Clinical trials: Periodontal Bone Loss
Tooth Loss
Implant Survival After Insertion of Bone Level Tapered (BLT) Implant Ø 2.9 mm in the Clinical Practice Setting
The Straumann Bone Level Tapered (BLT) implant Ø 2.9 mm implant was developed to allow treatment of patients with single tooth gaps of small dimensions in the lateral and central incisor positions in the mandible and in the…
- Trial name
- NCT02699866
- Testing
- BLT Implant Ø 2.9 mm
- Where
- 5 sites in Germany
- Volunteers
- 46 people
- Sponsor
- Institut Straumann AG
Maxillofacial Bone Defects, Alveolar Bone Atrophy
Gene-activated Matrix for Bone Tissue Repair in Maxillofacial Surgery
The purpose of this study is to evaluate safety and efficacy of gene-activated matrix ("Nucleostim") for regeneration of bone tissue in maxillofacial area.
- Conditions
- Maxillofacial Bone Defects, Alveolar Bone Atrophy, Jaw Fractures, Maxillofacial Bone Deformities
- Trial name
- NCT02293031
- Testing
- Gene-activated matrix "Nucleostim"
- Where
- 2 sites in Russia
- Volunteers
- 12 people
- Sponsor
- NextGen Company Limited
Alveolar Bone Loss
Localized Alveolar Ridge Augmentation With Space Maintenance Devices
The purpose of this research study is to determine whether this study treatment can improve the bone structure of the upper front part of the jaw in patients who are scheduled for surgery to have a dental implant(s) placed into…
- Trial name
- Ridge Mesh (NCT00991432)
- Testing
- INFUSE® Bone Graft
- Where
- 8 sites in United States
- Volunteers
- 10 people
- Sponsor
- Medtronic Spinal and Biologics
Alveolar Bone Loss, Periodontal Diseases
GUIDOR® Growth Factor Enhanced Bone Graft Substitute for the Treatment of Periodontal Defects 6-months Post-Surgery
GUIDOR Growth Factor Enchanted Bone Graft Substitute (GFeBGS) when used in periodontal surgery will shown greater gum and bone regeneration when compare to bone graft substitute alone. Also, to find the optimal dose.
- Trial name
- NCT01728844
- Testing
- beta-tricalcium phosphate alone, GFeBGS 0.1%, GFeBGS 0.3%
- Where
- 6 sites in United States
- Volunteers
- 88 people
- Sponsor
- Sunstar Americas
Peri-implantitis, Peri-implant Bone Loss
Access to Probing and Peri-implant Diseases
This multicenter cross-sectional study aims to evaluate the association between access to peri-implant probing and radiographic peri-implant bone loss.
- Trial name
- NCT07557459
- Testing
- Peri-implant probing
- Where
- 9 sites in Spain
- Volunteers
- 281 people
- Sponsor
- Arrow Development
Tooth Loss, Edentulism
PMCF Study on the Effectiveness and Safety of BIODENTOSS® and DWC® Dental Implants and Superstructures
This prospective, single-center, interventional post-market clinical follow-up (PMCF) study aims to evaluate the early-term (24 months post-implantation) safety and efficacy of CE-marked BIODENTOSS® and DWC ® Dental Implants and…
- Trial name
- NCT07633665
- Testing
- BIODENTOSS Bone-Level Dental Implant and Superstructures, DWC Bone-Level Dental Implant and Superstructures
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Değirmenci Otomotiv ve Metal Endüstri A.Ş.
Dental Implants, Ceramic Implant
Zirconia Implants: Practice-based Evidence
This study is a prospective case series clinical study to examine the effectiveness of Ceramic dental implants manufactured by Swiss Dental Solutions (SDS).
- Trial name
- SDS (NCT06314425)
- Testing
- Immediate dental implants placements on fresh sockets after tooth extraction
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Swiss Dental Solutions
Alveolar Bone Loss in Mandible, Edentulous Alveolar Ridge In Mandible
Clinical Study of INFUSE® Bone Graft Compared to Autogenous Bone Graft for Vertical Ridge Augmentation
The purpose of this study is to evaluate the INFUSE® Bone Graft as an alternative to autograft for bone formation in the back of the mandible (lower jaw) prior to placing dental implants.
- Trial name
- NCT01308996
- Testing
- INFUSE® Bone Graft, Autogenous bone graft from tibia or iliac crest
- Sponsor
- Medtronic Spinal and Biologics
Tooth Loss
Comparison of Straumann BoneCeramic vs. Allograft Bone in Extraction Sockets
The primary objective of this study is to evaluate the implant stability at the time of abutment placement on implants placed in healed extraction sockets treated with Straumann BoneCeramic (SBC) versus Freeze Dried Bone…
- Trial name
- NCT00782236
- Testing
- Bone Graft Material
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Institut Straumann AG
Alveolar Bone Loss, Periodontal Bone Loss
Pilot Study on MD05 in Comparison With Open Flap Debridement in Patients Undergoing Periodontal Surgery
The purpose of the study is to gain experience of safety and efficacy with MD05 in man in alveolar bone regeneration.
- Trial name
- NCT00519155
- Testing
- MD05 and open flap debridement, Open flap debridement
- Where
- Hungary
- Volunteers
- 20 people
- Sponsor
- Scil Technology GmbH
Periodontitis, Alveolar Bone Loss
Phase 3 Clinical Trial of Periodontal Tissue Regeneration Using Fibroblast Growth Factor-2(Trafermin)
This study aims to verify the effectiveness of Trafermin (recombinant human basic fibroblast growth factor) in stimulating regeneration of periodontal tissue lost by periodontitis and to evaluate the safety of such stimulation.
- Conditions
- Periodontitis, Alveolar Bone Loss, Periodontal Attachment Loss
- Trial name
- NCT00734708
- Testing
- Trafermin (genetical recombination)
- Where
- 21 sites in Japan
- Volunteers
- 328 people
- Sponsor
- Kaken Pharmaceutical
Oral Bone Defect, Maxillofacial Bone Defect
Performance and Safety of the Resorbable Collagen Membrane "Ez Cure"
The evaluation of the clinical data has demonstrated the conformity of the Resorbable Collagen Membrane (RCM), EZ CureTM, with the relevant essential requirements for its use in periodontal applications.
- Conditions
- Oral Bone Defect, Maxillofacial Bone Defect, Periodontal Bone Loss, Alveolar Bone Loss
- Trial name
- NCT03978962
- Testing
- Guided Tissue Regeneration
- Where
- 2 sites in France
- Volunteers
- 56 people
- Sponsor
- Biomatlante
Preservation of Alveolar Bone Height With PLGA Bioscaffold
Radiographic Assessment of Bone Regeneration in Alveolar Sockets With PLGA Scaffold
After extraction of a tooth, the bony socket heals naturally but due to the absent of the tooth and any presence of support in the socket, bone resorption occur both vertically and bucco lingually or bucco palataly.
- Trial name
- NCT00836797
- Where
- 2 sites in India, Singapore
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bio-Scaffold International Pte Ltd
Tooth Loss
Bone Level Tapered Multi-Center Study
The aim of this randomized, controlled, multi-center study is to assess the clinical and radiographic outcomes of using a Straumann® Bone Level Tapered implant for immediate implantation following extraction of a tooth in the…
- Trial name
- NCT02569671
- Testing
- Straumann Bone Level Tapered Implant - Immediate Placement, Straumann Bone Level Tapered Implant - Delayed Placement
- Where
- 3 sites in United States
- Volunteers
- 53 people
- Sponsor
- Institut Straumann AG
Jaw, Edentulous, Partially, Alveolar Bone Loss
Straumann Bone Ceramic Versus BioOss in Sinus Elevation
Straumann Bone Ceramic (SBC) and BioOss will be used as bone grafting materials when there is a need for bone augmentation in the posterior upper jaw. 9 months later the bone formation is evaluated.
- Trial name
- NCT00900822
- Testing
- Straumann Bone Ceramic, BioOss
- Where
- Sweden
- Volunteers
- 11 people
- Sponsor
- Institut Straumann AG
Bone Loss, Alveolar
A Randomized Control Trial Phase (IIIa) Unicentric, Placebo Controlled, Double-Blinded Efficacy and Safety of Topical Alendronic Acid on Alveolar Bone Remodeling After Tooth Extraction
The purpose of the study is to determine the efficacy and safety of the effects of a topical medication on bone remodeling after dental extraction, in order to establish whether such treatment can be a new therapeutic option for…
- Trial name
- XEOLAS (NCT05602493)
- Testing
- Soludronate®, sterile saline
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Xeolas Pharmaceuticals Limited
Bone Cysts, Bone Atrophy
Gene-activated Bone Substitute for Maxillofacial Bone Regeneration
The purpose of this study is to evaluate the safety and efficacy of the gene-activated bone substitute consisting of octacalcium phosphate and plasmid DNA encoding vascular endothelial growth factor (VEGF) for maxillofacial bone…
- Conditions
- Bone Cysts, Bone Atrophy, Bone Deformity, Bone Fracture
- Trial name
- NCT03076138
- Testing
- Gene-activated matrix (OCP + plasmid DNA with VEGF gene)
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- Histograft Co., Ltd.
Alveolar Bone Loss, Alveolar Ridge Pathology | Gingiva | Dental
Comparative Study of Gene-activated Bone Substitute and Xenogenic Bone Matrix in Alveolar Ridge Augmentation
The study aim is to compare the effectiveness of two bone substitutes, the gene-activated bone substitute based on octacalcium phosphate and plasmid DNA encoding VEGFA gene and xemogenic deproteinized bone matrix, mixed with…
- Trial name
- NCT04511689
- Testing
- gene-activated bone substitute mixed with autobone
- Where
- Russia
- Volunteers
- 24 people
- Sponsor
- Histograft Co., Ltd.
Alveolar Bone Loss
Localized Alveolar Ridge Augmentation With Dental Implant
The purpose of this research study is to shorten the treatment time course for patients who are scheduled for surgery to have a dental implant(s) placed into the upper front part of their mouths and need to have more bone in…
- Trial name
- RidgeDI (NCT00991965)
- Testing
- INFUSE® Bone Graft
- Where
- 6 sites in United States
- Volunteers
- 8 people
- Sponsor
- Medtronic Spinal and Biologics