Clinical trials: Periimplant Bone Loss
Periimplant Crestal Bone Level Changes
Influence of Platform-switching on Bone Level Alterations: a 3 Year Randomized Clinical Trial (RCT).
The concept of platform-switching has been introduced to implant dentistry based on clinical observations of reduced periimplant crestal bone loss.
- Trial name
- NCT01917305
- Testing
- platform-shifted implant
- Volunteers
- 25 people
- Sponsor
- Søren Jepsen
Implant Complication, Periimplant Infection
The Effect Of Photobiomodulation On Dental Implant Survival
Dental implants offer a high success rate as the most up-to-date treatment method for replacing lost teeth. However, whilst implants have emerged as the ideal treatment for tooth loss, the incidence of postoperative…
- Conditions
- Implant Complication, Periimplant Infection, Periimplant Bone Loss
- Trial name
- NCT07636265
- Testing
- photobiomodulation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Alveolar Bone Loss, Dental Implant
Evaluation of the Effect of Periimplant Soft Tissue Phenotype on Marginal Bone Loss
The goal of this clinical trial to test the effect of periimplant soft tissue phenotype in the participants with implant placed and at least 1 year after implant loading. The main questions it aims to answer are: 1.
- Conditions
- Alveolar Bone Loss, Dental Implant, Periimplantitis
- Trial name
- NCT05640284
- Testing
- Nuclear Factor-Kappa B Ligand (RANKL) analysis, Osteoprotegerin (OPG) analysis, Tumor Necrosis Factor Alpha (TNF-α) analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people
- Sponsor
- Necmettin Erbakan University
Complete Edentulism
PeriImplant Soft Tissue and Marginal Bone Loss of Single Implant Mandibular Overdenture
There is a significant difference between CM LOC and ball attachment, when considering the peri-implant soft tissue health and marginal bone loss.
- Trial name
- NCT02881905
- Testing
- ball attachment, cm loc attachment
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss, Partially Edentulous Jaw
Impact of Hyaluronic Acid and Bone Graft on Peri-Implant Tissue
This randomized controlled clinical trial aims to evaluate the effect of hyaluronic acid (HA) and particulate bone graft on the peri-implant tissue phenotype in patients receiving dental implants.
- Conditions
- Alveolar Bone Loss, Partially Edentulous Jaw, Dental Implant
- Trial name
- NCT07665281
- Testing
- Dental Implants with Hyaluronic Acid, Dental Implants with Hyaluronic Acid and Particulate Bone Graft, Standard Dental Implants Placement only
- Where
- 2 sites in Iraq
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Edentulism, Dental Implantation, Endosseous
Subcrestal vs Juxtacrestal PRAMA Implants With Variable Necks
The goal of this clinical trial is to understand how different implant neck designs and placement depths affect the surrounding bone and peri-implant tissue (the tissue around a dental implant) in adults who need implants in the…
- Conditions
- Edentulism, Dental Implantation, Endosseous, Marginal Bone Loss, Periimplant Bone Loss
- Trial name
- NCT07107464
- Testing
- Short Neck Implant - Crestal Placement, Standard Neck Implant - 1 mm Subcrestal Placement, Long Neck Implant - 2 mm Subcrestal Placement
- Where
- Cuba
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy
Peri-implant Bone Loss, Peri-implant Marginal Bone Loss
Evaluation of Fluid Biomarkers Around Implants Exhibiting Early Stage Periimplant Bone Loss
This study aimed to compare biological mediators known to be important in peri-implant diseases in implants with and without early stage marginal bone loss.
- Conditions
- Peri-implant Bone Loss, Peri-implant Marginal Bone Loss, Marginal Bone Loss, Peri-Implant Health
- Trial name
- NCT07584759
- Testing
- Collecting of peri-implant sulcus fluid, Periapical radiography
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Periimplant Bone Loss, Marginal Periimplant Bone Level
Changes on the Interproximal Bone Level on Direct Prostheses or With Intermediate Abutments
Study Title: Changes on the Interproximal marginal bone level after CAD-CAM designed bridges directly placed on bone-level implants, or with intermediate abutments. A Randomized Clinical Trial.
- Conditions
- Periimplant Bone Loss, Marginal Periimplant Bone Level, Periimplantitis
- Trial name
- NCT04369170
- Testing
- prosthesis connected directly to the implants, Intermediate abutment
- Where
- Spain
- Volunteers
- 37 people
- Sponsor
- University of Santiago de Compostela
Peri-Implantitis and Peri-implant Mucositis, Peri-implant Mucositis
Salivary Minerals in Patients With Peri-implantitis
Patients included in the study will be recruited after arriving at the Faculty of Dentistry of the University of Zagreb. During the clinical examination, the patient's periodontal status (bleeding during probing, and the depth of…
- Conditions
- Peri-Implantitis and Peri-implant Mucositis, Peri-implant Mucositis, Periimplant Bone Loss, Periimplant Diseases
- Trial name
- mineral-perio (NCT05897736)
- Volunteers
- 25 people
- Sponsor
- University of Zagreb
Periodontal Diseases, Periimplant Diseases
Markers of Bone Destruction and Oxidative Stress in Peri-implantitis
The aim of this study is to evaluate and compare the levels of bone resorption (RANKL, OPG) and oxidative stress (Nitrotyrosine, NQO1) markers, along with pro-inflammatory cytokines (IL-1β), in the saliva and peri-implant…
- Trial name
- NCT07397884
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Horizontal Alveolar Bone Defect, Alveolar Bone Loss
Evaluation of Mineralized Plasmatic Matrix With and Without Collagen Membrane in Peri-implant Bone Regeneration
This study focuses on comparing the effect of MPM with or without collagen membrane on delayed implant placement in anterior maxillary aesthetic zone.
- Trial name
- NCT04816110
- Testing
- mineralized plasmatic matrix with collagen membrane, mineralized plasmatic matrix (MPM) without collagen membrane
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Alexandria University
Peri-implant Marginal Bone Loss, Peri-implant Bone Level
Influence of the Design of the Transmucosal Abutment on the Periimplant Bone Level
The objective of this study is to evaluate the radiographic changes on the marginal peri-implant bone level on bone level implants with a narrower transmucosal abutment, in comparison to the conventional abutment, both of 3mm…
- Conditions
- Peri-implant Marginal Bone Loss, Peri-implant Bone Level, Transmucosal Abutment Design, Peri-implant Bone Loss
- Trial name
- NCT04385355
- Testing
- Conventional transmucosal abutment design, Narrow transmucosal abutment design
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- University of Santiago de Compostela
Teeth Absent, Tooth-loss
Peri-implant Tissues on the Galimplant Anti-rotational Slim Abutment.
A dental implant is an alloplastic material surgically inserted in a residual bone ridge, mainly with a prosthetic foundation. Nowadays the most widely used implants and with a higher degree of scientific evidence are the…
- Conditions
- Teeth Absent, Tooth-loss, Tooth Extraction, Dental Implant
- Trial name
- NCT05118815
- Testing
- Slim abutment, Standard abutment
- Where
- Spain
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Periimplantitis
Application of Local Melatonin in Peri-implantitis
A randomized clinical trial was carried out in patients affected by peri-implantitis with a follow-up of 60 days. Melatonin 1.9 mg or placebo was applied locally to the peri-implant defect after nonsurgical debridement.
- Trial name
- MEL19 (NCT06816277)
- Testing
- Desbridamiento de periimplantitis, Aplicación de melatonina
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid