Clinical trials: Peri-Implant Tissues
Peri-implant Soft Tissue Healing
Spatiotemporal Single-cell Atlas of Peri-implant Soft Tissue Healing
This study aims to explore the dynamic changes in different cell types and their molecular regulatory mechanisms during the healing process of peri-implant soft tissues, using single-cell RNA sequencing (scRNA-seq) and spatial…
- Trial name
- NCT07279090
- Testing
- Healing Abutment Gingival Healing Post-Implantation
- Where
- China
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Stomatological Hospital Affiliated with Fujian Medical University
Peri-implant Mucosa Thickness, Peri-implant Mucosa Width
Soft Tissue Management in Peri-Implant Regions
Background:This study aimed to compare the effect of ribose cross-linked thick collagen membrane (RCCM) with that of subepithelial connective tissue graft (CTG) in sites with soft tissue deficiency in the horizontal aspect around…
- Conditions
- Peri-implant Mucosa Thickness, Peri-implant Mucosa Width, Peri-Implant Tissues
- Trial name
- NCT06880185
- Testing
- Connective Tissue Graft, Ribose Cross-Linked Thick Collagen Membrane
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ömer Alperen Kırmızıgül
Peri-Implant Tissues
The Effect of Injectable Platelet-Rich Fibrin in Peri-implant Soft Tissue
An inadequate amount of peri-implant soft tissue results in more plaque accumulation around the implants, peri-implant mucositis, marginal bone loss, mucosal recession, and/or attachment loss.
- Trial name
- NCT06753396
- Testing
- Platelet rich fibrin
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kutahya Health Sciences University
Peri-implant Bone Loss, Peri-Implant Tissues
Ten Year Follow up of Convergent Profile Implants
The aim of the study is to evaluate the marginal bone level (MBL) and pink aesthetic score (PES) changes on the short, medium and long-term, on a retrospective cohort of patients who received at least one "biotype implant" (DEI…
- Trial name
- NCT07089407
- Testing
- Dental implant placement
- Where
- Italy
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Osseointegration Failure of Dental Implant, Periimplantitis
Prospective Longitudinal Clinical Study for the Evaluation of Peri-implant Tissue and Osseointegration After Rehabilitation With Osseointegrated Implants
The success of rehabilitation with osseointegrated implants is associated with numerous factors, including patient characteristics, installed implants, proper planning, and the prosthetic connections used.
- Conditions
- Osseointegration Failure of Dental Implant, Periimplantitis, Peri-Implant Tissues, Peri-Implant Health
- Trial name
- Dental Implant (NCT06967649)
- Testing
- TITANIUM IMPLANT
- Where
- Brazil
- Volunteers
- 350 people
- Sponsor
- Universidade Federal Fluminense
Peri-implant Mucositis, Soft Tissue Inflammation
Effect of Free Gingival Grafting on Peri-implant Health
The goal of this randomized clinical study is to investigate the impact of soft tissue phenotype modification following free gingival grafting (FGG) in addition to the non-surgical mechanical therapy of peri-implant mucositis…
- Trial name
- NCT06392256
- Testing
- Non surgical therapy, Free gingival Grafting
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Gazi University
Peri-Implantitis, Peri-implant Mucositis
Histological, Genetic and Epigenetic Analysis of Procedures Related with Dental Implants
In this study genomic, proteomic and histological technologies for the search and characterization of epigenetic modifications and molecular or protein markers, useful in the diagnosis and progression of peri-implant diseases and…
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Implant Complication, Implant Tissue Failure
- Trial name
- NCT04421066
- Testing
- Gingival and bone sample collection, Healthy individuals
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Simón Pardiñas López
Peri-Implant Health, Peri-Implant Tissues
Comparison Between Free Gingival Graft and Palatal Pedicle Flap
Patients requiring KMW gain(mm) during uncovering surgery were included. Two surgical methods were compared: apically position flap with free gingival graft (FGG group) and the palatal pedicle flap with collagen matrix (PPF…
- Conditions
- Peri-Implant Health, Peri-Implant Tissues, Peri-implant Bone Level
- Trial name
- Pedicle (NCT06816680)
- Testing
- APF + FGG, PPF group
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Peri-implant Soft Tissue Healing
Comparison of BioHPP (High Performance Polymer) - vs Titanium- vs Zirconia Abutments
The project is a prospective, randomized, controlled study. The material BioHPP (High Performance Polymer) is compared with the gold-standard abutment materials titanium and zirconia in terms of peri-implant soft tissue healing.
- Trial name
- NCT06737263
- Testing
- BioHPP abutment, Titanium abutment, Zirconia abutment
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Graz
Peri-Implant Tissues
Evaluation of Peri-Implant Tissues of Different Implant Assisted Overdentures
The researchers will perform a parallel randomized, clinical trial involving completely edentulous healthy patients. Each participant will receive four dental implants in the anterior mandible.
- Trial name
- NCT06647199
- Testing
- the plaque index (PI), the bleeding index (BI), simplified gingival index(GI),
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Implant, Marginal Bone Loss
Manual or Digitally Guided Surgical Technique for Replacing Single Tooth Edentulism by Means of Sub-crestally Placed Implants. A 3-year Parallel Randomized Clinical Study on Marginal Bone Levels Stability
The aim of the present prospective study was to investigate after a 2-year of follow-up any influence of the surgical technique, manual or digitally guided, on peri-implant marginal bone levels stability in implants placed 1 mm…
- Conditions
- Dental Implant, Marginal Bone Loss, Peri Implant Health, Supral Tissue Height
- Trial name
- NCT06250621
- Testing
- Implant placement
- Where
- Italy
- Volunteers
- 18 people
- Sponsor
- ASST Santi Paolo e Carlo
Implant Tissue Failure, Dental Implant Failed
Laterally Rotated Flap for Soft Tissue Augmentation Around Maxillary Loaded Osseointegrated Dental Implant
Peri-implant mucositis is one of the most common peri-implant diseases. It was reported in more than 20% of the subjects rehabilitated with dental implants (Lee et al. 2017; Rodrigo et al. 2018; Wada et al. 2019).
- Conditions
- Implant Tissue Failure, Dental Implant Failed, Peri-Implantitis
- Trial name
- NCT06206499
- Testing
- soft tissue augmentation
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Peri-implant Tissue Response With Use of Customized Healing Abutments
Effect of Customized Healing Abutments on Peri-implant Soft Tissue and Bone
The goal of this clinical trial is to evaluate effect of customized healing abutment in patients who need single implant reconstruction.
- Trial name
- NCT06125418
- Testing
- customized healing abutment, standard healing abutment
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Peri-implant Bone Loss, Implant Stability
Comparison Between Two Different Tissue-Level Implant Systems: A Prospective Clinical Study
The objective of this prospective study is to compare clinically and radiographically two different tissue-level implants, in partially edentulous patients in the posterior area of the maxilla and mandible.
- Conditions
- Peri-implant Bone Loss, Implant Stability, Vertical Soft Tissue Thickness
- Trial name
- NCT04761445
- Testing
- Straumann Standard Plus implant and JDental care (JD) Octa implant
- Where
- Lebanon
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University