Clinical trials: Perforator Flap
Breast Reconstruction, Deep Inferior Epigastric Perforator
The Effects of Caffeine on Deep Inferior Epigastric Perforator (DIEP) Flap Perfusion
Women that require breast reconstruction and meet eligibility will be enrolled in this study. The study is being completed to determine the effect of caffeine in deep inferior epigastric perforator (DIEP) flap perfusion using the…
- Conditions
- Breast Reconstruction, Deep Inferior Epigastric Perforator, Microvascular Free Flap Transfer
- Trial name
- NCT04249934
- Testing
- Caffeinated Coffee, DecaffeinatedCoffee
- Where
- United States
- Sponsor
- University of Michigan
Breast Reconstruction
Pain Study Using Intermittent Bupivacain Injections After Breast Reconstruction With DIEP Flap
patients are given bupivacain intermittent locally on the donor site after brest reconstruction with diep flap. The hypothesis was that this approach will reduce the need for rescue analgetic medication and pain perception within…
- Trial name
- NCT00804674
- Testing
- bupivacain
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Weight Loss
Volumetric Study of the Buttocks After Flap Augmentation in Buttocks Lifting
The development of bariatric surgery, its effectiveness and the reduction of complications are at the origin of massive weight loss, the corollary of which has been a clear increase in the demands of treatment of sequelae of…
- Trial name
- NCT03882736
- Testing
- gluteal augmentation with flap in circumferential body lift
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Breast Cancer
Influence of the Superficial Inferior Epigastric System in Deep Inferior Epigastric Perforator (DIEP) Flaps
The purpose of this study is to determine in-vivo the effects the contralateral superficial inferior epigastric vascular system has on the perfusion of Zone IV of deep inferior epigastric perforator flaps.
- Trial name
- NCT01464970
- Testing
- Both Superficial Inferior Artery and Vein Clamped, Superficial Inferior Epigastric Vessels both unclamped, SIE Artery Unclamped, Vein Clamped
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- NHS Greater Glasgow and Clyde
Breast Cancer, Oncoplastic Breast Surgery
Scarless Advanced Breast Extended Oncoplasty: The ScarABEO Study
Breast conserving surgery followed by radiotherapy is the gold standard treatment for early breast cancer. Cases with unfavorable tumor volume to breast volume ratio or challenging localizations are at higher risk of margin…
- Conditions
- Breast Cancer, Oncoplastic Breast Surgery, Oncoplastic Breast-conserving Surgery, Chest Wall Perforator Flap
- Trial name
- ScarABEO (NCT06906237)
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Istituto Oncologico Veneto IRCCS
Breast Cancer
The Effects of Indocyanine Green Angiography (IGA) on Deep Inferior Epigastric Artery Perforator (DIEP) Flap Design and Post-Operative Fat Necrosis
The aim of this study is to prospectively evaluate the effect of intra-operative Indocyanine green angiography (IGA) on both flap design and rate of post-operative fat necrosis in patients undergoing autologous breast…
- Trial name
- SPY (NCT02144961)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Perioperative Tissue Oxygenation
Improving Tissue Oxygenation in Breast Reconstruction Surgery
Breast reconstruction is an integral part of breast cancer care. There are two main types of breast reconstruction: alloplastic (using implants), and autologous (using patient's tissue).
- Trial name
- NCT04020172
- Testing
- Dobutamine
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Dr. Glenio Mizubuti (MD, PhD)
Mammoplasty Patient
Evaluation of Perforator Phase Contrast Angiography in Developing Surgery Plans for Patients With Breast Cancer Undergoing Breast Reconstruction With Free-Flap Methods After Mastectomy
This phase II trial studies how well an imaging technique called perforator phase contrast angiography (pPCA) works in developing surgery plans for patients with breast cancer undergoing breast reconstruction after breast removal…
- Trial name
- NCT04063410
- Testing
- Angiography, MRI-Based Angiogram, Quality-of-Life Assessment
- Where
- United States
- Sponsor
- University of Cincinnati
Weight Loss
Volumetric Study of the Buttocks After Flap Augmentation in Buttocks Lifting
The development of bariatric surgery, its effectiveness and the reduction of complications are at the origin of massive weight loss, the corollary of which has been a clear increase in the demands of treatment of sequelae of…
- Trial name
- NCT03777618
- Testing
- gluteal augmentation with flap in circumferential body lift
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Lip Injury
The Reliability and Versatility of Facial Artery Perforator-Based Nasolabial Flaps in The Reconstruction of Lip Defects
Nasolabial flaps have limited mobility and may need two stages, mostly for intraoral defects .The facial artery perforator-based flap is the first true perforator flap in the face.
- Trial name
- NCT04974918
- Testing
- Facial Artery Perforator-Based Nasolabial Flaps in The Reconstruction of large Lip defects post traumatic or post tumor resection.
- Volunteers
- 20 people
- Sponsor
- Sohag University
Oral Squamous Cell Carcinoma (OSCC)
Clinical Outcomes of Thoracodorsal Artery Flap in Oral and Maxillofacial Reconstruction
The goal of this study is to retrospectively compare different types of free flaps to determine the most suitable free flap for functional reconstruction in oral squamous cell carcinoma patients following tumor resection.
- Trial name
- NCT06599801
- Testing
- Thoracodorsal artery perforator flap reconstruction surgery, Forearm flaps reconstruction surgery, Anterolateral thigh flap reconstruction surgery
- Where
- China
- Volunteers
- 217 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Mammaplasty, Microsurgery
Perioperative Management of DIEP Flaps
By comparison of two different protocols with diverse fluid/ catecholamine administration limits (fluid restriction vs. catecholamine restriction with target systolic blood pressure > 100 mmHg) the investigators would like to…
- Conditions
- Mammaplasty, Microsurgery, Free Tissue Flaps
- Trial name
- NCT03118024
- Testing
- Crystalloid Solutions, Catecholamines
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Regensburg
Trauma
Thoracodorsal Artery Perforator Flap Versus Conventional Free Flaps
The purpose of this study is to assess the efficacy of the thoracodorsal artery perforator flap versus other conventional free flaps for reconstruction of soft tissue defects.
- Trial name
- NCT03658603
- Testing
- thoracodorsal artery perforator flap, latissimus dorsi flap
- Volunteers
- 40 people
- Sponsor
- Assiut University
Burn Scar Contraction
Perforator Based Interposition Plasty
Objective: to evaluate the perforator based interposition plasty in comparison to the standard technique (full thickness graft) for scar contracture releases. Study design: A randomised controlled multicentre intervention study.
- Trial name
- NCT01409759
- Testing
- Perforator based interposition flap
- Where
- 3 sites in Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Association of Dutch Burn Centres