Clinical trials: Peribulbar Block
Vitreoretinal Surgeries, Local Anesthesia
Comparative Study Between Dexmedetomidine & Neostigmine as an Adjuvant to Local Anesthetic Mixture in Peribulbar Block in Vitreoretinal Surgeries
The majority of patients undergoing ophthalmic surgeries are elderly, with multiple chronic diseases, with increased risk of morbidity and mortality under general anesthesia.
- Trial name
- NCT06501352
- Testing
- Dexmedetomidine, Neostigmine, Saline
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- Ain Shams University
Quality of Ocular Akinesia (Onset and Duration)
Efficacy and Safety of Adding Atracurium to Percaruncular Block for High Myopes Undergoing Cataract Surgery
There are several local anesthetic techniques available for cataract surgery and the choice depends on patient, surgical and operator factors.
- Trial name
- NCT03243500
- Testing
- Atracurium, Lidocaine 2%, Bupivacaine 0.5%
- Where
- Egypt
- Volunteers
- 91 people
- Sponsor
- Kasr El Aini Hospital
Nalbuphine,Fentanyl and Local Anesthetic Mixture
Nalbuphine, Fentanyl and no Additive to Local Anaesthetic Mixture
Nalbuphine has been used as an adjuvant to bupivacaine in intrathecal,epidural, caudal anesthesia and peripheral nerve blocks showing an increase in the efficacy and the duration of postoperative analgesia.
- Trial name
- NCT03824665
- Testing
- Nalbuphine Group, Fentanyl Group, Control Group
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain, Cataract
Midazolam Additive to Local Anesthetic in Peribulbar Block
Regional eye blocks are usually preferred for ophthalmic procedures. Peribulbar block (PBB) is a safe alternative for patients undergoing cataract surgery.
- Conditions
- Postoperative Pain, Cataract, Local Anaesthetic Complication, Midazolam
- Trial name
- NCT03397069
- Testing
- Peribulbar block (control), Peribulbar block(M1), Peribulbar block(M2)
- Where
- Saudi Arabia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Al Jedaani Hospital
Anesthesia
Clonidine Added Lidocaine in Intraocular Pressure and Hemodynamics Ocular in Sub-Tenon's and Peribulbar Anesthesia
Regional anesthesia in orbit can reduce ocular blood flow, increase in intraocular pressure (IOP) or the pharmacological action of local anesthetics.
- Trial name
- NCT02733757
- Testing
- Clonidine
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Vitreoretinal Surgeries, Postoperative Nausea and Vomiting
SPI-directed Analgesia for Vitreoretinal Surgeries
The aim of this randomized trial is to assess the efficacy of SPI-directed analgesia for vitreoretinal surgeries (VRS), presence of PONV and oculocardiac reflex (OCR) and compare Numerical Rating Scale (NRS) with Surgical Pleth…
- Conditions
- Vitreoretinal Surgeries, Postoperative Nausea and Vomiting, Postoperative Pain
- Trial name
- SPIVS (NCT02973581)
- Testing
- Metamizol, Acetaminophen, 0,5 % bupivacaine with of 2% lidocaine
- Where
- Poland
- Volunteers
- 176 people
- Sponsor
- Medical University of Silesia
Nalbuphine as an Adjuvant to L. A in Peribulbar Block for Cataract Surgery
Nalbuphine as an Adjuvant to Local Anaesthetic Mixture in Peribulbar Cataract Surgery
Nalbuphine has been used as an adjuvant to bupivacaine in intrathecal, epidural, caudal anesthesia and peripheral nerve blocks showing an increase in the efficacy and the duration of postoperative analgesia.The aim of this study…
- Trial name
- NCT03436836
- Testing
- Nalbuphine, lidocaine, bupivacaine, hyaluronidase , saline, lidocaine, bupivacaine , hyaluronidase
- Where
- 2 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Fentanyl, Ketorolac
Fentanyl Versus Ketorolac as an Adjuvant to Peribulbar Block for Anterior Segment Surgeries
This study aims to compare the efficacy of ketorolac and fentanyl as adjuvants to local anesthetics for anterior segment surgeries of the eye.
- Conditions
- Fentanyl, Ketorolac, Adjuvant, Peribulbar Block
- Trial name
- NCT07141589
- Testing
- Lidocaine + Bupivacaine + Hyaluronidase, Fentanyl + Lidocaine + Bupivacaine + Hyaluronidase, Ketorolac + Lidocaine + Bupivacaine + Hyaluronidase
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- Cairo University
Peribulbar Block
Minimum Effective Volume of Local Anesthetic for Peribulbar Block.Does it Differ With the Eyeball Axial Length?
The aim of this study is to calculate the minimum effective volume of local anesthetic for peribulbar block in patients undergoing cataract extraction surgery.
- Trial name
- NCT04036201
- Testing
- Bupivacaine
- Where
- Egypt
- Volunteers
- 121 people
- Sponsor
- Ain Shams University
Vitreoretinal Surgery
Comparative Study Between Different Additives to Lidocaine 2٪ for Peribulbar Block in Vitreoretinal Surgery
Peribulbar block, is the favored anesthetic technique for numerous ophthalmic procedures due to its lower rate of associated complications .
- Trial name
- NCT07519694
- Testing
- · Group M (Midazolam):, · Group C (Cisatracurium):, Group L (Control)
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Sohag University
Ophthalmic Surgery, Parabulbar Block
Anaesthesia for Ophthalmic Surgery: How "Retro" is the Peribulbar Block?
Ophthalmic surgery on the posterior section of the eye can either be performed under general anaesthesia or under local aneasthesia. The local anaesthesia is performed by injecting local anaesthetics behind the eye.
- Trial name
- NCT01258959
- Testing
- Ultrasound detection of local anesthetics spread
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Sunnybrook Health Sciences Centre
Analgesia
Peribulbar Block Versus Subtenon's Injection in Redo Vitreoretinal Surgery
To compare the efficacy and efficiency of peribulbar block versus sub-Tenon's capsule injection of local anesthetic in redo vitreoretinal surgery
- Trial name
- subtenon's (NCT04978415)
- Testing
- peribulbar block versus subtenon's block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abeer Samir Salem
Retinal and Infra-ocular Pathology
Traditional Blind Versus Ultrasound-guided Peribulbar Blockade
Eye surgeries are traditionally performed under local anaesthesia with a peribulbar block. This is a blind technique where local anaesthetic is injected into the back of the eye to make the eye numb and motionless for surgery.
- Trial name
- NCT02151968
- Testing
- Local Anaesthetic Injection, Ultrasound-Guidance
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Sunnybrook Health Sciences Centre
Hemodynamic Effect, Dexmedetomidine
Hemodynamic Effect of Dexmedetomidine Versus Magnesium Sulphate as an Adjuvant to Lidocaine in Preemptive Peribulbar Block in Patients Undergoing Dacryocystorhinostomy Under General Anesthesia
This study aims to compare the hemodynamic effect of dexmedetomidine and magnesium sulphate as an adjuvant to lidocaine in preemptive peribulbar block in patients undergoing Dacryocystorhinostomy (DCR) under general anaesthesia…
- Conditions
- Hemodynamic Effect, Dexmedetomidine, Magnesium Sulphate, Lidocaine
- Trial name
- NCT07675616
- Testing
- Lidocaine + Dexmedetomidine, Lidocaine + Magnesium sulphate, Lidocaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Anesthetics, Local
Heavy Bupivacaine in Peribulbar Block
Most of the ophthalmic procedures are performed under local anesthesia as the patient is often elderly and with diseases. This may increase the risk of morbidity and mortality under general anesthesia.
- Trial name
- NCT03312959
- Testing
- hyperbaric bupvacaine in Peribulbar block, isobaric bupvacaine in Peribulbar block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Strabismus
Peribulbar Block for Prevention of Oculocardiac Reflex
Strabismus is a common ophthalmic problem in Egypt that usually requires surgical correction. This surgery primarily aims to improve alignment of visual axis but may be required only for cosmetic reasons.
- Trial name
- NCT04549844
- Testing
- Bupivacaine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Fayoum University Hospital
Sedation for Patients Undergoing Peribulbar Block
A Comparative Study of Oral Gabapentin, Oral Alprazolam and Intravenous Dexmedetomidine on Perioperative Anxiety and Pain During Posterior Segment Eye Surgery Under Peribulbar Block : a Randomized, Double-blind Study.
We hypothesized that gabapentin when given orally as a premedication in patients who perform posterior segment eye surgery under peribulbar block would provide adequate anxiolysis and arousable sedation as alprazolam and…
- Trial name
- NCT04658732
- Testing
- Administration of Alprazolam , Gabapentin , Dexmedetomidine
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Ehab Tarek Fahmy
Pain
Fentanyl as an Adjuvant to Peribulbar Block in Buckle or Squint Surgeries
The use of fentanyl as an adjuvant to local anesthetic mixture in many regional blocks. It was effective when used in peribulbar block in cataract and vitreoretinal surgeries.
- Trial name
- NCT05539911
- Testing
- Fentanyl
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Research Institute of Ophthalmology, Egypt
Ophthalmic Artery, Peribulbar Block
Ophthalmic Artery Resistance Index After Peribulbar Block in the Presence of Epinephrine
Evaluate ophthalmic artery flow by echo-Doppler before and after peribulbar block with lidocaine in presence or absence of epinephrine.
- Trial name
- NCT04153123
- Testing
- Epinephrine
- Where
- Brazil
- Volunteers
- 26 people
- Sponsor
- Federal University of Minas Gerais
Anesthesia, Local, Ophthalmopathy
Comparison Between Peribulbar And Sub-tenon Blocks on Oculocardiac Reflex (OCR) During Pediatric Strabismus Surgery
The aim of this study is to compare between peribulbar block and subtenon block as an adjunct to general anesthesia in children undergoing strabismus surgery on oculocardiac reflex (OCR), post-operative analgesia and…
- Conditions
- Anesthesia, Local, Ophthalmopathy, Strabismus, Pediatric ALL
- Trial name
- NCT06293586
- Testing
- peribulbar block, sub-tenon block, Paracetamol
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cairo University