Clinical trials: Peri-Implant Tissues
Dental Implant
Effect of Bone Graft Material ON Peri-Implant Phenotype .
This prospective three-arm controlled interventional clinical study evaluates the effects of NanoBone alone and NanoBone combined with platelet-rich fibrin (PRF) on peri-implant hard and soft tissue phenotype after dental implant…
- Trial name
- NCT07835451
- Testing
- Dental implant placement, NanoBone, NanoBone sticky bone plus CGF/PRF membrane
- Where
- Iraq
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Surface Roughness, Maintenance of Dental Implants
Comparison of the Effect of Teflon vs Non-Teflon Hand Scalers in the Maintenance of Peri-Implant Tissue
The buccal and lingual surface of the 23 participants' crowns will be randomly assigned to receive scaling and root planing with either Teflon scalers, or non-Teflon scalers after implant crown delivery.
- Conditions
- Surface Roughness, Maintenance of Dental Implants, Inflammation
- Trial name
- NCT03316937
- Testing
- Types of scalers
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Peri-implant Mucositis, Soft Tissue Inflammation
Effect of Free Gingival Grafting on Peri-implant Health
The goal of this randomized clinical study is to investigate the impact of soft tissue phenotype modification following free gingival grafting (FGG) in addition to the non-surgical mechanical therapy of peri-implant mucositis…
- Trial name
- NCT06392256
- Testing
- Non surgical therapy, Free gingival Grafting
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Gazi University
Peri-implantitis
Effect of Metallic Particles on the Progression of Peri-Implantitis
This observational cross-sectional study aims to investigate the presence and characteristics of metallic micro- and nanoparticles in peri-implant tissues and their potential association with peri-implantitis progression, the…
- Trial name
- NCT07792499
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Implant Complication
Vertical Soft Tissue Augmentation With CTG vs ADM
The study aims at comparing two different approaches for vertical soft tissue augmentation at implant sites exhibiting soft tissue dehiscences: autogenous connective tissue graft vs acellular dermal matrix + enamel matrix…
- Trial name
- NCT05729607
- Testing
- Vertical soft tissue augmentation
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Hopeless Tooth in Esthetic Zone, Loss of Soft and Hard Tissue Around Implant
Peri-implant Tissue Changes Using Dual Zone Concept With Connective Tissue Graft Versus Concentrated Growth Factor
Tooth extraction not only alters the bony architecture of the alveolar ridge, but it also has an impact on the surrounding soft tissues.
- Conditions
- Hopeless Tooth in Esthetic Zone, Loss of Soft and Hard Tissue Around Implant, Immediate Implant Placement
- Trial name
- NCT06728696
- Testing
- Immediate implant with with dual zone technique using concentrated growth factor graft., Immediate implant with dual zone technique using connective tissue graft.
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Peri-Implantitis, Peri-implant Mucositis
Lingual Keratinized Tissue in Fully Edentulous Patients and Its Impact on Implant Health
Cross-sectional study involving the measurement of the width of lingual keratinized tissue (in the implant locations) in fully edentulous patients restored with dental implants.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Recession, Gingival
- Trial name
- NCT06166017
- Testing
- Exposure to minimal amount of lingual keratinized tissue width
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- George Eastman Dental Hospital, Italy
Dental Implants, Single-Tooth
Differences Between Two Type Implants in Post-extraction Alveolus
One of the challenges of current implantology involves the preservation or reduction of existing bone resorption, mainly in the buccal bone plate, after tooth loss, which becomes of special importance in the anterior region of…
- Trial name
- NCT05665231
- Testing
- A - Bone defect (clinical variables), B- Bacterial plaque index (O'Leary index)(clinical variables), C- Probing depth
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Antibiotic
The Effect of Different Antibiotic Protocols on Peri-implant Tissue Health
The aim of the present project (non-inferiority trial) is to evaluate the effect of different antibiotic strategies (long-span vs.
- Trial name
- NCT06378502
- Testing
- Amoxicillin Short, Amoxicillin Long
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universita degli Studi di Genova
Peri-implant Tissue Response With Use of Customized Healing Abutments
Effect of Customized Healing Abutments on Peri-implant Soft Tissue and Bone
The goal of this clinical trial is to evaluate effect of customized healing abutment in patients who need single implant reconstruction.
- Trial name
- NCT06125418
- Testing
- customized healing abutment, standard healing abutment
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Patient Satisfaction
Influence of Digitalized Impression on Single Peri-implant Soft Tissue Profile
This randomized controlled clinical study will be carried out to compare the digital with conventional impression procedures for the restoration of single implants in an esthetic zone by assessing: 1.
- Trial name
- NCT06702969
- Testing
- Intra oral scanner, impression analog
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Peri-implantitis
Expression of Epithelial-Mesenchymal Transition Associated Markers in Peri-implant Tissues
Peri-implantitis is an inflammation of bacterial etiology characterized by inflammation of mucous membranes and bone loss around the dental implant.
- Trial name
- NCT05832541
- Where
- Iraq
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Dental Implant, Peri-Implantitis
Alveolar Ridge Sequelae Due to Peri-implantitis: a Retrospective Observational Study
The scientific evidence available at present regarding the alterations suffered by the alveolar ridge after the explantation of implants that have been considered to be abandoned due to periimplantitis, as well as the remaining…
- Conditions
- Dental Implant, Peri-Implantitis, Bone Remodeling
- Trial name
- NCT04534361
- Testing
- CBCT measurements
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Peri-Implant Health, Implant Complication
Influence of Zirconia Abutments on Peri-Implant Tissues in Single-Tooth Restorations
Objectives: To compare the influence of pre-fabricated titanium abutments and customized milled zirconia abutments on implant biocompatibility and the peri-implant region, as well as on radiographic bone loss and oral…
- Conditions
- Peri-Implant Health, Implant Complication, Prosthesis and Implants
- Trial name
- NCT07456163
- Testing
- Pre-fabricated standardized titanium abutments, Customized anatomical zirconia abutments
- Where
- Brazil
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Gingival Recession, Lack of Keratinized Attached Peri-implant Mucosa
Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination of Strip Gingival Graft and Acellular Dermal Matrix
This study is to compare the two techniques to achieve change in the tissue quality at areas of lack of Keratinized Tissue (KT) using soft tissue grafting with autogenous graft material (Free Gingival Graft)(FGG) vs Strip…
- Conditions
- Gingival Recession, Lack of Keratinized Attached Peri-implant Mucosa, Thin Gingiva
- Trial name
- NCT04920136
- Testing
- Strip Free gingival graft (SGG) + Acellular Dermal Matrix graft (ADM), Free Gingival graft
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Peri-Implantitis, Soft Tissue
Association of Keratinised Mucosa Around Implants and Teeth With Peri-implant/Periodontal Disease and Soft Tissue Conditioning
Lack of keratinised mucosa around dental implants and teeth is associated with plaque accumulation and worse tissue conditions. However, there is lack of data on the influence of the presence/lack of keratinised mucosa on the…
- Conditions
- Peri-Implantitis, Soft Tissue, Bone Gain
- Trial name
- NCT03501537
- Testing
- Free gingival graft obtained from the palate and debridement of the peri-implant lesion
- Where
- Spain
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Alveolar Bone Loss
Soft Tissue Width and Abutment Height Influence Peri-implant Bone Resorption
The purpose of this clinical and radiographic study will be to determine what influence on marginal bone loss has the thickness of soft tissues and the height of the prosthetic abutment and eventually determine which of the two…
- Trial name
- i-RES (NCT03229005)
- Testing
- implant insertion, operculectomy, prosthetic rehabilitation
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Maxillofacial Prosthesis Implantation, Extra-oral Implants
Implant Survival and Peri-abutment Tissue Reactions of Extra-oral Implants.
Patients with craniofacial defects caused by oncologic resection, traumatic events or congenital etiologies suffer from esthetic, functional and psychological problems.
- Conditions
- Maxillofacial Prosthesis Implantation, Extra-oral Implants, Extra-oral Prosthesis, Prostheses and Implants
- Trial name
- NCT03182361
- Testing
- Implantation of BioComp Industries cranio-maxillo-facial (CMF) screw implants
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Dental Implants
Peri-implant Soft Tissue Changes at Small Buccal Dehiscences
This study was designed to assess peri-implant soft tissue health, volume and marginal stability at implants sites which presented small buccal bone dehiscences (<3mm evaluated in a vertical direction) at the time of insertion.
- Trial name
- NCT07501715
- Testing
- Connective tissue graft, horizontal guided bone regeneration
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Peri-Implantitis
Soft Tissue Assessment in Screw-Retained Maxillary Complete Denture With Electric Welded Framework Versus Casted
comparing the changes in the soft tissue around the implants that will be joined by a metal framework either with electric welding or with the conventional casting method
- Trial name
- NCT04543864
- Testing
- Electric intraoral welding device, casting
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University