Clinical trials: Peri-Implantitis
Peri Implantitis
a Randomized Clinical Trial Evaluating Plaque Removal Around Dental Implants
This aim of this study is to compare different oral hygiene aids for the ability to remove plaque in patients who went through dental implant treatment and are currently on a maintenance program at the Graduate Periodontal…
- Trial name
- NCT02091609
- Testing
- dental interproximal brush, dental floss
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Peri-implant Mucositis, Peri-Implantitis
Distance Between Dental Implants as a Risk Indicator for Peri-implant Disease.
The aim of this study is to analyse contiguous dental implants and its peri-implant status depending on different inter-implant distances.
- Trial name
- NCT06364982
- Testing
- Two contiguous dental implants placed with less ≤ 3mm from each other., Two contiguous dental implants placed with > 3mm from each other.
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Peri-implantitis
Expression of Epithelial-Mesenchymal Transition Associated Markers in Peri-implant Tissues
Peri-implantitis is an inflammation of bacterial etiology characterized by inflammation of mucous membranes and bone loss around the dental implant.
- Trial name
- NCT05832541
- Where
- Iraq
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Implant Complication, Peri-Implantitis
Treatment of Peri-implant Bone Dehiscence Using Autogenous Tooth Plate
The current trial aim was to evaluate clinically and radiographically the changes around dental implants inserted immediately in maxillary anterior esthetic zone using a novel combination of autogenous demineralized tooth graft.
- Conditions
- Implant Complication, Peri-Implantitis, Periodontal Diseases
- Trial name
- NCT06313216
- Testing
- duoteck membrane, autogenous demineralized tooth graft, autogenous demineralized tooth graft and plate
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Periimplantitis
Evaluatıon of TREM-1, MMP-8 and TIMP-1 Levels in Perı-Implant Crevicular Fluıd of Perı-Implanted Indıvıduals
The aim of this study was to evaluate the relationship between Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1), Matrix Metalloproteinases-8 (MMP-8) and Tissue Inhibitors of Metalloproteinases-1 (TIMP-1) levels in…
- Trial name
- NCT07379892
- Testing
- Collection of PICF samples
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Peri-Implant Mucositis, Peri-implantitis
Impact of an AI-Based Chatbot on Implant Patient Management: RCT
Background: Dental implant therapy is a well-established and predictable procedure for replacing missing teeth, with high long-term survival rates.
- Conditions
- Peri-Implant Mucositis, Peri-implantitis, Peri-Implant Health, Peri-implant Inflammation
- Trial name
- NCT07300657
- Testing
- AI Chatbot, Standard Oral Hygiene Education
- Where
- Italy
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Catania
Periodontitis, Periimplantitis
PPAR, RXR, and VDR Expressions in Peri-implantitis
ABSTRACT Objective: Periodontitis and peri-implantitis are the irreversible destructive diseases of the periodontal and peri-implant tissues.
- Trial name
- NCT04020146
- Testing
- Gingival biopsies
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Peri-Implantitis, Peri-implant Mucositis
Characterizing the Inflammation Around Dental Implants
The use of titanium dental implants has become a common modern treatment to restore teeth. Although the success rate of dental implants is high, inflammation around the dental implant still occurs.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Implant Site Reaction, Implant Site Infection
- Trial name
- NCT05675241
- Testing
- Clinical examination of a dental implant, Radiological Examination, Peri-implant crevicular fluid sample collection
- Where
- Canada
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- McGill University
Peri-Implantitis, Periodontal Diseases
COMPARISION OF DIFFERENT TREATMENT METHODS OF PERI-IMPLANTITIS
In this randomized, controlled study, 18 patients with peri-implantitis were included. A total of forty dental implants were debrided with either ultrasonic instruments (test, n=20) or plastic scaler (control, n=20).
- Trial name
- NCT03241953
- Testing
- Periodontal surgery
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Peri-implant Mucositis, Peri-Implantitis
Experimental Peri-implant Mucositis on Implant Sites That Were Previously Treated With or Without Implantoplasty
This controlled clinical trial will assess clinically, immunologically, and microbiologically the healing of experimental peri-implant mucositis (PIM) lesions in implants treated previously with implantoplasty (IP) compared to…
- Trial name
- NCT06063876
- Testing
- Induction of experimental peri-implant mucositis, Resolution of experimental peri-implant mucositis
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Peri-implantitis
Surgical Protocol for Peri-implantitis Treatment
Peri-implant diseases are common post-restorative complications in implant rehabilitations and they occur with an incidence of 12-43%.
- Trial name
- NCT03801187
- Testing
- chlorhexidine, Er:YAG laser, Air-Powder
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Peri-Implantitis
HIF-1 Alpha, VEGF and MMP-8 Levels in PICF of Smokers Versus Non Smokers
Smoking is a major risk factor for developing peri-implantitis so the current study is comparing inflammatory markers in smokers versus non smokers to know if they have a potential role in pathogenesis of peri-implantitis
- Trial name
- NCT05325918
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Peri-Implantitis
Understanding, Modulation and Memorization of Indicators Associated to Peri-implantitis
Communication strategies are encouraged to enhance patients´ understanding of potential events related to implant therapy such as peri-implantitis.
- Trial name
- NCT04543604
- Testing
- Leatlet + visual aid (pictogram), Leaflet + no visual aid (no pictogram)
- Where
- Spain
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Peri-Implantitis, Dental Implant Failed
Assessment of Efficacy of Calprotectin and Cross-linked N-telopeptides
The study aims to assess the efficacy of Calprotectin and cross-linked N-telopeptides of type I collagen levels in crevicular fluid as a biomarker in patients with peri-implantitis.
- Trial name
- NCT04177732
- Testing
- Collection of sulcular (crevicular) fluid, Probing depth, Bleeding on probing
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mansour Assery
Dental Implant Failed, Peri-Implantitis
Comparison of Dental Implants with Different Surface Properties
This controlled, parallel clinical study aims to compare the effect of fixed prosthetic restorations placed in the posterior region with different implant surfaces on clinical and peri-implant marginal bone loss.
- Trial name
- NCT06508723
- Testing
- Dental implant placement
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Dental Plaque, Oral Biofilm
Investigation of Biofilm Formation on Temporary push-on Rings of Implant Crowns
This in-vivo study investigates early (48h), mature (2 weeks) and long-term (3 months) biofilm formation and composition on temporary push-on cones (exchangeable conical rings) made of noble-alloy-based materials (Pagalinor, PA)…
- Conditions
- Dental Plaque, Oral Biofilm, Peri-implantitis
- Trial name
- NCT05122897
- Testing
- Rings made of PA (test), Rings made of TAN (control)
- Where
- Switzerland
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Implant Tissue Failure, Dental Implant Failed
Laterally Rotated Flap for Soft Tissue Augmentation Around Maxillary Loaded Osseointegrated Dental Implant
Peri-implant mucositis is one of the most common peri-implant diseases. It was reported in more than 20% of the subjects rehabilitated with dental implants (Lee et al. 2017; Rodrigo et al. 2018; Wada et al. 2019).
- Conditions
- Implant Tissue Failure, Dental Implant Failed, Peri-Implantitis
- Trial name
- NCT06206499
- Testing
- soft tissue augmentation
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Peri-Implantitis
Metronidazole as an Adjunct of Non- Surgical Treatment of Peri-implantitis
The use of systemic antibiotics as and adjunct to non-surgical peri-implant therapy may be an improvement in comparison to these therapies alone.
- Trial name
- NCT03564301
- Testing
- Metronidazole 250 MG
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Juan Blanco Carrión
Dental Implant Failed, Peri-implant Mucositis
Erythritol vs Ultrasonic Scaler Prophylaxis Systems on Dental Implants With Crowns Made by Different Materials
The aim of the study is to assess which prophylaxis methods is the most suitable for peri-implant hygiene between erythritol and ultrasonic scaler with peek inserts. A randomized clinical trial will be conducted on the patient.
- Conditions
- Dental Implant Failed, Peri-implant Mucositis, Peri-Implantitis
- Trial name
- NCT06288919
- Testing
- Erythritol prophylactic powders, Ultrasonic scaler with peek inserts
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Peri-Implantitis, Alveolar Bone Loss
Non-Surgical Treatment of Peri-Implantitis With Ultrasonic Carbon Tip
As the frequency of dental implants increases, the incidence of complications and peri-implant diseases also increases. Early diagnosis and treatment of the disease is important to prevent consequences up to implant loss.
- Trial name
- NCT06514677
- Testing
- Ultrasonic Carbon Tip, Titanium Curette
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University