Clinical trials: Peri-Implant Tissues
Dental Implants,Peri-implantitis,Smoking
Effect of Heavy Smoking on Hard and Soft Tissue Parameters Prospective Clinical Trial
The Aim of this study randomized prospective clinical trial is to examine and compare periimplant tissue changes between heavy smokers and non-smokers at 12 months post loading using the alpha Bio Neo standard diameter implants…
- Trial name
- NCT03766022
- Testing
- Neo dental implant Alpha Bio Tec. Ltd.
- Where
- Israel
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Peri-implantitis
MicroRNAs and Cytokines in Peri-Implantitis Tissue
Peri-implantitis is a non-linear and accelerating pattern of loss of supporting bone tissue associated with clinical signs of inflammation and increased probing depths compared to baseline measurements.
- Trial name
- NCT05765942
- Where
- Iraq
- Volunteers
- 45 people
- Sponsor
- University of Baghdad
Oral Soft Tissue Conditions
A Comparative Clinical Study Between a Collagen Matrix and Collagen Membrane as Wound Protection During Ridge Preservation ARP
Patients in need of extraction of two teeth in combination with alveolar ridge preservation will be invited to participate in intra-subject RCT on ARP. Prior to surgery, a small-field low-dose CBCT is taken.
- Trial name
- ARP (NCT06029322)
- Testing
- Socket seal after alveolar ridge preservation
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Complete Edentulism
PeriImplant Soft Tissue and Marginal Bone Loss of Single Implant Mandibular Overdenture
There is a significant difference between CM LOC and ball attachment, when considering the peri-implant soft tissue health and marginal bone loss.
- Trial name
- NCT02881905
- Testing
- ball attachment, cm loc attachment
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Immediate Temporization and Soft Tissue Augmentation Around Delayed Implants
Comparison of Peri Implant Soft Tissue Esthetics With Immediate Temporization With and Without Subepithelial Connective Tissue Graft
The aim of this study is to clinically evaluate peri-implant soft tissue esthetics around single delayed implants in the esthetic zone.
- Trial name
- NCT03770975
- Testing
- delayed implant with immediate provisionaliztion and soft tissue graft, delayed implant placement with immediate provisionalization
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Missing Tooth
The Effect of Platform-Matching Versus Platform-Switching Dental Implants on Peri-implant Hard and Soft Tissue Healing
To compare platform-switched implants to platform-matched implants for replacement of a single missing tooth and their effect on: 1) Interproximal alveolar crest level in relation to implant platform. 2) Buccal implant recession.
- Trial name
- NCT02536716
- Testing
- Platform-matched dental implant, Platform-switched dental implant
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Peri-Implantitis, Peri-implant Mucositis
Lingual Keratinized Tissue in Fully Edentulous Patients and Its Impact on Implant Health
Cross-sectional study involving the measurement of the width of lingual keratinized tissue (in the implant locations) in fully edentulous patients restored with dental implants.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Recession, Gingival
- Trial name
- NCT06166017
- Testing
- Exposure to minimal amount of lingual keratinized tissue width
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- George Eastman Dental Hospital, Italy
Dental Implant
Peri-implant Soft Tissue Phenotype and Early Marginal Bone Loss After Dental Implant Placement
This prospective observational cohort study evaluated the relationship between peri-implant soft tissue characteristics and early marginal bone loss following dental implant placement.
- Trial name
- NCT07769125
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Karabuk University
Soft Tissue Augmentation Around Dental Implants
Evaluation of Buccal Pedicle Flap, Connective Tissue Graft and Acellular Dermal Matrix for Volumetric Augmentation of Peri-implant Mucosa
The aim of the study is to evaluate the efficacy of different soft tissue grafting techniques including buccal pedicle flap alone, free connective tissue graft and acellular dermal matrix for volumetric augmentation of…
- Trial name
- NCT06479733
- Testing
- buccal pedicle flap, connective tissue graft, acellular dermal matrix
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ghada Elhusseiny
Ultrasonography
Ultrasonography and Cone-Beam Computed Tomography for Peri-implant Tissue Evaluation
Objectives: Although cone-beam computed tomography (CBCT) is becoming a standard of care in implant therapy, concerns have been raised recently about its limitation in imaging peri-implant tissues due to artifacts.
- Trial name
- NCT04488302
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Michigan
Soft Tissue
Customized Impressions in Dental Implants - Soft Tissues Changes
Six patients with a single unit implant in the anterior maxilla (from premolar to premolar), after at least 3 months with provisional implant supported restoration will be submitted to definitive implant impressions.
- Trial name
- NCT03496428
- Testing
- Dental implant impressions- Different Techniques
- Where
- Portugal
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Implant, Healing
Different Customized Healing Abutment Materials on Peri-Implant Soft Tissue Profile
This study aimed to estimate the impact of various customized healing abutments materials on the peri-implant soft tissue profile
- Conditions
- Implant, Healing, Polyether Ether Ether Ketone, 3D Printed Hybrid Resin
- Trial name
- NCT07697066
- Testing
- Titanium healing abutment, Polyetheretherketone (PEEK), 3D-printed hybrid resin (P crownV4)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Peri-Implantitis, Peri-implant Mucositis
Proteomic Analysis of Newly Restored Single Implants
In 10 systemically healthy non-smokers, free of periodontitis, one newly restored implant (baseline-T0) and one corresponding tooth were followed over 12 months (T1). All implants were screw-retained, and platform-switched.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Periodontal Diseases
- Trial name
- NCT06379022
- Testing
- Plaque control
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Peri-implant Soft Tissue Healing
Soft Tissue Response and IL-1β Levels Around CAD/CAM-Milled vs 3D-Printed PMMA Healing Abutments
This study looked at how the gums and tissues around dental implants heal when using two different types of temporary healing caps made of PMMA (a common dental material).
- Trial name
- NCT07287722
- Testing
- CAD/CAM-Milled PMMA Healing Abutment, 3D-Printed PMMA Healing Abutment
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ali Hassan Eid Toto
Tooth Loss, Alveolar Bone Loss
Immediate Molar Implants With Customized Healing Abutments in Different Post-Extraction Socket Classes
Immediate implant placement into a fresh extraction socket shortens overall treatment time and reduces the number of surgical procedures, but the fit between the implant and the socket walls, and the resulting soft-tissue…
- Conditions
- Tooth Loss, Alveolar Bone Loss, Jaw, Edentulous, Partially
- Trial name
- IMPLA-CHA (NCT07801573)
- Testing
- Immediate implant placement with customized healing abutment
- Where
- Bulgaria
- Volunteers
- 60 people
- Sponsor
- Plovdiv Medical University
Peri-implant Bone and Soft Tissues
Dimensional Changes of Peri-implant Tissues Following Jumping Gap Grafting Using Erythropoietin Gel Mixed With Xenograft.
This study will be conducted to compare the effect of Erythropoietin gel mixed with xenograft versus xenograft alone in grafting the jumping gap around immediate implant.
- Trial name
- NCT07523412
- Testing
- Erythropoetin gel mixed with xenogenic bone graft, Xenogenic bone with gelling aget CMC ( carboxymethyl cellulose)
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Ain Shams University
Peri-implant Mucositis, Peri-Implantitis
Comparison of CTG and T-PRF on Peri-Implant Soft Tissue
The present study aimed to increase the thickness of the gingiva and prevent possible crestal bone resorption by placing the CTG or T-PRF membrane under the mucosa immediately after the implant treatment in individuals with thin…
- Conditions
- Peri-implant Mucositis, Peri-Implantitis, Thin Gingiva
- Trial name
- NCT04042194
- Testing
- Placement of Implants and Thickening Peri-Implant Mucosa with T-PRF, Placement of Implants and Thickening Peri-Implant Mucosa with CTG
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Keratinized Mucosa, Keratinized Tissue
Efficacy of Collagen Matrix for Peri-implant Soft Tissue Phenotype Modification
A stable band of keratinized mucosa (KM) around dental implants is thought to minimize tissue recession and provide resistance against mechanical, chemical, and microbial challenges, thereby preserving peri-implant tissue health.
- Trial name
- XCM versus FGG (NCT07056959)
- Testing
- Soft tissue substitute for peri-implant phenotype modification, Control Group - Free gingival graft for soft tissue augmentation
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Soft Tissue, Peri-Implant Health
Evaluation of Multilayered PRF in Comparison With Connective Tissue Graft by Sohn Poncho's Technique on Peri-implant Mucosal Enhancement in the Esthetic Zone
An effective biological seal is crucial for protecting and supporting dental implants, particularly in the anterior region for the desired esthetic outcome.PRF membrane and CTG has been utilized to improve peri-implant soft…
- Conditions
- Soft Tissue, Peri-Implant Health, Soft Tissue Augmentation at Dental Implants, Connective Tissue Graft
- Trial name
- NCT07649239
- Testing
- Platelet rich fibrin multilayered Platelet-rich fibrin (PRF) A t the second stage, Soft tissue augmentation around dental implants with CTG in the second stage
- Where
- United Arab Emirates
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Keratinized Mucosa
The Impact of Peri-implant Soft Tissue Properties on Patient-reported and Clinically Assessed Outcomes
The objective of this study is to evaluate patient discomfort while performing oral hygiene (OH) around implants with and without keratinized mucosa (KM) and assess peri-implant soft tissue esthetic satisfaction and other…
- Trial name
- NCT03396536
- Testing
- Evaluation of KM
- Volunteers
- 43 people
- Sponsor
- Tufts University