Clinical trials: Performance Prediction
Acute Respiratory Distress Syndrome
Fluid Responsiveness Prediction During Prone Position
Predicting fluid responsiveness is primordial when caring for patients with circulatory shock as it allows correction of preload-dependent low cardiac output states, while preserving patients of the deleterious effects of…
- Trial name
- PROLOAD (NCT05898269)
- Testing
- Trendelenburg maneuver, End-expiratory occlusion test (EE OCC), End-expiratory and end-inspiratory occlusion test (EI OCC)
- Where
- 4 sites in France
- Volunteers
- 96 people
- Sponsor
- Hospices Civils de Lyon
Wounds and Injuries
Is There a Difference in the Mortality Prediction Performance of Two ICISS Approaches for Trauma Patients Admitted to Hospitals in Urban India?
This study aims to compare the predictive performance of two different approaches of the international classification of disease injury severity score (ICISS) using data from four public university hospitals in urban India.
- Trial name
- NCT02715739
- Testing
- No intervention
- Volunteers
- 3,921 people
- Sponsor
- Karolinska Institutet
Tracheobronchitis, Herpes Simplex Infection
Bronchoscopic Score for Prediction of Herpes Simplex-virus Type 1 (HSV-1) Reactivation
Tracheobronchial reactivation of HSV-1 is a common finding in critically ill patients and is associated with longer intensive care unit (ICU) stay and mechanical ventilation.
- Trial name
- NCT05331417
- Testing
- Patients with herpes-simplex infection requiring bronchoscopy
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Muenster
Cardiac Surgery, Rehabilitation
Physical Performance Testing and Frailty in Prediction of Early Postoperative Course After Cardiac Surgery
Standard risk prediction models in cardiac surgery (such as EuroSCORE II or STS score) are designed to analyze solely the risk of short-term postoperative mortality.
- Conditions
- Cardiac Surgery, Rehabilitation, Frailty, Physical Performance
- Trial name
- Cardiostep (NCT05166863)
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- Jan Gofus, MD, PhD
Burn Injury, In-Hospital Mortality
Burn Mortality Prediction Scores
This retrospective observational cohort study evaluates hospitalized burn admissions treated at the Burn Center of Gaziantep City Hospital between October 2023 and February 2026.
- Trial name
- BURN-PRED (NCT07689890)
- Testing
- Retrospective Prognostic Score Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 1,082 people
- Sponsor
- Gaziantep City Hospital
Bacteremia, Sepsis Bacterial
Prospective Validation of GRADY: A Machine Learning Model for Early Sepsis and Bacteremia Detection in ICU Patients
This study aims to prospectively validate the GRADY prediction models, which use machine learning algorithms to estimate the risk of gram-negative bacteremia and sepsis in intensive care unit (ICU) patients based on routinely…
- Trial name
- NCT07126106
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Mental Fatigue, Cognitive Performance
Predicting Declines in Attention and Memory During a Prolonged Mental Task
This study will investigate whether heart activity and changes in the skin's ability to conduct electricity can help predict performance during a demanding computer task.
- Trial name
- COG-PRED (NCT07877389)
- Testing
- Individually Calibrated Time Load Dual-back Task With Seated Rest
- Where
- Poland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- DSW Ideis University
Non Small Cell Lung Cancer
Veristrat as Predictor of Benefit of First Line Non Small Cell Lung Cancer (NSCLC) Patients From Standard Chemotherapy
VeriStrat® is a pretreatment blood-based test correlated with clinical outcome after EGFR-TKI therapy in non-small cell lung cancer (NSCLC) patients.
- Trial name
- NCT02055144
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
Performance Prediction
Cochlear-Implant-Performance-Prediction
Despite improved technology, many cochlear implant (CI) recipients still struggle to understand speech in noise (SIN). Because the bottom-up acoustic signal generated by the implant is distorted relative to normal-hearing…
- Trial name
- NCT07564388
- Testing
- cochlear implant user performance prediction
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Human Gastrointestinal Physiology Data
Modernization of in vivo-in Vitro Oral Bioperformance Prediction and Assessment
In vivo drug dissolution in the gastrointestinal (GI) tract is largely unmeasured. The purpose of this clinical study was to evaluate the in vivo drug dissolution and systemic absorption of the BCS Class IIa drug ibuprofen under…
- Trial name
- NCT02806869
- Testing
- Single dose of ibuprofen (800 mg tablet), Pulmocare, two 8.0 oz (236.6 mL) cans
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Colorectal Liver Metastasis (CRLM)
Multi-Reader Multi-Case Trial Evaluating Computer-Aided Tool for Prognostic Prediction of Colorectal Liver Metastases
This study evaluates the impact of a novel computer-aided prognostic prediction tool for colorectal liver metastases (CRLM) on clinician performance.
- Trial name
- NCT07027605
- Where
- China
- Volunteers
- 166 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Pancreatic Cancer
Prediction of Surgical Resectability After FOLFIRINOX Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Cancer: the Role of Diffusion Weighted Magnetic Resonance Imaging, Radiomics and Liquid Biopsy (PeRFormanCe Trial)
In this prospective study, new diagnostic tools will be explored for patients with borderline resectable and locally advanced pancreatic ductal adenocarcinoma (BR or LAPDA) who undergo neoadjuvant chemotherapy with FOLFIRINOX.
- Trial name
- PeRFormanCe (NCT05298722)
- Testing
- Imaging analysis of CT-scan and MRI with radiomics and genetic analysis of peripheral blood samples and questionnaires.
- Where
- 8 sites in Belgium, Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Quality of Life, Epilepsy (treatment Refractory)
Evaluation of the Epilepsy-related Quality of Life, Seizure-related Accidents and Validation of the Mjn-SERAS Solution in the Normalised Patient Environment with Real-World Data
The study will be prospective, multicentre, postmarketing clinical study, with a controlled and randomized design, to perform the analysis of 130 subjects with a clinical diagnosis of epilepsy, patients whose clinical semiology…
- Trial name
- SERAS_Home_RWD (NCT05845255)
- Testing
- mjn-SERAS
- Where
- 6 sites in Germany, Spain and 1 more
- Volunteers
- 130 people
- Sponsor
- MJN Neuroserveis, S.L
Acute Kidney Injury, Acute Renal Injury
Renal and Cardiac Risk Factors of AKI After Liver Transplantation
Background: Liver transplantation (LT) is an extensive operation with various factors contributing to the development of acute kidney injury in the perioperative period.
- Conditions
- Acute Kidney Injury, Acute Renal Injury, Liver Transplant; Complications
- Trial name
- NCT05666232
- Testing
- renal resistive index and myocardial performance index
- Volunteers
- 105 people
- Sponsor
- Mansoura University
Sleepiness
Effect of Countermeasures on Nocturnal Driving Performance
Sleep deprivation induces degradation of night-time driving ability via sleepiness. Because of conflicts between physiological needs and social or professional activities, it is necessary to develop affordable countermeasure to…
- Trial name
- KILLSLEEP (NCT01070004)
- Testing
- Real driving situation, Driving simulator
- Where
- 2 sites in France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Nitrogen Balance, Cancer
Per Kilogram Versus Nitrogen Balance Methods for Daily Protein Requirement in Cancer Patients
The goal of this study is to compare the effects of two dietary protein supplementation methods (per kg [PK] vs nitrogen balance equation [NBE]) on nutritional status, muscle strength, lean body mass, physical performance, and…
- Conditions
- Nitrogen Balance, Cancer, Protein Requirement
- Trial name
- NCT06824636
- Testing
- a personalized diet plan was prepared according to the calculated requirements of each patient by two expert dietitians
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Istanbul University
Aging, Aging Well
100-Year Human Aging Study
The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed clinical sites, mobile clinical sites, and an online participation pathway (current and future) to undergo…
- Conditions
- Aging, Aging Well, All-Cause Mortality, Mortality
- Trial name
- NCT07563777
- Testing
- Comprehensive Multi-System Clinical Screening
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
IVF
Pivotal Observational CHLOE Study
This pivotal study is an observational, prospective assessment, multi-center, databank based, clinical study aimed to evaluate the performance of CHLOE™ algorithm in prediction of blastocyst formation.
- Trial name
- NCT06111365
- Testing
- CHLOE
- Where
- 3 sites in United States
- Volunteers
- 59 people
- Sponsor
- Fairtility
Sepsis
Predicton of Sepsis Recovery Performance Subtypes Pilot Study
This study addresses critically ill sepsis patients' current literature reports of ongoing post-hospital discharge weakness and hospital readmissions.
- Trial name
- NCT05912413
- Testing
- there is no intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Fertility Disorders, Infertility
Performance Assessment of the MAGENTA Blast Algorithm for Embryo Prediction
This is a retrospective, observational, single-arm, multi-center study to evaluate the predictive performance of MAGENTA BLAST, an artificial intelligence (AI)-enabled software application, when used as analytical, adjunctive…
- Trial name
- NCT07464275
- Testing
- MAGENTA Blast
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- Future Fertility Inc.