Clinical trials: Perimenopausal Women
Quality of Life, Depression
Effects of Jin Shin Jyutsu-Based Hand Application on Quality of Life and Psychosocial Status in Perimenopausal Women
This study aims to evaluate the effect of Jin Shin Jyutsu-based hand application guided by the Transactional Model of Stress and Coping on quality of life and psychosocial status in perimenopausal women.
- Conditions
- Quality of Life, Depression, Anxiety, Stress
- Trial name
- NCT07376395
- Testing
- General Health Education, Jin Shin Jyutsu®-Based Hand Application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Mental Health, Perimenopause
Impact of Intermittent Fasting on the Mental Health of Perimenopausal Women
This study will explore how intermittent fasting (specifically the 16/8 method) affects the mental health of women who are in the perimenopause stage.
- Conditions
- Mental Health, Perimenopause, Intermittent Fasting
- Trial name
- NCT07481513
- Testing
- Intermittent fasting (16/8)
- Where
- Lebanon
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Menopausal Women
The Effect of Value Clarification Based on Meleis's Transition Theory on Menopausal Symptoms, Depression, Anxiety, Stress, and Quality of Life in Perimenopausal Women
Menopause is a life stage influenced not only by hormonal factors but also by psychological, social, and cultural factors. Symptoms such as hot flashes, sleep problems, and mood changes may occur, and their severity depends on…
- Trial name
- NCT07584109
- Testing
- value clarification, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ordu University
Sarcopenia, Physical Inactivity
Women in Action: A Multicomponent Intervention for Older Women
"Women in Action" is a quasi-experimental, mixed-methods study evaluating a 16-week multicomponent intervention (supervised strength/aerobic/balance training plus psychoeducational and nutrition-focused behavioral workshops) for…
- Conditions
- Sarcopenia, Physical Inactivity, Menopause, Healthy Aging
- Trial name
- WIA (NCT07860424)
- Testing
- Multicomponent exercise, nutrition, and psychoeducational program
- Where
- 2 sites in Spain
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Universidad de Oviedo
Perimenopausal Bone Loss
Prunes Preventing Bone Loss in Perimenopause
Dietary interventions of prune consumption during the transmenopausal period are innovative methods to prevent bone loss. Modern medicine does not intervene to prevent or attenuate this highly vulnerable period of bone loss…
- Trial name
- Prune-UP (NCT07120997)
- Testing
- Prunes, Calcium supplement, Vitamin D Supplement
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Penn State University
Perimenopausal Women, Postmenopausal Female Patients
Female-Specific Modifiers for Healthy Early Action in Cardiovascular Risk Trajectories
Cardiovascular disease is the leading cause of death in women, yet risk is systematically underestimated and preventive interventions are often initiated too late.
- Conditions
- Perimenopausal Women, Postmenopausal Female Patients, Cardiovascular (CV) Risk
- Trial name
- FEM-HEART (NCT07703124)
- Testing
- Personal training, App-based physical intervention
- Volunteers
- 605 people, healthy volunteers welcome
- Sponsor
- Ludwig Boltzmann Institute for Cardiovascular Research
Perimenopausal Women, Body Composition Changes
Nutritional Supplementation on Physiological and Metabolic Markers in Females
The goal of this clinical trial is to learn if a 12-week nutritional supplement can result in significant changes in the body composition of 38-55-year-old females.
- Trial name
- NCT07615777
- Testing
- Nutritional Supplement
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Menopause
A Nutritional Supplement on Vasomotor Symptoms in Women
Vasomotor symptoms (VMS), such as flushes, sweating, and sleep disturbances, are experienced by up to 80% of women during the menopausal transition.
- Trial name
- NCT04516304
- Testing
- S-equol
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Pharmavite LLC
Serum CNP Levels, Healthy Reproductive Age Women
Serum Levels of C Type Natriuretic Peptide in Different Reproductive Periods
Recent studies have shown that C natriuretic peptide (CNP) is produced from granulosa cells, increasing cumulative guanosine monophosphate (cGMP) production by affecting cumulus cells through natriuretic peptide receptors.It has…
- Conditions
- Serum CNP Levels, Healthy Reproductive Age Women, Healthy Perimenopausal Women, Healthy Postmenopausal Women
- Trial name
- CO (NCT04000815)
- Testing
- C Type Natriüretic Peptide
- Where
- Cyprus
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Climacteric Syndrome, Postmenopausal Symptoms
Multimodal Program for Climacteric Women
Your study seems to aim at emphasizing the significance of non-pharmacological and non-hormonal approaches in managing menopausal symptoms, particularly focusing on muscle training and education.
- Conditions
- Climacteric Syndrome, Postmenopausal Symptoms, Menopause, Perimenopausal Disorder
- Trial name
- NCT06419972
- Testing
- multimodal physiotherapy programme
- Where
- 2 sites in Spain
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Bone Health in Perimenopausal Women
A 12-week Human Trial to Compare the Efficacy and Safety of Polycan on Bone Metabolism
Beta-glucans are polysaccharides consisting of glucose residue jointed by beta linkage. They are found at a high level in the cell wall of fungi, yeast, oat, barley, bacteria, as well as various mushroom.
- Trial name
- NCT01402115
- Testing
- Polycan
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Perimenopause, Climacteric Syndrome
Clinical Evaluation of Effectiveness and Safety of Amberen and Smart B in Perimenopausal Women.
To evaluate effectiveness and safety of combined use of dietary supplements Amberen and Smart B in women with a typical (without complications) form of climacteric syndrome, with mild to moderate symptoms in perimenopause.
- Trial name
- NCT03897738
- Testing
- Amberen, Smart B
- Where
- Russia
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Post-menopause, Pre-menopause
VEDA Study (DHEA vs Estradiol)
This study is being done to compare two vaginal treatments, vaginal estrogen and vaginal DHEA, that are used to treat vaginal and urinary symptoms related to menopause.
- Conditions
- Post-menopause, Pre-menopause, Sexual Function, Menopause
- Trial name
- NCT07574216
- Testing
- DHEA ovals, Estradiol 0.01% Vag Cream
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Perimenopausal Bone Loss
Natto Supplementation to Prevent Loss of Bone Mass in Women Immediately After Menopause
Study Objective: To determine whether Natto supplementation in women immediately after menopause might prevent severe bone loss Study population: Women 50 - 60 years, 1-5 years after menopause Study Design: Double-blind…
- Trial name
- NCT00290212
- Testing
- Natto capsules (food suppl.) cont. 360 microg. vit K2/day
- Where
- 2 sites in Norway
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Menopausal Syndrome, Atherosclerosis
Study of Anti-atherosclerotic and Estrogen-like Activity of Karinat in Perimenopausal Women
The purpose of this study is to investigate the anti-atherosclerotic and anti-climacteric action of natural drug Karinat based on phytoestrogen-rich botanicals in perimenopausal women.
- Trial name
- PEARS (NCT01741974)
- Testing
- Karinat
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Institute for Atherosclerosis Research, Russia
Low Ovarian Reserve, Poor Responders to Gonadotropihins Treatment
Can Dormant Perimenopausal Ovarian Follicles Become FSH Responsive?
The purpose of this study to obtain ovarian cortical fragments from perimenopausal patients, who undergo pelvic organ surgery and test whether treatment with PTEN inhibitor and PI3K activating peptide would induce these fragments…
- Trial name
- NCT01201226
- Testing
- Removal of half an ovary
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Menopause
DBPCT Effects of Omega-3 FA on Memory and Cognition in Peri- and Menopausal Women
The goal of this clinical trial is to learn if daily omega-3 supplementation improves memory and cognitive function in perimenopausal and menopausal women aged 40-60 years.
- Trial name
- NCT07814300
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Arthralgia, Menopause
The MUSE Study for Menopausal Arthralgia
The investigators plan to conduct a pilot 4-arm, randomized study comprising the following interventions: muscle strengthening exercises (MSE) alone, estrogen therapy (ET) alone, and a combination of MSE and ET, compared to usual…
- Conditions
- Arthralgia, Menopause, Perimenopausal Disorder, Joint Pain
- Trial name
- MUSE (NCT06530459)
- Testing
- Menopausal hormone therapy, Exercise training, Menopausal hormone therapy + exercise training
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Apparently Healthy and Not Receiving Hormonal Therapy
Examining the Impact of Phytoestrogens Supplementation on the Gene Expression, and Premenstrual Syndrome in Primenopausal Women
This randomized, double-blind, placebo-controlled clinical trial investigated the effects of flaxseed-derived phytoestrogen supplementation on selected gene-expression markers and premenstrual syndrome (PMS) severity among…
- Trial name
- NCT07310485
- Testing
- SDG lignans
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Sleep Initiation and Maintenance Disorders, Depression
Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia
This study will evaluate the effectiveness of estrogen replacement therapy in treating depression in menopausal women with hot flashes and insomnia.
- Trial name
- NCT00227942
- Testing
- Estrogen Replacement Therapy, Zolpidem
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Hadine Joffe, MD