Clinical trials: Peribulbar Anesthesia
Cataract, Mydriasis
Subconjunctival Atropine and Intracameral Epinephrine for Pupil Dilation in Phacoemulsification
Mydriatic eye drops are routinely used before phacoemulsification but they are not free of drawbacks. Several alternatives were tried to overcome their limitations.
- Conditions
- Cataract, Mydriasis, Adverse Drug Event
- Trial name
- NCT03638726
- Testing
- Atropine sulfate and epinephrine, Topical cyclopentolate and phenylephrine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Dar El Oyoun Hospital
Anesthesia
Clonidine Added Lidocaine in Intraocular Pressure and Hemodynamics Ocular in Sub-Tenon's and Peribulbar Anesthesia
Regional anesthesia in orbit can reduce ocular blood flow, increase in intraocular pressure (IOP) or the pharmacological action of local anesthetics.
- Trial name
- NCT02733757
- Testing
- Clonidine
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Vitreoretinal Surgeries, Postoperative Nausea and Vomiting
Different Peribulbar Blocks With SPI-guided Anaesthesia for VRS (P&MSPIVRS)
The aim of this randomized trial is to assess the efficacy of preventive analgesia using different peribulbar blocks (PBB) under SPI-guided anaesthesia for vitreoretinal surgery (VRS), presence of PONV (postoperative nausea and…
- Conditions
- Vitreoretinal Surgeries, Postoperative Nausea and Vomiting, Postoperative Pain, Oculocardiac Reflex
- Trial name
- PBBVRS (NCT03413371)
- Testing
- paracetamol, 0,5 % bupivacaine with of 2% lidocaine, 1 % Ropivacaine
- Where
- Poland
- Volunteers
- 184 people
- Sponsor
- Medical University of Silesia
Ophthalmic Surgery, Parabulbar Block
Anaesthesia for Ophthalmic Surgery: How "Retro" is the Peribulbar Block?
Ophthalmic surgery on the posterior section of the eye can either be performed under general anaesthesia or under local aneasthesia. The local anaesthesia is performed by injecting local anaesthetics behind the eye.
- Trial name
- NCT01258959
- Testing
- Ultrasound detection of local anesthetics spread
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Sunnybrook Health Sciences Centre
Vitreoretinal Surgeries, Postoperative Nausea and Vomiting
SPI-directed Analgesia for Vitreoretinal Surgeries
The aim of this randomized trial is to assess the efficacy of SPI-directed analgesia for vitreoretinal surgeries (VRS), presence of PONV and oculocardiac reflex (OCR) and compare Numerical Rating Scale (NRS) with Surgical Pleth…
- Conditions
- Vitreoretinal Surgeries, Postoperative Nausea and Vomiting, Postoperative Pain
- Trial name
- SPIVS (NCT02973581)
- Testing
- Metamizol, Acetaminophen, 0,5 % bupivacaine with of 2% lidocaine
- Where
- Poland
- Volunteers
- 176 people
- Sponsor
- Medical University of Silesia
Anesthesia, Local
Study of Two-step Anesthesia in Posterior Vitrectomy
A prospective, randomised, single-masked comparison of local anaesthetic approaches including topical anesthesia combined sub-conjunctival anesthesia(two-step anesthesia) for minimally invasive vitrectomy（TAMIV）vs peribulbar…
- Trial name
- NCT03577574
- Testing
- retrobulbar anesthesia, peribulbar anesthesia, two step anesthesia
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Anesthesia, Local
Peribulbar Block: Lidocaine-bupivacaine vs Lidocaine-bupivacaine-fentanyl
Ophthalmological procedures such as cataract extraction can be carried out with a peribulbar block (PBB). The advantages of this anesthetic technique include a lower incidence of coughing, unwanted movements and emesis during…
- Trial name
- NCT03713762
- Testing
- peribulbar block 1 lidocaine/bupivacaine, peribulbar block 2 lidocaine/bupivacaine/fentanyl
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centro Medico Docente la Trinidad
Quality of Ocular Akinesia (Onset and Duration)
Efficacy and Safety of Adding Atracurium to Percaruncular Block for High Myopes Undergoing Cataract Surgery
There are several local anesthetic techniques available for cataract surgery and the choice depends on patient, surgical and operator factors.
- Trial name
- NCT03243500
- Testing
- Atracurium, Lidocaine 2%, Bupivacaine 0.5%
- Where
- Egypt
- Volunteers
- 91 people
- Sponsor
- Kasr El Aini Hospital
Dexmedetomidine, Cataract Surgery
Dexmedetomidine in Topical Versus Peribulbar Anesthesia for Cataract Surgery
The aim of this study is to compare efficacy of dexmedetomidine as an additive to topical versus peribulbar anesthesia for cataract surgery
- Conditions
- Dexmedetomidine, Cataract Surgery, Peribulbar, Anesthesia
- Trial name
- NCT05692167
- Testing
- Topical dexmedetomidine, Reginal dexmedetomidine
- Where
- Egypt
- Volunteers
- 94 people
- Sponsor
- Kafrelsheikh University
Strabismus, Regional Anesthesia Morbidity
Peribulbar Rocuronium in Adult Strabismus Surgery
This is a prospective randomized clinical study that will be carried on adult patients aged from 21-60 years and presented for strabismus surgery under peribulbar anesthesia.
- Conditions
- Strabismus, Regional Anesthesia Morbidity, Rocuronium
- Trial name
- NCT04821817
- Testing
- Normal saline, Rocuronium
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Tanta University
Patient, Satisfaction
The Sedative Effects of Dexmedetomidine VS Propofol During Peribulbar Anesthesia in Patients Undergoing Vitrectomy Surgery
The aim of the work to compare the Sedative Effects of Dexmedetomidine and Propofol during peribulbar anesthesia in patients undergoing vitrectomy surgery on hemodynamic, respiratory parameters, recovery profile, analgesic…
- Trial name
- NCT06369103
- Testing
- Dexmedetomidine, Propofol
- Where
- Egypt
- Volunteers
- 420 people
- Sponsor
- Beni-Suef University
Anaesthesia, Cataract
A Comparison of One-site and Two-site Peribulbar Anaesthesia for Cataract Surgery at Kaduna, Nigeria
The aim of the study was to compare the efficacy and safety of single injection peribulbar anaesthesia against the classic double injection technique.
- Trial name
- NCT02150460
- Testing
- One-site peribulbar injection, Two- site peribulbar injection
- Where
- Nigeria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Eye Centre, Kaduna
Pediatric Squint Surgeries
Comparing General Anesthesia With Single Injection Peribulbar Block With 3 Different Drugs
To compare the effect of the used local anesthetics in this study on decreasing the incidence of oculocardiac reflex . To evaluate the efficacy of Articaine 4 % , mepivacaine 3% and lidocaine 2% regarding post- operative…
- Trial name
- NCT05728151
- Testing
- Articaine and Epinephrine Only Product, levobupivacaine, mepivacaine
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Research Institute of Ophthalmology, Egypt
Proliferative Diabetic Retinopathy
Pain Management During Panretinal Photocoagulation for Diabetic Retinopathy: Safety and Efficacy of Peribulbar Anesthesia
The purpose of this study was to compare two different anesthesia methods for pain control during panretinal photocoagulation (PRP), a type of laser surgery that treats proliferative diabetic retinopathy (PDR).
- Trial name
- NCT07640256
- Testing
- Peribulbar anesthesia with 0.5% bupivacaine and 2% lidocaine, Tetracaine 5% drops
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Asociación para Evitar la Ceguera en México
Retinal Disease, Diabetic Retinopathy
Pain During Pars Plana Vitrectomy With Sub-tenon Anesthesia
Vitreoretinal surgery has evolved to less invasive procedures, and it is used to treat a wide range of diseases. So anesthesia for vitreoretinal procedures has evolved, promoting adequate analgesia while reducing risks to the…
- Conditions
- Retinal Disease, Diabetic Retinopathy, Maculopathy
- Trial name
- NCT03902925
- Testing
- Topical lidocaine 2% jelly plus sub-tenon ropivacaine 10% injection, Peribulbar injection
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- University of Sao Paulo
Indication for Surgery of the Posterior Segment Under Locoregional Anaesthesia
Clonidine - Ropivacaine in Peribulbar Anesthesia
This is a study conducted in 60 patients, randomly assigned to one of two groups of 30: the first will receive ropivacaine alone and the second will receive the association ropivacaine/clonidine.
- Trial name
- CRAPO (NCT01963299)
- Testing
- 5 ml Ropivacaine 10% + physiological saline, 5 ml Ropivacaine 10% + Clonidine 1 µg/kg
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Anesthesia, Local, Ophthalmopathy
Comparison Between Peribulbar And Sub-tenon Blocks on Oculocardiac Reflex (OCR) During Pediatric Strabismus Surgery
The aim of this study is to compare between peribulbar block and subtenon block as an adjunct to general anesthesia in children undergoing strabismus surgery on oculocardiac reflex (OCR), post-operative analgesia and…
- Conditions
- Anesthesia, Local, Ophthalmopathy, Strabismus, Pediatric ALL
- Trial name
- NCT06293586
- Testing
- peribulbar block, sub-tenon block, Paracetamol
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hemodynamic Effect, Dexmedetomidine
Hemodynamic Effect of Dexmedetomidine Versus Magnesium Sulphate as an Adjuvant to Lidocaine in Preemptive Peribulbar Block in Patients Undergoing Dacryocystorhinostomy Under General Anesthesia
This study aims to compare the hemodynamic effect of dexmedetomidine and magnesium sulphate as an adjuvant to lidocaine in preemptive peribulbar block in patients undergoing Dacryocystorhinostomy (DCR) under general anaesthesia…
- Conditions
- Hemodynamic Effect, Dexmedetomidine, Magnesium Sulphate, Lidocaine
- Trial name
- NCT07675616
- Testing
- Lidocaine + Dexmedetomidine, Lidocaine + Magnesium sulphate, Lidocaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Vitreoretinal Surgeries, Local Anesthesia
Comparative Study Between Dexmedetomidine & Neostigmine as an Adjuvant to Local Anesthetic Mixture in Peribulbar Block in Vitreoretinal Surgeries
The majority of patients undergoing ophthalmic surgeries are elderly, with multiple chronic diseases, with increased risk of morbidity and mortality under general anesthesia.
- Trial name
- NCT06501352
- Testing
- Dexmedetomidine, Neostigmine, Saline
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- Ain Shams University
Peribulbar Anesthesia
Atracurium Versus Atracurium and Magnesium Sulphate As Adjuvants to Local Anesthetic
To evaluate the effects of adding magnesium sulfate to atracurium with local anesthetic mixture on akinesia of globe and eyelid regarding onset and duration in cataract surgery using peribulbar technique
- Trial name
- NCT06600945
- Testing
- Cataract surgery
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Dalia yousry Mohamed elsayed