Clinical trials: Periodontal Diseases
Periodontitis
Effectiveness of Periodontal Therapy on Periodontal Bacteria
In light of the controversy that are already approved but that however still exists regarding the efficacy and influence of the protocols for the management of Periodontitis, the aim of this study was to evaluate, at 6 months…
- Trial name
- NCT04735692
- Testing
- Full mouth or quadrant SRP
- Where
- Italy
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Catania
Dental Implants, Tooth Loss
Immediate Load in Dental Implants Using Conventional Drilling and Piezoelectric Osteotomy on Aesthetic Zone.
Compare the survival rate of the implants placed using the ultrasonic technique and placed using conventional drilling, with an immediate load on the aesthetic zone.
- Trial name
- NCT04497571
- Testing
- Piezoelectric osteotomy., Conventional drilling
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Periodontitis, Periodontal Inflammation
Indocyanine-green Mediated Photosensitizer VS Aloe Vera Gel: Adjunct Therapy to Scaling and Root Planing in Patients With Chronic Periodontitis
For proving the potential of tropical medicaments on clinical parameters of periodontitis, a comprehensive assessment is required between therapeutic medicaments.
- Trial name
- NCT04964167
- Testing
- Plant extract
- Where
- 2 sites in Pakistan, Saudi Arabia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Apical Periodontitis, Postoperative Pain
Cryotherapy on Inflammatory Profile and Postoperative Pain Levels in Endodontic Infections
The aim of this study is to evaluate the effects of cryotherapy applications on the inflammatory cytokine and collagenase matrix metalloproteinase levels during root canal treatment and postoperative pain intensity and incidence.
- Conditions
- Apical Periodontitis, Postoperative Pain, Cytokine Levels
- Trial name
- NCT04798144
- Testing
- Distilled water irrigation kept at 2.5°C degree, Distilled water irrigation kept at room temperature
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Periodontitis (Stage 3)
Evaluation of The Periodontal Parameters Following Non-Surgical Periodontal Therapy With and Without Adjunctive Use of Injectable Platelet Rich Fibrin: A Randomized Controlled Clinical Trial
This randomized controlled clinical trial aims to evaluate the effectiveness of non-surgical periodontal therapy (NSPT) with and without the adjunctive use of injectable platelet-rich fibrin (I-PRF) in patients with chronic…
- Trial name
- NCT07090265
- Testing
- non-surgical periodontal therapy, non-surgical periodontal therapy + I-PRF
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingivitis
Powered Toothbrush Versus Manual Toothbrush on Plaque and Gingivitis After a Six-Week Period of Home Use
The goal of this clinical trial is to learn if powered toothbrushing is more effective than manual toothbrushing in removing dental plaque. It will also learn about the safety of power toothbrushing.
- Trial name
- NCT07691814
- Testing
- power toothbrush, manual toothbrush
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Periodontal Disease
Genetics of Periodontal Diseases in Chinese (Taiwan)
A retrospective case control study to validate the association between Interleukin-1 gene variations and adult chronic periodontal disease in Chinese (Taiwan).
- Trial name
- NCT01675336
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
Alveolar Bone Loss
Effectiveness of Alveolar Bone Preservation in Alveoli With Infectious Process
Alveolar ridge preservation (ARP) is a surgical technique that aims to minimize the degree of dimensional changes following extraction.
- Trial name
- NCT06661863
- Testing
- alveolar ridge preservation with bioactive glass, alveolar ridge preservation with autologous bone
- Where
- Ecuador
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
Peri-Implant Health, Peri Implant Mucositis
Impact of Smoking on Immune Responses in Peri-implant Health and Disease
Peri-implant diseases are inflammatory conditions affecting the gums and bone around dental implants. Peri-implant mucositis causes inflammation in the gums, while peri-implantitis can also lead to bone loss and, in severe cases…
- Conditions
- Peri-Implant Health, Peri Implant Mucositis, Peri-implantitis
- Trial name
- NCT07750171
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Gazi University
Periodontal Bone Loss, Periodontal Pocket
Treatment of Intraosseous Periodontal Defects With Hyaluronic Acid
The aim of the present investigation will be evaluate the healing of periodontal intraosseous defects following Minimally Invasive Non Surgical Debridement (MINSD) and application of a hyaluronic acid-based gel, compared to MINSD…
- Trial name
- NCT05188898
- Testing
- MINSD and Hyaluronic acid, MINSD
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Federico II University
Alveolar Process Atrophy
Marginal Bone and Soft Tissue Alterations After Use of OsseoSpeed EV Profile Implants
Evaluation of the marginal bone and soft tissue alterations after the OsseoSpeed™ EV Profile implants placement in anterior maxilla.
- Trial name
- NCT04243421
- Testing
- Implantation
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Alveolar Bone Loss
Efficacy of Customized Zirconia Sheet vs PTFE as a Non-resorbable Barrier in Maxillary Alveolar Ridge Augmentation
The goal of this clinical trial is comparing the efficacy of custom-made zirconia sheet versus Polytetrafluoroethylene as a non-resorbable barrier in maxillary alveolar ridge augmentation.
- Trial name
- NCT06227455
- Testing
- Maxillary alveolar ridge augmentation
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Chronic Periodontitis
RELATIONSHIP BETWEEN INITIAL PROBING DEPTH AND CHANGES IN CLINICAL PARAMETERS FOLLOWING NON-SURGICAL PERIODONTAL TREATMENT IN CHRONIC PERIODONTITIS PATIENTS
Aim: The aim of this study was to evaluate the relationship between initial probing depth (IPD) and changes in clinical parameters following non-surgical periodontal treatment (NPT) in chronic periodontitis patients.
- Trial name
- NCT02861326
- Testing
- Gracey Curettes
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Marmara University
Gingivitis
Clinical Study to Investigate a New Mouthwash in Reducing Plaque and Helping Prevent Gum Problems on Dental Implants Over a 6-month Period of Product Use
The objective of this six-month clinical research study is to evaluate the clinical efficacy of a new mouthwash on helping prevent gum problems (gingival index scores ) in adults as compared to a control mouthwash.
- Trial name
- NCT06770114
- Testing
- Cetylpyridinium Chloride, Zinc Lactate and Hyaluronic Acid Mouthwash, PhosFlur Mouthwash
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Periodontitis
Evaluation of Adipose Derived Stem Cells Exo.in Treatment of Periodontitis
The adipose stem cells exosomes will be extracted from adipose stem cells isolated autogenously from the patient to be injected locally into the periodontal pockets in order to evaluate their regenerative effect.
- Trial name
- exosomes (NCT04270006)
- Testing
- adipose derived stem cells exosomes
- Where
- 2 sites in Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Periodontal Diseases, Dental Plaque
Oral Health Literacy Tailored Communication
The purpose of this study to investigate attitude, oral health literacy and psychological factors in order to evaluate if these factors are important for oral health in adults.
- Conditions
- Periodontal Diseases, Dental Plaque, Dental Calculus, Sialorrhea
- Trial name
- NCT01118143
- Testing
- Tailored oral health literacy instruction
- Where
- 2 sites in Norway
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Periodontal Pocket
Glucosamine Sulphate Versus Ginger in Non-Surgical Periodontal Therapy
Glucosamine (GlcN) is an N-deacetyl amino monosaccharide sugar derived from complete hydrolysis of chitosan in which it is important vector for chondroitin and keratin sulfate, while on the other hand, medicinal plants became a…
- Trial name
- NCT06200415
- Testing
- Glucosamine Sulfate, Ginger Oil
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Gingival Recession, Localized, Gingival Recession
Root Coverage With Tunneling Technique With Connective Tissue Versus Coronal Advancement Flap Technique.
This is a randomized triple-blind clinical trial. This comparative clinical study investigates the efficacy of root coverage using two periodontal techniques: the tunneling technique and the coronal advancement technique.
- Trial name
- NCT06228534
- Testing
- Root coverage with tunneling technique
- Where
- Ecuador
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Luis Alberto Chauca Bajaña
Periodontitis
Study on the Relationship Between Periodontitis and Renal Disease
Analysis of inflammatory markers in periodontitis and patients with early and middle stage renal disease.
- Trial name
- NCT02417363
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Periodontal Diseases
Deep Learning-Based Measurement of Keratinized Gingiva Width Using Smartphone-Acquired Clinical Images
This study aims to develop and validate an artificial intelligence-based system for automated measurement of keratinized gingiva width using smartphone-acquired intraoral clinical photographs.
- Trial name
- NCT07689552
- Testing
- Artificial Intelligence-Based Keratinized Gingiva Width Assessment
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
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