Clinical trials: Perinatal, open to volunteers
Gestational Diabetes Mellitus, Postpartum Depression
Gestational Diabetes and Perinatal Depression: an Intervention Program
Background: The gestational diabetes mellitus and perinatal depression are both global public health issues with high prevalence.
- Conditions
- Gestational Diabetes Mellitus, Postpartum Depression, Perinatal Depression
- Trial name
- NCT05800509
- Testing
- Clips Intervention, Structured Questionnaire Only
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Perinatal Anxiety, Anxiety Sensitivity
Reaching Calm: A Digital Intervention to Prevent Perinatal Anxiety Disorders
The goal of this clinical trial is to find out if a digital program called Reaching Calm can help prevent anxiety in women who are pregnant.
- Conditions
- Perinatal Anxiety, Anxiety Sensitivity, Perinatal Depression
- Trial name
- NCT07458698
- Testing
- Digital mental health intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Massachusetts, Worcester
Postpartum Depression (PPD), Postpartum Anxiety
mHealth Intervention to Prevent Postpartum Depression and Anxiety in Chilean Women (WWWT)
The goal of this clinical trial is to evaluate the effectiveness of a digital psychoeducational intervention, "What Were We Thinking" (WWWT), to prevent the development of postpartum depression and anxiety symptoms in first-time…
- Trial name
- NCT07587177
- Testing
- What Were We Thinking (WWWT) mHealth Intervention
- Volunteers
- 220 people
- Sponsor
- Universidad del Desarrollo
Gestational Diabetes
Maternal Sleep and Lifestyle, Metabolic Health, and Perinatal Outcomes in Gestational Diabetes
The goal of this observational study is to learn how sleep quality, mental health, lifestyle behaviors, and metabolic markers are related to glucose control and pregnancy outcomes in women with gestational diabetes mellitus…
- Trial name
- NCT07314944
- Testing
- Home-Based Glucose Monitoring, Inpatient Glucose Monitoring
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- University of Split, School of Medicine
Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy
Nephroprotection Following Perinatal Asphyxia: Randomized Controlled Trial
The aim of this study is to determine the value of Pentoxifylline for nephroprotection in these neonates with perinatal asphyxia, using cystatin C, regional oxygenation measured near infrared spectroscopy and renal Doppler…
- Conditions
- Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy, Pentoxifylline Adverse Reaction
- Trial name
- NCT07088328
- Testing
- Pentoxifylline
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Death; Neonatal, Morbidity;Newborn
The TELENEO Trial: A Multicenter Trial of Telemedicine for Advanced Neonatal Resuscitations in Community Hospitals
The purpose of this study is to evaluate the impact of real-time audio-video telemedicine consults with a neonatologist (termed teleneonatology) on the early health outcomes of at-risk neonates delivered in community hospitals.
- Trial name
- NCT06087224
- Testing
- Teleneonatology
- Where
- 36 sites in United States, Canada
- Volunteers
- 947 people
- Sponsor
- Mayo Clinic
Mother to Child Transmission, Breast Feeding
Trauma-informed Obstetric Care for Perinatal Health: a Pilot Study
The study will test trauma-informed obstetric care training and supervision for obstetric clinicians in relation to prenatal mental health and attachment formation (early predictors of child development) in women presenting for…
- Conditions
- Mother to Child Transmission, Breast Feeding, Trauma
- Trial name
- NCT07195058
- Testing
- Trauma Informed Obstetric Care (TIOC)
- Where
- Argentina
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Columbia University
Perinatal Depression, PerinatalAnxiety
Perinatal Depression & Anxiety (PDA) and Maternal Gut Microbiome
Perinatal depression and anxiety (PDA) are the leading causes of maternal mortality in developed countries. Women with a history of depression have a 20 fold higher risk of PDA at subsequent pregnancies.
- Trial name
- NCT06074250
- Testing
- Fish oil, Probiotics, Prebiotics
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- The Canadian College of Naturopathic Medicine
Perinatal Loss, Perinatal Grief
The Effect of Nursing Care With Peri-Natal Loss
This study was planned to evaluate the effect of standardised nursing care given to women with perinatal loss using the nursing process on perinatal grief, posttraumatic stress and postpartum depression.
- Trial name
- NCT06896214
- Testing
- Standardised nursing care intervention
- Volunteers
- 58 people
- Sponsor
- Gazi University
Maternal Care
Holistic Care Partner Program Feasibility and Acceptability
The study aims to build on the knowledge of the United States' ongoing maternal health crisis for Black birthing people. The study team will take a holistic focused approach to build on the experiences of Black women perinatal…
- Trial name
- NCT06520566
- Testing
- Holistic care partner perinatal nurse navigation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
RSV Infection
Real-World Effectiveness of Perinatal RSV Immunoprophylaxis
The purpose of this study is to continue evaluating how well the RSV vaccines work as they are currently being used in routine clinical practice.
- Trial name
- NCT06172660
- Testing
- Nirsevimab
- Where
- United States
- Volunteers
- 3,750 people
- Sponsor
- Yale University
Anxiety in Pregnancy, Mood Disorder Due to Specified Medical Condition
Preventing Maternal Mood, Anxiety, and Trauma Symptoms After Cesarean Delivery
Perinatal mental health disorders are the most prevalent perinatal comorbidity and are associated with the primary cause of maternal mortality in the United States (US) - suicide.
- Trial name
- NCT06949813
- Testing
- BE-OR: Brief Intervention to the Operating Room, Interaction: Facetime with Clinical Provider
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Colorado, Denver
Perinatal Depression
Clinical and Cost-effectiveness of an Online Self-help Intervention and a Face-to-face Intervention Versus Usual Care in Mothers at Moderate Risk for Perinatal Depression
The perinatal period (pregnancy and the first postnatal year) (O'Hara \& Wisner, 2014) involves important changes and considerable challenges for parents (Milgrom \& Gemmill, 2015).
- Trial name
- MaMHI (NCT07027761)
- Testing
- Online self-help, Maternal Mental Health Intervention (MaMHI), Usual Care
- Where
- Belgium
- Volunteers
- 210 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Postpartum Contraception
Effect of Joint Provision of Community Group-based Counseling with Individual Counseling on Postpartum Contraception
The aim of this trial is to assess the effectiveness of joint provision of community group-based demonstration counseling methods with routine individual family planning counseling provided to prenatal and postnatal women on…
- Trial name
- NCT06766409
- Testing
- A community group-based demonstration counseling method, An individual family planning counseling
- Where
- Ethiopia
- Volunteers
- 598 people, healthy volunteers welcome
- Sponsor
- St. Paul's Hospital Millennium Medical College, Ethiopia
Posttraumatic Stress Disorder (PTSD), Pregnancy
Cognitive Processing Therapy (CPT) for Perinatal Posttraumatic Stress Disorder (PTSD)
Pregnant women with a primary diagnosis of posttraumatic stress disorder (PTSD) (PTSD Checklist for DSM-5 (PCL-5) score > 33) will be randomized to receive conventional cognitive processing therapy (CPT) (60-min session once/week…
- Trial name
- NCT07060144
- Testing
- Regular CPT, Massed CPT
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Texas at Austin
Hypoxic Ischemic Encephalopathy of Newborn, Hypoxic Ischemic Encephalopathy
The HIEnome Study: Genome Sequencing for Perinatal HIE
Perinatal hypoxic-ischemic encephalopathy is a rare severe condition in which neonates present with encephalopathy and a clinical history suggestive of prenatal or perinatal hypoxic-ischemic injury.
- Conditions
- Hypoxic Ischemic Encephalopathy of Newborn, Hypoxic Ischemic Encephalopathy, Hypoxic Ischemic Encephalopathy (HIE)
- Trial name
- NCT06762795
- Testing
- Genome sequencing
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Baylor College of Medicine
Depression, Anxiety, Antenatal Depression
Integration of Stepped Care for Perinatal Mood and Anxiety Disorders Among Women Attending MCH Clinics
Perinatal mood and anxiety disorders (PMAD), defined as depression and anxiety during pregnancy or up to 1 year postpartum, account for substantial morbidity and mortality among birthing people globally especially in low- and…
- Conditions
- Depression, Anxiety, Antenatal Depression, Postnatal Depression
- Trial name
- IPMH (NCT06456307)
- Testing
- Integrated Perinatal Mental health program (systematic screening for PMAD, PM+ and tele-psychiatry)
- Where
- 2 sites in Kenya
- Volunteers
- 2,970 people, healthy volunteers welcome
- Sponsor
- Kenyatta National Hospital
Premature Infant, Risk Factors
Perinatal Risk Factors in Motor Development
The aim of this study is to analyze the effect of preterm gestational age, birth weight and perinatal risks factors on gross motor development of preterm infants.
- Conditions
- Premature Infant, Risk Factors, Motor Development of Premature Infants
- Trial name
- NCT07310459
- Where
- Spain
- Volunteers
- 160 people
- Sponsor
- Universidad de Murcia
Intimate Partner Violence
Assessment of Healthcare Professionals' Preparedness to Screen for and Manage Women Experiencing Intimate Partner Violence During the Perinatal Period
AP-HP has recently opened five hospital-based care units dedicated to supporting women who are victims of violence. Referrals of women to these units rely mainly on healthcare professionals.
- Trial name
- PREMIS-PERINAT (NCT07818096)
- Testing
- PREMIS Questionnaire
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mental Health Screening Adherence
Evaluating Screening Adherence Between Moment for Parents App and Attention Control
Mental health challenges, such as depression and anxiety, are the most common medical complications during pregnancy and after childbirth. Many women experience these symptoms, yet half are never screened, let alone diagnosed.
- Trial name
- NCT07322042
- Testing
- Perinatal Psychoeducation Articles, Bi-weekly Perinatal Mental Health Screening, Chatbot-Guided Journaling
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Poisera, Inc.