Clinical trials: Perineum; Rupture
Obstetric Complications, Muscle Tear
Obstetric and Proctology Support of Patients With Perineums Suits
Perineal tear grade III and IV are relatively common (1-10% of deliveries depending on the series), and are a source of potentially serious complications, even long time after delivery (especially disorders of anal continence…
- Trial name
- NCT02823717
- Where
- France
- Volunteers
- 186 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Perineal Tear, Pain
The Application of Honey on Perineal Sutures
Evaluate the effect of honey on perineal tears or episiotomies pain associated or not with anterior vulvar tears after vaginal delivery.
- Conditions
- Perineal Tear, Pain, Burns
- Trial name
- NCT03670420
- Testing
- Medical honey
- Where
- Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Perineal Tear
Hands on vs Hands Off for Perineal Laceration
Perineal trauma at the time of vaginal delivery is common, and when the anal sphincter is included, these injuries can be associated with additional morbidity including incontinence, pelvic pain and sexual dysfunction.
- Trial name
- NCT04860102
- Testing
- hands on
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Federico II University
Dyspareunia, Perineal Tear
Rapidly Absorbing Polyglactin 910 Versus Poliglecaprone 25 for Laceration Repair
To evaluate the rates of dyspareunia with rapidly absorbing polyglactin 910 compared to poliglecaprone 25 using a validated sexual function questionnaire.
- Conditions
- Dyspareunia, Perineal Tear, Sutured Laceration
- Trial name
- NCT03184077
- Testing
- Laceration Repair with Polyglactin 910, Laceration Repair with poliglecaprone 25
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Perineal Tear, Episiotomy Wound
Selective Use of Episiotomy: the Impact on Perineal Trauma.
Vaginal delivery is commonly accompanied by trauma of the genital tract. Perineal trauma is classified into four degrees based on anatomic structures involved and severity of lacerations according to the American College of…
- Conditions
- Perineal Tear, Episiotomy Wound, Delivery; Injury, Maternal
- Trial name
- SEPT-1 (NCT03559816)
- Testing
- Classification of perineal tears based on new classification, Selective use of Episiotomy
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- Universita di Verona
Obstetric Perineal Rupture
Diagnosing Perineal Tears, Does Different Assessment Methods Affect the Midwife's Clinical Judgement of Perineal Tears?
This study aims to compare different midwife practitioners assessments of perineal tears.
- Trial name
- NCT01278979
- Testing
- Objective measurements of perineal tears with "Peri-Rule", Visual and digital assessment
- Where
- Norway
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Perineal Tear
Low Power Laser for Spontaneous Perineal Laceration
Scenario: spontaneous perineal laceration is an injury to the tissue in the perineum region, which can occur during vaginal delivery.
- Trial name
- LASER (NCT04914182)
- Testing
- LASER, CONTROL
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Pelvic Floor Dysfunction, Perineal Laceration
Perineal Protection Device for Reducing Perineal Trauma During Vaginal Delivery in First-time Mothers: a Multicenter Randomized Controlled Trial
The goal of this clinical trial is to determine whether using a soft perineal protection device (BabySlide®) in addition to standard manual perineal support during vaginal delivery can reduce the risk of perineal trauma in…
- Conditions
- Pelvic Floor Dysfunction, Perineal Laceration, Wound Dehiscence, Anal Incontinence
- Trial name
- PeriPROTECT (NCT07862660)
- Testing
- Perineal protection device, BabySlide, Standard manual perineal support
- Where
- Sweden
- Volunteers
- 4,226 people
- Sponsor
- Region Skane
Perineal Tear Resulting From Childbirth
Perineal Massage and Warm Compresses - RCT for Reduce Perineal Trauma During Labor
The aim of this study is to evaluate the effect of a combined perineal massage and warm compresses intervention on the perineum integrity during second stage of labor.
- Trial name
- PeMWaC (NCT05854888)
- Testing
- Perineal Massage and Warm Compresses (PeMWaC), Control Group (Hands-on)
- Where
- Portugal
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Obstetric Trauma, Infections
Oral Antibiotics After Obstetric Perineal Tear
The purpose of this study is to investigate if 3 dose of oral antibiotics administrated the first day after a vaginal delivery with a second degree obstetric tear will decrease the risk of infection and/or wound dehiscence…
- Conditions
- Obstetric Trauma, Infections, Wound Dehiscence
- Trial name
- REPAIR (NCT05830162)
- Testing
- Bioclavid (Amoxicillin and Clavulanic acid)
- Where
- Denmark
- Volunteers
- 442 people
- Sponsor
- Hanna Jangö
Obstetric Complication, Obstetric Trauma
Consequences of Obstetric Anal Sphincter Injuries on Maternal Psychology and Relationship Experience
The aim is to ascertain whether sustaining an Obstetric Anal Sphincter Injury negatively impacts intra-family relationships and increases the risk of mental health conditions, including a women's perception of herself and her…
- Conditions
- Obstetric Complication, Obstetric Trauma, Perineal Tear, Incontinence
- Trial name
- COMPaRE (NCT05935371)
- Where
- United Kingdom
- Volunteers
- 87 people
- Sponsor
- London North West Healthcare NHS Trust
Perineal Tear
Skin Glues Compared to Running Sutures for Perineal Skin Repair After Vaginal Delivery. A Randomized Controlled Trial
The incidence of a perineal tears during labor is 70 to 90%, while in 96% of the cases it's a minor perineal tear (grade 1). In about 3% to 4% the perineal tear is major and involve the external (grade 3) and the internal anal…
- Trial name
- NCT03983343
- Testing
- exofin®
- Where
- Israel
- Volunteers
- 182 people
- Sponsor
- HaEmek Medical Center, Israel
Episiotomy; Complications, Scar Tissue
Optimizing Postpartum Pelvic Health Through Self-Scar Tissue Massage of Episiotomy and Perineal Scar Tissue A Pilot RCT
The goal of this Pilot Randomized Control Trial (RCT) is to determine if a larger RCT evaluating the effect of self-scar tissue massage of episiotomy and/or vagina/perineal tear scar tissue on pelvic health outcomes is feasible.
- Conditions
- Episiotomy; Complications, Scar Tissue, Perineal Tear, Vaginal Tear Resulting From Childbirth
- Trial name
- EPIS (NCT05908292)
- Testing
- Pelvic Floor Scar Tissue Self-Scar Massage
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Vaginal Tear, Perineal Tear
Application of a Perineal Protection Device in Vacuum-assisted Births
Visible birth tears are common in vaginal births, especially in vacuum-assisted births. One aim of obstetrical work is to minimize such injuries by an adequate birth management , for example with a proper perineal support.
- Trial name
- NCT04370340
- Testing
- BabySlide
- Where
- Switzerland
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Perineal Tear and Episiotomy, Perineal Laceration, Tear, or Rupture During Delivery
Improving the Management and Prevention of Perineal Wound Dehiscence From Episiotomies Using Flaminal
The objectives of this study are to assess the effectiveness of Flaminal Forte in the treatment and prevention of perineal wound breakdown.
- Trial name
- FLAMINGO (NCT07468890)
- Testing
- Flaminal anti-microbial gel
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Perineum; Rupture, Perineum; Tear
In Vivo Evaluation of Perineal Mechanical Properties During Childbirth
The objective of this work is to evaluate perineal elasticity and deformation and the perineal stresses induced by the fetus during delivery.
- Conditions
- Perineum; Rupture, Perineum; Tear, Perineal Tear
- Trial name
- MecaPer (NCT05556304)
- Testing
- assessment in the 8th month of pregnancy and during delivery
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Second Degree Perineal Tear During Delivery - Delivered, Episiotomy; Complications
Perineal Local Infiltration Study
The prevalence of birth canal lacerations is more than 70% of all deliveries in Canada. The repair of such lacerations is usually done using a pre-existing epidural analgesia.
- Conditions
- Second Degree Perineal Tear During Delivery - Delivered, Episiotomy; Complications, Anesthesia, Local
- Trial name
- PLIS (NCT03672500)
- Testing
- Bupivacaine 0.5%+Epinephrine 50mc
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Perineal Laceration, Tear, or Rupture During Delivery
TRESPASS Clinical Study
The purpose of this study is to assess the superiority of a standardized perineal massage in the decrease in vagino-perineal lacerations.
- Trial name
- NCT06443736
- Testing
- Standardized perineal massage, Primary prevention
- Where
- Italy
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Azienda Sanitaria-Universitaria Integrata di Udine
Labor Complication
Comparison of Routine Versus Restrictive Episiotomy in Primigravida Women at Term.
The ongoing debate over routine versus selective episiotomy in primiparous term women underscores the necessity for updated local data.
- Trial name
- NCT07796685
- Testing
- Routine Episiotomy, Restrictive Episiotomy
- Where
- Pakistan
- Volunteers
- 466 people
- Sponsor
- Muhammad Aamir Latif
Perineal Tear, Episiotomy Wound
Continuous Versus Discontinuous Suture in the Perineals Lesions
The hypothesis: Women who have a continuous suture have better health outcomes Two types of sutures were placed in the perineal lesion, using different techniques.
- Trial name
- NCT03825211
- Testing
- Continuous suture in the perineals lesions, Discontinuous suture in the perineals lesions
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Jaén