsal artery perforator flap by assessment of recipient site reach
- Trial name
- NCT07734337
- Testing
- Reconstruction
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Breast Reconstruction
Negative Pressure in PAP Donor Sites
A retrospective chart review will be conducted to identify patients who received breast reconstruction using free profunda artery perforator (PAP) flap by the investigators from January 2015 to August 2021.
- Trial name
- NCT05491473
- Testing
- Closed incisional negative pressure wound therapy (iNPWT) system
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Chang Gung Memorial Hospital
Breast Cancer, Acquired Absence of Breast
Long-term Evaluation of Quality of Life and Aesthetic Outcomes After Autologous Breast Reconstruction Using the Profunda Artery Perforator (PAP) Flap
Breast reconstruction using autologous tissue is an important option for women undergoing mastectomy for breast cancer. The profunda artery perforator (PAP) flap is a reliable alternative when abdominal tissue is unavailable or…
- Conditions
- Breast Cancer, Acquired Absence of Breast, Autologous Breast Reconstruction
- Trial name
- QUALIPAP (NCT07728565)
- Where
- France
- Volunteers
- 264 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Reconstruction, Skin Perfusion
Microcirculation of the Abdominal Skin After Deep Inferior Epigastric Artery Perforator Flap Procedure
The purpose of this study was to perform a quantitative perfusion study of the undermined abdominal skin in deep inferior epigastric artery perforator flap breast reconstruction patients in order to obtain more knowledge on…
- Trial name
- NCT02481284
- Testing
- Laser Doppler perfusion imaging
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital