Clinical trials: Peri-implantitis
Peri-Implant Health, Peri-Implantitis and Peri-implant Mucositis
Monitoring of Implant Diseases: Diagnosis and Monitoring With aMMP-8 Test Technology
68 patients underwent the aMMP-8 chair-side test as well as clinical traditional measurement methods. Those who had one or more implants in their mouth were selected as patients.
- Trial name
- IMP_TRE (NCT06761521)
- Testing
- Peri-Implantitis and Peri-implant mucositis
- Where
- Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hanna Lahteenmaki
Peri-implantitis
Expression of Epithelial-Mesenchymal Transition Associated Markers in Peri-implant Tissues
Peri-implantitis is an inflammation of bacterial etiology characterized by inflammation of mucous membranes and bone loss around the dental implant.
- Trial name
- NCT05832541
- Where
- Iraq
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Dental Implant, Peri-Implantitis
Alveolar Ridge Sequelae Due to Peri-implantitis: a Retrospective Observational Study
The scientific evidence available at present regarding the alterations suffered by the alveolar ridge after the explantation of implants that have been considered to be abandoned due to periimplantitis, as well as the remaining…
- Conditions
- Dental Implant, Peri-Implantitis, Bone Remodeling
- Trial name
- NCT04534361
- Testing
- CBCT measurements
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Peri-Implantitis, Dental Implant Failed
Assessment of the Effects of Different Implant Abutment Occluding Materials on Dental Implant Health Parameters and Microbiology
The primary purpose of this study is to determine what effect, if any, do different dental materials used to seal the prosthetic screw channels of implant supported restorations have on dental implant health parameters and…
- Conditions
- Peri-Implantitis, Dental Implant Failed, Dental Implant Failure Nos
- Trial name
- NCT02625597
- Testing
- Cotton Pellet, Polytetrafluoroethylene Tape, Synthetic Foam
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Peri-Implantitis, Periodontal Diseases
Microbiota Around Periodontal Teeth and Implants Affected by Peri-implant Disease.
The purpose of the study was to evaluate, from a microbiological point of view, microbiota around teeth and implants in the same patient affected by periodontal disease and peri-implant disease, all compared with a healthy tooth.
- Trial name
- NCT03407911
- Testing
- Harvested
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Universitaria Policlinico Vittorio Emanuele
Peri-Implantitis, Soft Tissue
Association of Keratinised Mucosa Around Implants and Teeth With Peri-implant/Periodontal Disease and Soft Tissue Conditioning
Lack of keratinised mucosa around dental implants and teeth is associated with plaque accumulation and worse tissue conditions. However, there is lack of data on the influence of the presence/lack of keratinised mucosa on the…
- Conditions
- Peri-Implantitis, Soft Tissue, Bone Gain
- Trial name
- NCT03501537
- Testing
- Free gingival graft obtained from the palate and debridement of the peri-implant lesion
- Where
- Spain
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Obesity, Peri-implant Inflammation
The Effect of Obesity on Oral Peri-implant Health - A Cross-Sectional Study
In recent years, greater emphasis has been placed on the link between oral and systemic health. Obesity, a growing medical problem worldwide, has been associated with multiple chronic inflammatory diseases such as diabetes…
- Conditions
- Obesity, Peri-implant Inflammation, Peri-implantitis
- Trial name
- NCT01878071
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Dental Implants, Aggressive Periodontitis
Impact of Periodontitis Grading on Peri-Implant Clinical and Bone Health: A 60-Month Prospective Study
This prospective cohort study evaluated the effect of periodontitis grading on peri-implant clinical and radiographic outcomes over a 60-month follow-up.
- Conditions
- Dental Implants, Aggressive Periodontitis, Chronic Periodontitis, Staging
- Trial name
- NCT07671456
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Peri-Implantitis, Bone Resorption
Surgical Treatment of Peri-implantitis With Adjunctive Application of Platelet Rich Fibrin (PRF)
Platelet-rich fibrin (PRF) is a second-generation platelet concentrate used for tissue and bone regeneration. PRF releases growth factors such as TGF-β, PDGF, VEGF, IGF, and FGF, which are known to promote wound healing and bone…
- Conditions
- Peri-Implantitis, Bone Resorption, Platelet-Rich Fibrin
- Trial name
- PRF (NCT06679283)
- Testing
- Open flap debridement with a chemo-electric device + PRF, Open flap debridement with a chemo-electric device alone (control)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Bern
Tooth Loss, Bone Loss, Alveolar
Immediate Implant Outcomes With and Without Bone Augmentation
To evaluate immediate implant placement feasibility and esthetic outcomes in severely damaged sockets that received simultaneously bone reconstruction (cortical bone shield) and implant placement versus intact sockets that needed…
- Conditions
- Tooth Loss, Bone Loss, Alveolar, Dental Diseases, Dental Trauma
- Trial name
- NCT05157009
- Testing
- implant placement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Verdugo, Fernando, DDS
Peri-Implantitis
Soft Tissue Assessment in Screw-Retained Maxillary Complete Denture With Electric Welded Framework Versus Casted
comparing the changes in the soft tissue around the implants that will be joined by a metal framework either with electric welding or with the conventional casting method
- Trial name
- NCT04543864
- Testing
- Electric intraoral welding device, casting
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Peri-Implantitis
Peri-implantitis and MMP-8
Peri-implantitis is defined as the pathological condition around dental implants characterized by inflammation in the peri-implant mucosa and progressive bone loss, eventually leading to implant loss.
- Trial name
- NCT05711407
- Testing
- Gene Polymorphisms of MMP-8
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Vitamin D Deficiency, Osseointegration Failure of Dental Implant
Vitamin-D Insufficiency and Implants
Vitamin D is important for bone health, immune function, and inflammation, along with dental implant success. The study aimed to assess bone markers and cytokine levels in patients with and without vitamin D insufficiency to…
- Conditions
- Vitamin D Deficiency, Osseointegration Failure of Dental Implant, Peri-Implantitis
- Trial name
- NCT06452251
- Testing
- OPG, OC, RANKL, IL-10, IL-1β, Ca, TNF-α and Caspase-1 ELISA, Resonance Frequency Analysis, Periodontal clinical examination
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Vesile Elif Toy
Peri-Implantitis
Resective Surgical Treatment of Peri-implantitis.
Surgical treatment of peri-implantitis can be regenerative or resective, depending on defect configuration. The aim of resective therapy of peri-implantitis is to reduce the severity of soft tissue inflammation and stabilize…
- Trial name
- NCT04337645
- Testing
- surgical treatment of peri-implantitis
- Where
- Serbia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Peri-Implantitis, Peri-implant Mucositis
Peri-implant Conditions Mimic Periodontal Conditions
Except for patients with referred clinical bruxism and uncontrolled medical conditions, the study included 123 implants with implanted fixed prostheses that had lasted at least six months after functional prosthetic loading.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Peri-implant Health, Periodontitis
- Trial name
- NCT06128850
- Testing
- disease
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Periimplantitis, Oral Surgery
Impact of Buccal Bone Thickness on Pathological Peri-implant Bone Loss: A 3-year Prospective Cohort Study
Implant placement may trigger bone trauma, which might result in 3-dimensional bone changes. While the process of peri-implant disease is not well understood, implant position within the bony structure might play a role.
- Trial name
- NCT02939222
- Testing
- Implant placement
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Peri-Implantitis
Metronidazole as an Adjunct of Non- Surgical Treatment of Peri-implantitis
The use of systemic antibiotics as and adjunct to non-surgical peri-implant therapy may be an improvement in comparison to these therapies alone.
- Trial name
- NCT03564301
- Testing
- Metronidazole 250 MG
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Juan Blanco Carrión
Peri-implantitis
Surface Decontamination in Treatment of Peri-Implantitis
Peri-implantitis represents a major biological complication of implant dentistry with reported prevalence of up to 47% of implants.
- Trial name
- NCT03114956
- Testing
- Gauze, Titanium brush, Air powder abrasion
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Southern California
Peri-Implantitis and Peri-implant Mucositis, Hypoxia
Analysis of HIF-1α, MDA, and GPX4 in Peri-Implant Crevicular Fluid
Peri-implant diseases, such as peri-implant mucositis and peri-implantitis, are inflammatory conditions that affect the tissues surrounding dental implants. If untreated, these diseases can lead to bone loss and implant failure.
- Conditions
- Peri-Implantitis and Peri-implant Mucositis, Hypoxia, Ferroptosis
- Trial name
- NCT06863116
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ege University
Peri-implantitis
Surgical Protocol for Peri-implantitis Treatment
Peri-implant diseases are common post-restorative complications in implant rehabilitations and they occur with an incidence of 12-43%.
- Trial name
- NCT03801187
- Testing
- chlorhexidine, Er:YAG laser, Air-Powder
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele