Clinical trials: Pericarditis Acute
Pericarditis, Pericarditis Acute
Phase 2/3 Study of Participants With Recurrent Pericarditis Evaluating the Efficacy and Safety of KPL-387
This study is being done to demonstrate whether KPL-387 is an effective and safe treatment for recurrent pericarditis.
- Conditions
- Pericarditis, Pericarditis Acute, Recurrent Pericarditis
- Trial name
- PASTORALE (NCT07010159)
- Testing
- KPL-387
- Where
- 66 sites in United States, Canada and 8 more
- Volunteers
- 325 people
- Sponsor
- Kiniksa Pharmaceuticals International, plc
Acute Chest Syndrome
ST Elevation in Acute Chest Pain; Could Measurement of Lipoprotein-associated Phospholipase A2 (Lp-PLA2) be Helpful to the Clinician?
A blood test (2-3 cc peripheral venous blood) drawn /used from already available required lab tests to distinguish between pericarditis accompanied with electrocardiogram (ECG) signs mimicking infarction.
- Trial name
- NCT01041339
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexhander Izhaki
Acute Pericarditis, Pericardial Effusion
Pericardial Fluid Analysis in Recurrent Pericarditis
This clinical trial aims to examine the biochemical and cytological features of pericardial effusion during acute and recurrent pericarditis and to understand the molecular factors responsible for pathogenesis.
- Conditions
- Acute Pericarditis, Pericardial Effusion, Pericardial Disease, Pericardial Fluid Exudate
- Trial name
- PEFLANA (NCT06293924)
- Testing
- Pericardiocentesis, Pericardiotomy, Cytofluorometry and Gene expression analysis
- Where
- Italy
- Volunteers
- 432 people
- Sponsor
- ASST Fatebenefratelli Sacco
Acute Pericarditis
Treatment of Acute Pericarditis With Anakinra
The goal of this study is to determine the safety and efficacy of anakinra for the treatment of acute pericarditis when initiated within 6 hours of diagnosis and continued for 3 or 7 days. 1.
- Trial name
- NCT03224585
- Testing
- Anakinra
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Virginia Commonwealth University
Inflammation, Cardiovascular Diseases
Inflammation in Acute Cardiovascular Diseases - the CArdiovascular Inflammation Registry (CAIR)
Following acute cardiovascular injury, inflammation is vital to activate reparative mechanisms. However, there is compelling evidence implicating excessive inflammation and dysregulated resolution in fibrosis, ventricular…
- Conditions
- Inflammation, Cardiovascular Diseases, Myocarditis, Pericarditis
- Trial name
- CAIR (NCT06411340)
- Testing
- Observation
- Volunteers
- 1,000 people
- Sponsor
- King's College London
Pericarditis
Study of Colchicine to Treat Acute Pericarditis and Prevent Recurrences
The purpose of the study is to determine whether colchicine is safe and effective in the treatment of acute pericarditis and the prevention of subsequent recurrences.
- Trial name
- NCT00128453
- Testing
- Colchicine (for 3 months)
- Where
- 4 sites in Italy
- Volunteers
- 240 people
- Sponsor
- Azienda Sanitaria Locale 3, Torino
Acute Coronary Syndrome, Heart Failure
A Survey of Hospitalizations in Cardiology Units in Sub-Saharan Africa
FEVRIER study is an observatory of hospitalizations in cardiology units in sub-Saharan Africa.
- Conditions
- Acute Coronary Syndrome, Heart Failure, Syncope, Stroke
- Trial name
- FEVRIER (NCT03231449)
- Testing
- observation of current care
- Where
- 20 sites in Benin, Burkina Faso and 11 more
- Volunteers
- 5,000 people
- Sponsor
- Cardiologie et Développement
Pericarditis Acute
Dexamethasone Compared to Non-steroidal Anti-inflammatory Drugs in the Treatment of Acute Pericarditis
The treatment of acute pericarditis is empiric and is based on treatment with medications with anti-inflammatory properties such as non-steroidal anti-inflammatory drugs (NSAID) and corticosteroids.
- Trial name
- Dexa-P (NCT04323280)
- Testing
- Dexamethasone therapy, NSAID therapy
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Rabin Medical Center
Pericarditis
Prognostic Biomarkers in Patients With Acute Pericarditis
The study will aim at investigating novel plasma or imaging biomarkers in patients with acute pericarditis. All participants will be treated according to established clinical recommendations for the diagnosis and treatment of…
- Trial name
- NCT02754713
- Where
- Greece
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hippocration General Hospital
Pericarditis
Benign Acute Pericarditis: Brief Versus Longer Treatment Using Aspirin
Treatment of pericarditis largely remains empirical due to the relative lack of randomized controlled trials. Nevertheless, some recommendations have been formulated to guide management and follow-up of acute pericarditis.
- Trial name
- pericardite (NCT00946907)
- Testing
- Aspirin
- Where
- 12 sites in France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Brest
COVID-19 Associated Cardiac Involvement, Remodeling, Left Ventricle
Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19
Long COVID or Postacute sequelae of COVID-19 infection (PASC) are increasingly recognised complications, defined by lingering symptoms, not present prior to the infection, typically persisting for more than 4 weeks.
- Conditions
- COVID-19 Associated Cardiac Involvement, Remodeling, Left Ventricle, Remodeling, Vascular, Left Ventricular Dysfunction
- Trial name
- MYOFLAME-19 (NCT05619653)
- Testing
- Prednisolone, Losartan
- Where
- 5 sites in Austria, Germany
- Volunteers
- 279 people
- Sponsor
- Valentina Puentmann
Myocarditis, Myocarditis Acute
MYocarditis and/or Pericarditis Following mRNA COVID-19 VACCination National Surveillance Study
Myocarditis is inflammation of the heart muscle. Pericarditis is inflammation of the lining surrounding the heart muscle. Symptoms of these conditions can include pain in the chest and rapid or irregular heartbeat.
- Conditions
- Myocarditis, Myocarditis Acute, Pericarditis, Pericarditis Acute
- Trial name
- MYCOVACC (NCT06103123)
- Testing
- Stand of care ECG, Holter, MRI, ECHO, Quality of life questionnaire, Baseline Quality of Life questionnaire
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Cardiology Research UBC