Clinical trials: Performance of Colonoscopy
Patients With Potential Colorectal Neoplasia
Optimisation and Performance of Reduced Preparation CT Colography
To ascertain which of four combinations of low residue diet, reduced laxative dose and oral contrast agent is best tolerated by patients and optimally prepares the colon prior ro CT colonography
- Trial name
- NCT00212433
- Testing
- Tagitol V, Lo So, Readi-Cat 2
- Where
- 3 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- London North West Healthcare NHS Trust
Colorectal Cancer
Head to Head Study Epi proColon and FIT
The study aims to show non-inferiority in the clinical performance of the investigational assay, Epi proColon, to FIT using matched blood and stool specimens from screening-guideline eligible subjects.
- Trial name
- NCT01580540
- Where
- 70 sites in United States, Puerto Rico
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Epigenomics, Inc
Colonoscopy, Colorectal Neoplasms
Interest of Artificial Intelligence in Cancer Screening Colonoscopy
Artificial Intelligence (AI) to predict the histology of polyps per colonoscopy, offers a promising solution to reduce variation in colonoscopy performance.
- Conditions
- Colonoscopy, Colorectal Neoplasms, Intestinal Polyps, Deep Learning
- Trial name
- IA COLO (NCT04921488)
- Testing
- screening colonoscopy
- Where
- 5 sites in France
- Volunteers
- 194 people
- Sponsor
- University Hospital, Bordeaux
Colonic Disease
Performance of the Poseidon System for Fluid Management During Water-aided Colonoscopy
To validate the performance of the Poseidon System™ for fluid management during water-aided endoscopic procedures in the colon.
- Trial name
- NCT05512026
- Testing
- Feasibility Assessment
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- WAE Medical
Colonoscopy
Evaluation of the Use of Cap in Improving the Performance of Colonoscopy
The aim of this study is to compare the colonoscopy success rate, cecal time and polyp detection rate between cap-fitted colonoscopy and conventional colonoscopy.
- Trial name
- NCT00930462
- Testing
- Cap (Olympus Medical Systems: D-201-15004, D-201-14304 and D-201-12704)
- Where
- Australia
- Volunteers
- 400 people
- Sponsor
- Royal Prince Alfred Hospital, Sydney, Australia
Colon Cancer, Colon Polyp
Performance of Artificial Intelligence in Colonoscopy for Right Colon Polyp Detection
The aim of the study is to assess whether the use of artificial intelligence improves polyp detection in a segment of the colon (the right colon).
- Conditions
- Colon Cancer, Colon Polyp, Colon Lesion, Colon Adenocarcinoma
- Trial name
- AIRCOP (NCT06216405)
- Testing
- Colonoscopy
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Colonoscopy
A Clinical Investigation to Demonstrate the Performance of a New Enema (TF037) in Distal Bowel Cleansing Compared With Fleet Enema
This study is designed to assess the difference between the performance of a new enema (TF037) against Fleet enema in distal bowel cleansing.
- Trial name
- NCT01715272
- Testing
- TF037, Fleet enema
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Norgine
Desaturation of Blood
HFNC Versus Conventional Nasal Cannula in Oxygen Performance in Patients Receiving Colonoscopy Under IV Sedation
The purpose of this study is to investigate if high flow nasal cannula (HFNC), as compared to conventional nasal cannula, improves oxygenation and prevents desaturation events in obese patients undergoing colonoscopy.
- Trial name
- HFNC (NCT02968706)
- Testing
- High Flow Nasal Cannula, Conventional Nasal Cannula, Patient satisfaction questionnaire
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Aventura Hospital and Medical Center
Performance and Tolerance of Colonoscopy
Carolina-ColoWrap® in Colonoscopy Performance and Outcomes Study
Colonoscopy is the gold-standard for colorectal cancer screening in the US. However, complete colonoscopy can be a challenging technical procedure, even for expert gastroenterologists due to variations in patient anatomy…
- Trial name
- C3PO (NCT02025504)
- Testing
- ColoWrap
- Where
- 3 sites in United States
- Volunteers
- 350 people
- Sponsor
- ColoWrap, LLC
Sensitivity of the ADS in Identifying Polyps in Real-world Colonoscopy, Mean Number of Polyps Per Colonoscopy for Colonoscopists and Colonoscopists + ADS
Artificial Intelligence Identifying Polyps in Real-world Colonoscopy
Recently, artificial intelligence (AI) assisted image recognition has made remarkable breakthroughs in various medical fields with the developing of deep learning and conventional neural networks (CNNs).
- Trial name
- NCT03761771
- Testing
- colonoscopy withdrawal with the ADS monitoring
- Where
- 2 sites in China
- Volunteers
- 209 people
- Sponsor
- Zhaoshen Li
Colorectal Polyps
A Trial of an Audit and Feedback Report to Improve Colonoscopy Performance
This project aims to measure the impact of a physician report card (also called an audit \& feedback report) on colonoscopy performance.
- Trial name
- NCT02595775
- Testing
- Individualized A/F report, A/F report plus a high intensity intervention, A/F report plus a low intensity intervention
- Volunteers
- 833 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Colorectal Cancer, Adenomas
Colonoscopy Screening Using a Novel Slim Colonoscope - a Randomized Controlled Trial
The purpose of this study is to compare the performance of a new prototype colonoscope with a standard colonoscope used world-wide today.
- Trial name
- NCT01370928
- Testing
- Olympus PCF-Y0014-L, Standard colonoscope
- Where
- Norway
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Natural Killer Cell Cytokine Production
Measurement of NK Cell Activity in Whole Blood in Subjects Being Screened for Colorectal Cancer Using Colonoscopy
This study will look at measuring the activity of natural killer (NK) cells using the in vitro diagnostic device NK Vue in subjects being screened for colorectal cancer using colonoscopy.
- Trial name
- NCT02291198
- Testing
- NK Vue: NK cell activity in stimulated whole blood
- Where
- Canada
- Volunteers
- 1,081 people, healthy volunteers welcome
- Sponsor
- ATGen Canada Inc
Colonoscopy
Will Cap-Assisted Colonoscopy Improve Performance of Colonoscopy: A Randomized Clinical Trial
Observing the effects of an Olympus cap on the visibility and in adenoma detection during colonoscopy.
- Trial name
- CAC (NCT01126632)
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Colonic Irrigation
Evaluation of Performance and Safety of Colonic Irrigation With the Colon Hydromat as a Non-oral Bowel Preparation for Colonoscopy
This is a clinical study with a medical device that bears the CE mark (approval for marketing in the EU) and is applied within its intended use.
- Trial name
- NCT04684082
- Testing
- Colonic irrigation with the Colon Hydromat
- Where
- Germany
- Volunteers
- 28 people
- Sponsor
- Herrmann Apparatebau GmbH
Colonoscopy, Adenoma Detection Rate
Comparison of Adenoma Detection Rate in 3D vs. 2D Surveillance Colonoscopy
There is substantial evidence confirming that identifying and removing colorectal adenomas during colonoscopy helps prevent the development of colorectal cancer.
- Conditions
- Colonoscopy, Adenoma Detection Rate, Three Dimensional, Colon Polyps and Adenomas
- Trial name
- NCT07076966
- Testing
- 3D device
- Where
- 3 sites in Taiwan
- Volunteers
- 660 people
- Sponsor
- National Taiwan University Hospital
Adenoma Detection Rate, Colonoscopy
Comparison of the Performance Between Conventional Colonoscopy and 3D Colonoscopy in Positive Fecal Immunochemical Test Group
Background: Adenoma detection rate is one of the most quality indicator: an accumulating body of evidence has shown that detection and resection of pre-cancerous adenoma by colonoscopy could effectively prevent colorectal cancer…
- Conditions
- Adenoma Detection Rate, Colonoscopy, Three Dimensional, Fecal Immunochemical Test
- Trial name
- NCT06678477
- Testing
- 3D device
- Where
- 3 sites in Taiwan
- Volunteers
- 298 people
- Sponsor
- National Taiwan University Hospital
Polyp, Colorectal
Colorectal Polyp Clinical Decision Support Device Study
The study objective is to establish the efficacy of the colorectal polyp Clinical Decision Support Device (CDSD) in clinical use.
- Conditions
- Polyp, Colorectal, Colonoscopy
- Trial name
- CDSD (NCT04437615)
- Testing
- Colonoscopy, Clinical Decision Support Device
- Where
- United States
- Volunteers
- 2,379 people
- Sponsor
- Olympus Corporation of the Americas
Colorectal Cancer, Colonic Adenoma
Bowel Cleansing Performance of the Pure-Vu System in Patients With a History of Poor Bowel Preparation
The diagnostic accuracy and safety of colonoscopy highly depends on the quality of the pre-procedural bowel preparation. A past history of poor bowel preparation is the most important risk factor of inadequate bowel cleansing at…
- Conditions
- Colorectal Cancer, Colonic Adenoma, Bowel Preparation
- Trial name
- NCT04700410
- Testing
- Pure-Vu System
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 44 people
- Sponsor
- Radboud University Medical Center
Colorectal Polyp, Colorectal Adenoma
Evaluation of a CAM System for Colorectal Polyp Size Measurement
Accurate polyp size measurements are essential for risk stratification, selection of polypectomy techniques, and surveillance interval assignments.
- Trial name
- CAM (NCT06715384)
- Testing
- Polyp size measurement using autonomous AI measurement or AI-assisted human measurement with the CAM system
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Changhai Hospital