Clinical trials: Peri-Implant Mucositis
Periodontitis, Peri-implant Mucositis
Biological Responses Affecting Early-stage Dental Implant Placement in Patients With History of Periodontitis
This prospective parallel, double-blind, four-arm randomised controlled clinical study is planned to assess the difference in the level of the inflammatory biomarkers expressed following the placement of the first dental implant…
- Conditions
- Periodontitis, Peri-implant Mucositis, Peri-Implantitis
- Trial name
- NCT05834946
- Testing
- Megagen implant placement, Biomate-Swiss implant
- Where
- Malaysia
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Peri Implant Mucositis
Effect of Water Flossing on Gingival Inflammation Around Single Implants
This study aims to evaluate the effect of water floss in reversing peri- implant mucositis around dental implants
- Trial name
- NCT07364916
- Testing
- Water flosser, Tooth brush and string floss
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Peri-implant Mucositis
Ozonized In-office and Domiciliary Gels vs Chlorhexidine Gel 1% for the Management of Peri-implant Mucositis Sites
This is a split-mouth randomized controlled clinical trial (RCT). After signing the informed consent, patients satisfying the inclusion criteria will undergo supragingival and subgingival professional oral hygiene of both arches…
- Trial name
- NCT05256914
- Testing
- Ozoral Pro and Ozoral gel administration, Curasept chlorhexidine gel 1%
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Peri-implant Mucositis, Peri-Implantitis
Metabolomic and Proteomic Fingerprinting in Peri-implant Diseases
Due to the limited efficacy of its treatment modalities, there is a stringent need to improve the prevention and early diagnosis of peri-implantitis.
- Trial name
- NCT04283903
- Testing
- PICF
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Universidad Complutense de Madrid
Peri-implant Mucositis
Limosilactobacillus Reuteri as an Adjuvant in the Treatment of Peri-implant Mucositis
Mechanical debridement is the traditional method for the treatment of peri-implant mucositis and its success depends on the patient's correct oral hygiene.
- Trial name
- LRRCT (NCT05758103)
- Testing
- Limosilactobacillus reuteri Prodentis® (combining L. reuteri DSM 17938 and L. reuteri ATCC PTA 5289 strains)
- Where
- Portugal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Malo Clinic
Peri-Implantitis and Peri-implant Mucositis, Peri-implant Mucositis
Salivary Minerals in Patients With Peri-implantitis
Patients included in the study will be recruited after arriving at the Faculty of Dentistry of the University of Zagreb. During the clinical examination, the patient's periodontal status (bleeding during probing, and the depth of…
- Conditions
- Peri-Implantitis and Peri-implant Mucositis, Peri-implant Mucositis, Periimplant Bone Loss, Periimplant Diseases
- Trial name
- mineral-perio (NCT05897736)
- Volunteers
- 25 people
- Sponsor
- University of Zagreb
Peri-Implantitis and Peri-implant Mucositis
Peri-implant Vitamin D and Cathelicidin (LL-37) Levels
This research aims to explore the influence of vitamin D on the body's defense system by examining its impact on specific proteins involved in immune response and inflammation in the soft tissues surrounding dental implants.
- Trial name
- NCT06867250
- Testing
- The patients' periodontal clinical parameters were recorded. PISF samples were collected, and the evaluations of 25(OH)D and LL-37 were conducted using enzyme-linked immunosorbent assay.
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Altinbas University
Peri-Implantitis and Peri-implant Mucositis
SPiT-frequency II_Peri-implantitis
This is an interventional clinical study on the peri-implant treatment necessary to improve the clinical conditions surrounding dental implants registered with peri-implant inflammation.
- Trial name
- NCT06737315
- Testing
- Submocosal instrumentation using a ultrasonic device (PEEK). Submucosal cleaning
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University of Oslo
Peri-Implantitis, Peri-implant Mucositis
Proteomic Analysis of Newly Restored Single Implants
In 10 systemically healthy non-smokers, free of periodontitis, one newly restored implant (baseline-T0) and one corresponding tooth were followed over 12 months (T1). All implants were screw-retained, and platform-switched.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Periodontal Diseases
- Trial name
- NCT06379022
- Testing
- Plaque control
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Peri-implant Mucositis
Non Surgical Protocol for Treatment of Mucositis
Peri-implant mucositis is an important disease entity as a result of its high prevalence and the lack of a standard mode of therapy.
- Trial name
- NCT03951636
- Testing
- Mechanical debridement with curettes, Er:YAG laser, Air Powder
- Where
- Italy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Dental Implants, Cigarette Smoking
Triclosan Toothpaste as a Preventive Strategy of Mucositis in Smokers
The purpose of this trial was to determine the effect of a triclosan-containing toothpaste in the clinical parameters and in the profile of osteo-immunoinflammatory mediators in the peri-implant crevicular fluid (PICF) as a…
- Trial name
- NCT03241407
- Testing
- triclosan/copolymer/fluoride toothpaste
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Paulista University
Peri-implant Mucositis, Oral Bacterial Infection
Bacterial Microbiota Characterization on Implant-supported PEEK and Titanium Provisional Abutments
The aim of this study is to determine the relative abundances of the different bacterial phyla and families in the microbiota present on the surface of PEEK implant-supported provisional abutments compared to titanium…
- Conditions
- Peri-implant Mucositis, Oral Bacterial Infection, Bacterial Resistance
- Trial name
- NCT03998865
- Testing
- Provisional abutment material
- Where
- Chile
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Michael Wendler Ernst
PROMs, Peri-implantitis
Outcome After Dental Implant Treatment
The general aim of this project is to investigate the long-term treatment outcome after implant therapy. The patients' satisfaction with implant treatment will be studied and correlated to biological and technical problems.
- Conditions
- PROMs, Peri-implantitis, Mucositis, Periodontitis
- Trial name
- NCT02671812
- Volunteers
- 163 people
- Sponsor
- Folktandvården Stockholms län AB
Periodontal Disease Stage 2, Peri-Implantitis and Peri-implant Mucositis
Evaluation of Hydrogel Application in the Treatment of Periodontitis and Peri-implantitis
To date, systemic/local antibiotics, antimicrobials, laser application, and probiotics have been used as adjuncts to improve the outcome of non-surgical periodontal treatment for both periodontitis and peri-implantitis patients.
- Conditions
- Periodontal Disease Stage 2, Peri-Implantitis and Peri-implant Mucositis, Periodontal Regeneration
- Trial name
- NCT06740123
- Testing
- Nonsurgical periodontal treatment and application of H42® hydrogel to the peri-implant pocket, Nonsurgical periodontal treatment of periodontal pocket, Non-surgical periodontal treatment and application of H42® hydrogel to the periodontal pocket
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kutahya Health Sciences University
Peri-implant Mucositis
Effectiveness of Interproximal Cleaning Devices for Biofilm Removal Around Posterior Single Implants With Peri-Implant Mucositis
This randomized clinical trial aims to evaluate and compare the efficacy of different interproximal oral hygiene devices for biofilm removal around posterior single dental implants in patients diagnosed with peri-implant…
- Trial name
- NCT07393828
- Testing
- Participants assigned to this intervention group are instructed to perform daily interproximal plaque control around implant-supported crowns using the allocated interdental oral hygiene device (inter
- Volunteers
- 75 people
- Sponsor
- Universitat Internacional de Catalunya
Peri-implant Mucositis
Diode Laser Added to Non-Surgical Treatment for Peri-Implant Mucositis
This randomized controlled clinical trial evaluated the clinical and biological effects of adjunctive diode laser therapy in the non-surgical treatment of peri-implant mucositis.
- Trial name
- NCT07886593
- Testing
- Conventional Non-Surgical Treatment, Adjunctive Diode Laser Therapy
- Where
- Spain
- Volunteers
- 206 people
- Sponsor
- Universidad Europea de Valencia
Peri-implant Mucositis
Incidence of Peri-implant Mucositis in Patients With Treated Periodontitis
the objective of this study is to determine the incidence of peri-implant mucositis in patients with treated periodontitis and enrolled in periodontal maintenance and to evaluate the associated risk indicators.
- Trial name
- PiM_Inc (NCT05356806)
- Testing
- Supportive periodontal and periimplant care
- Where
- Spain
- Volunteers
- 277 people
- Sponsor
- Universidad Complutense de Madrid
Peri-Implantitis and Peri-implant Mucositis
Reconstructive Treatment of Peri-implantitis With Electrolytic Decontamination Versus Titanium Brushes
Implants diagnosed with peri-implantitis and amenable for bone reconstructive treatment will be enrolled in the study. The implants will randomly be treated with either an electrolytic or a mechanical cleaning of the implant…
- Trial name
- Galvo vs mech (NCT07814391)
- Testing
- test device GalvoSurge, Mechanical decontamination with titanium brush
- Volunteers
- 38 people
- Sponsor
- George Eastman Dental Hospital, Italy
Peri-implant Mucositis
Impacts of Oral Irrigation in Patients With Periimplant Mucositis
The present study aimed to investigate clinically the cleaning effectiveness of different treatment modalities, that is, oral irrigator or interdental brush usage addition to routine brushing and examine TGF-β1, IL-1β, t-PA, and…
- Trial name
- NCT03844035
- Testing
- Periimplant crevicular fluid (PICF) collection
- Volunteers
- 45 people
- Sponsor
- Ondokuz Mayıs University
Mucositis
Impact of Oral Hygiene Gels on Peri-implant Mucositis
Peri-implant mucositis is abnormal inflammation occurring around dental implants, increasing the risk of loss of bone support. The purpose of this study is to evaluate the impact of brushing the bacterial biofilm at the…
- Trial name
- NCT03243591
- Testing
- Livionex gel, Aquafresh gel
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Nebraska