Clinical trials: Peri-implant Soft Tissue Augmentation
Peri-Implantational Loss, Surgical Wound
Strip Graft w/ Xenogeneic Matrix vs Free Gingival Graft for the Augmentation of Peri-implant Keratinized Mucosa
The primary objective of this study is to compare changes in peri-implant keratinized mucosa (PIKM) following the application of apically repositioned flap (ARF) using a combination of a Strip graft and a Xenogeneic matrix, or…
- Conditions
- Peri-Implantational Loss, Surgical Wound, Healing Surgical Wounds, Thin-gingiva
- Trial name
- NCT06261268
- Testing
- Strip graft with Mucograft, Free gingival graft
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Peri-implantitis, Soft Tissue Augmentation at Dental Implants
Adjunctive Keratinized Mucosa Augmentation in Peri-Implantitis
This study aims to increase the width and thickness of peri-implant keratinized mucosa (KM) by transferring a properly dimensioned free gingival graft (FGG) from the palatal donor site and to evaluate its effect as an adjunctive…
- Trial name
- NCT07471386
- Testing
- Submucosal debridman + saline irrigation, Free gingival graft surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Mucositis
Surgical Protocol for Prevention of Mucositis
The main goal of implant therapy is to obtain long-term peri-implant health. Among local risk factors in the etiology of peri-implant diseases the absence of keratinized tissue (KT) around the implant has been reported.
- Trial name
- NCT04628520
- Testing
- Free gingival graft, Collagen matrix, Maintenance
- Where
- Italy
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Soft Tissue Augmentation
Soft Tissue Evaluation Around Implants Using Prf or a Palatal Pedicle
Clinical Evaluation of Peri-Implant Soft Tissue Around Immediately Placed Implants Using PRF Membrane Versus The Palatal Pedicle Soft Tissue Graft: A Randomized Controlled Clinical Trial.
- Trial name
- NCT03224442
- Testing
- PRF, Palatal Pedicle
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Missing Teeth
Enhancing Soft Tissues Around Inserted Implants by Two Different Methods
This randomized controlled clinical trial investigates the efficacy of xenogeneic collagen matrix (XCM) versus autogenous subepithelial connective tissue graft (SCTG) in enhancing the peri-implant soft tissue profile around…
- Trial name
- NCT06837688
- Testing
- Peri-implant soft tissue augmentation using connective tissue graft, Peri-implant soft tissue augmentation using xenogenic collagen matrix
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Damascus University
Keratinized Mucosa Deficiency, Peri-implant Soft Tissue
Apical Flap Repositioning vs. Mucosa Excision With Free Gingival Grafts for Peri-Implant Keratinized Mucosa Augmentation
The goal of this clinical trial is to learn which surgical technique works better to increase the amount of firm gum tissue (called keratinized mucosa) around dental implants in adults.
- Conditions
- Keratinized Mucosa Deficiency, Peri-implant Soft Tissue, Dental Implants
- Trial name
- FGGIF (NCT07772414)
- Testing
- Free gingival graft with apical flap repositioning, Free gingival graft with vestibular mucosa excision
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Barcelona
Peri-Implant Health, Peri-Implant Tissues
Comparison Between Free Gingival Graft and Palatal Pedicle Flap
Patients requiring KMW gain(mm) during uncovering surgery were included. Two surgical methods were compared: apically position flap with free gingival graft (FGG group) and the palatal pedicle flap with collagen matrix (PPF…
- Conditions
- Peri-Implant Health, Peri-Implant Tissues, Peri-implant Bone Level
- Trial name
- Pedicle (NCT06816680)
- Testing
- APF + FGG, PPF group
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Keratinized Mucosa, Keratinized Tissue
Efficacy of Collagen Matrix for Peri-implant Soft Tissue Phenotype Modification
A stable band of keratinized mucosa (KM) around dental implants is thought to minimize tissue recession and provide resistance against mechanical, chemical, and microbial challenges, thereby preserving peri-implant tissue health.
- Trial name
- XCM versus FGG (NCT07056959)
- Testing
- Soft tissue substitute for peri-implant phenotype modification, Control Group - Free gingival graft for soft tissue augmentation
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Immediate Temporization and Soft Tissue Augmentation Around Delayed Implants
Comparison of Peri Implant Soft Tissue Esthetics With Immediate Temporization With and Without Subepithelial Connective Tissue Graft
The aim of this study is to clinically evaluate peri-implant soft tissue esthetics around single delayed implants in the esthetic zone.
- Trial name
- NCT03770975
- Testing
- delayed implant with immediate provisionaliztion and soft tissue graft, delayed implant placement with immediate provisionalization
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Atrophy of Gingiva
Volumetric Evaluation of Gingival Augmentation Around Dental Implants
The goal of this observational prospective study is to objectively assess the dimensional (volume \& linear variance) and clinical changes of vestibular gingival soft tissues upon treatment with laser-aided pouch roll…
- Trial name
- NCT06057363
- Testing
- volumetric evaluation of gingival augmentation around dental implants
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Odontostomatologic Laser Therapy Center, Florence, Italy
Implant Complication
Vertical Soft Tissue Augmentation With CTG vs ADM
The study aims at comparing two different approaches for vertical soft tissue augmentation at implant sites exhibiting soft tissue dehiscences: autogenous connective tissue graft vs acellular dermal matrix + enamel matrix…
- Trial name
- NCT05729607
- Testing
- Vertical soft tissue augmentation
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Immediate Dental Implant Placement, Dental Implant
Influence of Acellular Dermal Matrix on Peri-implant Soft Tissue Phenotype and Marginal Bone Loss
To evaluate soft tissue augmentation using acellular dermal matrix (ADM) over immediately placed dental implants in anterior maxilla.
- Conditions
- Immediate Dental Implant Placement, Dental Implant, Acellular Dermal Matrix, Polytetrafluoroethylene
- Trial name
- ADM (NCT07573020)
- Testing
- Polytetrafluoroethylene coverage, Acellular Dermal Matrix
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Mansoura University
Soft Tissue, Peri-Implant Health
Evaluation of Multilayered PRF in Comparison With Connective Tissue Graft by Sohn Poncho's Technique on Peri-implant Mucosal Enhancement in the Esthetic Zone
An effective biological seal is crucial for protecting and supporting dental implants, particularly in the anterior region for the desired esthetic outcome.PRF membrane and CTG has been utilized to improve peri-implant soft…
- Conditions
- Soft Tissue, Peri-Implant Health, Soft Tissue Augmentation at Dental Implants, Connective Tissue Graft
- Trial name
- NCT07649239
- Testing
- Platelet rich fibrin multilayered Platelet-rich fibrin (PRF) A t the second stage, Soft tissue augmentation around dental implants with CTG in the second stage
- Where
- United Arab Emirates
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Dental Implants, Ceramic Implant
Zirconia Implants: Practice-based Evidence
This study is a prospective case series clinical study to examine the effectiveness of Ceramic dental implants manufactured by Swiss Dental Solutions (SDS).
- Trial name
- SDS (NCT06314425)
- Testing
- Immediate dental implants placements on fresh sockets after tooth extraction
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Swiss Dental Solutions
Peri-implant Soft Tissue Deficiency, Partial Edentulism
Soft Tissue Augmentation Around Dental Implants Using Connective Tissue Graft, Submerged Tenting Abutment, or Sub-crestal Implant Placement
Peri-implant soft tissue thickness is an important determinant of the long-term stability and success of dental implants. Patients with a thin peri-implant soft tissue phenotype are at increased risk of soft tissue recession…
- Conditions
- Peri-implant Soft Tissue Deficiency, Partial Edentulism, Tooth Loss
- Trial name
- NCT07714265
- Testing
- subepithelial connective tissue graft, Submerged Tenting Abutment, Sub-crestal Implant Placement
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Misr International University
Thin Peri-implant Mucosal Phenotype
Peri-implant Soft Tissue Augmentation Using Microneedling With i-PRF vs. Connective Tissue Graft
This randomized controlled clinical trial aims to evaluate a minimally invasive technique for peri-implant soft tissue augmentation using microneedling combined with injectable platelet-rich fibrin (i-PRF) compared with the…
- Trial name
- NCT07667855
- Testing
- Connective Tissue Graft (CTG), Microneedling with Injectable Platelet-Rich Fibrin (MN+i-PRF)
- Where
- Lebanon
- Volunteers
- 24 people
- Sponsor
- Beirut Arab University
Peri-implant Bone and Soft Tissues
Sandwich vs. Mixed Bone Augmentation for Implant Placement
This study is being done to see which of two common grafting techniques-mixing two different grafting materials or layering two grafting materials-works better to augment bone volume next to participant's dental implant(s).
- Trial name
- NCT07832565
- Testing
- Sandwich bone augmentation, Mixed bone augmentation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Implant Tissue Failure, Dental Implant Failed
Laterally Rotated Flap for Soft Tissue Augmentation Around Maxillary Loaded Osseointegrated Dental Implant
Peri-implant mucositis is one of the most common peri-implant diseases. It was reported in more than 20% of the subjects rehabilitated with dental implants (Lee et al. 2017; Rodrigo et al. 2018; Wada et al. 2019).
- Conditions
- Implant Tissue Failure, Dental Implant Failed, Peri-Implantitis
- Trial name
- NCT06206499
- Testing
- soft tissue augmentation
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Soft Tissue Atrophy
Peri-Implant Soft Tissue Augmentation Using a Free Connective Tissue Graft With an Epithelial Collar
A prospective randomized interventional clinical trial (RCT) with a parallel-group design is planned. The study sample will include 32 patients randomly allocated into two groups according to the surgical intervention performed.
- Trial name
- NCT07626866
- Testing
- Free connective tissue graft without an epithelial collar, Free connective tissue graft with epithelial collar
- Where
- Russia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Peri-Implant Health, Peri-Implant Tissues
Volumetric Analysis of Peri-Implant Soft Tissue Changes Between Polyethereketone(PEEK) Anatomic Healing Abutments and Standard Healing Abutments in Posterior Single Implant Restorations
This prospective randomized clinical trial will evaluate the clinical outcomes of the implant crown fabricated with standard scan body (control) and polyetheretherketone (PEEK) anatomic healing abutment (test).
- Conditions
- Peri-Implant Health, Peri-Implant Tissues, Soft Tissue Augmentation at Dental Implants
- Trial name
- anatomic (NCT07624331)
- Testing
- AHA PEEK, standard healing abutment
- Where
- Malaysia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- DR NUR HAFIZAH KAMAR AFFENDI