Clinical trials: Peri-operative Mortality
Medical Device
Impact on the Time to Diagnosis of Serious Postoperative Complications by a Controlled Connected Medical Device
Post-operative mortality in case of scheduled surgery is 3% in France (Lancet 2013) mainly due to cardiovascular or respiratory complications, by decompensation of pre-existing pathologies.
- Trial name
- SMARTANGEL (NCT05380310)
- Testing
- Active "SMART ANGEL" solution, Inactive "SMART ANGEL" solution
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Medical Device
Technical Capabilities of the "SMART ANGEL Intra-hospital" System 's Connected Medical Device (CMD)
Post-operative mortality in case of scheduled surgery is 3% in France (Lancet 2013) mainly due to cardiovascular or respiratory complications, by decompensation of pre-existing pathologies.
- Trial name
- SMART-METRO (NCT04668807)
- Testing
- Connected Medical Device, Traditional transmission system
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hyperglycemia
The Association Between Peri-Operative Hyperglycemia and Major Morbidity and Mortality
Surgery induces a stress effect on the body partially through a catabolic energy state. In turn, glucose levels may rise to levels which have been associated with major morbidity (Golden, 1999) and mortality (Ouattara, 2005).
- Trial name
- NCT00487162
- Testing
- intensive glycemic control, conventional glycemic control
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Respiratory Failure, Acute Respiratory Failure Requiring Intubation
Intra-operative Inspiratory Oxygen Fraction and Postoperative Respiratory Complications
Respiratory complications represent the second most frequent type of postoperative complications with an incidence estimated to range from 2.0% to 7.9% It has been shown that intra-operative protective ventilation is associated…
- Conditions
- Respiratory Failure, Acute Respiratory Failure Requiring Intubation, Pulmonary Edema, Pneumonia
- Trial name
- NCT02399878
- Testing
- Inspiratory oxygen
- Volunteers
- 70,000 people
- Sponsor
- Massachusetts General Hospital
Postoperative Mortality
Evaluation of Co-morbidity Scales
Peri-operative mortality depends on the patient's co-morbidities. ASA Physical Status (American Society of Anesthesiology) is the most commonly scale to assess this parameter and has yet been repeatedly criticized in the past for…
- Trial name
- Ko-MoSkau (NCT01810133)
- Where
- Germany
- Volunteers
- 230,034 people
- Sponsor
- Charite University, Berlin, Germany
Liver Injury
Non-Operative Management of High Grade Blunt Hepatic Injury: Clinical Complications and the Role of Collateral Damage
Little is known about the role of collateral damage in patients with high grade liver injuries (LI). This retrospective single centre study investigates the safety of the non-operative management of patients with high grade blunt…
- Trial name
- NOMLI (NCT00694499)
- Where
- Switzerland
- Volunteers
- 183 people
- Sponsor
- University of Bern
Peri-operative Mortality
Open Repair Versus Branched Endograft Repair for Treatment of Residual Chronic Aortic Arch Dissection During Follow-up After Open Type A Acute Ascending Aorta Replacement: Results From an International Multicenter Study.
This study aims to evaluate peri-operative mortality and main post-operative complications (for example cardiovascular, respiratory and renal) in patients treated with frozen elephant trunk techinque.
- Trial name
- NCT04014907
- Testing
- Frozen Elephant Trunk Technique
- Where
- Italy
- Volunteers
- 170 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Peri-operative Mortality, Coronary Artery Calcium
Coronary Assessment for Mortality Prediction
The study will investigate whether the presence of coronary artery calcium as demonstrated on pre-operative, thoracic staging Computed Tomography (CT) is an independent risk factor for 90 day mortality in patients undergoing…
- Trial name
- CAMP (NCT02208648)
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- University Hospital Plymouth NHS Trust
Intra-Abdominal Infections, Intestinal Obstruction
Capillary Leak Index as a Prognostic Indicator for Post-Operative Abdominal Sepsis in Critically Ill Patients
In this study the investigators going to evaluate the "CLI" as an early prognostic indicator for post-operative abdominal sepsis in critically ill patients.
- Conditions
- Intra-Abdominal Infections, Intestinal Obstruction, Appendicitis Acute, Perforated Viscus
- Trial name
- CLI (NCT06901544)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Peri-operative Mortality
Mortality and Complications in Endovascular Procedures Performed With New Generation Low-profile Devices
The aim of this study is to observe mortality and complications in procedures in which are used new generation low-profile endoprothesis.
- Trial name
- NCT04016545
- Testing
- Low profile endoprothesis (Navion Medtronic, NBS Low Profile Bolton Terumo)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Perioperative/Postoperative Complications, Morality
Estimated Oxygen Extraction Versus Dynamic Parameters for Perioperative Hemodynamic Optimization
The aim of the study is to evaluate the complications rate of high risk patients undergoing non-cardiac surgery that receive two different protocols of hemodynamic optimization.
- Trial name
- NCT04053595
- Testing
- Dynamic parameters of fluid responsiveness protocol, Estimated oxygen extraction protocol
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Università Politecnica delle Marche