Clinical trials: Perforator Flap
Breast Cancer, Hereditary Breast/Ovarian Cancer (brca1, brca2)
Outcomes After Perforator Flap Reconstruction for Breast Reconstruction and/or Lymphedema Treatment
The goal of this prospective, observational study is to investigate the clinical, psychosocial, and patient satisfaction outcomes of patients who undergo perforator flap reconstruction for breast reconstruction and/or…
- Conditions
- Breast Cancer, Hereditary Breast/Ovarian Cancer (brca1, brca2), Acquired Lymphedema, Congenital Lymphedema
- Trial name
- NCT01273909
- Testing
- Perforator Flap Breast Reconstruction, Vascularized Lymph Node Transfer
- Where
- 3 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- The National Institute of Lymphology
Pilonidal Disease
Excision and Reconstruction of the Natal Cleft With a Parasacral Perforator Flap Versus Open Excision With Secondary Healing, in the Management of Sacrococcygeal Pilonidal Disease.
Chronic sacrococcygeal pilonidal disease is a common acquired condition associated with hirsutism that predominantly affects young male patients.
- Trial name
- PILOPERFO (NCT03534700)
- Testing
- parasacral flap reconstruction, open excision
- Where
- 2 sites in France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Toulouse
Breast Cancer, Perforator Flap
Deep Inferior Epigastric Artery Flap for Breast Reconstruction
Background: There is no consensus on the duration of prophylactic antibiotics for autologous breast reconstruction after mastectomy.
- Conditions
- Breast Cancer, Perforator Flap, Anti-Infectives Adverse Reaction, Infections
- Trial name
- NCT05088239
- Testing
- prophylactic antibiotics duration
- Volunteers
- 108 people
- Sponsor
- Chiayi Christian Hospital
Post Traumatic Skin Defect in Leg and Foot
Use of Perforator Flaps for Leg and Foot Reconstruction
Perforator vessels are those where the source artery is deep and the branch that carries blood to the fasciocutaneous tissues passes through the overlying deep fascia.
- Trial name
- NCT03269864
- Testing
- perforator flaps
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Blood Vessel Perforation
Exploratory Study on the Application of Virtual Augmented Reality Combined With Finder in Preoperative Anterolateral Thigh Flap Perforator Positioning
Oral and maxillofacial region is an important anatomical part of human body, responsible for chewing, swallowing, language, expression, breathing and other physiological functions.
- Trial name
- NCT06277687
- Testing
- Virtual Augmented Reality Combined With Finder
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Pilonidal Sinus Treatment
The Outcomes of Keystone Perforator Island Flap Versus Lay Open in Re-recurrent Pilonidal Sinus Disease
Pilonidal disease is a common and annoying problem with a fair recurrence rate. Every time of recurrence more skin is needed to cover the defect and if left open healing is supposed to be prolonged.
- Trial name
- NCT06741449
- Testing
- keystone flap, lay open
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Zagazig University
Breast Tumor, Perforator Flap
Outcomes of Local Perforator Flaps in Oncoplastic Surgery
This is a single center experience of using local perforator flaps in partial breast reconstruction for breast tumors while evaluating cosmetic outcomes, patient satisfaction and well-being using a validated self-administered…
- Conditions
- Breast Tumor, Perforator Flap, Breast Cancer, Oncoplasty
- Trial name
- NCT05389605
- Testing
- No intervention was undertaken
- Where
- Pakistan
- Volunteers
- 25 people
- Sponsor
- Aga Khan University
Failed Carpal Tunnel Syndrome Surgery
Treatment of Failed Carpal Tunnel Syndrome by Dorsal Ulnar Artery Perforator Adipofascial Flap
Carpal tunnel syndrome (CTS) is the most common compressive neuropathy in the general population. Surgical treatment by open or endoscopic carpal tunnel release (CTR) is the first choice of treatment and has clinical success…
- Trial name
- NCT06324617
- Testing
- Treatment of failed carpal tunnel syndrome by dorsal ulnar artery perforator adipofascial flap
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Oral Cavity Defect, Oropharynx Defect
Reinnervated PAP Flap for Oral Cavity and Oropharyngeal Defect Reconstruction
The aim of this study is to investigate sensory recovery and functional outcomes following oral cavity and oropharyngeal defect reconstruction with reinnervated PAP (profunda artery perforator) flaps.
- Trial name
- NCT05997186
- Testing
- Surgical reconstruction
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University Hospital, Basel, Switzerland
Deep Inferior Epigastric Perforator Flap Breast Reconstruction
TAP vs QL Block for DIEP Flap Breast Reconstruction
The purpose of this two-arm clinical study is to compare two nerve block techniques, the transversus abdominis plane (TAP) block and the quadratus lumborum (QL) block, in terms of how well they manage pain in the immediate…
- Trial name
- NCT06962150
- Testing
- Surgeon-placed transversus abdominis plane block, Ultrasound-guided quadratus lumborum block
- Sponsor
- Yale University
Breast Reconstruction, Abdominal Wall Morbidity
Changes To The Abdominal Wall After DIEP Flap Breast Reconstruction
The purpose of this study was to perform an evaluation of the structural changes in the abdominal wall after harvesting a DIEP flap in breast reconstruction.
- Trial name
- NCT02563977
- Testing
- 2 year postop CT scan of the abdomen
- Where
- Norway
- Volunteers
- 14 people
- Sponsor
- Oslo University Hospital
Contractures, Scars
Preexpanded Perforator Flaps in Children
Contractures and broad scars of the axilla, anterior chest wall and neck have detrimental effects on functional, physical and psychological development of children.
- Trial name
- NCT01700595
- Testing
- new technical intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 7 people
- Sponsor
- Istanbul University
Ductal Breast Carcinoma in Situ, Lobular Breast Carcinoma in Situ
Stereotactic Image-Guided Navigation During Breast Reconstruction in Patients With Breast Cancer
Many hospitals, including the Ohio State University Medical Center, will take pictures of the blood vessels in a patient's abdomen before they decide to perform a breast reconstruction using the patient's own tissue.
- Conditions
- Ductal Breast Carcinoma in Situ, Lobular Breast Carcinoma in Situ, Recurrent Breast Cancer, Stage IA Breast Cancer
- Trial name
- NCT01729832
- Testing
- breast reconstruction, intraoperative imaging
- Sponsor
- Ohio State University Comprehensive Cancer Center
Breast Cancer
Lateral Thigh Perforator (LTP) Flap for Autologous Breast Reconstruction
The lateral thigh perforator (LTP) flap was previously introduced as an alternative flap for autologous breast reconstruction when the abdomen is not suitable as a donor site.
- Trial name
- NCT03106233
- Testing
- LTP flap
- Where
- Netherlands
- Volunteers
- 86 people
- Sponsor
- Maastricht University Medical Center
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Carcinoma
PARTial BREast RECONstruction With Chest Wall Perforator Flap
The goal of this observational study is to ascertain the outcomes following partial breast reconstruction using chest wall perforator flaps after breast conservation surgery.
- Conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Carcinoma, Breast Neoplasms, Breast Surgery
- Trial name
- PartBreCon (NCT06728527)
- Where
- United Kingdom
- Volunteers
- 1,001 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Cancer
Comparison of Harmonic Scalpel to Conventional Diathermy in Perforator Flap Elevation for Head and Neck Reconstruction
This study is to compare the efficacy of Harmonic Scalpel with conventional diathermy technique in terms of reducing elevation time and perioperative complications of perforator flaps for head and neck reconstruction.
- Trial name
- NCT01092468
- Testing
- Diathermy, Harmonic Scalpel
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Arterial Hypotension
Effect of Phenylephrine Versus Norepinephrine on Venous Return
Induction of general anesthesia often induces a decrease in the mean arterial blood pressure (MAP) caused by arterial and venous dilatation.
- Trial name
- NCT03872570
- Testing
- Phenylephrine, Norepinephrine
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Coverage of Soft Tissue Defects
Perforator Mapping and Optimizing Design of the Lateral Arm Flap
The goal of this clinical trial is to optimize the design of lateral arm flap. Colored duplex will be done for all Participants and compared to intra operative findings.
- Trial name
- NCT05718635
- Testing
- coloured duplex, supra facial dissection
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aswan University
Breast Cancer
BENEFIT OF MECHANICAL ISCHEMIC PRECONDITIONING ON TOLERANCE OF ADIPOSE TISSUE TO ISCHEMIA REPERFUSION OF TYPE DIEP (DEEP INFERIOR EPIGASTRIC PERFORATOR) FREE FLAPS.
Breast cancer is the most common cancer amongst women in terms of frequency, with more than 50 000 newly diagnosed cases per year in France. The average 5-year survival rate for women with breast cancer is around 85%.
- Trial name
- PRIMIDIEP (NCT05373069)
- Testing
- Mechanical ischemic preconditioning of diep-type flap
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rectal Cancer
Effect of a Post-operative Protocol of Early Mobilization on Functional Recovery and Postoperative Complications After Immediate Internal Pudendal Artery Perforator Flap Reconstruction for Irradiated Abdominoperineal Resection Defects: a Prospective, Randomized and Controlled Clinical Study.
Major abdominal oncology surgery is associated with substantial postoperative loss of functional capacity, and exercise may be an effective intervention to improve outcomes.
- Trial name
- NCT04795609
- Testing
- Early mobilization strategy adapted after immediate internal pudendal artery perforator flap reconstruction for abdominoperineal resection (intervention group).
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo