Clinical trials: Periodontal Surgery
Platelet-rich Fibrin
Effect of Platelet-rich Fibrin on Soft Tissue, Periodontal Pocket Healing and Alveolar Bone Height After Third Molar Surgery
A Randomized, controlled clinical trial and split-mouth design was performed to assess and compare the effect of platelet-rich fibrin (PRF) on soft tissue healing, periodontal pocket depth and alveolar bone height distal to…
- Trial name
- NCT05866965
- Testing
- PRF, standard third molar surgical removal
- Where
- Vietnam
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Lam Cu Phong
Periodontitis, Menopause
Evaluation of Periodontal Response to Non Surgical Therapy in Pre and Post Menopausal Women With Periodontitis
The present study was evaluated periodontal status in pre and post-menopausal women with periodontitis following non-surgical therapy.
- Conditions
- Periodontitis, Menopause, Plaque, Inflammation
- Trial name
- EPRNPPMP (NCT02718014)
- Testing
- scaling and root planing (srp)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Healing Surgical Wounds, Periodontitis
Modified Vertical Internal Mattress Suture Versus Simple Loop Interrupted Suture.
Aim of study was clinical comparative evaluation of using modified vertical internal mattress suturing technique and simple loop interrupted suturing technique in the outcome of modified Widman flap surgery for the management of…
- Trial name
- NCT03556163
- Testing
- Modified vertical internal mattress sutures + MWF surgery., Simple loop interrupted sutures + MWF surgery.
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Recession
Two Techniques for Root Coverage With a Xenogeneic Collagen Matrix
Gingival recessions are often successfully treated by coronally advanced flap technique (CAF) associated with subepithelial connective tissue grafts (SCTG).
- Trial name
- NCT02129504
- Testing
- root coverage comparing two techniques
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Periodontal Diseases
Effect of Internal and External Micro-needling in Treatment of Stage III Periodontitis
Periodontitis is a dysbiotic disease characterized by the destruction of the periodontium (alveolar bone, cementum, periodontal ligament, gingiva) and considered the main cause of tooth loss which is linked to a change in the…
- Trial name
- NCT06578403
- Testing
- external microneedling, minimally invasive non- surgical periodontal therapy, internal micro_needling
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Periodontitis
Air Polishing as an Adjunct in Non-surgical Periodontal Therapy
Periodontal disease is an infection that causes inflammation and destruction of the tooth supporting structures, and if untreated, will eventually lead to tooth loss.
- Trial name
- NCT04178291
- Testing
- Ultrasonic scaler and Gracey currettes, Air polishing with erythritol powder
- Where
- Malaysia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Regenerative Inflammation
Evaluation of Platelet Rich Fibrin Matrix as Regenerative Material in Intraosseous Defects
Technological advancement has led to the development of concentrated platelets, by means of centrifugation, popularly known as Platelet concentrates which seem to be a convenient approach to obtain autologous growth factors.
- Trial name
- NCT03616925
- Testing
- Platelet Rich Fibrin Matrix kit, surgical open flap debridement
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- KLE Society's Institute of Dental Sciences
Periodontitis, Chronic Periodontitis (Disorder)
Cofilin-2 (rs80358250) and Lactoferrin (rs1126478) Polymorphism and Protein Levels With Non Surgical Periodontal Therapy in Periodontitis Patients With and Without CHD
Periodontitis is a chronic multifactorial inflammatory disease associated with the accumulation of dental plaque and characterized by progressive destruction of the teeth-supporting apparatus, including the periodontal ligament…
- Conditions
- Periodontitis, Chronic Periodontitis (Disorder), Coronary Heart Disease
- Trial name
- NCT07353606
- Testing
- Scaling and root planing
- Where
- 2 sites in India
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Periodontitis
Bactericidal Permeability Protein Inhibitor and Interleukin-1beta Levels After Non-surgical Periodontal Treatment
The aim of this study was to examine the relationship between healing response after non-surgical periodontal treatment and baseline gingival crevicular fluid (GCF) levels of bactericidal/permeability-increasing protein (BPI) and…
- Trial name
- NCT06354504
- Testing
- Non-surgical periodontal treatment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Intrabony Periodontal Defect
Clinical and Radiographic Evaluation of the Entire Papilla Preservation (EPP) Technique Versus Modified Minimally Invasive Surgical Technique (M-MIST) in Treatment of Intraosseous Defects in Patients With Stage III Periodontitis: A Randomized Clinical Trial
Periodontitis is defined as loss of periodontal attachment due to microbial associated host mediated inflammation. This would lead to the apical migration of the junctional epithelium allowing the bacterial biofilm to undergo…
- Trial name
- NCT04100798
- Testing
- Entire Papilla Preservation technique, Modified Minimally invasive Surgical Technique
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Diseases
Application of Hyaluronic Acid in Diabetes
sub gingival application of hyaluronic acid create great clinical improvement of periodontal pocket treatment.
- Trial name
- NCT05543434
- Testing
- Hyaluronic acid
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis
Salivary Proteome in Response to Non-surgical Periodontal Treatment
This study aims to investigate salivary proteome changes in periodontitis patients before and after non-surgical treatment. Ten systemically healthy and non-smoker individuals with stage III, grade C periodontitis underwent…
- Trial name
- NCT05952895
- Testing
- Conventional quadrant-wise scaling and root planing (SRP)
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Gingival Recession, Localized, Postoperative Morbidity
Palatal Wound Healing After Free Gingival Graft Surgery
This randomized controlled clinical trial aims to evaluate the effects of topical triamcinolone acetonide application on wound healing and patient-reported outcomes at the palatal donor site following free gingival graft (FGG)…
- Conditions
- Gingival Recession, Localized, Postoperative Morbidity, Palatal Donor Site Wound Healing
- Trial name
- NCT07409571
- Testing
- kollajen membran (Cytoplast™ RTMFOAM™, Osteogenics Biomedical Inc., Texas, ABD), triamcinolone acetonide
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Periodontal Diseases, Periodontal Inflammation
Minimally Non Surgical Periodontal Therapy Compared to Traditional Approach
This study aims to evaluate the clinical results of non-surgical periodontal therapy performed with micro-instruments compared to traditional approach (standard curettes) after 6 months of follow-up.
- Trial name
- NCT05060601
- Testing
- Gracey micro-curettes, Standard Gracey curettes
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federico II University
Chronic Periodontitis, Generalized, Moderate
Er:YAG Laser Treatment of Moderate Chronic Periodontitis
The Er:YAG laser possesses specific characteristics allowing to be used in non-surgical periodontal treatment. The aim of the resent study was to evaluate the long-term clinical effectiveness of Er:YAG laser monotherapy in the…
- Trial name
- NCT05217823
- Testing
- Er:YAG laser, hand instruments
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Periodontal Disease, Non-diseased Patients
The Importance of Periostin in Periodontal Health and Disease
The goal of this study is to determine the clinical importance of Periostin in oral health and disease. The long-term goal will be to develop practical applications for the diagnosis, treatment, prevention and cure of human…
- Trial name
- NCT01180920
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Apical Periodontitis
Effect of Different Instrumentation Technique on Endodontic Outcome
Aim: To evaluate and compare the outcome of primary endodontic treatment following use of different instrumentation techniques. Materials and methods: Study subjects were recruited from the pool of patients referred for the…
- Trial name
- NCT03278054
- Testing
- Root Canal Treatment with hand instruments, Root canal treatment with Protaper instruments, Root canal treatment with hybrid instrumentation
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontitis
A Clinical Trial to Study the Effect of a Drug, Curcumin in Patients With Periodontitis
The study will follow a parallel arm, randomised, double blinded, placebo controlled design. There will be two groups Group 1 = receiving 1% curcumin chips after routine scaling and root planing (n=20) Group 2 = receiving placebo…
- Trial name
- NCT03790605
- Testing
- 1 % curcumin chip, Scaling and root planing
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KLE Society's Institute of Dental Sciences
Chronic Periodontitis
Evaluation of SilOss® in Periodontal Surgery
Siloss® (Azurebio, Madrid, Spain) is a synthetic and inorganic bone graft material and is composed of a dicalcium phosphate anhydrous (monetite), hydroxyapatite (HA), and amorphous silica and trace amounts of zinc.
- Trial name
- NCT02639572
- Testing
- Siloss® bone graft, Hydroxyapatitie Bone graft
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Wound Healing
Effects of CGF and Collagen Fleece on Palatal Donor Site Healing: A Randomized Clinical Trial
This study investigated whether applying Concentrated Growth Factor (CGF) or Collagen Fleece (CF) to the palatal donor site after autogenous soft tissue graft harvesting could improve wound healing and reduce postoperative…
- Trial name
- PAL-HEAL (NCT07367165)
- Testing
- Concentrated Growth Factor (CGF), Collagen Fleece (CF), Collagen Sponge (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Inonu University