Clinical trials: Periampullary Adenocarcinoma
Periampullary Adenocarcinoma
Comparing Laparoscopic and Open Pancreaticoduodenectomy for Nonpancreatic Periampullary Adenocarcinomas
The aim of this study was to evaluate the outcomes of LPD versus OPD in non-pancreatic periampullary adenocarcinoma
- Trial name
- NPPC (NCT05788029)
- Testing
- laparoscopic pancreaticoduodenectomy, open pancreaticoduodenectomy
- Where
- China
- Volunteers
- 212 people
- Sponsor
- Tongji Hospital
Periampullary Cancer, Pancreatic Cancer
Comparison Between Endoscopic Stenting and Cholecystojejunostomy for PreoperativeDrainage Before Pancreaticoduodenectomy
Periampullary carcinoma and carcinoma head of pancreas are common causes of obstruction at the lower end of the common bile duct.
- Trial name
- NCT01913275
- Testing
- Endoscopic stenting, cholecystojejunostomy
- Where
- India
- Sponsor
- All India Institute of Medical Sciences
Pancreatic Cancer, Periampullary Cancer
Preoperative Detection of Lymph Node Metastases in Pancreatic and Periampullary Carcinoma Using USPIO MRI
Adenocarcinoma's of the pancreas and periampullary region (distal bile duct, ampulla of Vater and duodenum) are cancers with a poor survival.
- Trial name
- NANO-PANC (NCT04311047)
- Testing
- USPIO-enhanced MRI
- Where
- Netherlands
- Volunteers
- 26 people
- Sponsor
- Radboud University Medical Center
Pancreatic Neoplasms
Respiratory-gated Stereotactic Body Radiation Therapy for Adenocarcinoma of the Pancreas or Periampullary Region
This is a single center, single arm unblinded prospective study of the safety of pancreatic stereotactic body radiation therapy (SBRT) in patients with unresectable, borderline resectable, or recurrent pancreatic/periampullary…
- Trial name
- NCT02780648
- Testing
- Stereotactic Body Radiation
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Indiana University
Pancreatic Cancer, Pancreatic Adenocarcinoma
EUS BD vs ERCP TP for Pancreatic Cancer
This Endoscopic Ultrasound guided Biliary Drainage (EUS-BD) vs. Endoscopic Retrograde Cholangiopancreatography (ERCP-TP) trial (BILPAL) is a randomized controlled multicenter trial that will provide evidence whether or not…
- Conditions
- Pancreatic Cancer, Pancreatic Adenocarcinoma, Biliary Tract Neoplasms, Biliary Duct Obstruction
- Trial name
- BILPAL (NCT03063554)
- Testing
- Endoscopic Ultrasound Guided Biliary Drainage, ERCP
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Weill Medical College of Cornell University
Adult Primary Cholangiocellular Carcinoma, Advanced Adult Primary Liver Cancer
Cediranib Maleate and Combination Chemotherapy in Treating Patients With Advanced Biliary Cancers
This phase II trial is studying how well giving cediranib maleate together with combination chemotherapy works in treating patients with advanced biliary cancers.
- Conditions
- Adult Primary Cholangiocellular Carcinoma, Advanced Adult Primary Liver Cancer, Cholangiocarcinoma of the Extrahepatic Bile Duct, Cholangiocarcinoma of the Gallbladder
- Trial name
- NCT01229111
- Testing
- cediranib maleate, oxaliplatin, leucovorin calcium
- Where
- 7 sites in United States
- Volunteers
- 14 people
- Sponsor
- National Cancer Institute (NCI)
Pancreatic Neoplasm, Pancreatic Periampullary Cancer
The Effect of Application of TachoSil® in Pancreatoduodenectomy
Fibrinogen/thrombin-coated collagen patch (TachoSil®) is known to have the effect of strengthening tissue anastomosis and promoting suturing to prevent leakage.
- Conditions
- Pancreatic Neoplasm, Pancreatic Periampullary Cancer, Pancreatic Bordeline Tumor
- Trial name
- NCT03269955
- Testing
- Fibrinogen/thrombin-coated collagen patch
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Asan Medical Center
Periampullary Adenocarcinoma, Periampullary Cancer
Chemotherapy, Host Response and Molecular Dynamics in Periampullary Cancer
The CHAMP (Chemotherapy, Host response And Molecular dynamics in Periampullary cancer) study is a prospective, single-arm observational study that started Sept 1 2018.
- Conditions
- Periampullary Adenocarcinoma, Periampullary Cancer, Pancreatic Cancer
- Trial name
- CHAMP (NCT03724994)
- Testing
- Gemcitabine
- Where
- Sweden
- Volunteers
- 201 people
- Sponsor
- Lund University
Pancreas Cancer, Pancreas Neoplasm
The Role of the Human Microbiome in Patients After Pancreatic Resection.
The goal of this observational study is to classify patients that undergo pancreatic resection for presumed pancreatic or periampullary malignancy into high and low risk groups for postoperative complications based on…
- Conditions
- Pancreas Cancer, Pancreas Neoplasm, Pancreas Adenocarcinoma, Periampullary Cancer
- Trial name
- MiPac (NCT06381882)
- Testing
- Pancreatic resection
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- St. Antonius Hospital
Hepatocellular Carcinoma, Cholangiocellular Carcinoma
Gemcitabine, Oxaliplatin, Tarceva &/or Cisplatin in HCC & Biliary Tree Cancers
This is a single arm phase II trial of Gemcitabine and Oxaliplatin (Gem-Ox) with Erlotinib (Tarceva) for the treatment of hepatocellular carcinoma (HCC) and biliary tree cancer (BTC) patients with platelet counts 100,000/µL.
- Conditions
- Hepatocellular Carcinoma, Cholangiocellular Carcinoma, Cholangiocarcinoma of the Extrahepatic Bile Duct, Bile Duct Cancer
- Trial name
- Gem-ox (NCT00832637)
- Testing
- Cisplatin, Erlotinib, Gemcitabine
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- New Mexico Cancer Research Alliance
Pancreatic Cancer, Cholangiocarcinoma
Margin Status After Pancreaticoduodenectomy for Cancer
This multicentric prospective randomized controlled trial (RCT) compares the Leeds Pathology Protocol (LEEPP) with other "conventional" pathological protocol of PD specimen for periampullary cancer.
- Conditions
- Pancreatic Cancer, Cholangiocarcinoma, Ampullary Cancer
- Trial name
- NCT03267966
- Testing
- Leeds Pathology Protocol (LEEPP)
- Volunteers
- 168 people
- Sponsor
- Campus Bio-Medico University
Pancreaticoduodenectomy, Postoperative Pancreatic Fistula
Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate
This randomized controlled trial investigates the safety and efficacy of injecting N-butyl-2- cyanoacrylate (Histoacryl®) into the pancreatic parenchyma during pancreaticoduodenectomy (PD) to enhance the security of the…
- Conditions
- Pancreaticoduodenectomy, Postoperative Pancreatic Fistula, Pancreas Cancer, Periampullary Cancer
- Trial name
- NBCA (NCT07230509)
- Testing
- Pancreatic parenchymal injection of N-butyl-2- cyanoacrylate(Histoacryl®)Injection Group., Standard Pancreaticojejunostomy
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Minia University
Pancreatic Fistula, Pancreas Cancer
Reinforced Pancreaticojejunostomy With or Without glubran2
Pancreatic fistula is one of the most serious complication after pancreatoduodenectomy. To reduce pancreatic fistula, many authors recommend different techniques in pancreatojejunostomy.
- Conditions
- Pancreatic Fistula, Pancreas Cancer, Periampullary Carcinoma, Pancreatic Ductal Adenocarcinoma
- Trial name
- NCT06756074
- Testing
- Reinforced pancreaticojejunostomy with tissue adhesive glue modified cyanoacrylate (glubran 2), Pancreaticojejunostomy without tissue adhesive glue modified cyanoacrylate (glubran 2)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
Periampullary Cancer, Borderline Malignancy Tumor
The Effect of ERAS on Pancreaticoduodenectomy (v2.0)
Enhanced Recovery After Surgery (ERAS) is not a program that aims to reduce postoperative hospital stay, but the multimodal strategies that aim to attenuate the loss of, and improve the restoration of, functional capacity after…
- Trial name
- NCT06009224
- Testing
- ERAS perioperative management
- Where
- South Korea
- Volunteers
- 334 people
- Sponsor
- Asan Medical Center
Pancreatic Cancer, Pancreatic Fistula
Laparoscopic Pancreaticoduodenectomy
Laparoscopic pancreaticoduodenectomy was first performed by Garner and Pomp in 1994. This is a technically difficult, time consuming and high rate of complication procedure.
- Conditions
- Pancreatic Cancer, Pancreatic Fistula, Periampullary Cancer
- Trial name
- LPD (NCT07009119)
- Testing
- laparoscopic Pancreaticoduodenectomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Extrahepatic Bile Duct Cancer, Gallbladder Cancer
Gemcitabine Hydrochloride, Oxaliplatin, and Erlotinib Hydrochloride in Treating Patients With Advanced Biliary Tract Cancer, Pancreatic Cancer, Duodenal Cancer, or Ampullary Cancer
RATIONALE: Drugs used in chemotherapy, such as gemcitabine hydrochloride and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Liver Cancer, Pancreatic Cancer
- Trial name
- NCT00987766
- Testing
- erlotinib hydrochloride, gemcitabine hydrochloride, oxaliplatin
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Pancreas Cancer, Pancreas Neoplasm
Prognostic Factors in Periampullary Tumors and Cysts
The project aims at analysing prognostic and predictive factors involved in diagnostics and surgical treatment of cysts and tumors in the pancreas and periampullary region using both clinical data and blood and tissue samples for…
- Conditions
- Pancreas Cancer, Pancreas Neoplasm, Pancreas Cyst, Pancreatic Fistula
- Trial name
- NCT05155878
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- Umeå University
Periampullary Carcinoma Nos
Effect of Probiotics in Patients Undergoing Surgery for Periampullary Neoplasms
The purpose of this study is to evaluate the effect of the probiotic use in patients with periampullary cancers undergone curative or palliative treatment considering nutritional status, postoperative complications, infection…
- Trial name
- NCT01468779
- Testing
- Probiotics, Sugar pill
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Biliary Tract Cancer, Periampullary Adenocarcinoma
SOX Sequential S-1 in Advanced Biliary Tract Carcinoma（BTC）and Pancreatic Cancer
This is an exploratory, single-armed, open label study on the efficacy and safety of sequential S-1 therapy after SOX in unresectable metastatic or locally advanced biliary system or periampullary cancer or pancreatic cancer…
- Conditions
- Biliary Tract Cancer, Periampullary Adenocarcinoma, Pancreatic Cancer
- Trial name
- NCT01811277
- Testing
- SOX sequential S-1
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University
Pancreatic Cancer, Periampullary Adenocarcinoma
Palliative Stereotactic Radiation for Pancreatic or Periampullary Adenocarcinoma
The investigators are looking to see if a certain dose of stereotactic body radiation therapy (SBRT) may be a viable treatment option for recurrent or residual pancreatic or periampullary adenocarcinoma.
- Trial name
- NCT01781728
- Testing
- Stereotactic Body Radiation Therapy (SBRT)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins