Clinical trials: Periodontitis, Adult
Chronic Periodontitis With Mandibular Degree 2 Furcation Defects
Boric Acid in Degree 2 Furcation Defect
The purpose of this double-masked, randomized, controlled clinical trial was to evaluate the effects of subgingival delivery of boric acid gel as an adjunct to scaling and root planing (SRP) on clinical and radiographic…
- Trial name
- NCT02738515
- Testing
- 0.75 % Boric Acid
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Periodontitis, Adult
Clinical Efficacy of NST With Adjunctive Local Delivery of Ozonated Olive Versus Curcumin Gel in Stage II Grade B Periodontitis.
The aim of this clinical trial is to evaluate the effectiveness of local delivery ozonated olive gel versus curcumin gel as adjunct to scaling and root planing in the treatment of stage II grade B periodontitis in on both males…
- Trial name
- NCT07184268
- Testing
- full mouth non-surgical scaling
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Diseases
Non-surgical Treatment of Chronic Periodontitis With an Adjunctive Vitamin E and Coenzyme Q10 Supplementation
Non-surgical treatment of chronic periodontitis with vitamin E and coenzyme Q10 supplementation
- Trial name
- NCT06373848
- Testing
- Receive 30 mg of Coq10
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Chronic Periodontitis (CP) Subjects.
"Effect of Scaling and Root Planing on Liver Function Test (Alanine Aminotransferase and Aspartate Aminotransferase) in Systemically Healthy - Chronic Periodontitis Subjects: a Clinical Trial."
Aim: To evaluate effect of non- surgical periodontal therapy on liver function in systemically healthy chronic periodontitis (CP) subjects.
- Trial name
- NCT02583841
- Testing
- Scaling and root planing
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Periodontal Disease
Locally Delivered Doxycycline Adjunct to Nonsurgical Periodontal Therapy.
The aim of this clinical study is to asses the effect of ultrasonic periodontal debridement associated to locally delivered doxycycline (20%) by PLGA microspheres on chronic generalized periodontitis treatment.
- Trial name
- NCT02487186
- Testing
- Doxicicline, Full-mouth debridment
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Campinas, Brazil
Periodontitis
Control of Periodontal Infections
The purpose of this study is to test combined effects of scaling and root planing with periodontal surgery, systemically administered amoxicillin and metronidazole, and/or local tetracycline on pocket depth reduction and…
- Trial name
- NCT01098448
- Testing
- scaling and root planing, local tetracycline, systemic metronidazole and amoxicillin
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- The Forsyth Institute
Periodontitis Chronic Generalized Severe
Flurbiprofen Versus Aloe Vera Gel in the Treatment of Chronic Periodontitis in Smoking Patients.
This study aims to evaluate clinically the efficacy of flurbiprofen gel in comparison to Aloe Vera gel as adjunctive to SRP in the reduction of periodontal pockets in patients with chronic periodontitis in smoking patients.
- Trial name
- NCT06041178
- Testing
- 2.5% flurbiprofen, 98% aloe vera
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Beirut Arab University
Mild and Moderate Chronic Periodontitis
Effect of Probiotic Lozenge on Gingivitis and Periodontitis
The oral cavity is mostly influenced by general health. The oral microbiota which is as complex as the gastro-intestinal or vaginal microbiota are considered to be difficult therapeutic targets.
- Trial name
- NCT02203812
- Testing
- Probiotic Arm
- Where
- India
- Volunteers
- 32 people
- Sponsor
- CD Pharma India Pvt. Ltd.
Periodontitis, Adult
Locally Delivered Minocycline in Advanced Periodontitis
Local drug delivery provides higher concentrations in the availability of the drug at the specific infected sites with the advantage of sustained release.
- Trial name
- NCT04076098
- Testing
- Minocycline Hydrochloride
- Where
- Malaysia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahsa University
Chronic Periodontitis Complex
Antibiotic and Probiotic Therapies in the Adjuvant Treatment of the Chronic Periodontitis.
Currently, with the increase of bacterial resistance to antibiotics associated with its side effects, it is necessary to find other adjuncts to combat the disease that are an alternative to the use of antibiotics.
- Trial name
- NCT03692819
- Testing
- Amoxicillin 500 Mg, Lactobacillus reuteri Oral Drops
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Chronic Periodontitis
1.2% Atorvastatin and 1.2% Simvastatin in Treatment of Chronic Periodontitis
Background: Statins are the recently evolved agents that aid in periodontal regeneration and ultimately attaining periodontal health.
- Trial name
- NCT02060032
- Testing
- 1.2% Atorvastatin local drug delivery, 1.2% simvastatin local drug delivery
- Volunteers
- 96 people
- Sponsor
- Government Dental College and Research Institute, Bangalore
Periodontal Diseases, Diabetes Mellitus
Comparison of Two Oral Hygiene Routines on the Glycemic Control for Type 2 Diabetes Patients With Chronic Periodontitis
This study aims to compare two common oral hygiene routines on the improvement of glycemic control and oral health parameters in moderate to severe periodontitis patients with uncontrolled type 2 diabetes (T2DM).
- Trial name
- NCT05260814
- Testing
- Electric toothbrush with smart phone app
- Volunteers
- 40 people
- Sponsor
- Harvard School of Dental Medicine
Periodontitis, Adult
To Evaluate the Effects of Systemic Probiotics & Antibiotics and Local Application of Antibiotics As an Adjuvant to NSPT
Background: Periodontitis is defined as "an inflammatory disease of the supporting tissues of the teeth caused by specific microorganisms or groups of specific microorganisms, resulting in progressive destruction of the…
- Trial name
- NCT06570863
- Testing
- Antibiotics(doxycycline), Probiotics, Metronidazole gel 25%
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dr fizza khalid
Healthy Adult Participants, Periodontal Disease
Clinical, Microbiological and Immunological Effects of the Adjuvant Use of Systemic Antibiotics and Probiotics in the Non-surgical Treatment of Periodontitis
Although robust evidence supports the benefits of antibiotics in periodontal treatment, the potential adverse effects of this therapy cannot be overlooked.
- Trial name
- NCT07592416
- Testing
- Amoxicilin and Metronidazole, Probiotic Therapy
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Chronic Periodontitis, Type2 Diabetes
1.2% Rosuvastatin Subgingivally Delivered In Chronic Periodontitis With Type 2 Diabetes Mellitus
The purpose of the present study was to evaluate the effects of subgingival delivery of 1.2% Rosuvastatin (RSV) gel as an adjunct to scaling and root planing in chronic periodontitis (CP) with Type 2 diabetes mellitus patients.
- Trial name
- NCT02985099
- Testing
- SRP plus Rosuvastatin gel
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Chronic Periodontitis
1.2% Rosuvastatin Gel As A Local Agent In Smokers With Chronic Periodontitis
The purpose of the present study was to evaluate the effects of subgingival delivery of Rosuvastatin gel as an adjunct to scaling and root planing in Smokers With Chronic Periodontitis (CP) patients.
- Trial name
- NCT03043196
- Testing
- SRP plus Rosuvastatin gel
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Research Institute, Bangalore
Periodontal Disease, Atherosclerosis
Assess the Effect of Treating Periodontal Disease on Cardiovascular Function in Young Adults
We propose to examine a population of Native Americans who have had little or no dental care, and to determine if periodontal disease is associated with early signs of vascular dysfunction or systemic inflammation.
- Trial name
- NCT01376791
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Chronic Periodontitis
Evaluation of Indian Gooseberry/ Amla in the Management of Chronic Periodontitis
This study aimed to evaluate the influence of amla (Emblica officinalis) on patients with chronic generalized periodontitis, using a single-blind, randomized controlled study design. 1.
- Trial name
- NCT07531823
- Testing
- Scaling and root planing + Amla, Scaling and root planing
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Mahatma Gandhi Postgraduate Institute of Dental Sciences
Periodontitis, Adult
Early Versus Delayed Orthodontic Treatment After Periodontal Surgery on Periodontal Health in Periodontally Compromised Patients
RESEARCH QUESTION: Will there be a difference in periodontal health of two groups of periodontally compromised orthodontic patients with early and delayed start of orthodontic treatment after periodontal surgery? Population…
- Trial name
- NCT05466253
- Testing
- Fixed Orthodontic treatment
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Chronic Periodontitis
Study to Compare Laser Assisted New Attachment Procedure (LANAP) to Traditional Treatments of Chronic Periodontitis
The purpose of this study is to compare the Laser Assisted New Attachment Procedure (LANAP protocol) using the Free-running (FR) Pulsed Neodimium: Yttrium aluminium garnet (Nd:YAG) laser to Scaling and Root Planing (SRP) alone…
- Trial name
- LANAP (NCT01282229)
- Testing
- LANAP
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Institute for Advanced Laser Dentistry