Clinical trials: Periodontis
Periodontis, Aggressive Periodontitis
Single-cell and Spatial Transcriptomic Profiling of Gingival Tissues in Aggressive and Chronic Periodontitis: Deciphering Cellular Heterogeneity and Inflammatory Microenvironment Features
The goal of this observational study is to investigate cellular heterogeneity and inflammatory microenvironment features in gingival tissues from patients with aggressive periodontitis compared to chronic periodontitis and…
- Trial name
- NCT07487272
- Where
- China
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Periodontitis Generalized
Periodontal Therapy Effect on the Ratio of TNF-α to IL-10 in Periodontis With/Out DM
Periodontitis is a chronic inflammatory disease affecting the periodontium, characterized by irreversible damage to the gingiva, periodontal ligament, and alveolar bone.
- Trial name
- NCT06539039
- Testing
- non surgical periodontal therapy
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Periodontis, Atherosclerosis Cardiovascular Disease
Evaluation of the Association Between the Effects of Generalized Stage 3 and 4 Periodontitis on Arterial Stiffness and Cardiovascular Risk: the PAROCAR Study
Periodontal diseases are chronic inflammatory conditions affecting nearly half of the adult population and are associated with systemic inflammatory responses.
- Trial name
- PAROCAR (NCT07263113)
- Testing
- Periodontal examination and pulse wave velocity
- Where
- France
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Cardiovascular Disease in Obstructive Sleep Apnea
Impact of Treatment of Periodontis on Endothelial Function in Patients With Obstructive Sleep Apnea
Evaluation of the add-on effect on endothelial dysfunction of treatment of periodontitis in patients with chronic periodontitis and severe obstructive sleep apnea treated by CPAP.
- Trial name
- EndothSAS (NCT02573116)
- Testing
- scaling and root planing
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Hopital Foch
Periodontitis, Chronic Kidney Disease
Impact of Non Surgical Periodontal Therapy on Cystatin C Levels
Study the effect of non-surgical periodontal therapy on cystatin C levels in gingival crevicular fluid and serum in both healthy patients and patients with renal impairment.
- Trial name
- NCT07103421
- Testing
- Non-Surgical Periodontal Therapy
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Latakia University