Clinical trials: Peri-Implantation Loss
Implant Clinical Survival, Restoration Survival
Retrospective Evaluation of Prosthetic Complications and Peri-implant Bone Resorption in Implant-supported Single Unit Fixed Restorations
This study evaluated the one-year outcomes of implant-supported single-tooth fixed restorations used to replace missing teeth. The aim was to assess the success rates of dental implants and identify potential complications during…
- Trial name
- NCT06709508
- Testing
- Examination group
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Özer İşisağ
Sensitivity, Peri-implant Mucositis
Sensitivity and Specificity of Peri-Implantitis-Related Parameters
Bleeding on probing demonstrated to have high specificity with certain level of sensitivity to detect periodontal disease. Again, understanding the weak hemidesmosome attachment to the implant surface is imperative to discern on…
- Conditions
- Sensitivity, Peri-implant Mucositis, Peri-Implantational Loss, Peri-Implantitis
- Trial name
- NCT03031392
- Testing
- Sensitivity test
- Where
- Spain
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Hearing Loss, Cochlear
Electrocochleography Function for Monitoring Residual Hearing
This trial is a pilot study to assess the feasibility of using Electrocochleography recorded from a cochlear implant intra-operatively in real time to monitor the progress of its insertion. Correlation between: 1.
- Trial name
- ECochG (NCT03848338)
- Testing
- Electrocochleography
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Completely Edentulous Maxilla, Implant Placement
Peri-Implant Marginal Bone Loss And Implant Stability In Maxillary Implant Overdenture When Using Osseodensification Versus Conventional Drills: A Randomized Clinical Trial
Is to compare between the conventional drills versus osseodensification drills for implant stability and peri-implant marginal bone loss in maxillary implant overdenture.
- Conditions
- Completely Edentulous Maxilla, Implant Placement, Maxillary Implant Overdenture
- Trial name
- NCT05559632
- Testing
- osteotomy for implant placement
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Implant Failed
Digital Assessment at Peri-implant Tissues After Immediate Implants With Customized Healing Abutments and Connective Tissue Grafts
After a single-tooth extraction, physiological remodeling processes are unavoidable which leads to a total loss of the periodontal ligament and resorption of the bundle bone.
- Trial name
- NCT05060055
- Testing
- Immediate dental implant placement
- Where
- Portugal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidade Católica Portuguesa
Tooth Loss in the Anterior Maxilla, Alveolar Bone Loss* / Therapy
Beta-Tricalcium Phosphate Grafting of Peri-implant Jumping Gaps Greater Than 2 mm in Immediate Implants
This randomized controlled trial evaluated whether grafting the peri-implant "jumping gap" with injectable β-tricalcium phosphate (β-TCP) improves outcomes after immediate implant placement in sites where the horizontal gap…
- Trial name
- NCT07709676
- Testing
- Experimental: Test: beta-tricalcium phosphate grafting
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Minia University
Tooth Loss, Peri-implant Mucosa Defect
Comparison of Two Different Surgical Approaches To Increase Peri-Implant Mucosa Thickness
The purpose of this non-inferiority trial is to determine the clinical efficacy of acellular dermal matrix (ADM) in the augmentation of the gum around dental implants as compared to an autologous gum graft (sCTG) obtained from…
- Trial name
- NCT02450383
- Testing
- Acellular Dermal Matrix, Autologous subepithelial connective tissue graft
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Jaw, Edentulous, Edentulism, Complete
Tri-Lobe vs. Hexagonal Connections in Immediately Loaded Mandibular Overdentures
Objective: Compare changes in crestal bone height and peri-implant bone density using cone-beam computed tomography (CBCT) at baseline, 6 months, and 12 months post-placement.
- Conditions
- Jaw, Edentulous, Edentulism, Complete, Peri-implant Bone Loss
- Trial name
- NCT07824219
- Testing
- ReActive Implant System (Internal Tri-Lobe Platform), Legacy II Implant System (Internal Hexagonal Platform)
- Where
- United Arab Emirates
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Peri-implantitis, Alveolar Bone Loss
Diagnostic Accuracy of Large Language Models for Peri-Implant Marginal Bone Loss on Panoramic Radiographs
Dental implants are a routine treatment for missing teeth, but the number of implants affected by peri-implantitis, a progressive inflammatory disease of the tissues around implants, is increasing.
- Conditions
- Peri-implantitis, Alveolar Bone Loss, Dental Implant
- Trial name
- NCT07907900
- Testing
- Multimodal large language model evaluation (ChatGPT, Gemini, Claude, DeepSeek, Grok)
- Where
- Turkey (Türkiye)
- Volunteers
- 784 people, healthy volunteers welcome
- Sponsor
- Ankara University
Dental Implant, Marginal Bone Loss
Effect of Cover Screws and Healing Abutments on Marginal Bone Loss
This randomized clinical trial aims to compare the effects of using a cover screw or a healing abutment during dental implant placement on short-term marginal bone loss.
- Trial name
- NCT07815977
- Testing
- Cover Screw, Healing Abutment
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Peri-implant Bone Loss, Implant Stability
Comparison Between Two Different Tissue-Level Implant Systems: A Prospective Clinical Study
The objective of this prospective study is to compare clinically and radiographically two different tissue-level implants, in partially edentulous patients in the posterior area of the maxilla and mandible.
- Conditions
- Peri-implant Bone Loss, Implant Stability, Vertical Soft Tissue Thickness
- Trial name
- NCT04761445
- Testing
- Straumann Standard Plus implant and JDental care (JD) Octa implant
- Where
- Lebanon
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Bone Loss
Radiographic Evaluation of All-on-4 Implant Prosthesis With Different Materials and Bar Construction Techniques
Eighteen patients will be selected from the outpatient clinic of the Prosthodontic Department, Faculty of Dentistry, Mansoura University seeking prosthetic rehabilitation.
- Trial name
- NCT06071689
- Testing
- screw retained prosthesis
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Implant, Platelet Rich Fibrin
The Effect of Platelet Rich Fibrin Layers on Peri-implant Tissue Phenotype
The present investigation seeks to determine how varying quantities of Platelet-Rich Fibrin (PRF) membranes influence the repair of both gingival and osseous tissues adjacent to dental implants.
- Conditions
- Dental Implant, Platelet Rich Fibrin, Keratinized Mucosa, Crestal Bone Loss
- Trial name
- NCT07033351
- Testing
- Dental implant placement without PRF, Single-layer PRF membrane application, Triple-layer PRF membrane application
- Where
- Iraq
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Bone Loss, Inflammation
Healing of Bone/Soft Tissue to Different Abutment Biomaterials and the Impact on Marginal Bone Loss
In patients that require a dental implant, does zirconia compared to titanium, or cad-cam acrylic abutments, provide less inflammation, marginal bone loss or infection during the osseointegration period ?
- Trial name
- NCT01961635
- Testing
- dental implants, Zirconia abutments, Titanium Abutments
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Tooth Loss, Edentulous Jaw
Molecular Content of Peri-implant Sulcus During Wound Healing and Osseointegration Following Drilling and Piezosurgery
This study aims to evaluate the levels of cytokines, chemokines and growth factors in peri-implant sulcular fluid (PISF) during healing and osseointegration at osteotomy sites prepared either with piezosurgery (PS) or drills (D).
- Trial name
- NCT03538184
- Testing
- Piezosurgery, Drill
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ege University
Peri-Implantitis, Implant Complication
"Surgical Vs. Non-surgical Peri-implant Therapy"
The aim of this randomized clinical trial is to evaluate the effectiveness, in terms of clinical and radiographic changes, of non-surgical peri-implant therapy (mechanical/chemical) versus regenerative surgical therapy (xenograft…
- Conditions
- Peri-Implantitis, Implant Complication, Bone Loss
- Trial name
- NCT05168891
- Testing
- Surgical therapy, Non-surgical therapy of peri-implantitis
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Periodontal Bone Loss
Evaluation of Peri Implant Bone Loss of Immediately Versus Conventionally Loaded Implants With a Single Prosthesis
The main objective of this prospective, controlled, and randomized clinical study is to evaluate the peri-implant bone loss of immediately loaded versus conventionally loaded implants with a single prosthesis.
- Trial name
- Mpigozzo (NCT02416700)
- Testing
- immediate implant surgery, implant surgery (Straumann®)
- Where
- Brazil
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Mônica Nogueira Pigozzo
Dental Implant-Abutment Designs, Marginal Bone Loss in Different Abutment Designs
Peri-implant Tissues Changes for Different Abutment Shapes and Heights
The goal of this randomized clinical trial is to investigate the influence of supracrestal soft tissue on abutments of different heights (2-mm vs. 3-mm) and shapes (cylindrical abutment vs.
- Conditions
- Dental Implant-Abutment Designs, Marginal Bone Loss in Different Abutment Designs, Soft Tissue Management in Subcrestal Dental Implants
- Trial name
- NCT07509281
- Testing
- Bone-Level Implant Placement with Transmucosal Abutment and One Abutment-One Time Protocol
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Edentulous Jaw, Bone Loss, Alveolar
Effects of Different Centrifuged Platelet Concentrates on Bone Remodelling Around Dental Implants
Platelet concentrates obtained from blood have been used as regenerative biomaterials in periodontal surgery. Along with the migration and proliferation of osteogenic cells, platelets accelerate bone regeneration by increasing…
- Conditions
- Edentulous Jaw, Bone Loss, Alveolar, Resorption, Bone
- Trial name
- NCT04851002
- Testing
- Application of concentrated growth factor with dental implants, Application of advanced platelet rich fibrin with dental implants, Control side of concentrated growth factor study group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Muhammet Atilgan
Peri-Implantitis, Peri-implant Mucositis
Association Between Smoking Habit and Peri-implant Diseases: a Case Control Study
Although smoking has been proposed as well, as a risk factor/indicator for peri-implantitis, there is currently no conclusive evidence. The current literature confronts the inconclusive evidence of tobacco for a risk factor.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Bone Loss, Alveolar
- Trial name
- NCT04952428
- Testing
- Re-examination visit ("today visit")
- Where
- Spain
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya