Clinical trials: Perineal Pain
Pelvic Pain
Efficacy of the Photobiomodulation on the Pelvi-perineal Pain in Immediate Post-partum Situation
Photobiomodulation (PBM), evaluated in this study, will be delivered by a CE marked class IIa medical device (MILTA technology), composed of a panel that gathers 18 emitters.
- Trial name
- NCT04896034
- Testing
- MILTA Device, " control 1 " fake MILTA device
- Where
- France
- Volunteers
- 480 people
- Sponsor
- Elsan
Endometriosis, Chronic Pain
Endocare for Pelvic-perineal Pain Related to Endometriosis Used at Home
Women with endometriosis experience recurrent pelvic-perineal pain impairing the quality of life, among other things. Endometriosis-related pain negatively impacts the sexual, family and work life.
- Conditions
- Endometriosis, Chronic Pain, Pelvic Pain
- Trial name
- NCT05172492
- Testing
- Endocare, Digital control
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Lucine
Perineal Pain
Comparison Between Virtual Reality and Stress Ball Intervention In Managing Pain During Episiotomy Repair
This study is a four-arm randomized controlled trial designed to evaluate the effectiveness of non-pharmacological interventions for pain management during episiotomy repair among women undergoing vaginal birth.
- Trial name
- NCT07499011
- Testing
- virtual reality, stress ball, Virtual Reality Plus Stress Ball
- Where
- Iraq
- Volunteers
- 112 people
- Sponsor
- University of Baghdad
Pudendal Neuralgia Pudendal Nerve Entrapment Chronic Pelvic Pain
Pudendal Nerve Block With Articaine and Triamcinolone for Pudendal Neuralgia
This study is testing whether an injection of local anesthetic (articaine) combined with a steroid (triamcinolone), placed near the pudendal nerve under ultrasound guidance, can reduce pain in people with pudendal neuralgia - a…
- Trial name
- NCT07828574
- Testing
- Articaine and triamcinolone
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Irkutsk State Medical University
Episiotomy Wound
Comparison Between Lidocaine Prilocaine Cream and Lidocaine Injection on Pain Control During Episiotomy.
The present study aims to compare the effects of lidocaine-prilocaine cream and lidocaine injection on the reduction of pain while doing and repairing episiotomy, controlling the pain in the post-partum period, and reduction the…
- Trial name
- NCT05891132
- Testing
- 10 ml of lidocaine 2%, lidocaine prilocaine cream 15gm
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vulvodynia, Perineal Pain
Effect of Spinal Manipulation on Vulvar Pain
The purpose of the study is to determine the effect of thoracic spine manipulation on vestibule pain as determined by sensory testing (q-tip and pressure algometry) in a group of women with provoked vestibulodynia (PVD).
- Conditions
- Vulvodynia, Perineal Pain, Vulvar Pain
- Trial name
- SpManipPP (NCT04016467)
- Testing
- Thoracic manipulation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Mary Hardin-Baylor
Perineal Injury, Pain Vulva
Improving Postoperative Recovery: A Study of Multimodal Perineal Analgesia Protocol (MPAP) After Vaginal Surgery
The purpose of this research is to determine if using perineal ice packs, medicated witch-hazel pads (MAJOR® Medi-Pads), and topical benzocaine spray (Dermoplast®) helps reduce perineal pain after perineorrhaphy and/or posterior…
- Conditions
- Perineal Injury, Pain Vulva, Perineum; Injury
- Trial name
- NCT07401134
- Testing
- Perineal ice packs, medicated witch-hazel pads, and topical benzocaine spray
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Miami
Vaginal Delivery, Perineal Swelling
Cold Magnesium Sulfate Solution for Perineal Swelling Following Vaginal Delivery
The purpose of this study is to compare the impact of treatment with cooled magnesium sulfate and cold water-soaked pads on perineal pain and swelling following vaginal delivery.
- Conditions
- Vaginal Delivery, Perineal Swelling, Perineal Pain
- Trial name
- MgSo4 (NCT02024256)
- Testing
- Cold pads soaked in Magnesium sulfate solution, Cold pads soaked in water
- Where
- 2 sites in Israel
- Volunteers
- 206 people
- Sponsor
- HaEmek Medical Center, Israel
Dyspareunia
Trans-perineal Trigger Point Dry Needling for Chronic Pelvic Pain
Chronic Pelvic Pain (CPP) are around 10% of gynaecology referrals.Non-relaxing pelvic floor dysfunction (NRPFD) is an under-appreciated cause for CPP with dyspareunia where no other pathology exists.
- Trial name
- NCT02795026
- Testing
- Manual therapy, Trigger point dry needling
- Where
- 2 sites in Ireland
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Cork University Hospital
Perineal Pain
Efficacy of Ultrasound-assisted Caudal Epidural Pulsed Radiofrequency for Anal Pain in Cancer Patients,
Our primary goal will be to investigate the analgesic efficacy of ultrasound (US)-assisted caudal epidural PRF (pulsed radiofrequency)( stimulation in patients with perineal or anal pain cancer patients using (visual analog scale…
- Trial name
- NCT06008899
- Testing
- US assisted caudal epidural pulsed radiofrequency
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Episiotomy, Platelet Rich Plasma (PRP)
Platelet-Rich Plasma Versus Standard Care for Episiotomy Wound Healing in Postpartum Women
This study looks at whether a treatment made from a patient's own blood, called platelet-rich plasma (PRP), can help heal the cut made during childbirth (episiotomy) better than standard care alone.
- Conditions
- Episiotomy, Platelet Rich Plasma (PRP), Wound Healing, Obstetric
- Trial name
- PRP-EpiHeal (NCT07669285)
- Testing
- Autologous Platelet-Rich Plasma (PRP), Standard Wound Care
- Where
- Romania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Saint Andrew Hospital Constanta
Dermatitis, Radiation Induced
Retrospective Analysis of the Efficacy of Morphine Gel to Treat Pain Associated With Perineal RadioDermatitis
Retrospective study evaluating the efficacy of a pharmacy-prepared Morphine gel used in clinics for the treatment of pain associated with perineal radiodermatitis.
- Trial name
- ANTAGEL (NCT07207889)
- Testing
- morphine chlorhydrate in intrasite gel
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Institut Curie
Perineal Laceration Repair
Comparison of Absorbable Sutures in Perineal Laceration Repair
The purpose of this study is to determine the difference in pain scales between absorbable suture types for second-degree perineal laceration repair.
- Trial name
- NCT00223119
- Testing
- Absorbable Sutures
- Where
- United States
- Sponsor
- Medtronic - MITG
Cervical Cancer, Endometrial Cancer
Hypogastric Plexus Block and Ganglion Impar Block for Cervical and Endometrial Cancer Pain Management
This study compared the efficacy and safety of superior hypogastric plexus block and ganglion impar block procedures on the management of pelvic and perineal cancer pain in patients with cervical and endometrial cancer
- Trial name
- NCT05427058
- Testing
- Superior Hypogastric Plexus Block, Ganglion Impar Block
- Where
- Indonesia
- Volunteers
- 36 people
- Sponsor
- University of Brawijaya
Pain
Continuous Versus Interrupted Sutures for Repair of Episiotomy or Second Degree Tears: a Randomised Controlled Trial
The best technique for this repair would be that which requires least time in realisation, least consumption of material for the repair and that which produces less pain at short and long-term permitting the resumption of…
- Trial name
- NCT00777270
- Testing
- repair of episiotomy or second degree tears
- Where
- Spain
- Volunteers
- 445 people
- Sponsor
- Hospital Universitario Principe de Asturias
Analgesia
Pulsed Radiofrequency of S2-4 Versus Ganglion Impar Neurolysis for Severe Perianal and Perineal Pain in Cancer Patients
Perineal pain resulting from malignancy is usually severe. Pain can be related to the malignancy or as a complication related to the treatment.
- Trial name
- NCT05591430
- Testing
- Ganglion Impar Neurolysis, Bilateral S2, S3 and S4 Pulsed radiofrequency
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- National Cancer Institute, Egypt
Pregnancy, Vaginal Delivery
The Impact of an Epidural Ropivacaine-Neostigmine Injection for Perineal Analgesia at the End of Labor.
Perineal pain after childbirth occurs in the majority of women (with or without episiotomy). Perineal pain can become source of chronic pain in 9%-12% of the cases.
- Trial name
- NCT00407290
- Testing
- neostigmine
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Pelvic Pain Syndrome, Groin Pain
Pelvic Pain Treated With MR-guided Cryoanalgesia
Pelvic pain syndromes have a high prevalence of up to 8% in the general population and up to 50% following pelvic trauma and pelvic surgery.
- Conditions
- Pelvic Pain Syndrome, Groin Pain, Meralgia Paresthetica, Low Back Pain
- Trial name
- NCT04046406
- Testing
- MR neurography-guided cryoanalgesia
- Where
- United States
- Sponsor
- Johns Hopkins University
Pelvic Pain
Comparison of the Effectiveness of Classical Perineal Massage Therapy Versus the Use of an Intravaginal Device to Reduce Postpartum Perineal Pain
GA34.01 postpartum, a randomized design with a parallel group structure will be applied, randomly assigning participants into two groups.
- Trial name
- NCT06921174
- Testing
- Use of the "Crescendo 2" Intravaginal Device, Classical Perineal Massage Therapy
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Instituto Sexológico Murciano
Labor
Instrumental and Non-Instrumental Perineal Message and Childbirth
Today, the increase in the costs of applications in the health care system makes it difficult for easy and inexpensive methods to be used based on evidence.
- Trial name
- NCT05190913
- Testing
- Instrumental perineal massage, manual perineal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University